Marissa Scavuzzo she/her
@marissascavuzzo.bsky.social
Assistant Professor CWRUSOM in the Institute for Glial Sciences & HHMI Hanna Gray Faculty Fellow | Scientific Director at Rise Up | open science, equity, innovation
scavuzzolab.org
riseupnortheastohio.org
scavuzzolab.org
riseupnortheastohio.org
Pinned
Unpicking the Mystery of the Body’s ‘Second Brain’
Sitting alongside the neurons in your enteric nervous system are underappreciated glial cells, which play key roles in digestion and disease that scientists are only just starting to understand.
www.wired.com
Read a bit about our science here:
scavuzzolab.org/research/
In WIRED magazine:
www.wired.com/story/gut-se...
In Science magazine:
www.science.org/doi/10.1126/...
scavuzzolab.org/research/
In WIRED magazine:
www.wired.com/story/gut-se...
In Science magazine:
www.science.org/doi/10.1126/...
Reposted by Marissa Scavuzzo she/her
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Properties and functions of transcriptionally distinct enteric neurons
Developing genetic access to transcriptionally distinct enteric neurons in vivo enables
the examination of morphological heterogeneity across cell types as well as cell-type-specific
influences on GI ...
www.cell.com
November 26, 2025 at 11:15 AM
More detailed functional interrogation of enteric neuron subpopulations www.cell.com/cell/abstrac...
Reposted by Marissa Scavuzzo she/her
Is staying active, supporting your community, and having fun in your plans for 2026??
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
November 25, 2025 at 4:11 PM
Is staying active, supporting your community, and having fun in your plans for 2026??
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
If so, mark your calendars for the 3rd annual Rise Up: Pi Race on March 14th, 2026!
Reposted by Marissa Scavuzzo she/her
Imagine, if you will, that NASA updated its website to suggest gravity might not exist, prompting CalTech and CERN to release statements saying, "With great sadness, we can no longer recommend listening to NASA."
This is what's happening in epidemiology.
This is what's happening in epidemiology.
November 21, 2025 at 8:58 PM
Imagine, if you will, that NASA updated its website to suggest gravity might not exist, prompting CalTech and CERN to release statements saying, "With great sadness, we can no longer recommend listening to NASA."
This is what's happening in epidemiology.
This is what's happening in epidemiology.
Reposted by Marissa Scavuzzo she/her
@hhmi.org Summer Undergraduate Research Experience - #CechFellows named in honor of Prof Tom Cech
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Summer Undergraduate Research Experience | HHMI
The Cech Fellows Program is a paid, nine-week summer research experience empowering the next generation of scientific leaders.
www.hhmi.org
November 22, 2025 at 4:15 PM
@hhmi.org Summer Undergraduate Research Experience - #CechFellows named in honor of Prof Tom Cech
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
Deadline to apply: 12/22/2025
Spend 9 weeks in a paid, mentored biomedical research experience in an HHMI lab. See you next summer!!!
www.hhmi.org/programs/cec...
What an honor to be recognized as one of @thetransmitter.bsky.social Rising Stars of Neuroscience 2025!
Check out this year's award winners and their contributions to
neuroscience at www.thetransmitter.org/early-career...
Check out this year's award winners and their contributions to
neuroscience at www.thetransmitter.org/early-career...
November 15, 2025 at 3:31 PM
What an honor to be recognized as one of @thetransmitter.bsky.social Rising Stars of Neuroscience 2025!
Check out this year's award winners and their contributions to
neuroscience at www.thetransmitter.org/early-career...
Check out this year's award winners and their contributions to
neuroscience at www.thetransmitter.org/early-career...
My brilliant 4 year old daughter did not realize it but she painted the myenteric plexus, submucosal plexus, and mucosal glia
November 14, 2025 at 8:18 PM
My brilliant 4 year old daughter did not realize it but she painted the myenteric plexus, submucosal plexus, and mucosal glia
Reposted by Marissa Scavuzzo she/her
And here is the story after peer review. This work highlights our current approach, which is to use Piezo channels to uncover new areas of biology that are shaped by mechanical forces: www.science.org/doi/10.1126/...
