Lightnews — Scholar-powered news

Reposted by Erin E. Cutts

Aga Gambus @agagambus.bsky.social · 3d

We are looking for a senior technician (can undertake PhD) at Uni of Birmingham (UK) to study chromatin replication and ubiquitylation using Xenopus egg extract. Deadline 28/10/25. Get in touch with me or @m-saponaro.bsky.social for informal inquiries. Please share.
www.jobs.ac.uk/job/DOW912/s...

Senior Research Technician at University of Birmingham

Explore an exciting academic career as a Senior Research Technician. Don't miss out on other academic jobs. Click to apply and explore more opportunities.

www.jobs.ac.uk

13 8

Erin E. Cutts @eecutts.bsky.social · 21d

But how muddy did puppy get this time?

1

Reposted by Erin E. Cutts

Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · Aug 16

New preprint with @gfudenberg.bsky.social

We find the rate of cohesin loop extrusion in cells is set by NIPBL dosage and tunes many aspects of chromosome folding.

This provides a molecular basis for NIPBL haploinsufficiency in humans. 🧵👇

www.biorxiv.org/content/10.1...

NIPBL dosage shapes genome folding by tuning the rate of cohesin loop extrusion

Cohesin loop extrusion is a major driver of chromosome folding, but how its dynamics are controlled to shape the genome remains elusive. Here we disentangle the contributions of the cohesin cofactors ...

www.biorxiv.org

1 50 110

Reposted by Erin E. Cutts

John Lees @bacpop.org · Aug 15

My PhD student @leonielorenz.bsky.social (with Eva Geissen) has made this nice (free) online course to introduce mathematical modelling for biology:
www.ebi.ac.uk/training/onl...

Including both molecular and epidemiological examples

Mathematical modelling for biologists - Modelling concepts in biological research

www.ebi.ac.uk

7 56 110

Reposted by Erin E. Cutts

Biophysical Society @biophysicalsoc.bsky.social · Aug 7

It's more important than ever for students and educators to stay informed and proactive. That's why you're invited to our upcoming webinar “The Future of Graduate Education in Biophysics"

September 4, 3:30-5:00PM USA Eastern
my.biophysics.org/events/calen...

Meeting Home Page

Displays details of a selected meeting including Date, Time, location, and additional content.

my.biophysics.org

2 2

Reposted by Erin E. Cutts

RSC Nucleic Acids Group @rscnucleicacids.bsky.social · Jul 11

Starting off our NAF 2025 meeting with an introduction of the RSC Nucleic Acids Group's new chair, Marco Di Antonio! An exciting new era for our group begins! 🧬
@diantoniogroup.bsky.social

1 4 7

Reposted by Erin E. Cutts

Dan Bose @danbose.bsky.social · Jul 5

This is a proper tour de force of integrative structural biology and biochem! (Including from our own @eecutts.bsky.social @mcb-sheffield.bsky.social) so many crucial roles for SLiMs in fundamental cellular processes.

Molecular Cell @cp-molcell.bsky.social · Jul 3

Online Now: Condensin II activation by M18BP1 Online now:

Condensin II activation by M18BP1

Borsellini, Conti, Cutts, Harris, et al. identify an interaction between M18BP1 and condensin II that is essential for condensin II activity and chromatin localization. MCPH1 keeps the interphase genome uncondensed by competing with M18BP1. A phosphorylation-driven switch allows M18BP1 to trigger condensation at mitotic onset.

dlvr.it

1 7

Reposted by Erin E. Cutts

Alessandro Vannini @alessandrovannini.bsky.social · Jul 3

Condensin II activation by M18BP1: Molecular Cell www.cell.com/molecular-ce...

Condensin II activation by M18BP1

Borsellini, Conti, Cutts, Harris, et al. identify an interaction between M18BP1 and condensin II that is essential for condensin II activity and chromatin localization. MCPH1 keeps the interphase geno...

www.cell.com

4 16

Reposted by Erin E. Cutts

Michael @schlierflab.bsky.social · Jun 17

JOB OPENING for biochemist/-physicst 🧑‍🔬: This isn't an official job ad yet. We are looking for a postdoc working on large to high throughout single-molecule FRET on protein structures and dynamics. The project will be run in our lab and co-directed jointly with a team from big pharma/biotech. 1/2

2 8 10

Reposted by Erin E. Cutts

Michael Ranes @michaelranes.bsky.social · May 8

Job Alert 🔊🔊
Looking for your first or next Postdoc position? Then don't look further, apply to this opportunity to join our lab to tackle the next big challenges in the Wnt signalling field. Experience in protein biochemistry and in vitro cell biology is essential for this post tinyurl.com/2p9rndfy

4 6

Erin E. Cutts @eecutts.bsky.social · May 3

I was really hoping you were going to post some puppy party photos. There can never be too many puppy pictures in the world.

1

Erin E. Cutts @eecutts.bsky.social · May 3

Different author, but this was one of the worst ones I found, deposited as 3.2A, published in NSMB. I emailed the authors and they saw no issue depositing the structure where only half the density was there...

2 6

Reposted by Erin E. Cutts

Ylva Ivarsson @ivarssonlab.bsky.social · Apr 25

Looking for a senior lecturer (associate #professor) position in #biochemistry? Come and join our neighbouring department at Uppsala University: www.uu.se/en/about-uu/...

