RD PascualMarqui
@pascualmarqui.bsky.social
KEY Inst Brain-Mind Research @UniZurich
neuroscience imaging connectivity EEG MEG oscillations
+LORETA+
Lagged Coherence/PhaseSynch
Multivar/HiOrder InfoFlow
https://scholar.google.com/scholar?q=pascual-marqui
https://www.uzh.ch/keyinst/
neuroscience imaging connectivity EEG MEG oscillations
+LORETA+
Lagged Coherence/PhaseSynch
Multivar/HiOrder InfoFlow
https://scholar.google.com/scholar?q=pascual-marqui
https://www.uzh.ch/keyinst/
Pinned
Preprint: Equations/generalizations for TC, DTC, RSI, O-information, and TSE-complexity for multivar real/cmplx data. How “connections” contribute to system inf measures.
Helpful comments and reports on errors are appreciated.
arXiv: 2025-07-11
doi.org/10.48550/arXiv.2507.08773
Helpful comments and reports on errors are appreciated.
arXiv: 2025-07-11
doi.org/10.48550/arXiv.2507.08773
Reposted by RD PascualMarqui
Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity - Nature Neuroscience
The authors develop a neural probe with over 1,000 light emitters arranged along its length and circumference, enabling panoramic 3D optical stimulation across large brain volumes.
www.nature.com
November 24, 2025 at 9:29 PM
Laser-engineered PRIME fiber for panoramic reconfigurable control of neural activity
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by RD PascualMarqui
Our team just released a comprehensive and accessible review of Signed Networks — two years in the making! Theory, methods, applications, all in one place. Feedback welcome.
arxiv.org/abs/2511.17247
arxiv.org/abs/2511.17247
Signed Networks: theory, methods, and applications
Signed networks provide a principled framework for representing systems in which interactions are not merely present or absent but qualitatively distinct: friendly or antagonistic, supportive or confl...
arxiv.org
November 24, 2025 at 10:08 AM
Our team just released a comprehensive and accessible review of Signed Networks — two years in the making! Theory, methods, applications, all in one place. Feedback welcome.
arxiv.org/abs/2511.17247
arxiv.org/abs/2511.17247
Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation url: academic.oup.com/brain/articl...
Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation
One third of stroke survivors experience vision loss. Raffin et al. present a non-invasive brain stimulation technique targeting visual pathways and show t
academic.oup.com
November 21, 2025 at 5:52 PM
Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation url: academic.oup.com/brain/articl...
Tracking EEG Thalamic and Cortical Focal Brain Activity using Standardized Kalman Filtering with Kinematics Modeling: Veikka Piispa, Dilshanie Prasikala, Joonas Lahtinen, Alexandra Koulouri, Sampsa Pursiainen.
arXiv:2511.10877
doi.org/10.48550/arX...
14 Nov 2025
arXiv:2511.10877
doi.org/10.48550/arX...
14 Nov 2025
November 21, 2025 at 5:51 PM
Tracking EEG Thalamic and Cortical Focal Brain Activity using Standardized Kalman Filtering with Kinematics Modeling: Veikka Piispa, Dilshanie Prasikala, Joonas Lahtinen, Alexandra Koulouri, Sampsa Pursiainen.
arXiv:2511.10877
doi.org/10.48550/arX...
14 Nov 2025
arXiv:2511.10877
doi.org/10.48550/arX...
14 Nov 2025
Reposted by RD PascualMarqui
New preprint: "Identifying statistical indicators of temporal asymmetry using a data-driven approach"
arxiv.org/abs/2511.15991
_Can we statistically distinguish the forward- versus reverse-time dynamics of a system from a finite time series?_
arxiv.org/abs/2511.15991
_Can we statistically distinguish the forward- versus reverse-time dynamics of a system from a finite time series?_
November 21, 2025 at 3:26 AM
New preprint: "Identifying statistical indicators of temporal asymmetry using a data-driven approach"
arxiv.org/abs/2511.15991
_Can we statistically distinguish the forward- versus reverse-time dynamics of a system from a finite time series?_
arxiv.org/abs/2511.15991
_Can we statistically distinguish the forward- versus reverse-time dynamics of a system from a finite time series?_
Reposted by RD PascualMarqui
🚨New publication!
