Marissa Scavuzzo she/her
@marissascavuzzo.bsky.social
Assistant Professor CWRUSOM in the Institute for Glial Sciences & HHMI Hanna Gray Faculty Fellow | Scientific Director at Rise Up | open science, equity, innovation
scavuzzolab.org
riseupnortheastohio.org
scavuzzolab.org
riseupnortheastohio.org
Reposted by Marissa Scavuzzo she/her
Belated post… last year, our lab painted a glia mural!
It took about 1 day and we used a projector for tracing.
Can you guess which cell is which?
It took about 1 day and we used a projector for tracing.
Can you guess which cell is which?
January 30, 2026 at 10:23 PM
Belated post… last year, our lab painted a glia mural!
It took about 1 day and we used a projector for tracing.
Can you guess which cell is which?
It took about 1 day and we used a projector for tracing.
Can you guess which cell is which?
Reposted by Marissa Scavuzzo she/her
Pain-sensing neurons in the intestines play an important role in defending the body from threats.
New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.
🔗 https://go.nature.com/4jTvO7k
New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.
🔗 https://go.nature.com/4jTvO7k
January 29, 2026 at 5:55 PM
Pain-sensing neurons in the intestines play an important role in defending the body from threats.
New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.
🔗 https://go.nature.com/4jTvO7k
New study led by the Artis Lab at @weillcornell.bsky.social shows TRPV1+ nociceptors in the gut activate tuft cells, leading to expulsion of parasites.
🔗 https://go.nature.com/4jTvO7k
When the hats meet: scientist, mom, community educator
January 23, 2026 at 3:22 AM
When the hats meet: scientist, mom, community educator
Reposted by Marissa Scavuzzo she/her
Driven by an experience familiar to many — watching parents age — HHMI Hanna Gray Fellow Melanie McReynolds wants to answer a fundamental question: How can we age healthier? The key may lie in better understanding NAD+ & how its levels decline as we grow older. Via @asbmb.bsky.social: bit.ly/45tDuHB
January 18, 2026 at 4:26 PM
Driven by an experience familiar to many — watching parents age — HHMI Hanna Gray Fellow Melanie McReynolds wants to answer a fundamental question: How can we age healthier? The key may lie in better understanding NAD+ & how its levels decline as we grow older. Via @asbmb.bsky.social: bit.ly/45tDuHB
Reposted by Marissa Scavuzzo she/her
Join us on 30 January as three rising stars— Jie Zheng, @marissascavuzzo.bsky.social and @drnancypadilla.bsky.social—sit down with @franciscorr25.bsky.social for a conversation exploring where the field of neuroscience is headed and how their work is helping to drive it forward.
#neuroskyence
#neuroskyence
🧠 Some of science’s greatest unanswered questions center around the human brain. Join us on 1/30 for free Presents event: “Shaping the Future of Neuroscience,” featuring three of @thetransmitter.bsky.social Rising Stars. https://www.simonsfoundation.org/event/shaping-the-future-of-neuroscience/
Shaping the Future of Neuroscience
Shaping the Future of Neuroscience on Simons Foundation
www.simonsfoundation.org
January 9, 2026 at 6:45 PM
Join us on 30 January as three rising stars— Jie Zheng, @marissascavuzzo.bsky.social and @drnancypadilla.bsky.social—sit down with @franciscorr25.bsky.social for a conversation exploring where the field of neuroscience is headed and how their work is helping to drive it forward.
#neuroskyence
#neuroskyence
Reposted by Marissa Scavuzzo she/her
Thrilled to start my lab at the @whiteheadinstitute.bsky.social @mit.edu and to join such a special community of creative and inspiring colleagues. The Sullivan Lab asks (1) how and (2) why infections make us sick, bridging immunology and neuroscience to understand host defense at the organism scale
“I want everyone in my lab to be exposed to many ways of thinking about biology,” says Whitehead Institute’s newest Member, immunologist Zuri Sullivan. “Creative science often comes from making connections across systems, and Whitehead is uniquely well-suited for that.”
