Stephen Royle
@steveroyle.bsky.social
I'm into chord changes and cell biology.
Professor - University of Warwick. Director - The Company of Biologists. Views are my own and not those of any organisation I am associated with.
Mastodon: @[email protected]
Lab: https://roylelab.org
Professor - University of Warwick. Director - The Company of Biologists. Views are my own and not those of any organisation I am associated with.
Mastodon: @[email protected]
Lab: https://roylelab.org
Reposted by Stephen Royle
Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...
January 12, 2026 at 2:33 PM
Preprints of pandemic potential - new historical piece from me on the history of bioRxiv/medRxiv, their role in the pandemic, and the way forward. 1/n journals.asm.org/doi/10.1128/...
Reposted by Stephen Royle
BSCB NextGen kicks off tomorrow at 14.00 BST. Don't forget to register your place!
Happy New Year from the BSCB! We're very excited to announce 'BSCB NextGen', a new monthly online seminar series aimed at ECRs in Cell Biology.
The series kicks off on 13th January
For full details and how to register see:
bscb.org/announcing-b...
The series kicks off on 13th January
For full details and how to register see:
bscb.org/announcing-b...
January 12, 2026 at 11:36 AM
BSCB NextGen kicks off tomorrow at 14.00 BST. Don't forget to register your place!
Reposted by Stephen Royle
Saddened to learn of the death of Richard Hynes. A giant of cell biology, Richard made a massive contribution to extracellular matrix and cancer biology - in particular early work on fibronectin en.wikipedia.org/wiki/Richard...
Richard Hynes - Wikipedia
en.wikipedia.org
January 10, 2026 at 10:15 PM
Saddened to learn of the death of Richard Hynes. A giant of cell biology, Richard made a massive contribution to extracellular matrix and cancer biology - in particular early work on fibronectin en.wikipedia.org/wiki/Richard...
Reposted by Stephen Royle
Anyone curious about a typical academic workload might be interested (short thread). I crossed 17 items off my to-do list this past week. The list now stands at 59 items (this includes 15 items that were freshly added last week - a lower-than-average spawning number as we're just after holidays).
January 10, 2026 at 9:40 AM
Anyone curious about a typical academic workload might be interested (short thread). I crossed 17 items off my to-do list this past week. The list now stands at 59 items (this includes 15 items that were freshly added last week - a lower-than-average spawning number as we're just after holidays).
Reposted by Stephen Royle
Cool new paper from the Munro lab!
The small #GTPase Rab1 is a master regulator of #Golgi traffic and #autophagy. van Vliet, Munro et al. @mrclmb.bsky.social performed a proteomic screen to identify novel Rab1 effectors, including a #dynein motor adaptor and cargo receptors for autophagy. rupress.org/jcb/article/...
#Trafficking
#Trafficking
January 9, 2026 at 9:21 PM
Cool new paper from the Munro lab!
Reposted by Stephen Royle
I think you can only really complain about a slow review process if, when reviewing, you submit your own reviews on time
January 9, 2026 at 5:40 PM
I think you can only really complain about a slow review process if, when reviewing, you submit your own reviews on time
Reposted by Stephen Royle
We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
Journal of Cell Science @jcellsci.bsky.social is recruiting an enthusiastic and motivated Reviews Editor. An exciting opportunity for a talented scientific editor to make a contribution to an important journal in the field of #cellbiology. Deadline 2 Feb.
More at: www.biologists.com/about-us/wor...
More at: www.biologists.com/about-us/wor...
Work for us
Working for us We’re always looking for talented and motivated people to work as part of our close-knit team. Roles range from editorial to production, marketing to event co-ordination, HR to accounts...
www.biologists.com
January 9, 2026 at 10:13 AM
We’re hiring!
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
@jcellsci.bsky.social is looking for a Reviews Editor to join the team. This is a fantastic opportunity for someone who loves #cellbiology and wants to stay connected with the field. A great chance to work for an organisation that believes in helping the community!
