Maria Christophorou
@mariachristophorou.bsky.social
Group leader in #Epigenetics. Fascinated by how stem cells work and how our genes make us. Can’t wait to find out what #citrullination is all about. She/her.
Pinned
The KRAB-Zinc Finger protein ZKSCAN3 represses enhancers via embedded retrotransposons
Gene cis -regulatory sequences are increasingly recognised as containing “domesticated” transposable elements that impact their function. The KRAB Zinc Finger Protein (KZFP) family of transcription fa...
www.biorxiv.org
Our new #preprint has:
✅ A KRAB Zinc Finger (the SCAN domain-containing kind)
✅ #transposon sequences (the SINE kind)
✅ #epigenetic regulation (the #enhancer kind)
✅ lineage specification (the neural kind)
❌ and NO heterochromatin!
All by PhD student Daniel Moore 🚀
www.biorxiv.org/content/10.1...
✅ A KRAB Zinc Finger (the SCAN domain-containing kind)
✅ #transposon sequences (the SINE kind)
✅ #epigenetic regulation (the #enhancer kind)
✅ lineage specification (the neural kind)
❌ and NO heterochromatin!
All by PhD student Daniel Moore 🚀
www.biorxiv.org/content/10.1...
Reposted by Maria Christophorou
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
tinyurl.com
September 19, 2025 at 10:53 AM
🔬We have a fully funded Cambridge Biosciences DTP PhD postion to study #Proteostasis and #Aging in colloboration with @jrkumita.bsky.social @Pharmacology. Details on the project ▶️https://tinyurl.com/2zhkjjhs + bbsrcdtp.lifesci.cam.ac.uk/how-apply . Please RT.
Reposted by Maria Christophorou
🥳Well deserved recognition of achievements and impacts across the Institute and internationally for Simon Andrews @babraham-bioinf.bsky.social who wins a #PapinPrizes for Contributions to Research!
#HETS2025 #PapinPrizes
Contribution to Research Award
Congratulations to Simon Andrews @babrahaminst.bsky.social
Contribution to Research Award
Congratulations to Simon Andrews @babrahaminst.bsky.social
July 9, 2025 at 4:37 PM
🥳Well deserved recognition of achievements and impacts across the Institute and internationally for Simon Andrews @babraham-bioinf.bsky.social who wins a #PapinPrizes for Contributions to Research!
Reposted by Maria Christophorou
The Chromatin And Development lab are hiring a postdoc!
Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!
lms.mrc.ac.uk/work/vacanci...
Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!
lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences
The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...
lms.mrc.ac.uk
June 26, 2025 at 3:19 PM
The Chromatin And Development lab are hiring a postdoc!
Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!
lms.mrc.ac.uk/work/vacanci...
Come join us; we are a happy and hard working team @mrc-lms.bsky.social in London UK. Projects span the intersection of chromatin and transposon biology in dev't and disease. Email/DM for more info. Pls RT!
lms.mrc.ac.uk/work/vacanci...
Reposted by Maria Christophorou
#JobAlert! We have an opening for a postdoctoral scientist in #CancerMetabolism in my lab @mrc-lms.bsky.social. If you're interested in the role of metabolism in drug response and resistance in cancer, and would like to work in a fun and friendly team, check it out: lms.mrc.ac.uk/work/vacanci...
MRC Postdoctoral Research Scientist - MRC Laboratory of Medical Sciences
The MRC Laboratory of Medical Sciences (LMS) is a biomedical research institute where scientists and clinicians collaborate to advance the understanding of biology and its application to medicine. LMS...
lms.mrc.ac.uk
June 25, 2025 at 8:57 AM
#JobAlert! We have an opening for a postdoctoral scientist in #CancerMetabolism in my lab @mrc-lms.bsky.social. If you're interested in the role of metabolism in drug response and resistance in cancer, and would like to work in a fun and friendly team, check it out: lms.mrc.ac.uk/work/vacanci...
Reposted by Maria Christophorou
👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab!
👉 deadline 20/06
👇 check it out
www.godinholab.com
👉 deadline 20/06
👇 check it out
www.godinholab.com
June 3, 2025 at 8:57 AM
👋 Are you looking for a postdoc position? Do you think microtubules are fascinating? Then we might have the job for you! 2-year funded postdoc to join our lab!
👉 deadline 20/06
👇 check it out
www.godinholab.com
👉 deadline 20/06
👇 check it out
www.godinholab.com
Congratulations Stefan and all, great to see this beautiful work out!