shorturl.at/EFsmh
shorturl.at/EFsmh
January 6, 2026 at 2:08 PM
Thrilled to start my lab at the @whiteheadinstitute.bsky.social @mit.edu and to join such a special community of creative and inspiring colleagues. The Sullivan Lab asks (1) how and (2) why infections make us sick, bridging immunology and neuroscience to understand host defense at the organism scale
Clearing some adult gut tissues. It is very, very gross and it smells terrible and I’m very excited about it
January 5, 2026 at 6:18 PM
Clearing some adult gut tissues. It is very, very gross and it smells terrible and I’m very excited about it
Reposted by Marissa Scavuzzo she/her
Being an American feels like getting on a school bus and then your bus driver decides to do a drive by
January 3, 2026 at 2:02 PM
Being an American feels like getting on a school bus and then your bus driver decides to do a drive by
Reposted by Marissa Scavuzzo she/her
It's bittersweet to describe the success of #NIHPREP Scholars. You are awesome #scientists. Don't let anyone tell you otherwise. www.biorxiv.org/content/10.6...
PREP-aring is worth it: Success of the Case Western Reserve University Post-baccalaureate Research Education Program and its Scholars
The Post-baccalaureate Research Education Program (PREP), established by the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health in 2000, was a research-intense...
www.biorxiv.org
January 3, 2026 at 2:02 PM
It's bittersweet to describe the success of #NIHPREP Scholars. You are awesome #scientists. Don't let anyone tell you otherwise. www.biorxiv.org/content/10.6...
Grateful for a new year filled with discovery, imagination, and community. No walls in sight
January 2, 2026 at 5:22 PM
Grateful for a new year filled with discovery, imagination, and community. No walls in sight
Reposted by Marissa Scavuzzo she/her
🎄✨ Getting into the holiday spirit? Why not add a little Pi to your plans! 🥧🏃♀️
Give yourself (or someone else!) a reason to stay active after the holidays by signing up for the 2026 Rise Up: Pi Race!
Give yourself (or someone else!) a reason to stay active after the holidays by signing up for the 2026 Rise Up: Pi Race!
December 23, 2025 at 9:20 PM
🎄✨ Getting into the holiday spirit? Why not add a little Pi to your plans! 🥧🏃♀️
Give yourself (or someone else!) a reason to stay active after the holidays by signing up for the 2026 Rise Up: Pi Race!
Give yourself (or someone else!) a reason to stay active after the holidays by signing up for the 2026 Rise Up: Pi Race!
Reposted by Marissa Scavuzzo she/her
*First preprint from our lab* !!!!!
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️
December 15, 2025 at 6:26 PM
*First preprint from our lab* !!!!!
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️
How does the brain learn to anchor its internal sense of direction to the outside world? 🧭
led by Mark Plitt @markplitt.bsky.social & Dan Turner-Evans, w/ Vivek Jayaraman:
“Octopamine instructs head direction plasticity” www.biorxiv.org/content/10.6...
Thread ⬇️
Reposted by Marissa Scavuzzo she/her
"We find that while TAD boundaries pair more frequently than non-boundary regions, these interactions are infrequent and are uncorrelated with transcriptional activity of genes within the TAD. (...) These results suggest that TAD boundary architecture and gene activity are largely uncoupled"
TAD boundary architecture and gene activity are uncoupled
Topologically associating domains (TADs) are prominent features of genome organization. A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD...
www.biorxiv.org
December 18, 2025 at 11:43 AM
"We find that while TAD boundaries pair more frequently than non-boundary regions, these interactions are infrequent and are uncorrelated with transcriptional activity of genes within the TAD. (...) These results suggest that TAD boundary architecture and gene activity are largely uncoupled"
Go @cobarnes27.bsky.social and team!!!!
#YearInReview @cobarnes27.bsky.social, @adonisrubio.bsky.social & team have designed a series of dual or “bispecific” antibodies, called CoV2-biRN, which could potentially resist the ever-evolving SARS-CoV-2 virus as well as other coronaviruses in the future: news.stanford.edu/stories/2025...
New antibodies show potential to neutralize virus that causes COVID-19
A Stanford-led team has found two antibodies that can work together to defeat all SARS-CoV-2 variants. More research is needed, but the approach could help in the development of treatments to keep…
news.stanford.edu
December 18, 2025 at 2:10 PM
Go @cobarnes27.bsky.social and team!!!!
