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Reposted by Takashi Akera Lab

Mark Peifer (He, him) @peiferlabunc.bsky.social · 2d

Faculty positions in animal morphogenesis that may be filled at the Assistant or Associate Professor level in one of my favorite Departments" Cell and Systems Biology at the University of Toronto. 1/n
jobs.utoronto.ca/job/Toronto-...
jobs.utoronto.ca/job/Toronto-...

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Aga Gambus @agagambus.bsky.social · 2d

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

Senior Research Technician at University of Birmingham

Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

www.jobs.ac.uk

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Science News @scinews.bsky.social · 3d

The 2025 #NobelPrize in Physiology or Medicine has been awarded to Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi “for their discoveries concerning peripheral immune tolerance.”

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NPR @npr.org · 3d

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

The medicine Nobel Prize goes to 3 scientists for work on peripheral immune tolerance

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were honored for research into how the body helps the immune system avoid attacking your own tissues instead of foreign invaders.

n.pr

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Katrina Velle @katrinavelle.bsky.social · 4d

PhD or Master's position available for Fall 2026!

Interested in how actin drives cell crawling, eating, dividing, or osmoregulation? What about pathogenesis of a brain-eating amoeba? Or eukaryotic evolution? If so, apply through my website: katrinavelle.wixsite.com/science/cont...
Please share!

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Takashi Akera Lab @takashiakeralab.bsky.social · 4d

Congrats Mia and Mike🎉 Great paper for journal club!

Mia Levine @levine-lab.bsky.social · 5d

Check out this new Levine-Lampson collaboration, led by the talented Hyuk-Joon Jeon.

We explored the consequences of inheriting long telomeres from dad and short telomeres from mom. Or the reciprocal. Turns out, parent-of-origin matters (in mice, at least).

authors.elsevier.com/c/1loW-3QW8S...

authors.elsevier.com

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Reposted by Takashi Akera Lab

Erin Green @erinrgreen.bsky.social · 4d

Job alert ‼️ UChicago Micro is hiring! Open to tenured/tenure track faculty at all levels in any area of microbiology. Come join our amazing and growing department. apply.interfolio.com/174404

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Mark Peifer (He, him) @peiferlabunc.bsky.social · 7d

The remarkable number of people, me included, who were inspired by her work, life and example is the biggest tribute. Find a way to honor her memory. The wolrd is a bit smaller and sadder with her gone

The Guardian @theguardian.com · 7d

Jane Goodall, world-renowned primatologist, dies aged 91

Jane Goodall Institute says ‘tireless advocate’ for natural world died in California during US speaking tour The world-renowned primatologist Jane Goodall has died at the age of 91, her institute has said. The Jane Goodall Institute announced that she had passed away of natural causes while in California as part of a US speaking tour. Continue reading...

www.theguardian.com

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Aurora Ruiz-Herrera @aruizherrera.bsky.social · 7d

🚨 New from our lab in #ScienceAdvances!

RAD21L cohesin acts as both a 3D genome architect and a transcriptional gatekeeper in the male germline. Its loss disrupts both structure and function—highlighting the tight link between genome folding and gene regulation

www.science.org/doi/10.1126/...

Meiotic cohesin RAD21L shapes 3D genome structure and transcription in the male germline

Deletion of the meiotic subunit RAD21L alters 3D chromatin structure and transcription in the mammalian male germ line.

www.science.org

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Takashi Akera Lab @takashiakeralab.bsky.social · 7d

Congrats on the great work!!🥳

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Reposted by Takashi Akera Lab

Kate Cavanaugh @katecavanaugh.bsky.social · 7d

See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...

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Reposted by Takashi Akera Lab

Annika Barber @annikabarber.bsky.social · 7d

Despite These Times...my department is hiring! I really like my department, we have a good mix of disciplines and organisms and we're really low-drama. We also get pizza at faculty meeting. So if you're a computational and structural biologist, join us! 🧪 jobs.rutgers.edu/postings/260...

Assistant Professor - Tenure Track Faculty

The Department of Molecular Biology and Biochemistry at Rutgers, The State University of New Jersey, is inviting applicants for a tenure-track Assistant Professor position. The position requires a doc...

jobs.rutgers.edu

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Dr. Lucky Tran @luckytran.com · 7d

"If we lose hope, we're doomed."

We must continue Dr. Jane Goodall's mission and all fight for the future of the planet.