November 13, 2025 at 10:05 PM
And here is the story after peer review. This work highlights our current approach, which is to use Piezo channels to uncover new areas of biology that are shaped by mechanical forces: www.science.org/doi/10.1126/...
What if inflammation doesn’t just bring in immune cells, but changes the entire neighborhood?
Our new preprint led by brilliant MD/PhD student @kateletai.bsky.social in collaboration with the Cominelli lab and @biancaislam.bsky.social explores this question:
www.biorxiv.org/content/10.1...
Our new preprint led by brilliant MD/PhD student @kateletai.bsky.social in collaboration with the Cominelli lab and @biancaislam.bsky.social explores this question:
www.biorxiv.org/content/10.1...
Epithelial and stromal remodeling in murine Crohn’s disease-like ileitis
Background and Aims Inflammatory bowel disease is characterized by progressive epithelial, immune, and stromal dysfunction. Human datasets yield important insights yet are inherently descriptive, requ...
www.biorxiv.org
November 13, 2025 at 1:53 AM
What if inflammation doesn’t just bring in immune cells, but changes the entire neighborhood?
Our new preprint led by brilliant MD/PhD student @kateletai.bsky.social in collaboration with the Cominelli lab and @biancaislam.bsky.social explores this question:
www.biorxiv.org/content/10.1...
Our new preprint led by brilliant MD/PhD student @kateletai.bsky.social in collaboration with the Cominelli lab and @biancaislam.bsky.social explores this question:
www.biorxiv.org/content/10.1...
People might not realize - this wasn’t just one problematic person. He was (and is) influential. And this has real consequences.
“Female scientists who have kids can’t be taken seriously” and many other jabs at women have been directly said to me, within the last decade, by other scientists.
“Female scientists who have kids can’t be taken seriously” and many other jabs at women have been directly said to me, within the last decade, by other scientists.
I read this book when I was 15 and fell in love with DNA. I re-read it at 32 with lived experience in Science and it filled me with rage. I cannot pick up that book now. It reveals what women were/are up against.
Based on his self-described behavior in The Double Helix and these actions it is easy and appropriate to write him off as an ignorant jerk.
38/41
38/41
November 8, 2025 at 6:02 PM
People might not realize - this wasn’t just one problematic person. He was (and is) influential. And this has real consequences.
“Female scientists who have kids can’t be taken seriously” and many other jabs at women have been directly said to me, within the last decade, by other scientists.
“Female scientists who have kids can’t be taken seriously” and many other jabs at women have been directly said to me, within the last decade, by other scientists.
THIS WEEKEND!
Register to hear from me and two of my lab members!
We will talk about:
-our journey in science
-what we study in the lab
-the importance of investing in science
-how supporting international scholars and scientists from diverse backgrounds benefits everyone
Register to hear from me and two of my lab members!
We will talk about:
-our journey in science
-what we study in the lab
-the importance of investing in science
-how supporting international scholars and scientists from diverse backgrounds benefits everyone
Next weekend, members of our lab are hosting a Teach-In! Open to everyone, in person and virtual.
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
November 7, 2025 at 4:38 PM
THIS WEEKEND!
Register to hear from me and two of my lab members!
We will talk about:
-our journey in science
-what we study in the lab
-the importance of investing in science
-how supporting international scholars and scientists from diverse backgrounds benefits everyone
Register to hear from me and two of my lab members!
