Lightnews — Scholar-powered news

Adele Marston @marstonlab.bsky.social · Jul 7

Really looking forward to this meeting, still chance to register!

DivIDE conference @divide-conference.bsky.social · Jul 6

Last chance to register for the 3rd DivIDE conference in sunny Barcelona @crg.eu!

🚨With 20+ selected talks and travel grants for three outstanding junior scientists a great opportunity for young researchers!

🔗 Learn more & register: www.divide-conference.com
📅 Registration Deadline: July 13, 2025

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Adele Marston @marstonlab.bsky.social · Mar 7

The Discovery Research Platform for Hidden Cell Biology now has a Bluesky account. Follow us here for news and events @drphcb-uoe.bsky.social

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Adele Marston @marstonlab.bsky.social · Feb 28

Last day for early bird registration!

Adele Marston @marstonlab.bsky.social · Feb 6

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

Wendy Bickmore @wbickmor.bsky.social · Nov 12

Interested in difficult to access parts of genetics, cellular & structural biology? Join us in Edinburgh 2-4th April 2025 for "Hidden Cell, Dark Genome"
Regulation in the dark genome
Uncharted proteins, RNA complexity
Atomic structures at cellular scale
Cell diversity
www.ed.ac.uk/c/hidden-cel...

Adele Marston @marstonlab.bsky.social · Feb 26

A special thanks to the fly expert reviewers for helping us clarify a few points, including the late Scott Hawley, whose review was filled with the enthusiasm and generosity we all knew him for.

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Adele Marston @marstonlab.bsky.social · Feb 26

@lbkoch9.bsky.social and I wrote a Current Opinion piece highlighting recent progress in our understanding of centromere and kinetochore function in meiosis.
www.sciencedirect.com/science/arti...

The functional organisation of the centromere and kinetochore during meiosis

Meiosis generates gametes through a specialised cell cycle that reduces the genome by half. Homologous chromosomes are segregated in meiosis I and sis…

www.sciencedirect.com

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Adele Marston @marstonlab.bsky.social · Feb 26

Early bird registration is this Friday - don’t miss it!

Adele Marston @marstonlab.bsky.social · Feb 6

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

Wendy Bickmore @wbickmor.bsky.social · Nov 12

Interested in difficult to access parts of genetics, cellular & structural biology? Join us in Edinburgh 2-4th April 2025 for "Hidden Cell, Dark Genome"
Regulation in the dark genome
Uncharted proteins, RNA complexity
Atomic structures at cellular scale
Cell diversity
www.ed.ac.uk/c/hidden-cel...

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Reposted by Adele Marston

Hannah Long @hannahlong.bsky.social · Feb 21

📣 One week left for early bird registration and abstract submission for the 'Hidden Cell, Dark Genome' conference 3-4th April in Edinburgh. Regulatory functions of the dark genome, uncharted proteins & RNA complexity, cellular diversity, and atomic structures at the cellular scale 🧬! Join us #HCDG25

Hidden cell dark genome 2025

institute-genetics-cancer.ed.ac.uk

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Adele Marston @marstonlab.bsky.social · Feb 6

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

Wendy Bickmore @wbickmor.bsky.social · Nov 12

Interested in difficult to access parts of genetics, cellular & structural biology? Join us in Edinburgh 2-4th April 2025 for "Hidden Cell, Dark Genome"
Regulation in the dark genome
Uncharted proteins, RNA complexity
Atomic structures at cellular scale
Cell diversity
www.ed.ac.uk/c/hidden-cel...

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Adele Marston @marstonlab.bsky.social · Jan 31

I am very shocked and saddened to hear this news. He made so many important contributions in so many different ways.

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Reposted by Adele Marston

HunterLab.bsky.social @hunterlab.bsky.social · Jan 15

📢The 2025 MAYosis webinar series will be held on consecutive Wednesdays, May 7-28, at 4 pm CET (7 am PST; 12 am JST) meiosis.cornell.edu/mayoss2025/ Apply to give a talk (deadline is March 8, trainees and junior faculty only): tinyurl.com/47k3cjpn Registration is free: tinyurl.com/39rs53yv

MAYosis 2025

meiosis.cornell.edu

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Adele Marston @marstonlab.bsky.social · Dec 18

See also related work by @eecutts.bsky.social and thanks to Erin and Luis for a great co-submission experience www.embopress.org/doi/full/10....

Molecular mechanism of condensin I activation by KIF4A | The EMBO Journal

imageimageHow loss of KIF4A chromokinesin reduces chromosome association of condensin has remained unclear. This study demonstrates that human condensin I is auto-inhibited by short linear motifs (SLi...

www.embopress.org

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Adele Marston @marstonlab.bsky.social · Dec 18

Happy to see this out before the end of the year. Fantastic work by Lily Wang with help from our wonderful technologists in the Discovery Platform Proteomics Core managed by Christos Spanos. Great publishing experience @embojournal.bsky.social www.embopress.org/doi/full/10....

