Oliver Mueller-Cajar
@omc111.bsky.social
420 followers 1K following 6 posts
Cellular biochemistry of CO2 assimilation, NTU Singapore
Posts Media Videos Starter Packs
omc111.bsky.social
Sign up for the inaugural Singapore Biosciences Symposium at SBS, NTU. We have an outstanding lineup of speakers at the intersection of plant biology and biomolecular condensates!

www.ntu.edu.sg/sbs/symposiu...
SBS 2025
www.ntu.edu.sg
Reposted by Oliver Mueller-Cajar
savagecatsonly.bsky.social
What limits rubisco function? Is it the chemical mechanism? Evolution? In this paper, @prywes.bsky.social et. al explore this question by assaying >99% of single amino acid mutants in Form II rubisco (1/7) doi.org/10.1038/s415...
omc111.bsky.social
Noam presents the most state of the art Rubisco search engine.. great to see this out!
prywes.bsky.social
Fun to see it out in print! I was really lucky to have an amazing team to work with on this. If this sort of work seems interesting to you or someone you know, please feel free to reach out (planning to staff a lab later this year).
www.nature.com/articles/s41...
A map of the rubisco biochemical landscape - Nature
A massively parallel assay developed to map the essential photosynthetic enzyme rubisco showed that non-trivial biochemical changes and improvements in CO2 affinity are possible, signposting further e...
www.nature.com
Reposted by Oliver Mueller-Cajar
owenatkin.bsky.social
A great way to end the week - catching up with @omc111.bsky.social and Shawn Lum to discuss links between ANU and NTU, and ideas for how to extend thermal tolerance of photosynthesis. @ouranu.bsky.social
Reposted by Oliver Mueller-Cajar
cellarchlab.com
Beautiful study by Martin, Alistair, and crew on the membrane tubules that traverse the Chlamydomonas pyrenoid and help deliver a high concentration of #CO2 to Rubisco 🧪🌾
Reposted by Oliver Mueller-Cajar
natplants.nature.com
New Letter: "Rubisco supplies pyruvate for the 2-C-methyl-d-erythritol-4-phosphate pathway" rdcu.be/dVZMj

Rubisco fixes CO2. Its lesser-known side job is supplying pyruvate in the chloroplast, an observation that solves a long-standing paradox of central metabolism. #PlantScience
Reposted by Oliver Mueller-Cajar
itaiyanai.bsky.social
Doing good science is 90% finding a science buddy to constantly talk to about the project.
Reposted by Oliver Mueller-Cajar
alexholehouse.bsky.social
BONUS! If IDPs are your jam, check out an ever-expanding starter pack!
go.bsky.app/J23B51L
Reposted by Oliver Mueller-Cajar
rnadavid.bsky.social
Biomolecular condensate starter pack!

Trying to compile & to bring together biomolecular condensate enthusiasts & critics!

Please join this non-exhaustive (sorry!) collection & just ping me for addition.

#condensates, #phaseseparation, #granules, #IDPs

go.bsky.app/NFqmffa
Reposted by Oliver Mueller-Cajar
chenxinli2.bsky.social
I have a YouTube playlist (10 videos) for #MolecularBiology for my undergrad interns in the lab.

www.youtube.com/playlist?lis...

I usually have my interns watch these videos to get introduced to the basic concepts before I go show them how to in the lab.
A screenshot of first 5 videos of a molecular biology YouTube Playlist: 1) PCR, 2) Gel, 3) Restriction Enzymes, 4) Plasmid, 5) Gibson assembly.
omc111.bsky.social
Nice, would be interesting to see whether RbcL is identical between clones or has diffused in sequence space given massive changes in CO2 concentration since the seed germinated..
Reposted by Oliver Mueller-Cajar
sethabramson.bsky.social
I learned some stuff about Bluesky I did not know by reading this.

Maybe worth passing it on to others so we can all start getting the full benefit of the 🦋.
Here’s some cool stuff you can do with Bluesky
It’s not just an Alf pics repository.
www.theverge.com
Reposted by Oliver Mueller-Cajar
somssich.bsky.social
Yup, the Plant Science Starter Pack has been doing an amazing job. 👌

go.bsky.app/8Zfmwf7
Reposted by Oliver Mueller-Cajar
hikemaydon.bsky.social
Here is a starter to a starter pack for the Aus plant science community. Let’s rebuild. #plantscience

Let me know if you want to be added. Help me find more.
go.bsky.app/AiLTKHH
Reposted by Oliver Mueller-Cajar
rborza.bsky.social
⚠️THREAD OF ALL SCIENCE-RELATED STARTER PACKS! ⚠️

🔄Share to help people finding its topic/field

- STRUCTURAL BIOLOGY

Structural Biology 1: bsky.app/starter-pack...
Structural Biology 2: bsky.app/starter-pack...
Crystallography: bsky.app/starter-pack...
Synchrotron&CryoEM: bsky.app/starter-pack...
omc111.bsky.social
I have a PhD scholarship available for a student to join my group at NTU Singapore in the January 2025 intake. The student will work on a project related to the cellular biochemistry of the diatom pyrenoid. Here is our first paper on the topic: www.pnas.org/doi/abs/10.1...
A linker protein from a red-type pyrenoid phase separates with Rubisco via oligomerizing sticker motifs | PNAS
The slow kinetics and poor substrate specificity of the key photosynthetic CO2-fixing enzyme Rubisco have prompted the repeated evolution of Rubisc...
www.pnas.org
omc111.bsky.social
I love the periodic articles about chilly weather in Singapore. Some days we will have to deal with 23 degrees Celsius..