I am extremely happy to share this new review article in elife on #Traveling_Waves!
@erc.europa.eu
@upcite.bsky.social
elifesciences.org/articles/106...
I am extremely happy to share this new review article in elife on #Traveling_Waves!
@erc.europa.eu
@upcite.bsky.social
elifesciences.org/articles/106...
Traveling waves across scales: Different mechanisms but same canonical computation?
The review proposes a novel mechanistic distinction between first- and second-order traveling waves that subserves a same canonical computation by ordering neuronal processing to impose a computationa...
elifesciences.org
November 19, 2025 at 3:54 PM
🚨New publication!
I am extremely happy to share this new review article in elife on #Traveling_Waves!
@erc.europa.eu
@upcite.bsky.social
elifesciences.org/articles/106...
I am extremely happy to share this new review article in elife on #Traveling_Waves!
@erc.europa.eu
@upcite.bsky.social
elifesciences.org/articles/106...
Anxious vision: Trait-like visual cortical hyperactivity in trait anxiety
Zhaohan Wu, Yuqi You, Joshua A. Brown, Raymond J Dolan, Wen Li
bioRxiv 2025.11.17.688929;
doi: doi.org/10.1101/2025...
#EEG #Neuroscience #Neuroimaging
Zhaohan Wu, Yuqi You, Joshua A. Brown, Raymond J Dolan, Wen Li
bioRxiv 2025.11.17.688929;
doi: doi.org/10.1101/2025...
#EEG #Neuroscience #Neuroimaging
November 18, 2025 at 9:49 PM
Anxious vision: Trait-like visual cortical hyperactivity in trait anxiety
Zhaohan Wu, Yuqi You, Joshua A. Brown, Raymond J Dolan, Wen Li
bioRxiv 2025.11.17.688929;
doi: doi.org/10.1101/2025...
#EEG #Neuroscience #Neuroimaging
Zhaohan Wu, Yuqi You, Joshua A. Brown, Raymond J Dolan, Wen Li
bioRxiv 2025.11.17.688929;
doi: doi.org/10.1101/2025...
#EEG #Neuroscience #Neuroimaging
Reposted by RD PascualMarqui
New putative biomarkers for depression. Describing ephaptic effects.
Ephaptic coupling and power fluctuations in depression https://www.biorxiv.org/content/10.1101/2025.11.15.688471v1
November 17, 2025 at 12:18 PM
New putative biomarkers for depression. Describing ephaptic effects.
Ephaptic coupling and power fluctuations in depression
Dimitrios Pinotsis, Sankaraleengam Alagapan, Parisa Sarikhani, Tanya Nauvel, Christopher Rozell, Helen Mayberg
bioRxiv 2025.11.15.688471; doi: doi.org/10.1101/2025...
Dimitrios Pinotsis, Sankaraleengam Alagapan, Parisa Sarikhani, Tanya Nauvel, Christopher Rozell, Helen Mayberg
bioRxiv 2025.11.15.688471; doi: doi.org/10.1101/2025...
November 17, 2025 at 6:38 AM
Ephaptic coupling and power fluctuations in depression
Dimitrios Pinotsis, Sankaraleengam Alagapan, Parisa Sarikhani, Tanya Nauvel, Christopher Rozell, Helen Mayberg
bioRxiv 2025.11.15.688471; doi: doi.org/10.1101/2025...
Dimitrios Pinotsis, Sankaraleengam Alagapan, Parisa Sarikhani, Tanya Nauvel, Christopher Rozell, Helen Mayberg
bioRxiv 2025.11.15.688471; doi: doi.org/10.1101/2025...