Details below👇
Physicists' perspective on the future direction of condensates in Cell Biology.
arxiv.org/abs/2601.03677
arxiv.org/abs/2601.03677
Roadmap for Condensates in Cell Biology
Biomolecular condensates govern essential cellular processes yet elude description by traditional equilibrium models. This roadmap, distilled from structured discussions at a workshop and reflecting t...
arxiv.org
January 8, 2026 at 8:35 AM
Physicists' perspective on the future direction of condensates in Cell Biology.
arxiv.org/abs/2601.03677
arxiv.org/abs/2601.03677
Reposted by Stephen Royle
Early bird deadline in 10 days!! This is going to be amazing!
Early-bird deadline to join @jcellsci.bsky.social at their meeting on Imaging Cell Dynamics in Spain in May is Friday 16 January. Apply to attend at:
biologists.com/meetings/jcs...
#JCSimaging
biologists.com/meetings/jcs...
#JCSimaging
January 6, 2026 at 7:12 PM
Early bird deadline in 10 days!! This is going to be amazing!
Reposted by Stephen Royle
Our paper describing the development of ShapeSpaceExplorer is now out: journals.plos.org/ploscompbiol... The software and documentation is available here: github.com/cmcb-warwick... Explainer thread below.
January 6, 2026 at 3:47 PM
Our paper describing the development of ShapeSpaceExplorer is now out: journals.plos.org/ploscompbiol... The software and documentation is available here: github.com/cmcb-warwick... Explainer thread below.
Reposted by Stephen Royle
'(...) it can be difficult to know where to get started with image analysis, given the abundance of tools and techniques that are available. As of this blog post, the BioImage Informatics Index (biii.eu), which keeps track of image analysis tools, lists over 1400 pieces of software!'
How do I get started with image analysis? - FocalPlane
How do I get started with image analysis? - AIC at HHMI Janelia
focalplane.biologists.com
January 5, 2026 at 7:15 AM
'(...) it can be difficult to know where to get started with image analysis, given the abundance of tools and techniques that are available. As of this blog post, the BioImage Informatics Index (biii.eu), which keeps track of image analysis tools, lists over 1400 pieces of software!'
Reposted by Stephen Royle
A tribute to Stuart Kornfeld, pioneering #glycotime scientist whose work on mannose-6-phosphate receptor lysosomal trafficking (among many other contributions) was highly influential to our work 🫡
www.jci.org/articles/vie...
www.jci.org/articles/vie...
JCI -
A tribute to Stuart A. Kornfeld (1936–2025)
www.jci.org
January 3, 2026 at 3:08 AM
A tribute to Stuart Kornfeld, pioneering #glycotime scientist whose work on mannose-6-phosphate receptor lysosomal trafficking (among many other contributions) was highly influential to our work 🫡
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Reposted by Stephen Royle
2025 was the year we stopped debating whether paying peer reviewers might work and started showing that it does.
December 31, 2025 at 10:13 PM
2025 was the year we stopped debating whether paying peer reviewers might work and started showing that it does.
I forgot to post my 2025 #running shenanigans here. The goal was to get to 3650 km (10 km per day). I reached that on Dec 24th and ended on 3672 km. Aim for 2026 is for less total distance and to improve my marathon time. I ran 3 this year and knocked off 8 min, but feel I can do better.
December 31, 2025 at 10:26 PM
I forgot to post my 2025 #running shenanigans here. The goal was to get to 3650 km (10 km per day). I reached that on Dec 24th and ended on 3672 km. Aim for 2026 is for less total distance and to improve my marathon time. I ran 3 this year and knocked off 8 min, but feel I can do better.
Good morning, cells!
Surprisingly hard to get a good picture down the TC microscope.
Surprisingly hard to get a good picture down the TC microscope.
December 26, 2025 at 9:42 AM
Good morning, cells!
