Liselot Dewachter
@liselotdewachter.bsky.social
Streptococcus pneumoniae cell biology at UCLouvain & de Duve Institute, Brussels, Belgium
Reposted by Liselot Dewachter
Great turnout today at the KNVM Fundamental Microbiology section Fall Meeting in Groningen, with keynote lectures from @bramkamplab.bsky.social and @liselotdewachter.bsky.social. Now on to drinks!
November 6, 2025 at 3:59 PM
Great turnout today at the KNVM Fundamental Microbiology section Fall Meeting in Groningen, with keynote lectures from @bramkamplab.bsky.social and @liselotdewachter.bsky.social. Now on to drinks!
Reposted by Liselot Dewachter
📝New preprint! #MicroSky
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle
The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...
www.biorxiv.org
September 25, 2025 at 7:12 AM
📝New preprint! #MicroSky
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.
🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.
www.biorxiv.org/content/10.1...
There's so much more than just the peptidoglycan that protects bacteria from lysis 👀🦠🧪
Super interesting paper!
Super interesting paper!
#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.
Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.
📄 www.nature.com/articles/s41...
Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology
Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.
www.nature.com
August 12, 2025 at 3:12 PM
There's so much more than just the peptidoglycan that protects bacteria from lysis 👀🦠🧪
Super interesting paper!
Super interesting paper!
The DMF department at the University of Lausanne, Switzerland is an amazing place to be! Highly recommend!
New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM
wwwfbm.unil.ch
June 11, 2025 at 4:11 PM
The DMF department at the University of Lausanne, Switzerland is an amazing place to be! Highly recommend!
Job alert 🦠🧪: We are looking for a postdoc (and PhD candidate!) to join our team at UCLouvain/de Duve institute in Brussels, Belgium. You will work on our ERC Starting Grant project aimed at characterizing cell cycle regulation in S. pneumoniae. More information here: dewachterlab.com/join-us/.
May 5, 2025 at 12:56 PM
Job alert 🦠🧪: We are looking for a postdoc (and PhD candidate!) to join our team at UCLouvain/de Duve institute in Brussels, Belgium. You will work on our ERC Starting Grant project aimed at characterizing cell cycle regulation in S. pneumoniae. More information here: dewachterlab.com/join-us/.
Throwback to this beautiful video of S. pneumoniae dying because they don't have enough Und-P, the carrier that transports cell envelope building blocks from cytoplasm to extracellular space. RIP pneumo! 🪦🦠
March 24, 2025 at 6:55 PM
Throwback to this beautiful video of S. pneumoniae dying because they don't have enough Und-P, the carrier that transports cell envelope building blocks from cytoplasm to extracellular space. RIP pneumo! 🪦🦠
When you have (1) a lab, and (2) a friend who is really into his new 3D printer, this is what you get: pokemon falcon tube holders 🤩🧪🦠
March 11, 2025 at 10:22 AM
When you have (1) a lab, and (2) a friend who is really into his new 3D printer, this is what you get: pokemon falcon tube holders 🤩🧪🦠
Reposted by Liselot Dewachter
Proud to present our latest model of aggregation-induced dormancy, published in #NatureComms @liselotdewachter.bsky.social
rdcu.be/d7EcI
rdcu.be/d7EcI
Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery
Nature Communications - Recalcitrant infections are often caused by dormant bacteria, including persisters and viable but nonculturable cells. Here, the authors explore how composition and...
rdcu.be
January 27, 2025 at 10:46 AM
Proud to present our latest model of aggregation-induced dormancy, published in #NatureComms @liselotdewachter.bsky.social
rdcu.be/d7EcI
rdcu.be/d7EcI
Reposted by Liselot Dewachter
🔬 New research by @michielslab.bsky.social @liselotdewachter.bsky.social @vibmicrobes.bsky.social in @naturecomms.bsky.social shows how protein 'clumps' drive bacteria into a state of dormancy, with implications for antibiotic resistance. ➡️ Read here vibbio.tech/40Qxc2M
🙌 FWO Vlaanderen - KU Leuven
🙌 FWO Vlaanderen - KU Leuven
January 28, 2025 at 9:25 AM
🔬 New research by @michielslab.bsky.social @liselotdewachter.bsky.social @vibmicrobes.bsky.social in @naturecomms.bsky.social shows how protein 'clumps' drive bacteria into a state of dormancy, with implications for antibiotic resistance. ➡️ Read here vibbio.tech/40Qxc2M
🙌 FWO Vlaanderen - KU Leuven
🙌 FWO Vlaanderen - KU Leuven
Reposted by Liselot Dewachter
Our department is recruiting a tenure-track Assistant Professor on microbial interactions linked to the
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!
December 5, 2023 at 4:32 PM
Our department is recruiting a tenure-track Assistant Professor on microbial interactions linked to the
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!