Reposted by RD PascualMarqui
Time, space, memory and brain–body rhythms — a Perspective by György Buzsáki
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Time, space, memory and brain–body rhythms - Nature Reviews Neuroscience
Understanding how the brain represents experienced time and how representations of space and time are integrated to form episodic memories has been a goal of much neuroscientific research. In this Per...
www.nature.com
November 13, 2025 at 11:43 AM
Time, space, memory and brain–body rhythms — a Perspective by György Buzsáki
#neuroscience #neuroskyence
www.nature.com/articles/s41...
#neuroscience #neuroskyence
www.nature.com/articles/s41...
Reposted by RD PascualMarqui
Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Prediction of neural activity in connectome-constrained recurrent networks - Nature Neuroscience
The authors show that connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictio...
www.nature.com
November 10, 2025 at 10:12 PM
Connectome datasets alone are generally not sufficient to predict neural activity. However, pairing connectivity information with neural recordings can produce accurate predictions of activity in unrecorded neurons
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by RD PascualMarqui
This NeurIPS workshop claims that LLMs "provide an important foundation for exploring human cognition, emotion, and social interaction"
This is flawed logic, as @lmesseri.bsky.social and I argue here:
www.sciencedirect.com/science/arti...
This is flawed logic, as @lmesseri.bsky.social and I argue here:
www.sciencedirect.com/science/arti...
November 9, 2025 at 3:23 PM
This NeurIPS workshop claims that LLMs "provide an important foundation for exploring human cognition, emotion, and social interaction"
This is flawed logic, as @lmesseri.bsky.social and I argue here:
www.sciencedirect.com/science/arti...
This is flawed logic, as @lmesseri.bsky.social and I argue here:
www.sciencedirect.com/science/arti...
Reposted by RD PascualMarqui
📣New paper alert!📣
Ever wonder how to model the temporal generalization task? Interested in cross-modal comparisons? Our paper (w/ the magnificent Nir Ofir!) is for you! @timingresforum.bsky.social this could make for a solid post-conference decompression read
link.springer.com/article/10.3...
Ever wonder how to model the temporal generalization task? Interested in cross-modal comparisons? Our paper (w/ the magnificent Nir Ofir!) is for you! @timingresforum.bsky.social this could make for a solid post-conference decompression read
link.springer.com/article/10.3...
A drift-diffusion model of temporal generalization outperforms existing models and captures modality differences and learning effects - Behavior Research Methods
Multiple systems in the brain track the passage of time and can adapt their activity to temporal requirements. While the neural implementation of timing varies widely between neural substrates and beh...
link.springer.com
November 6, 2025 at 4:30 AM
📣New paper alert!📣
Ever wonder how to model the temporal generalization task? Interested in cross-modal comparisons? Our paper (w/ the magnificent Nir Ofir!) is for you! @timingresforum.bsky.social this could make for a solid post-conference decompression read
link.springer.com/article/10.3...
Ever wonder how to model the temporal generalization task? Interested in cross-modal comparisons? Our paper (w/ the magnificent Nir Ofir!) is for you! @timingresforum.bsky.social this could make for a solid post-conference decompression read
link.springer.com/article/10.3...
Reposted by RD PascualMarqui
ICYMI @ohbmofficial.bsky.social 2025 keynotes are now online! Here's mine: "Towards a universal taxonomy of functional brain networks" 🧠 www.youtube.com/watch?v=ZW9J...
OHBM 2025 | Keynote | Lucina Uddin | Towards a universal taxonomy of functional brain networks
YouTube video by Organization for Human Brain Mapping
www.youtube.com
November 5, 2025 at 7:21 PM
ICYMI @ohbmofficial.bsky.social 2025 keynotes are now online! Here's mine: "Towards a universal taxonomy of functional brain networks" 🧠 www.youtube.com/watch?v=ZW9J...
