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Reposted by Liselot Dewachter

Géraldine Laloux @lalouxlab.bsky.social · 14d

📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...

Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle

The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...

www.biorxiv.org

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Liselot Dewachter @liselotdewachter.bsky.social · Aug 12

There's so much more than just the peptidoglycan that protects bacteria from lysis 👀🦠🧪
Super interesting paper!

Michael Deghelt @michaeldeghelt.bsky.social · Jul 29

#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.

Our study shows that the periplasm — enclosed by OM–PG connections — acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.

📄 www.nature.com/articles/s41...

Peptidoglycan–outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology

Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.

www.nature.com

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Liselot Dewachter @liselotdewachter.bsky.social · Jun 11

The DMF department at the University of Lausanne, Switzerland is an amazing place to be! Highly recommend!

Jan-Willem Veening @veeninglab.com · Jun 10

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM

wwwfbm.unil.ch

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Liselot Dewachter @liselotdewachter.bsky.social · May 5

Job alert 🦠🧪: We are looking for a postdoc (and PhD candidate!) to join our team at UCLouvain/de Duve institute in Brussels, Belgium. You will work on our ERC Starting Grant project aimed at characterizing cell cycle regulation in S. pneumoniae. More information here: dewachterlab.com/join-us/.

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Liselot Dewachter @liselotdewachter.bsky.social · Mar 24

Throwback to this beautiful video of S. pneumoniae dying because they don't have enough Und-P, the carrier that transports cell envelope building blocks from cytoplasm to extracellular space. RIP pneumo! 🪦🦠

STCmicrobeblog @stcmicrobeblog.bsky.social · Mar 24

schaechter.asmblog.org/schaechter/2...
#MicroSky

Lost & Found #5

by Christoph — When you leave 𝕏, it means that among the “bookmarks” you take with you, you will also come across some that contain images or videos that are mainly nice to look at and even entertaini...

schaechter.asmblog.org

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Liselot Dewachter @liselotdewachter.bsky.social · Mar 24

Impressive, Renske! Matching microscopy phenotypes to the correct scientist is next level nerd alert, I love it! 😂 And indeed, these beautiful dying cells were mine. Great to see them popping up again!

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Liselot Dewachter @liselotdewachter.bsky.social · Mar 11

When you have (1) a lab, and (2) a friend who is really into his new 3D printer, this is what you get: pokemon falcon tube holders 🤩🧪🦠

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Reposted by Liselot Dewachter

Jan Michiels lab @michielslab.bsky.social · Jan 27

Proud to present our latest model of aggregation-induced dormancy, published in #NatureComms @liselotdewachter.bsky.social

rdcu.be/d7EcI

Composition and liquid-to-solid maturation of protein aggregates contribute to bacterial dormancy development and recovery

Nature Communications - Recalcitrant infections are often caused by dormant bacteria, including persisters and viable but nonculturable cells. Here, the authors explore how composition and...

rdcu.be

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Reposted by Liselot Dewachter

VIB @viblifesciences.bsky.social · Jan 28

🔬 New research by @michielslab.bsky.social @liselotdewachter.bsky.social @vibmicrobes.bsky.social in @naturecomms.bsky.social shows how protein 'clumps' drive bacteria into a state of dormancy, with implications for antibiotic resistance. ➡️ Read here vibbio.tech/40Qxc2M
🙌 FWO Vlaanderen - KU Leuven

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Reposted by Liselot Dewachter

Sara Mitri @saramitri.bsky.social · Dec 5

Our department is recruiting a tenure-track Assistant Professor on microbial interactions linked to the
NCCR Microbiomes nccr-microbiomes.ch Don't miss this opportunity to join a friendly, dynamic department in a city with hard-to-beat quality of life. Apply tinyurl.com/4k2mevax by Jan 31!

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Liselot Dewachter @liselotdewachter.bsky.social · Nov 11

Ready, Strep, Go! Thanks for the strains 😊

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