Lothar Kalmbach
@lkalmbach.bsky.social
780 followers 250 following 26 posts
🌱 Assistant Professor at Uni of Neuchatel 🇨🇭 Investigating plant cell walls, vasculature, and physiology.
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lkalmbach.bsky.social
… still worth listening to - if you speak German.
Reposted by Lothar Kalmbach
hueihsuantsai.bsky.social
Very excited to see our @nikogeldner.bsky.social lab x Feng Zhou lab work featured on the cover of Science!
(1/5) We reveal how root architecture and nutrient leakage shape spatial patterns of microbial colonization, moving beyond traditional models of uniform exudation.
science.org
Using precise spatial and temporal analysis, researchers in Science provide insight into how bacteria around the root interact both with the plant and with each other.

Learn more in this week's issue: https://scim.ag/3WgNajk
A confocal microscopy image shows root-colonizing bacteria clustering around an emerging lateral root, where localized glutamine leakage induces spatially confined reporter activity.
lkalmbach.bsky.social
Congratulations Merissa! Such an exciting story!!
Reposted by Lothar Kalmbach
zoenahas.bsky.social
Happy to share slightly late that the main work of my PhD is now published! How do plants regulate the number + location of growing branches 🌳🌲? We used experiments and mathematical modelling to study how local and systemic signals are integrated during shoot branching regulation. A thread:
plosbiology.org
How do #plants dynamically modulate their shoot branching for optimal returns? ‪@zoenahas.bsky.social‬ &co show that BRC1 modulates bud competitiveness by reducing #auxin efflux, integrating hormonal cues to fine-tune branching patterns @plosbiology.org @slcuplants.bsky.social 🧪 plos.io/4pnrwY2
2-node explants capture key properties of bud regulation. Top left: A stem segment with two axillary buds illustrates two regulatory hubs controlling shoot branching (i) local expression of the transcription factor BRC1, a repressor of bud activation, and (ii) systemic regulation of the auxin transport network. A canalization-based model of shoot branching postulates that bud activation requires the establishment of canalized auxin transport from the bud into the main stem, the dynamics of which is influenced by autocatalytic feedback in auxin flow between the bud and the stem, and the relative auxin source and sink strengths of the bud and stem, respectively. The relationship between BRC1- and auxin-transport-mediated regulation is not known. Bottom left: Arabidopsis bud activation occurs in at least two phases: a slow-growing lag phase, then a switch to rapid outgrowth. Typical timescale 10–12 days. Right: Diagram illustrating the four possible growth outcomes for bud activation on 2-node explants, and their representation in a Mitchison plot. Mitchison plots present the length of the top bud versus that of the bottom bud over time in each explant. Explants where at least one bud grows are termed active, otherwise, they are inactive. Within active explants, there are three possible outcomes: both buds grow, or only either the top or the bottom bud activates.
lkalmbach.bsky.social
News on PILS & ERAD! Big congrats to @seinabnoura.bsky.social @kleinevehnlab.bsky.social and colleagues!
kleinevehnlab.bsky.social
1/ 🌱 When plants face stress, they often suppress growth to save resources.
In our new Science Advances paper, we reveal how: plants repurpose their ER quality control machinery (ERAD) to regulate auxin compartmentalization and thus growth.
www.science.org/doi/10.1126/...
ERAD machinery controls the conditional turnover of PIN-LIKES in plants
Plant ERAD machinery governs the turnover of auxin transporters involved in developmental and stress responses.
www.science.org
lkalmbach.bsky.social
Congratulations! Exciting news! Many years ago I was a student there! Lots of fond memories. I’m looking forward to what’s coming from your group in the years to come!
Reposted by Lothar Kalmbach
nikogeldner.bsky.social
Call for a tenure-track position at our Department of Plant Molecular Biology in Lausanne! We are searching for promising early-career researchers in the broad field of plant-organismal interactions. Deadline: November 30, 2025 - Please re-post!

career5.successfactors.eu/career?caree...
Career Opportunities: DBMV: Tenure Track Assistant Professor towards Associate Professor in the field of Plant-organism (22484)
career5.successfactors.eu
lkalmbach.bsky.social
Such great news! Congratulations!
Reposted by Lothar Kalmbach
tonnigrubeandersen.bsky.social
Six years ago, I started at the MPIPZ with a head full of ideas. What a journey. I’m thrilled to share that, from Jan 2026, I will be moving to Zurich as a chaired associate professor at the University of Zurich.
A new chapter, and plenty of roots still to grow. Can’t wait for the adventure ahead!
Reposted by Lothar Kalmbach
martinpacesa.bsky.social
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, Christian, @sokrypton.org, Bruno and many other amazing lab members and collaborators.

www.nature.com/articles/s41...
Reposted by Lothar Kalmbach
rodrigoreislab.com
My lab's very first manuscripts are out!!!!

- We identified nearly 60 conserved RNA structures in plastids #chloroplast #RNA
- We found that transcriptional response to warm temperatures in whole seedling is confounded by response at organ level #thermomorphogenesis

Link to both preprints below
lkalmbach.bsky.social
Congratulations, Rodrigo! 🎉🍾
Reposted by Lothar Kalmbach
mplantpcom.bsky.social
Oligosaccharide Elicitors in Plant Immunity: Molecular Mechanisms and Disease Resistance Strategies #review #PlantCommunications cell.com/plant-commun...
Reposted by Lothar Kalmbach
mariebarberon.bsky.social
Very excited that our work on directional symplastic transport in differentiated root is now published!A developmental switch controls cell-to-cell transport in roots via pectin-linked plasmodesmata changes: Molecular Plant www.cell.com/molecular-pl...
lkalmbach.bsky.social
Paper 🚨!!
Plasmodesmata transport first in both, then only in one direction in roots! Congratulations to Lea and @mariebarberon.bsky.social !!
mplantpcom.bsky.social
A developmental switch controls cell-to-cell transport in roots via pectin-linked plasmodesmata changes #research #MolecularPlant cell.com/molecular-pl...
Reposted by Lothar Kalmbach
kleinevehnlab.bsky.social
🧵1/
New preprint out!
We reveal that ERAD, a protein degradation pathway, selectively targets intracellular PILS auxin transport facilitators to control growth.
This expands ERAD's role beyond protein quality control, right into developmental regulation.
www.biorxiv.org/content/10.1...
Reposted by Lothar Kalmbach
martinalegris.bsky.social
🔥Postdoc opportunity 🌱

The Legris lab at the University of Neuchâtel 🇨🇭 is looking for a Postdoc to work on the regulation of branching by warm temperatures. If you have a background on plant physiology and development, and you're interested in shoot thermomorphogenesis, apply now!
Reposted by Lothar Kalmbach
catsteam.bsky.social
📣 Join us for the 3rd Carbon Allocation in Plants Workshop 🇨🌿

🗓️ Oct 27–29, 2025

📍 INRAE Versailles – @ijpb-versaillescly.bsky.social

🌱 Explore carbon flow in plants with top researchers!

🔗 Register: bit.ly/4kYzzrT ⏳ 10th of August

ℹ️ Info: bit.ly/43HpN5P

🙏 Thanks to all partners 👇 see below