Delighted & excited to share our latest preprint on non-canonical enhancers in human pluripotent stem cells, the result of a fantastic and fun collaboration with @guenesdoganlab.bsky.social:
www.biorxiv.org/content/10.1...
🧵 below
www.biorxiv.org/content/10.1...
🧵 below
Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells
Enhancers are key gene regulatory elements that ensure the precise spatiotemporal execution of developmental gene expression programmes. However recent findings indicate that approaches to identify en...
www.biorxiv.org
June 3, 2025 at 8:24 AM
Congratulations Stefan and all, great to see this beautiful work out!
Reposted by Maria Christophorou
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/
www.jobs.cam.ac.uk/job/51488/
Research Assistant / Research Associate (Fixed Term) - Job Opportunities - University of Cambridge
Research Assistant / Research Associate (Fixed Term) in the Department of Plant Sciences at the University of Cambridge.
www.jobs.cam.ac.uk
May 30, 2025 at 12:13 PM
A three year postdoctoral position is available in my group, investigating plant centromere structure, function and evolution @camplantsci.bsky.social
www.jobs.cam.ac.uk/job/51488/
www.jobs.cam.ac.uk/job/51488/
Reposted by Maria Christophorou
🫀Job alert 🧬 come and be our colleague! Join a BBSRC-funded consortium aiming to understand how the human heart develops - you will be contributing multimodal single cell & spatial transcriptomics data using zebrafish and human cardiac organoids as models. Learn more: www.heartdevelopment.org (1/4)
CellTalk HHD | Human Heart Development Research
CellTalk-Human Heart Development is a BBSRC funded consortium established to find out more about how cells come together to build the heart as it grows inside the womb.
www.heartdevelopment.org
May 16, 2025 at 10:10 AM
🫀Job alert 🧬 come and be our colleague! Join a BBSRC-funded consortium aiming to understand how the human heart develops - you will be contributing multimodal single cell & spatial transcriptomics data using zebrafish and human cardiac organoids as models. Learn more: www.heartdevelopment.org (1/4)
Reposted by Maria Christophorou
Ahead of our celebratory symposium on 1-2 May to mark Len Stephen's and Phill Hawkins’s pioneering contributions to the PI3K signalling field, you might enjoy this feature with Len and Phill reflecting on their decades-long friendship, partnership – and fishing.
www.babraham.ac.uk/blog/2021/11...
www.babraham.ac.uk/blog/2021/11...
April 29, 2025 at 11:37 AM
Ahead of our celebratory symposium on 1-2 May to mark Len Stephen's and Phill Hawkins’s pioneering contributions to the PI3K signalling field, you might enjoy this feature with Len and Phill reflecting on their decades-long friendship, partnership – and fishing.
www.babraham.ac.uk/blog/2021/11...
www.babraham.ac.uk/blog/2021/11...
Reposted by Maria Christophorou
Funded PhD Studentship available in my lab at @lsiexeter.bsky.social.
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
Opportunity for LSI PHD studentship – starting in September 2025 or January 2026 PhD Studentship applications will open on 1st...
lsi.exeter.ac.uk
April 12, 2025 at 12:58 PM
Funded PhD Studentship available in my lab at @lsiexeter.bsky.social.
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Want to study how chromatin remodellers act on enhancers to facilitate cell fate decisions in human pluripotent cells? Want to work and live in a lively city by the sea? Get in touch/Apply!
lsi.exeter.ac.uk/groups/hendr...
Reposted by Maria Christophorou
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
April 22, 2025 at 5:24 PM
Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency
Reposted by Maria Christophorou
🔥 Open postdoc position in human inflammation-driven control of infection! 🔥
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)
Please share!
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)
Please share!
April 13, 2025 at 3:58 PM
🔥 Open postdoc position in human inflammation-driven control of infection! 🔥
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)
Please share!
Join me at the University of Geneva, Switzerland this summer as I’m moving my Wellcome-funded research activity to the Department of Microbiology and Molecular Medicine! (1/5)
Please share!
Reposted by Maria Christophorou
Do you have transposon-related research cooking, with some cool results you are exciting to share? Start thinking about registering to #EMBOMobileGenome workshop! Nov 4-7 2025 in Heidelberg. One of the historical TE meetings, with a diverse and welcoming community. www.embl.org/about/info/c...