Neural Encoding through Hierarchical Amplitude Modulation
Giulio Ruffini
bioRxiv 2025.11.03.686310
doi.org/10.1101/2025...
Its log-uniform distribution yields a 1/f global spectral profile and 1/f^α sideband "aperiodic" component, with the slope determined by modulation depth and band ratio.
Giulio Ruffini
bioRxiv 2025.11.03.686310
doi.org/10.1101/2025...
Its log-uniform distribution yields a 1/f global spectral profile and 1/f^α sideband "aperiodic" component, with the slope determined by modulation depth and band ratio.
Neural Encoding through Hierarchical Amplitude Modulation
Hierarchical encoding is a structural element of the Free Energy Principle and related information-centric accounts of brain function, but a concrete circuit-level mechanism for it remains elusive. He...
doi.org
November 5, 2025 at 5:52 AM
Neural Encoding through Hierarchical Amplitude Modulation
Giulio Ruffini
bioRxiv 2025.11.03.686310
doi.org/10.1101/2025...
Its log-uniform distribution yields a 1/f global spectral profile and 1/f^α sideband "aperiodic" component, with the slope determined by modulation depth and band ratio.
Giulio Ruffini
bioRxiv 2025.11.03.686310
doi.org/10.1101/2025...
Its log-uniform distribution yields a 1/f global spectral profile and 1/f^α sideband "aperiodic" component, with the slope determined by modulation depth and band ratio.
Reposted by RD PascualMarqui
More on the link brain-heart axis and sensorimotor function, relevant for BCI research 🤖: Different bodily rhythms are coupled with cortical regions at rest. Here we show that motor imagery triggers a decoupling of cardiac dynamics with motor cortex functional connectivity 🧠🫀 doi.org/10.1101/2025...
Imagined movement increases the segregation of brain-heart networks
Understanding the mechanisms of motor imagery, the mental simulation of movement without execution, is key for the development of neurotechnologies. For instance, for detecting covert motor intent in ...
doi.org
November 4, 2025 at 1:28 PM
More on the link brain-heart axis and sensorimotor function, relevant for BCI research 🤖: Different bodily rhythms are coupled with cortical regions at rest. Here we show that motor imagery triggers a decoupling of cardiac dynamics with motor cortex functional connectivity 🧠🫀 doi.org/10.1101/2025...
Reposted by RD PascualMarqui
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
November 3, 2025 at 1:55 PM
Nature suggests you use their "Manuscript Adviser" bot to get advice before submitting
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
I uploaded the classic Watson & Crick paper about DNA structure, and the Adviser had this to say about one of the greatest paper endings of the century:
Reposted by RD PascualMarqui
Combo of two papers on partial information rate decomposition now out!
journals.aps.org/prl/abstract...
journals.aps.org/pre/abstract...
Mini thread below 👇
journals.aps.org/prl/abstract...
journals.aps.org/pre/abstract...
Mini thread below 👇
Partial Information Rate Decomposition
Partial information decomposition (PID) is a principled and flexible method to unveil complex high-order interactions in multiunit network systems. Though being defined exclusively for random variable...
journals.aps.org
October 30, 2025 at 10:12 AM
Combo of two papers on partial information rate decomposition now out!
journals.aps.org/prl/abstract...
journals.aps.org/pre/abstract...
Mini thread below 👇
journals.aps.org/prl/abstract...
journals.aps.org/pre/abstract...
Mini thread below 👇
Reposted by RD PascualMarqui
That merely being “under review” by a Nature family journal is offered as a quality proxy for a paper is a tragic illustration of the extent to which academia is addicted to brands and outsources evaluation
October 25, 2025 at 6:37 PM
That merely being “under review” by a Nature family journal is offered as a quality proxy for a paper is a tragic illustration of the extent to which academia is addicted to brands and outsources evaluation
Reposted by RD PascualMarqui
BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...