We will talk about:
-our journey in science
-what we study in the lab
-the importance of investing in science
-how supporting international scholars and scientists from diverse backgrounds benefits everyone
Reposted by Marissa Scavuzzo she/her
One analytical model shows that, as of November 5th, the dismantling of U.S.A.I.D. has already caused the deaths of 600,000 people, two-thirds of them children. https://newyorkermag.visitlink.me/jUzNSc
The Shutdown of U.S.A.I.D. Has Already Killed Hundreds of Thousands
The short documentary “Rovina’s Choice” tells the story of what goes when aid goes.
newyorkermag.visitlink.me
November 6, 2025 at 9:00 PM
One analytical model shows that, as of November 5th, the dismantling of U.S.A.I.D. has already caused the deaths of 600,000 people, two-thirds of them children. https://newyorkermag.visitlink.me/jUzNSc
Reposted by Marissa Scavuzzo she/her
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 5:48 PM
The Leading Edge Fellows gathered this week to celebrate Zara Weinberg, a beloved member of our community. Our 7th cohort of Leading Edge Fellows (2026) will be named in her honor.
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
The Zara Weinberg Leading Edge Cohort application is now open! Due Feb 2.
www.leadingedgesymposium.org/apply/
November 5, 2025 at 10:15 PM
The Allen Institute is a premier scientific powerhouse that upholds values - open science, team science, and collaboration - that promote the progress of science rather than individual advancement. Past NGLs are leaders in their fields. To be a part of this group is a huge honor!
The Next Generation Leaders program at the Allen Institute recognizes and supports emerging and diverse early career researchers in bioscience. alleninstitute.org/news/allen-i...
Allen Institute announces 2025 Next Generation Leaders
Fostering collaboration and innovation from emerging leaders in bioscience
alleninstitute.org
November 4, 2025 at 10:20 PM
The Allen Institute is a premier scientific powerhouse that upholds values - open science, team science, and collaboration - that promote the progress of science rather than individual advancement. Past NGLs are leaders in their fields. To be a part of this group is a huge honor!
Reposted by Marissa Scavuzzo she/her
Meet our 2025 cohort of Next Generation Leaders! For the next 3 years, they will network with other rising stars, participate in professional development, and share their ideas for future research directions.
November 4, 2025 at 4:25 PM
Meet our 2025 cohort of Next Generation Leaders! For the next 3 years, they will network with other rising stars, participate in professional development, and share their ideas for future research directions.
I shouldn’t have to share this. I’m so sad and angry at what the American healthcare system forces people to go through
My uncle is in critical condition and stuck in an out-of-network ICU. Please share, donate, and VOTE TOMORROW. It is one small way to push for something better gofund.me/9d9648949
My uncle is in critical condition and stuck in an out-of-network ICU. Please share, donate, and VOTE TOMORROW. It is one small way to push for something better gofund.me/9d9648949
November 3, 2025 at 10:18 PM
I shouldn’t have to share this. I’m so sad and angry at what the American healthcare system forces people to go through
My uncle is in critical condition and stuck in an out-of-network ICU. Please share, donate, and VOTE TOMORROW. It is one small way to push for something better gofund.me/9d9648949
My uncle is in critical condition and stuck in an out-of-network ICU. Please share, donate, and VOTE TOMORROW. It is one small way to push for something better gofund.me/9d9648949
Reposted by Marissa Scavuzzo she/her
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
November 1, 2025 at 6:37 PM
👉 We generated a starter pack for #neurogastroenterology and enteric #neuroscience!
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Let's connect and bring gut-brain research and clinical neurogastroenterology to the next level! 🌐
go.bsky.app/3Z82PbH
Next weekend, members of our lab are hosting a Teach-In! Open to everyone, in person and virtual.
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
November 3, 2025 at 1:15 AM
Next weekend, members of our lab are hosting a Teach-In! Open to everyone, in person and virtual.