Surprisingly hard to get a good picture down the TC microscope.
Surprisingly hard to get a good picture down the TC microscope.
Reposted by Stephen Royle
We have been busy celebrating our 100-year anniversary this year. Scroll through our timeline to view the key milestones over the years www.biologists.com/100-years/ti...
#biologists100
#biologists100
100 years timeline
Back to 100 years anniversary page
www.biologists.com
December 24, 2025 at 1:42 PM
We have been busy celebrating our 100-year anniversary this year. Scroll through our timeline to view the key milestones over the years www.biologists.com/100-years/ti...
#biologists100
#biologists100
Reposted by Stephen Royle
Should funders mandate where grantees can publish?
Probably not.
But funders could mandate where grantees cannot publish.
🧵
1/11
Probably not.
But funders could mandate where grantees cannot publish.
🧵
1/11
December 24, 2025 at 12:12 AM
Should funders mandate where grantees can publish?
Probably not.
But funders could mandate where grantees cannot publish.
🧵
1/11
Probably not.
But funders could mandate where grantees cannot publish.
🧵
1/11
Reposted by Stephen Royle
Enjoy these human epithelial cell nuclei - especially the bagel with a hole right through the middle!
MCF10A cells with labelled with DNA (blue; Hoechst), anti-lamin A/C (green), and F-actin (magenta; phalloidin).
3D z-stack taken with a Zeiss CellDiscoverer7 + LSM 900 Airyscan-2, 20X (NA 0.95).
MCF10A cells with labelled with DNA (blue; Hoechst), anti-lamin A/C (green), and F-actin (magenta; phalloidin).
3D z-stack taken with a Zeiss CellDiscoverer7 + LSM 900 Airyscan-2, 20X (NA 0.95).
December 23, 2025 at 3:32 PM
Enjoy these human epithelial cell nuclei - especially the bagel with a hole right through the middle!
MCF10A cells with labelled with DNA (blue; Hoechst), anti-lamin A/C (green), and F-actin (magenta; phalloidin).
3D z-stack taken with a Zeiss CellDiscoverer7 + LSM 900 Airyscan-2, 20X (NA 0.95).
MCF10A cells with labelled with DNA (blue; Hoechst), anti-lamin A/C (green), and F-actin (magenta; phalloidin).
3D z-stack taken with a Zeiss CellDiscoverer7 + LSM 900 Airyscan-2, 20X (NA 0.95).
Reposted by Stephen Royle
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
At the helm of JCS – Editors-in-Chief past, present… and future
The Editor-in-Chief (EIC) of Journal of Cell Science plays a key role in defining the overall vision of the journal, helping to decide on journal strategy, policy and priorities, and overseeing all co...
doi.org
December 22, 2025 at 10:33 AM
What's it like being Editor-in-chief of @jcellsci.bsky.social? doi.org/10.1242/jcs....
Reposted by Stephen Royle
We were delighted to support the UK Membrane Trafficking Meeting organised by @jezcarlton.bsky.social and Chris Stefan. It sounds like the meeting was a huge success once again. Congratulations to Nikita Zubkoc (Munro lab) and Jack Stanley @edenlab.bsky.social, winners of the JCS short talk prizes.
December 16, 2025 at 4:21 PM
We were delighted to support the UK Membrane Trafficking Meeting organised by @jezcarlton.bsky.social and Chris Stefan. It sounds like the meeting was a huge success once again. Congratulations to Nikita Zubkoc (Munro lab) and Jack Stanley @edenlab.bsky.social, winners of the JCS short talk prizes.
Reposted by Stephen Royle
If you're wondering if your manuscript could be suitable for our special issue but are unsure, don't hesitate to reach out 👍
In parallel, we'll be publishing a special issue on Imaging Cell Architecture and Dynamics - you can find out more at:
journals.biologists.com/jcs/pages/im...