October 22, 2025 at 12:41 AM
BOLD signal changes can oppose oxygen metabolism across the human cortex | bioRxiv www.biorxiv.org/content/10.1...
very interesting paper if all math correct: much better than traditional cmplx-PCA method for quantifying the presence of travelling and standing waves:
Li, Qu, Yi & Hong: Resolving Whole-Brain Alpha Traveling Waves Across Brain States. NeuroImage October 2025
doi:10.1016/j.neuroimage.2025.121538
Li, Qu, Yi & Hong: Resolving Whole-Brain Alpha Traveling Waves Across Brain States. NeuroImage October 2025
doi:10.1016/j.neuroimage.2025.121538
October 17, 2025 at 8:48 AM
very interesting paper if all math correct: much better than traditional cmplx-PCA method for quantifying the presence of travelling and standing waves:
Li, Qu, Yi & Hong: Resolving Whole-Brain Alpha Traveling Waves Across Brain States. NeuroImage October 2025
doi:10.1016/j.neuroimage.2025.121538
Li, Qu, Yi & Hong: Resolving Whole-Brain Alpha Traveling Waves Across Brain States. NeuroImage October 2025
doi:10.1016/j.neuroimage.2025.121538
Reposted by RD PascualMarqui
I find this paper really confusing. There are several measures (power, coherence, network communication, information based statistical dependencies) which are all measures of the "behavior" of the system, and definitely share similarities. Yet some are considered "mechanisms" underlying the others.
Evaluating oscillatory mechanisms underlying flexible neural communication in the human brain https://www.biorxiv.org/content/10.1101/2025.10.16.682957v1
October 17, 2025 at 7:39 AM
I find this paper really confusing. There are several measures (power, coherence, network communication, information based statistical dependencies) which are all measures of the "behavior" of the system, and definitely share similarities. Yet some are considered "mechanisms" underlying the others.
Reposted by RD PascualMarqui
Colombo et al., Plos Biology, "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans"
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans
Hemispherotomy is a neurosurgical procedure for treating refractory epilepsy by disconnecting a significant portion of the cortex. This study shows that the isolated cortex exhibits EEG patterns resem...
journals.plos.org
October 16, 2025 at 6:13 PM
Colombo et al., Plos Biology, "Hemispherotomy leads to persistent sleep-like slow waves in the isolated cortex of awake humans"
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by RD PascualMarqui
Academia is supposed to be an open environment where people can disagree with each other, but people are happy to keep your work invisible if they disagree with some minor thing. I suspect many rejected papers are perfectly fine and rejection is wasting everyone's time and mental health.
October 15, 2025 at 10:39 AM
Academia is supposed to be an open environment where people can disagree with each other, but people are happy to keep your work invisible if they disagree with some minor thing. I suspect many rejected papers are perfectly fine and rejection is wasting everyone's time and mental health.
Reposted by RD PascualMarqui
Kort Driessen, Fabio Squarcio, Giulio Tononi, Chiara Cirelli
"Induction of cortical ON/OFF periods in awake mice fulfills sleep functions"
doi.org/10.1101/2025...
"Induction of cortical ON/OFF periods in awake mice fulfills sleep functions"
doi.org/10.1101/2025...
Induction of cortical ON/OFF periods in awake mice fulfills sleep functions
Can animals obtain core benefits of sleep while remaining awake? In mammals, slow-wave sleep is characterized by synchronized neuronal activity alternating between ON and OFF periods. Slow-wave activi...
doi.org
October 9, 2025 at 8:52 PM
Kort Driessen, Fabio Squarcio, Giulio Tononi, Chiara Cirelli
"Induction of cortical ON/OFF periods in awake mice fulfills sleep functions"
doi.org/10.1101/2025...
"Induction of cortical ON/OFF periods in awake mice fulfills sleep functions"
doi.org/10.1101/2025...