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NPR @npr.org · 7d

JUST IN: Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

Jane Goodall, legendary primatologist, has died at age 91

Jane Goodall, primatologist who transformed our understanding of the lives of apes, has died, according to an announcement from the Jane Goodall Institute.

n.pr

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Johanna Joyce @johannajoyce.bsky.social · 7d

Dr. Jane Goodall, 1934-2025

An exceptional scientist, and a singular woman in science

#WomeninScience 🐒

www.nytimes.com/2025/10/01/o...

Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91

www.nytimes.com

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Takashi Akera Lab @takashiakeralab.bsky.social · 8d

Huge congrats, Chloe!!🎉

Chloe Girard, PhD @chloegirard.bsky.social · 8d

🚨 First pre-print from my team !!

TL;DR: presence of polymorphism (sequence differences between the homologous chromosomes) can *increase* the local rate of recombination in Arabidopsis thaliana, turning cold regions of the genome hot (purple v. grey) !

The recombination frequency (cM/Mb) along chromosome 4 of A. thaliana (female meiosis).

In full hybrids (grey), where polymorphism is distributed all along chromosomes, most crossovers occur in the regions surrounding the Centromere (Cen), and very few at chromosome ends (Tel: telomeres).

In lines where polymorphism is restricted to chromosome ends (purple), the local recombination rate increases drastically, at the expense of the non-polymorphic regions (yellow).

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Sara Wickstrom @sarawickstrom.bsky.social · 10d

How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇

Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology

McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.

www.nature.com

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Boris Sieber @borissieber.bsky.social · 14d

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!

Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1

doi.org/10.1101/2025...

Schematic of MAPK signalling in fission yeast, budding yeast and Metazoa. No MAPK scaffold was known for ERK-like MAPK in fission yeast, as opposed to budding yeast Ste5 and metazoan KSR1/2.

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Sophie G Martin @sophiemartinlab.bsky.social · 13d

Super excited that this story by @borissieber.bsky.social is now on BioRxiv!

For decades, we thought there was no MAPK scaffold for the ERK-like cascade that promotes sexual reproduction in fission yeast ... until Boris found it !

See the thread 👇 and enjoy the paper!

doi.org/10.1101/2025...

Boris Sieber @borissieber.bsky.social · 14d

Mammalian cells have KSR, budding yeast has Ste5… and fission yeast has Sms1 as the MAPK scaffold for sexual reproduction!

Very excited to share my postdoc work where we discover that the hemi-arrestin Sms1 binds all components of the MAPK cascade, including ERK-like Spk1

doi.org/10.1101/2025...

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Takashi Akera Lab @takashiakeralab.bsky.social · 14d

Congrats Jen, Adam, and the team!!🎉🥂Love this work.

Adam Phillippy @aphillippy.bsky.social · 14d

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3]
📺 youtu.be/JmlY5omxQVc
📄 www.nature.com/articles/s41...

How Stowers Scientists Found the DNA Site Where Robertsonian Chromosomes Fuse

YouTube video by Stowers Institute for Medical Research

youtu.be

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Reposted by Takashi Akera Lab

Adam Phillippy @aphillippy.bsky.social · 14d

🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3]
📺 youtu.be/JmlY5omxQVc
📄 www.nature.com/articles/s41...

How Stowers Scientists Found the DNA Site Where Robertsonian Chromosomes Fuse

YouTube video by Stowers Institute for Medical Research

youtu.be

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Reposted by Takashi Akera Lab

Chrystal Starbird @drstarbird.bsky.social · 15d

Know rising stars in biological, medicinal, or pharmaceutical chemistry? Nominate them for a feature. Link to a blog post and the nomination form below!

axial.acs.org/biology-and-...

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Dmitri Petrov @petrovadmitri.bsky.social · Jun 3

Flybase lost all of the NIH support overnight - it is a disaster for the community. Please consider donating. I just did! www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

www.philanthropy.cam.ac.uk

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Andres Bendesky @bendeskylab.com · 19d

Tenure-track Assistant Professor in Computational Ecology and/or Evolution @columbiauniversity.bsky.social.
Deadline to apply September 30.
Reach out if you have questions.

apply.interfolio.com/172496

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Reposted by Takashi Akera Lab

bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 17d

Linking Germline Telomere Removal to Global Programmed DNA Elimination in Tetrahymena Genome Differentiation https://www.biorxiv.org/content/10.1101/2025.09.21.677574v1

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