Lightnews — Scholar-powered news

Reposted by New York Genome Center

NY-CURES @nycures.bsky.social · 3d

From patient to scientist: Sergei German beat cancer thanks to clinical trials, inspiring him to leave his career in finance and drive research @nygenome.org

A NY statewide biomedical institute will make more incredible stories like his possible.

Help make this happen, sign up at www.nycures.org/

New York Cures – NY-CURESNew York Cures Website

NY-CURES is working to advance bold, state-backed investment in biomedical research—on the scale of successful initiatives in California and Texas—to grow New York’s leadership in science, innovation, and health.

www.nycures.org

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Reposted by New York Genome Center

Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · 26d

Meet Beatrice Grauman, PhD student in the Vicković Lab at @nygenome.org 🌟. Her research explores tumor–microenvironment interactions and cancer evolution.
🎥Find out what inspires her outside the lab in our latest Faces of IICD feature
🔗 bit.ly/3K0Xidr
#FacesOfIICD #PhDLife #WomenInSTEM

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Alex @alexpellancheng.bsky.social · Aug 14

Massive team effort. A huge thank you to the Ultima Genomics team, our clinical collaborators and sequencing team @nygenome.org
Look at the author list, it's huge! Takes a village. Super proud of trainees Aaron, Sam and Sri

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Reposted by New York Genome Center

Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · Jul 14

Our intern spotlight continues with Joel Joseph, a CS + Data Science senior @arizonastate.bsky.social. Mentored by Dr. Sanja Vicković @nygenome.org, his research focuses on using computational tools to study tumor interactions in colorectal cancer. bit.ly/SRPQA2025 @columbiauniversity.bsky.social

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Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · Jun 27

Meet Daniel Alshansky, a rising junior studying Biology & Computer Science @hofstrau.bsky.social. At the @nygenome.org Vicković Lab, he’s developing new transcriptomic engineering tools to push the boundaries of genomic research. Read more: bit.ly/SRPQA2025

Collage of Daniel Alshansky. Left: Daniel in a lab coat working with lab equipment at his bench. Top right: Daniel and Cody Slater in lab coats examining a sample together. Bottom right: Daniel seated, engaged in conversation with Joel Joseph.

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Reposted by New York Genome Center

Irving Institute for Cancer Dynamics @cancerdynamics.bsky.social · Jun 12

The SRP and Alliance interns had a great time touring the New York Genome Center this week! 🧬
Thanks to @nygenome.org for the warm welcome and an inside look at innovative research in action. #Genomics #SRP2025

SRP and Alliance interns in front of the New York Genome Center sign

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New York Genome Center @nygenome.org · Jun 11

NYGC Core Faculty Member @nevillesanjana.bsky.social presented at GEN bio’s “The State of CRISPR and Genome Editing” virtual summit. He spoke about CRISPR, the noncoding genome, & its potential to transform precision therapies.

For more on Dr. Sanjana’s work: bit.ly/43YshNC

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David A Knowles @davidaknowles.bsky.social · May 26

Just under a week until the #MLCB2025 paper/abstract deadline on June 1st! In-person registration is full but you can join the wait list forms.gle/gnj6AAV7oWj6... or watch online at youtube.com/@mlcbconf. Sept 10-11 at @nygenome.org. Full deets at mlcb.org! Please RP.

Machine Learning in Computational Biology

Youtube channel for the Machine Learning in Computational Biology conference.

youtube.com

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Reposted by New York Genome Center

David A Knowles @davidaknowles.bsky.social · May 15

Free in-person registration is open for #MLCB2025! Sept 10-11 at @nygenome.org and online at youtube.com/@mlcbconf. Paper/abstract deadline is June 1, more deets including our fantastic invited speaker lineup at mlcb.org! Please RP.

Machine Learning in Computational Biology

Youtube channel for the Machine Learning in Computational Biology conference: https://mlcb.github.io/

youtube.com

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Reposted by New York Genome Center

Kelsey Monson, PhD @kelseymonson.bsky.social · May 14

Our next NYC Postdoc Night Science event will be June 2nd! We'll start off at @nygenome.org, then head to a bar to continue the conversation.
Register here to join us! docs.google.com/forms/d/1s9W...