Submission deadline: 1 April 2026
#imaging #microscopy #cellbiology
journals.biologists.com/jcs/pages/im...
Submission deadline: 1 April 2026
#imaging #microscopy #cellbiology
Registration for our Imaging Cell Dynamics meeting is still open! Organised by @franbottanelli.bsky.social, @guijacquemet.bsky.social, @drmichaelway.bsky.social and @giuliazanetti.bsky.social.
Find out more: www.biologists.com/meetings/jcs...
Early-bird deadline: 16 January
#imaging #microscopy
Find out more: www.biologists.com/meetings/jcs...
Early-bird deadline: 16 January
#imaging #microscopy
December 18, 2025 at 8:26 PM
If you're wondering if your manuscript could be suitable for our special issue but are unsure, don't hesitate to reach out 👍
Reposted by Stephen Royle
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Organelles harbour pH gradients https://www.biorxiv.org/content/10.64898/2025.12.12.694065v1
December 17, 2025 at 12:46 AM
Organelles do NOT have a single uniform pH.
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
And if you think they must, because “protons diffuse fast,” this paper is for you.
A thread on why that assumption is wrong; and what we found instead. 🧵 1/n
Reposted by Stephen Royle
Why do people publish in shoddy journals?
Last month, Science of the Total Environment was delisted from Clarivate’s Web of Science. Delisting is often a death knell. It signals a journal no longer meets expectations for publication ethics or quality.
🧵1/8
english.elpais.com/science-tech...
Last month, Science of the Total Environment was delisted from Clarivate’s Web of Science. Delisting is often a death knell. It signals a journal no longer meets expectations for publication ethics or quality.
🧵1/8
english.elpais.com/science-tech...
The fall of a prolific science journal exposes the billion-dollar profits of scientific publishing
One of the 15 publications that put out the most studies globally has been expelled from the indexing system for irregularities. Its publisher, Elsevier, has a 38% profit margin that reached $1.5 bill...
english.elpais.com
December 16, 2025 at 11:36 PM
Why do people publish in shoddy journals?
Last month, Science of the Total Environment was delisted from Clarivate’s Web of Science. Delisting is often a death knell. It signals a journal no longer meets expectations for publication ethics or quality.
🧵1/8
english.elpais.com/science-tech...
Last month, Science of the Total Environment was delisted from Clarivate’s Web of Science. Delisting is often a death knell. It signals a journal no longer meets expectations for publication ethics or quality.
🧵1/8
english.elpais.com/science-tech...
Can anyone on a BBSRC panel answer this question:
Are hyperlinked references allowed in grant applications (i.e. no reference section)?
TFS guidance only says "references may be included in this section" for Vision and Approach. Previously hyperlinks were not allowed, but has this changed?
Are hyperlinked references allowed in grant applications (i.e. no reference section)?
TFS guidance only says "references may be included in this section" for Vision and Approach. Previously hyperlinks were not allowed, but has this changed?
December 16, 2025 at 9:14 AM
Can anyone on a BBSRC panel answer this question:
Are hyperlinked references allowed in grant applications (i.e. no reference section)?
TFS guidance only says "references may be included in this section" for Vision and Approach. Previously hyperlinks were not allowed, but has this changed?
Are hyperlinked references allowed in grant applications (i.e. no reference section)?
TFS guidance only says "references may be included in this section" for Vision and Approach. Previously hyperlinks were not allowed, but has this changed?
I had a great day yesterday at UK Membrane Traffic in London. Too many highlights to mention. There's so much exciting work in this field! This year there was a poster session which was a great addition to get more people involved in the meeting. Thanks to Chris Stefan & Jez Carlton for organising.
December 16, 2025 at 6:39 AM
I had a great day yesterday at UK Membrane Traffic in London. Too many highlights to mention. There's so much exciting work in this field! This year there was a poster session which was a great addition to get more people involved in the meeting. Thanks to Chris Stefan & Jez Carlton for organising.