1/3
1/3
The mobile genome: genetic and physiological impacts of transposable elements
www.embl.org
April 2, 2025 at 6:30 PM
Do you have transposon-related research cooking, with some cool results you are exciting to share? Start thinking about registering to #EMBOMobileGenome workshop! Nov 4-7 2025 in Heidelberg. One of the historical TE meetings, with a diverse and welcoming community. www.embl.org/about/info/c...
1/3
1/3
Reposted by Maria Christophorou
Fully funded (at UK home rate) #PhD studentships to start 2025/2026 at University of Exeter, UK. #Chromatin #StemCells #Signalling #ProteinStructure #LineageCommitment #Transcription
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Hendrich Group - Starting Sept 2025 - Living Systems Institute - University of Exeter
LSI PHD studentship – start September 2025 or January 2026 Project 1: Title of Project: Control of chromatin remodeller activity...
lsi.exeter.ac.uk
March 29, 2025 at 8:11 AM
Fully funded (at UK home rate) #PhD studentships to start 2025/2026 at University of Exeter, UK. #Chromatin #StemCells #Signalling #ProteinStructure #LineageCommitment #Transcription
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Please spread the word, and anyone interested please contact me.
lsi.exeter.ac.uk/groups/hendr...
Reposted by Maria Christophorou
Deadline for abstract submission & registration approaching (April 1st)
The time is now!!!!
#EvoDevoTempo ⌛️⏳
The time is now!!!!
#EvoDevoTempo ⌛️⏳
Join us in Paris in May 6-9 for an exciting EMBO Workshop on Developmental timing mechanisms and evolution. Slots still open for short talks - Registration deadline next [email protected] @trayon.bsky.social @mdiazcuadros.bsky.social
meetings.embo.org/event/25-dev...
meetings.embo.org/event/25-dev...
Developmental timing across species: From mechanisms to evolutionary insights
Like choreography, development consists of a highly ordered suite of steps and transitions. Modifying developmental tempo can affect final size and composition of tissues, as well as their plasticity…
meetings.embo.org
March 25, 2025 at 9:03 PM
Deadline for abstract submission & registration approaching (April 1st)
The time is now!!!!
#EvoDevoTempo ⌛️⏳
The time is now!!!!
#EvoDevoTempo ⌛️⏳
We are grateful to the BBSRC and Babraham
Research Campus for a Campus Innovation Award, allowing us to explore the translational potential of our research.
Very excited to be working with Axol Bioscience Ltd. @axolbio.bsky.social on this!
Research Campus for a Campus Innovation Award, allowing us to explore the translational potential of our research.
Very excited to be working with Axol Bioscience Ltd. @axolbio.bsky.social on this!
NEWS | Excited to share that the @mariachristophorou.bsky.social lab and Axol Bioscience are joining forces! By combining expertise in epigenetics and cell biology with cutting-edge #StemCell technology the project will explore innovative approaches to faster and more efficient cell reprogramming.
New partnership looks to improve cell reprogramming methods for healthcare benefits | Babraham Institute
www.babraham.ac.uk
March 20, 2025 at 5:26 PM
We are grateful to the BBSRC and Babraham
Research Campus for a Campus Innovation Award, allowing us to explore the translational potential of our research.
Very excited to be working with Axol Bioscience Ltd. @axolbio.bsky.social on this!
Research Campus for a Campus Innovation Award, allowing us to explore the translational potential of our research.
Very excited to be working with Axol Bioscience Ltd. @axolbio.bsky.social on this!
Join us to celebrate the careers and scientific contributions of our amazing colleagues and lipid signalling legends, Len Stephens and Phill Hawkins on May 1-2 at The Bahraham Institute
@babrahaminst.bsky.social
@babrahaminst.bsky.social
Join us at the Institute on 1st & 2nd May for our Signalling Symposium to celebrate Phill Hawkins and Len Stephens.
🧪 Sessions on #proteostasis, #PI3K, #autophagy, #redox biology and #nuclear signalling.
www.eventbrite.co.uk/e/cellular-s...
🧪 Sessions on #proteostasis, #PI3K, #autophagy, #redox biology and #nuclear signalling.
www.eventbrite.co.uk/e/cellular-s...
Cellular signals for health & disease
A symposium marking the contributions of Len Stephens and Phillip Hawkins
www.eventbrite.co.uk
March 20, 2025 at 5:09 PM
Join us to celebrate the careers and scientific contributions of our amazing colleagues and lipid signalling legends, Len Stephens and Phill Hawkins on May 1-2 at The Bahraham Institute
@babrahaminst.bsky.social
@babrahaminst.bsky.social
Reposted by Maria Christophorou
Submitted a paper review for a journal (can you guess which?) on Tuesday evening. Well within my expertise, was happy to do it.