Molecular mechanism targeting condensin for chromosome condensation | The EMBO Journal

imageimageHow the condensin complex is recruited to genomic domains to promote their condensation is incompletely understood. This study identifies a generalised molecular mechanism by which condensin...

www.embopress.org

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Reposted by Adele Marston

Binyam Mogessie ቢንያም ሞገሴ @binyammogessie.bsky.social · Nov 29

Chromosome segregation errors are common in the early stages of human embryonic development. Read here our open access commentary on three recent studies of spindle architecture and positioning features that
could provide insights into why early embryos are predisposed to aneuploidy.
rdcu.be/d1TgG

On the origin of mitosis-derived human embryo aneuploidy

Nature Communications - Chromosome segregation errors are common in the early stages of human embryonic development. By examining the first mitotic divisions of human embryos using live cell...

rdcu.be

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Reposted by Adele Marston

Katja Wassmann @meiosis-mom.bsky.social · Nov 29

Looking forward to the next cell cycle meeting at the Salk Institute! www.salk.edu/events/scien...

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Reposted by Adele Marston

Aga Gambus @agagambus.bsky.social · Nov 27

Two fully funded PhD opportunities in our lab. Interdisciplinary, DNA replication, cancer research, structural biology… deadlines in early Jan. Open to international students. t.co/WEJJIU4zU4

www.findaphd.com/phds/project...

https://www.findaphd.com/phds/project/inhibitor-of-donson-gins-interaction-as-an-experimental-tool-and-potential-anticancer-strategy/?p178853

t.co

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Reposted by Adele Marston

Mcclelland lab @mcclellandlab.bsky.social · Nov 14

Announcing the next EMBO Chromosome Segregation and Aneuploidy Meeting! Italy 2025. Please register and join us for another exciting and friendly meeting in a beautiful location meetings.embo.org/event/25-ane...

Chromosome Segregation and Aneuploidy

Aneuploidy is a hallmark of cancer and developmental disorders such as Down syndrome. Understanding how cells accomplish faithful chromosome segregation and how chromosomal instability (CIN) impacts …

meetings.embo.org

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Adele Marston @marstonlab.bsky.social · Nov 17

Great line up for EMBO meiosis 2025!

Takashi Akera Lab @takashiakeralab.bsky.social · Nov 14

Official website for EMBO meiosis 2025 is live now! Looking forward to seeing you in Switzerland next June! #meiosis4eva

meetings.embo.org/event/25-mei...

Meiosis: Exploring diversity to discover the fundamentals

Meiosis is an essential cell division for sexual reproduction and fertility across eukaryotes. It involves a series of tightly regulated processes, including entry into meiosis, pairing of homologs, …

meetings.embo.org

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Reposted by Adele Marston

Urszula McClurg @urszulamcclurg.bsky.social · Nov 9

#Meiosis4eva starter pack. I am sure I missed many so please self nominate by commenting or just DMing me go.bsky.app/P3BJYze

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Adele Marston @marstonlab.bsky.social · Feb 12

Want to know how the abundance or phosphorylation of your favourite budding yeast protein changes during meiosis? Check out our new searchable online tool created by the talented Lori Koch meiphosprot.bio.ed.ac.uk. Also check out the preprint www.biorxiv.org/content/10.1... coming to @emboj soon!

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Adele Marston @marstonlab.bsky.social · Jan 22

9 days left to register for the Cell Cycle meeting in Roscoff. Register and abstract submission here: www.insb.cnrs.fr/fr/cycling-d...

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Reposted by Adele Marston

Bungo Akiyoshi @bungoakiyoshi.bsky.social · Jan 5

A new preprint from our group in collaboration with @jvhooff.bsky.social and @eelcotromer.bsky.social. We discovered that trypanosomes have (a zombie of) Bub1-Bub3 despite the fact that tryps do not have a canonical spindle checkpoint! This is a team work involving Dan, WillC, Midori and Patryk

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · Jan 5

Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins https://www.biorxiv.org/content/10.1101/2024.01.04.574194v1

Faithful transmission of genetic material is crucial for the survival of all organisms. In many euka

www.biorxiv.org

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Adele Marston @marstonlab.bsky.social · Jan 6

Overall we show that Mad3 acts outside of its checkpoint role to actively direct chromosome segregation.

Adele Marston @marstonlab.bsky.social · Jan 6

We found that Mad3 binds the Stu1 (CLASP) microtubule regulator through its degenerate TOGL1 domain. We showed that Mad3-Stu1 association rescues the segregation of chromosomes that lack crossovers or fail to biorient in meiosis I.

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Adele Marston @marstonlab.bsky.social · Jan 6

We discovered that in addition to its well known role in delaying the cell cycle as part of the spindle checkpoint, Mad3, has a separate role in promoting chromosome alignment on the spindle in budding yeast meiosis.

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Adele Marston @marstonlab.bsky.social · Jan 4

Check out our new preprint. Great PhD work of Anu Mukherjee with expert mass spec from Christos Spanos. Checkpoint-independent association of Mad3BUBR1 with Stu1CLASP directs homolog alignment in meiosis I www.biorxiv.org/content/10.1...

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