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Reposted by New York Genome Center

Tuuli Lappalainen @tuuliel.bsky.social · May 6

Our new contribution to the quest to find causal GWAS genes! Sam Ghatan from my lab at @nygenome.org led a systematic comparison of eQTLs and CRISPRi+scRNA-seq screens. TL;DR: they provide highly complementary insights, with ortogonal pros and cons. 🧵👇
www.biorxiv.org/content/10.1...

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New York Genome Center @nygenome.org · Apr 25

Single Cell Genomics Day 2025 has begun! Join the live stream here: satijalab.org/scgd25

New York Genome Center @nygenome.org · Apr 21

Join the Satija Lab for the seventh annual Single Cell Genomics Day on 4/25 — a free, one-day workshop featuring recent advances & practical insights in single cell genomics, designed for researchers at all levels.

All talks will be live-streamed via: satijalab.org/scgd25. Hope to see you there!

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New York Genome Center @nygenome.org · Apr 21

Join the Satija Lab for the seventh annual Single Cell Genomics Day on 4/25 — a free, one-day workshop featuring recent advances & practical insights in single cell genomics, designed for researchers at all levels.

All talks will be live-streamed via: satijalab.org/scgd25. Hope to see you there!

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Reposted by New York Genome Center

MSK Department of Medicine @mskdeptofmed.bsky.social · Apr 18

Adam Widman & collaborators at @nygenome.org led a study to evaluate a low-cost, error-corrected whole-genome sequencing method to detect cancer DNA & assess disease burden in individuals with melanoma and urothelial cancer. @mskcancercenter.bsky.social
www.nature.com/articles/s41...

Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling - Nature Methods

This work integrates duplex sequencing with cost-effective Ultima sequencing to enhance the accuracy of whole-genome circulating cell-free DNA profiling.

www.nature.com

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Reposted by New York Genome Center

The Chronicle of Philanthropy @chronphilanthropy.bsky.social · Apr 16

The New York Genome Center will receive $125 million from Simons Foundation International and the Carson Family Charitable Trust to continue its operations through 2029.
phlnthrp.com/4jfRPfs

#grantsroundup

New York Genome Center Receives $125 Million to Continue Operations

Plus, the 1803 Fund pledged $75 million to Oregon groups that serve Black youths, and the Bezos Earth Fund and the Global Methane Hub will give $27.4 million to lower methane emissions through livesto...

phlnthrp.com

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Reposted by New York Genome Center

Gamze Gürsoy @gamzeandgursoy.bsky.social · Apr 14

Super excited to share the first 3D genome paper from my lab @narjournal.bsky.social , led by my smart and hardworking student Carlos (joint with @LuLaboratory) with assists from a brilliant summer intern Narjis. (1/n) academic.oup.com/nar/article/...

pC-SAC: A method for high-resolution 3D genome reconstruction from low-resolution Hi-C data

Abstract. The three-dimensional (3D) organization of the genome is crucial for gene regulation, with disruptions linked to various diseases. High-throughpu

academic.oup.com

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Reposted by New York Genome Center

Alex @alexpellancheng.bsky.social · Apr 11

What happens when sequencing costs go ⏬ ?
Imagination and new opportunities go ⏫
@landau.bsky.social

Let's look at what you can do when you perform deep WGS on cfDNA for cancer detection. Our recent work with the
@UltimaGenomics
platform 🧵👇
Lets goooo!!
rdcu.be/ehkUb

Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling

Nature Methods - This work integrates duplex sequencing with cost-effective Ultima sequencing to enhance the accuracy of whole-genome circulating cell-free DNA profiling.

rdcu.be

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Reposted by New York Genome Center

