Max Renner
@maxrenner.bsky.social
PI at Umeå University and UCMR | Northern Sweden | Alum: @ox.ac.uk | Structural Virology | https://renner-lab.com/ | 🇸🇪 🦠🔬 🌱
Reposted by Max Renner
🎉 New paper from the Dept. of Medical Biochemistry and Biophysics!
Congrats to Noopur Singh et al. on their @narjournal.bsky.social publication showing that DNA polymerase ε interacts with PCNA in vivo to support efficient leading-strand DNA replication 🧬
👉 academic.oup.com/nar/article/...
Congrats to Noopur Singh et al. on their @narjournal.bsky.social publication showing that DNA polymerase ε interacts with PCNA in vivo to support efficient leading-strand DNA replication 🧬
👉 academic.oup.com/nar/article/...
January 16, 2026 at 8:39 AM
🎉 New paper from the Dept. of Medical Biochemistry and Biophysics!
Congrats to Noopur Singh et al. on their @narjournal.bsky.social publication showing that DNA polymerase ε interacts with PCNA in vivo to support efficient leading-strand DNA replication 🧬
👉 academic.oup.com/nar/article/...
Congrats to Noopur Singh et al. on their @narjournal.bsky.social publication showing that DNA polymerase ε interacts with PCNA in vivo to support efficient leading-strand DNA replication 🧬
👉 academic.oup.com/nar/article/...
Reposted by Max Renner
January 15, 2026 at 7:25 AM
Reposted by Max Renner
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...
🧪🧠Cell www.cell.com/cell/fulltex...
Anoctamin-2-specific T cells link Epstein-Barr virus to multiple sclerosis
Researchers identified anoctamin-2 (ANO2) as a frequent autoimmune target in multiple
sclerosis, with T cell responses against ANO2 occurring in over half of patients.
These ANO2-specific T cells shar...
www.cell.com
January 15, 2026 at 1:41 AM
Epstein-Barr Virus #EBV was linked to #MultipleSclerosis - now a plausible cause has been found, misidentification by longterm memory T-cells that pick on the wrong protein, ANO2, instead of the EBV-antigen. Massive inflection towards the elimination of MS!!!
🧪🧠Cell www.cell.com/cell/fulltex...
🧪🧠Cell www.cell.com/cell/fulltex...
Reposted by Max Renner
The MITOscience of tomorrow is back.
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
January 14, 2026 at 3:14 PM
The MITOscience of tomorrow is back.
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Three short mitochats presented by
Débora Santos Rocha @deborasrocha.bsky.social ,
Valentin L’Hôte @valentinlhote.bsky.social and
Marijana Croon @marijanacroon.bsky.social
Visit mitotalks.org for zoom link details.
Will you time travel with us?
Reposted by Max Renner
We extracted (parts of) 12 books in experiments with 4 frontier-lab, production LLMs.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
January 7, 2026 at 8:31 PM
We extracted (parts of) 12 books in experiments with 4 frontier-lab, production LLMs.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
We prompted the LLMs with a short prefix of a book and asked them to complete the rest. For Harry Potter and the Sorcerer’s Stone, we extracted 95.8% of the book from jailbroken Claude 3.7 Sonnet.
Reposted by Max Renner
From inert nutshell to transcriptional factory: a remarkable discovery showing how a simple viral capsid springs to life upon access to NTPs in the infected cell.
January 9, 2026 at 10:58 AM
From inert nutshell to transcriptional factory: a remarkable discovery showing how a simple viral capsid springs to life upon access to NTPs in the infected cell.
If you are looking for a postdoc position in infection biology and cryo-EM, I can only recommend you apply. This is an opportunity to work with an excellent PI and in a friendly and supportive team.
January 11, 2026 at 4:04 PM
If you are looking for a postdoc position in infection biology and cryo-EM, I can only recommend you apply. This is an opportunity to work with an excellent PI and in a friendly and supportive team.
Reposted by Max Renner
I am pleased to share our new paper in Molecular Cell:
“Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6.”
We visualized, in structural detail, how a double-stranded RNA virus switches from a quiescent to a transcriptionally active state.
Link in the comments
“Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6.”
We visualized, in structural detail, how a double-stranded RNA virus switches from a quiescent to a transcriptionally active state.
Link in the comments
January 8, 2026 at 6:24 PM
I am pleased to share our new paper in Molecular Cell:
“Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6.”