Senior lecturer in medical biochemistry - Uppsala University

Senior lecturer in medical biochemistry , Disciplinary Domain of Medicine and Pharmacy, Faculty of Medicine, Department of Medical Biochemistry and Microbiology, Uppsala University

www.uu.se

6 3

Reposted by Erin E. Cutts

Chris Toseland @christoseland.bsky.social · Apr 23

Less than two weeks to go! Thanks for all the donations!

www.justgiving.com/team/thalia

2 5

Reposted by Erin E. Cutts

Anton Goloborodko @golobor.bsky.social · Apr 11

Earnshaw, Goloborodko, Dekker & Mirny labs are excited to present our latest work, "Rules of engagement for condensins and cohesins guide mitotic chromosome formation" - now accepted!!
www.science.org/doi/10.1126/...
A short clip describing the key results:
www.youtube.com/watch?v=pmvO...

Rules of Engagement

YouTube video by Johan Gibcus

www.youtube.com

7 53 98

Reposted by Erin E. Cutts

Leo Kiss @leokiss.bsky.social · Mar 27

Fantastic new work on substrate recognition by separase!

www.biorxiv.org/content/10.1...

Substrate recognition by human separase

The protein complex cohesin encircles the sister chromatids in early mitosis. At anaphase onset, sister separation is triggered by cleavage of the cohesin subunit SCC1/RAD21 by the cysteine protease s...

www.biorxiv.org

4 8

Erin E. Cutts @eecutts.bsky.social · Mar 10

Anyone looking for a PhD: the second deadline of the Yorkshire DTP closes this Friday, the 14th. Get in touch asap if you are interested in working with me on condensin complexes!
www.findaphd.com/phds/project...

Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield on FindAPhD.com

PhD Project - Developing Imaging Solutions to Study the Dynamics of Human Condensin I at University of Sheffield, listed on FindAPhD.com

www.findaphd.com

2 4

Reposted by Erin E. Cutts

Nynke Dekker Lab @nynkedekkerlab.bsky.social · Mar 10

Deadline for abstract submission (for poster/short talk presentation) extended until March 14 - after that we will open registration for scientific participants without abstracts.

Nynke Dekker Lab @nynkedekkerlab.bsky.social · Feb 17

The UK&Ireland single-molecule meeting 2025 will be held in Oxford on May 14 and 15 - deadline for abstract submission March 7 - submit one and join us! Here is the link:
lumicks.com/uk-single-mo...

UK Single-molecule Meeting 2025 – LUMICKS

lumicks.com

1 1

Reposted by Erin E. Cutts

Dr. Ahna Skop @ahnaskop.bsky.social · Mar 8

Another fave

15 110 530

Reposted by Erin E. Cutts

mehmet can uçar @mehmetcanucar.bsky.social · Mar 4

Very happy to see this out! 😍

Tissue-like lipid networks with motile bacteria undergo large remodeling events, leading to active “hubs” & tissue fluidization!

This was a super fun collab w Jan Steinkuhler lab!

www.nature.com/articles/s41...

Remodeling of lipid-foam prototissues by network-wide tension fluctuations induced by active particles - Nature Communications

Constructing synthetic prototissues is a challenge in bottom-up synthetic biology. Here, the authors introduce a “lipid foam” tissue mimetic and demonstrate network-wide tension fluctuations upon comp...

www.nature.com

5 18

Reposted by Erin E. Cutts

Adele Marston @marstonlab.bsky.social · Feb 6

Don’t miss the early bird registration for this exciting meeting focused on neglected areas of genetics, cellular and structural biology. Lots of slots for speakers selected from abstracts. 2-4 April 2025 in Edinburgh.

Wendy Bickmore @wbickmor.bsky.social · Nov 12

Interested in difficult to access parts of genetics, cellular & structural biology? Join us in Edinburgh 2-4th April 2025 for "Hidden Cell, Dark Genome"
Regulation in the dark genome
Uncharted proteins, RNA complexity
Atomic structures at cellular scale
Cell diversity
www.ed.ac.uk/c/hidden-cel...

6 7

Reposted by Erin E. Cutts

Anestis Tsakiridis @tsakiridis.bsky.social · Feb 20

Development folks: the next Northern England Developmental Biology @bsdb.bsky.social @biologists.bsky.social meeting will take place on the 10th of July in Sheffield. Great speaker line-up, cheap registration fee and plenty of slots for ECR talks. Registration deadline=31/5, see poster for details

1 10 9

Erin E. Cutts @eecutts.bsky.social · Feb 25

Oh that’s so sad!

1

Reposted by Erin E. Cutts

Science of the Times Podcast @scienceofthetimes.bsky.social · Feb 25

Our first introductory episode will go live tomorrow!

@timcoulson.bsky.social @sykhalid.bsky.social @streamingspires.bsky.social

scienceofthetimes.transistor.fm

Science Of The Times

Do you want to learn a little more about topical science findings? Do many of the science stories you hear leave you with unanswered questions? Syma and Tim will discuss in non-technical language and ...

scienceofthetimes.transistor.fm

5 13

Reposted by Erin E. Cutts

Fiona Whelan @freewhelan.bsky.social · Feb 21

Happy to report our enzyme found a home! rdcu.be/eaGXG New kid on the block P450 O-demethylase SyoA-the specificity of a monooxygenase with the simplicity of catalysis driven by peroxide. Retrofit your P450 with this active site chemistry today! #lignin #syringol Out today in Nature Communications.

8 11 39