Tuuli Lappalainen @tuuliel.bsky.social · Apr 7

Our vision for Precision Omics Initiative Sweden (PROMISE) is now published in Nature Medicine! By boosting data-driven precision omics in Sweden, we can not only empower research but also integrate it with healthcare in a new way, with an impact in 🇸🇪 and 🌎. 🧵: rdcu.be/egmXY

Precision Omics Initiative Sweden (PROMISE) will integrate research with healthcare

Nature Medicine - Precision Omics Initiative Sweden (PROMISE) will integrate research with healthcare

rdcu.be

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Reposted by New York Genome Center

Nicolas Robine @nicorobine.bsky.social · Mar 31

New publication from my @nygenome.org group, in close collaboration with @wcmenglanderipm.bsky.social colleagues Jones Nauseef, Juan-Miguel Mosquera!

A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer

www.nature.com/articles/s41...

A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer - npj Precision Oncology

npj Precision Oncology - A complex phylogeny of lineage plasticity in metastatic castration resistant prostate cancer

www.nature.com

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New York Genome Center @nygenome.org · Mar 27

We are proud to announce Bing Ren, PhD, as the new Scientific Director & CEO of the New York Genome Center

Dr. Ren brings his expertise in the fields of genomics & epigenetics to the NYGC & Columbia University, where he will hold a joint appointment.

For more on Dr. Ren: bit.ly/3DJXtah

Bing Ren Appointed Scientific Director and Chief Executive Officer of the New York Genome Center - March 27, 2025

Read about Bing Ren Appointed Scientific Director and Chief Executive Officer of the New York Genome Center at the New York Genome Center on March 27, 2025

bit.ly

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Columbia University's Zuckerman Institute @zuckermanbrain.bsky.social · Mar 17

For decades, government funding “has positioned the United States as a global leader” in science, says scientist Tom Maniatis of @zuckermanbrain.bsky.social and the New York Genome Center. He highlights how a new #NIH policy cutting money for research “jeopardizes” this, in Cell tinyurl.com/ubw6uphe

We must act swiftly and decisively to safeguard the future of science in the US - Tom Maniatis, PhD

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Reposted by New York Genome Center

Science Friday @scifri.bsky.social · Mar 14

Former NIH director Dr. Harold Varmus joins us to discuss what cuts to the institutes’ staff and research funding could mean for science.

How NIH Cuts Could Affect U.S. Biomedical Research

Former NIH director Dr. Harold Varmus speaks out about what recent budget cuts and policy changes could mean for science.

www.sciencefriday.com

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Reposted by New York Genome Center

Molly Gale (Gale-Hammell Lab) @mollygale.bsky.social · Mar 10

Super happy to announce the latest work from my lab together with Hemali Phatnani @nygenome.org & NYGC ALS Consortium!

We've combined ALS patient profiling (100s!), ML classifiers and matched bulk/single-cell data to dive into ALS Molecular Subtypes

#NIHfundedResearch
www.cell.com/cell-reports...

ALS molecular subtypes are a combination of cellular and pathological features learned by deep multiomics classifiers

O’Neill et al. present a deep exploration of molecular subtypes in ALS postmortem tissues from the NYGC ALS Consortium. Matched bulk and single-cell profiles demonstrate that ALS subtypes are a combin...

www.cell.com

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New York Genome Center @nygenome.org · Mar 5

We proudly recognize the 54 Nobel Laureates who have signed the NYGC’s petition urging NIH to reverse its recent policy change capping indirect funds. Thank you for your support and commitment to advancing scientific research at institutions nationwide

Learn more: bit.ly/3XupqJM

Over 50 Nobel Laureates in Support of NYGC’s NIH Policy Reversal Petition - March 4, 2025

Read about Over 50 Nobel Laureates in Support of NYGC’s NIH Policy Reversal Petition at the New York Genome Center on March 4, 2025

bit.ly

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Cell Press @cellpress.bsky.social · Mar 3

Following the NIH decision to cap funding for indirect cost reimbursements at 15%, @nygenome.org Scientific Director Tom Maniatis calls for swift, united action. cell.com/cell/fulltex...

Read his Commentary now in @cp-cell.bsky.social

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