We visualized, in structural detail, how a double-stranded RNA virus switches from a quiescent to a transcriptionally active state.
Link in the comments
“Capsid restructuring activates semi-conservative dsRNA transcription in cystovirus ɸ6.”
We visualized, in structural detail, how a double-stranded RNA virus switches from a quiescent to a transcriptionally active state.
Link in the comments
Reposted by Max Renner
TAPPER: Can you rule out the US is going to take Greenland by force?
MILLER: Greenland should be part of the US. By what right does Denmark assert control over Greenland? The US is the power of NATO
T: So force is on the table?
M: Nobody is gonna fight the US militarily over future of Greenland
MILLER: Greenland should be part of the US. By what right does Denmark assert control over Greenland? The US is the power of NATO
T: So force is on the table?
M: Nobody is gonna fight the US militarily over future of Greenland
January 5, 2026 at 11:26 PM
TAPPER: Can you rule out the US is going to take Greenland by force?
MILLER: Greenland should be part of the US. By what right does Denmark assert control over Greenland? The US is the power of NATO
T: So force is on the table?
M: Nobody is gonna fight the US militarily over future of Greenland
MILLER: Greenland should be part of the US. By what right does Denmark assert control over Greenland? The US is the power of NATO
T: So force is on the table?
M: Nobody is gonna fight the US militarily over future of Greenland
Reposted by Max Renner
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social as usual not pulling any punches
@dereklowe.bsky.social as usual not pulling any punches
Last Year, and the Year to Come
www.science.org
January 5, 2026 at 9:27 AM
„Never forget: whenever Elon Musk walks up to a podium to bullshit you about colonizing Mars or whatever, he is walking on the bodies of dead children. He yanked their food and medicine away while telling lies and cracking stupid jokes.“
@dereklowe.bsky.social as usual not pulling any punches
@dereklowe.bsky.social as usual not pulling any punches
Reposted by Max Renner
I have to bring a magic ring to a volcano and yeet it in 🤔
December 30, 2025 at 2:05 PM
I have to bring a magic ring to a volcano and yeet it in 🤔
Reposted by Max Renner
Atomic resolution structure of spinach rubisco reveals protons and dynamics
@cblikstad.bsky.social
www.biorxiv.org/content/10.6...
@cblikstad.bsky.social
www.biorxiv.org/content/10.6...
Atomic resolution structure of spinach rubisco reveals protons and dynamics
Photosynthetic organisms sustain life on Earth by storing solar energy in biomass. Central to this process is rubisco, the enzyme that catalyses the fixation of CO2 to ribulose-1,5-bisphosphate, provi...
www.biorxiv.org
December 27, 2025 at 9:11 PM
Atomic resolution structure of spinach rubisco reveals protons and dynamics
@cblikstad.bsky.social
www.biorxiv.org/content/10.6...
@cblikstad.bsky.social
www.biorxiv.org/content/10.6...
Really exciting new research from our friendly colleagues down the hall 🤩🤩🤩
New preprint from the lab is out! 🥳
We systematically profiled all pairwise growth interactions between 36 representative human gut microbiome strains, and delved deeper into the molecular mechanisms behind specific growth interactions.
www.biorxiv.org/content/10.6...
👇
We systematically profiled all pairwise growth interactions between 36 representative human gut microbiome strains, and delved deeper into the molecular mechanisms behind specific growth interactions.
www.biorxiv.org/content/10.6...
👇
Systematic profiling of growth interactions in human gut microbiome species
Microbial interactions shape the composition and stability of the human gut microbiome. Yet, the molecular mechanisms underlying these relationships remain poorly understood. Here, we systematically p...
www.biorxiv.org
December 22, 2025 at 11:42 AM
Really exciting new research from our friendly colleagues down the hall 🤩🤩🤩
Reposted by Max Renner
An important question is, who is citing those papers?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Should it be considered misconduct to not even check whether what you are citing *exists*?
December 20, 2025 at 4:15 PM
An important question is, who is citing those papers?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Should it be considered misconduct to not even check whether what you are citing *exists*?
Reposted by Max Renner
🎄✨ Season’s Greetings from PDBe ✨🎄
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
December 18, 2025 at 2:12 PM
🎄✨ Season’s Greetings from PDBe ✨🎄
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
The PDBe wishes you a very Merry Christmas and a Happy New Year. We are delighted to share our jointly designed EMDB/PDBe Christmas card with you. It has been a busy year, and we look forward to seeing you in the New Year.