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
Come learn about the brain inside your gut and what happens when misinformation and defunding threaten research
Reposted by Marissa Scavuzzo she/her
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
October 31, 2025 at 8:45 AM
Paul Nurse describing the main job of a PI
(From ‘The Thinking Game’, 2024)
(From ‘The Thinking Game’, 2024)
boo
from the @glialsciences.bsky.social 2nd annual Halloween rager
congrats to @kateletai.bsky.social for winning the spooky data contest with some truly frightening datasets and to Yuka for winning the costume contest as the cutest grinch in town (sorry @tesarlab.bsky.social)
from the @glialsciences.bsky.social 2nd annual Halloween rager
congrats to @kateletai.bsky.social for winning the spooky data contest with some truly frightening datasets and to Yuka for winning the costume contest as the cutest grinch in town (sorry @tesarlab.bsky.social)
October 31, 2025 at 2:02 PM
boo
from the @glialsciences.bsky.social 2nd annual Halloween rager
congrats to @kateletai.bsky.social for winning the spooky data contest with some truly frightening datasets and to Yuka for winning the costume contest as the cutest grinch in town (sorry @tesarlab.bsky.social)
from the @glialsciences.bsky.social 2nd annual Halloween rager
congrats to @kateletai.bsky.social for winning the spooky data contest with some truly frightening datasets and to Yuka for winning the costume contest as the cutest grinch in town (sorry @tesarlab.bsky.social)
Reposted by Marissa Scavuzzo she/her
Tissue and cellular spatiotemporal dynamics in colon aging - @nygenome.org @flatironinstitute.org @broadinstitute.org @cancerdynamics.bsky.social go.nature.com/47I1RBF
Tissue and cellular spatiotemporal dynamics in colon aging - Nature Biotechnology
cSplotch compares spatial transcriptomics data across ages and regions of mouse colon tissue.
go.nature.com
October 22, 2025 at 2:45 PM
Tissue and cellular spatiotemporal dynamics in colon aging - @nygenome.org @flatironinstitute.org @broadinstitute.org @cancerdynamics.bsky.social go.nature.com/47I1RBF
Reposted by Marissa Scavuzzo she/her
Keynote alert! Lorenz Studer, MD (MSKCC), will speak at #TGS2025 on Nov 4 at the Sheila and Eric Samson Pavilion, Health Ed Campus of CWRU & Cleveland Clinic.
🔗 Learn more and register for free:
case.edu/medicine/gli...
🔗 Learn more and register for free:
case.edu/medicine/gli...
October 20, 2025 at 6:25 PM
Keynote alert! Lorenz Studer, MD (MSKCC), will speak at #TGS2025 on Nov 4 at the Sheila and Eric Samson Pavilion, Health Ed Campus of CWRU & Cleveland Clinic.
🔗 Learn more and register for free:
case.edu/medicine/gli...
🔗 Learn more and register for free:
case.edu/medicine/gli...
Fall in Cleveland 🍁
October 20, 2025 at 1:59 PM
Fall in Cleveland 🍁
Reposted by Marissa Scavuzzo she/her
#postdoc position in #Toulouse, #France to decipher cellular and microenvironment alterations in #IBD using patient-derived #organoid and #fibroblasts cultures in human-based #gut-on-chip. Still some days to apply. Don't wait!
#inserm #cnrs #cea #organ-on-chip #stemcells #ooc
#inserm #cnrs #cea #organ-on-chip #stemcells #ooc
🔬 Postdoctoral Opportunity in Biomedical Research. #Organoids & #Organs-on-Chip for #IBD and #Personalized #Medicine at #i2mc in #Toulouse, #France at the crossroads of #stem cell biology, #microphysiological systems, and translational medicine.
👉 Apply before Nov. 1rst at [email protected]
👉 Apply before Nov. 1rst at [email protected]
October 19, 2025 at 8:26 PM
#postdoc position in #Toulouse, #France to decipher cellular and microenvironment alterations in #IBD using patient-derived #organoid and #fibroblasts cultures in human-based #gut-on-chip. Still some days to apply. Don't wait!
#inserm #cnrs #cea #organ-on-chip #stemcells #ooc
#inserm #cnrs #cea #organ-on-chip #stemcells #ooc