On Wednesday morning there were 3 (THREE) review requests from the same journal.
This comes to mind (Fig.1 slays me every time)
www.scs.stanford.edu/~dm/home/pap...
On Wednesday morning there were 3 (THREE) review requests from the same journal.
This comes to mind (Fig.1 slays me every time)
www.scs.stanford.edu/~dm/home/pap...
March 20, 2025 at 9:32 AM
Submitted a paper review for a journal (can you guess which?) on Tuesday evening. Well within my expertise, was happy to do it.
On Wednesday morning there were 3 (THREE) review requests from the same journal.
This comes to mind (Fig.1 slays me every time)
www.scs.stanford.edu/~dm/home/pap...
On Wednesday morning there were 3 (THREE) review requests from the same journal.
This comes to mind (Fig.1 slays me every time)
www.scs.stanford.edu/~dm/home/pap...
Reposted by Maria Christophorou
Please help spread the word about funding for undergraduate summer research in the UK in the field of gene and cell therapy, made possible by the generous support of BSGCT. Potential supervisors can apply for this funding by 4th April. Details at: www.bsgct.org/undergraduates
March 1, 2025 at 12:30 PM
Please help spread the word about funding for undergraduate summer research in the UK in the field of gene and cell therapy, made possible by the generous support of BSGCT. Potential supervisors can apply for this funding by 4th April. Details at: www.bsgct.org/undergraduates
Reposted by Maria Christophorou
My group at Cambridge is seeking an experienced and motivated new member to help ensure the smooth operation of our work on obesity and neurodegenerative disease. Please circulate if you think folks in your network might be interested. Details at: www.jobs.cam.ac.uk/job/50479/
March 1, 2025 at 12:35 PM
My group at Cambridge is seeking an experienced and motivated new member to help ensure the smooth operation of our work on obesity and neurodegenerative disease. Please circulate if you think folks in your network might be interested. Details at: www.jobs.cam.ac.uk/job/50479/
Reposted by Maria Christophorou
Enthusiastic post-doc sought to investigate how experience shapes the brain. Wellcome Trust funded. Ideal for fly-person with expertise in behaviour. Internatiinal lab, at beautiful University of Birmingham capmus, EDI, lively city, UK. Application deadline 19 March.
#post-doc
#Drosophila
#post-doc
#Drosophila
February 23, 2025 at 9:44 AM
Enthusiastic post-doc sought to investigate how experience shapes the brain. Wellcome Trust funded. Ideal for fly-person with expertise in behaviour. Internatiinal lab, at beautiful University of Birmingham capmus, EDI, lively city, UK. Application deadline 19 March.
#post-doc
#Drosophila
#post-doc
#Drosophila
I am a super #ProudPI for our brilliant student Daniel Moore, who knocked his PhD viva out of the park!
Thank you to his examiners, Rob Illingworth and
@florianmerkle.bsky.social for the great discussions.
You can check out some of Daniel's thesis work here:
www.biorxiv.org/content/10.1...
Thank you to his examiners, Rob Illingworth and
@florianmerkle.bsky.social for the great discussions.
You can check out some of Daniel's thesis work here:
www.biorxiv.org/content/10.1...
February 17, 2025 at 12:46 PM
I am a super #ProudPI for our brilliant student Daniel Moore, who knocked his PhD viva out of the park!
Thank you to his examiners, Rob Illingworth and
@florianmerkle.bsky.social for the great discussions.
You can check out some of Daniel's thesis work here:
www.biorxiv.org/content/10.1...
Thank you to his examiners, Rob Illingworth and
@florianmerkle.bsky.social for the great discussions.
You can check out some of Daniel's thesis work here:
www.biorxiv.org/content/10.1...
Thank you for the invitation to present some of our work and for the stimulating questions!
Great start of our #ChemBio workshop with a fantastic talk from @mariachristophorou.bsky.social from @babrahaminst.bsky.social on citrullination modulators.
February 14, 2025 at 3:58 PM
Thank you for the invitation to present some of our work and for the stimulating questions!
Reposted by Maria Christophorou
Calling all students. The registration for the European Summer School on Stem Cell Biology and Regenerative Medicine is now open.
February 11, 2025 at 10:53 PM
Calling all students. The registration for the European Summer School on Stem Cell Biology and Regenerative Medicine is now open.