Same with universities, in my humble opinion...
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
December 17, 2025 at 8:38 AM
Same with universities, in my humble opinion...
Reposted by Max Renner
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
December 17, 2025 at 8:21 AM
The whole idea of responsible AI use is just companies encouraging people to use tools irresponsibly while telling people to use them responsibly.
Reposted by Max Renner
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
The vault associates with membranes in situ
The eukaryotic vault particle is a giant ribonucleoprotein complex that assembles into an iconic barrel-like cage. Its cellular function has remained elusive despite extensive characterization. Using ...
www.biorxiv.org
December 16, 2025 at 6:35 AM
Vaults. They are cell biology's greatest puzzle! This preprint from Martin Beck's lab shows them docked on ER membranes with a ribosome inside. What on earth is going on there??
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
#CellBiology #WTFology
www.biorxiv.org/content/10.6...
Reposted by Max Renner
BBC News - Flu cases likely to 'spike' in coming weeks, warns health secretary - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Flu cases likely to 'spike' in coming weeks, warns health secretary
Neil Gray says the rise in cases is a challenge and urges anyone able to get vaccinated to do so.
www.bbc.co.uk
December 7, 2025 at 2:19 PM
BBC News - Flu cases likely to 'spike' in coming weeks, warns health secretary - BBC News
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Reposted by Max Renner
Only a few days left to apply for this PhD opportunity in my lab! More details and how to apply at: www.findaphd.com/phds/project...
December 1, 2025 at 5:40 PM
Only a few days left to apply for this PhD opportunity in my lab! More details and how to apply at: www.findaphd.com/phds/project...
Reposted by Max Renner
Heute ist Welt-AIDS-Tag. HIV hat seinen Schrecken als tödliche Erkrankung verloren. Trotz des medizinischen Fortschritts steigen jedoch die Neuinfektionen, auch hier in Deutschland, und Infektionen werden spät diagnostiziert. (1/2)
www.tagesschau.de/wissen/gesun...
www.tagesschau.de/wissen/gesun...
Warum auch in Deutschland die HIV-Infektionszahlen steigen
Im vergangenen Jahr gab es in Deutschland mehr HIV-Neuinfektionen als im Jahr davor. Viele Infektionen werden erst im fortgeschrittenen Stadium erkannt - für Experten der Aidshilfe ein Alarmzeichen. V...
www.tagesschau.de
December 1, 2025 at 6:26 PM
Heute ist Welt-AIDS-Tag. HIV hat seinen Schrecken als tödliche Erkrankung verloren. Trotz des medizinischen Fortschritts steigen jedoch die Neuinfektionen, auch hier in Deutschland, und Infektionen werden spät diagnostiziert. (1/2)
www.tagesschau.de/wissen/gesun...
www.tagesschau.de/wissen/gesun...
Reposted by Max Renner
🚨👇One week left to apply for this fully-funded PhD project to study RNA-protein complexes regulating enterovirus genome replication:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York on FindAPhD.com
PhD Project - MRC DiMeN Doctoral Training Partnership: Understanding molecular mechanisms of protein-primed genome replication in enteroviruses at University of York, listed on FindAPhD.com
www.findaphd.com
November 28, 2025 at 12:41 PM
🚨👇One week left to apply for this fully-funded PhD project to study RNA-protein complexes regulating enterovirus genome replication:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Max Renner
What do you think?
Real SDS-PAGE gel or AI-generated ?
Real SDS-PAGE gel or AI-generated ?
November 26, 2025 at 7:47 AM
What do you think?
Real SDS-PAGE gel or AI-generated ?
Real SDS-PAGE gel or AI-generated ?
Reposted by Max Renner
It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.
#virology #cryoEM
go.bsky.app/Qxv95BL
#virology #cryoEM
go.bsky.app/Qxv95BL
November 25, 2025 at 9:46 AM
It’s been a while since I put together the Structural Virology starter pack, and I’m sure some new folks have joined Bluesky since then. There’s still plenty of space to fill, so if you’d like to be added to the list just let me know.
#virology #cryoEM
go.bsky.app/Qxv95BL
#virology #cryoEM
go.bsky.app/Qxv95BL