Reposted by Marissa Scavuzzo she/her
"there's a new serif in town"
Marco Rubio ordered diplomats to return to using Times New Roman font in official communications, calling his predecessor's decision to adopt Calibri a “wasteful” diversity move
Rubio Stages Font Coup: Times New Roman Ousts Calibri
The secretary of state called it a "wasteful" diversity move, according to an internal department cable seen by Reuters.
www.huffpost.com
December 10, 2025 at 1:06 AM
"there's a new serif in town"
Reposted by Marissa Scavuzzo she/her
PDAC is a terrible malady and needs new inroads. We integrate a cell atlas, develop 3D tumoroid models, and map phenotypic spaces at scale. Very cool data inside! www.biorxiv.org/content/10.1..., www.biorxiv.org/content/10.1...
December 4, 2025 at 10:32 PM
PDAC is a terrible malady and needs new inroads. We integrate a cell atlas, develop 3D tumoroid models, and map phenotypic spaces at scale. Very cool data inside! www.biorxiv.org/content/10.1..., www.biorxiv.org/content/10.1...
This paper is blowing my mind www.nature.com/articles/s42...
Fat sensory cues in early life program central response to food and obesity - Nature Metabolism
Non-nutritive sensory components of high-fat diet, such as bacon flavour, are sufficient to impair metabolic health in offspring in mice.
www.nature.com
December 4, 2025 at 3:37 AM
This paper is blowing my mind www.nature.com/articles/s42...
Reposted by Marissa Scavuzzo she/her
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage controlling type 1 and 2 immune balance @natimmunol.nature.com @champalimaudf.bsky.social @neuroimmune-rok.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 25, 2025 at 8:36 PM
Enteric nervous system-derived VIP restrains differentiation of LGR5+ stem cells toward the secretory lineage controlling type 1 and 2 immune balance @natimmunol.nature.com @champalimaudf.bsky.social @neuroimmune-rok.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Teaching a class tomorrow in a subject I have never actually taken a class in
November 30, 2025 at 3:41 PM
Teaching a class tomorrow in a subject I have never actually taken a class in
Reposted by Marissa Scavuzzo she/her
Harvard gets its research funding back through defiance and lawsuits.
Majority of Harvard’s Research Funding Has Been Restored
As of Tuesday, Harvard University had recouped most of the federal research funding it lost when the Trump administration froze its access to grants earlier this year, multiple local news organization...
www.insidehighered.com
November 29, 2025 at 4:31 AM
Harvard gets its research funding back through defiance and lawsuits.
Reposted by Marissa Scavuzzo she/her
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Properties and functions of transcriptionally distinct enteric neurons
Developing genetic access to transcriptionally distinct enteric neurons in vivo enables
the examination of morphological heterogeneity across cell types as well as cell-type-specific
influences on GI ...
www.cell.com
November 26, 2025 at 11:15 AM
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Reposted by Marissa Scavuzzo she/her
Is staying active, supporting your community, and having fun in your plans for 2026??
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
November 25, 2025 at 4:11 PM
Is staying active, supporting your community, and having fun in your plans for 2026??
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
Reposted by Marissa Scavuzzo she/her
Imagine, if you will, that NASA updated its website to suggest gravity might not exist, prompting CalTech and CERN to release statements saying, "With great sadness, we can no longer recommend listening to NASA."
This is what's happening in epidemiology.
This is what's happening in epidemiology.
November 21, 2025 at 8:58 PM
Imagine, if you will, that NASA updated its website to suggest gravity might not exist, prompting CalTech and CERN to release statements saying, "With great sadness, we can no longer recommend listening to NASA."
This is what's happening in epidemiology.
This is what's happening in epidemiology.
Reposted by Marissa Scavuzzo she/her
@hhmi.org Summer Undergraduate Research Experience - #CechFellows named in honor of Prof Tom Cech
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
www.hhmi.org
November 22, 2025 at 4:15 PM
@hhmi.org Summer Undergraduate Research Experience - #CechFellows named in honor of Prof Tom Cech
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...