Perline Demange
@perlinedemange.bsky.social
Postdoctoral fellow at PROMENTA, University of Oslo.
Genetics – Intergenerational Transmission of Inequalities – Mental Health – Education
https://perlinedemange.github.io/
Genetics – Intergenerational Transmission of Inequalities – Mental Health – Education
https://perlinedemange.github.io/
Pinned
And that’s already a wrap for me, thank you all for coming to my poster! @essgn.bsky.social #ESSGN2025
Reposted by Perline Demange
Happy to share our latest study published in PNAS.
Using data from 274,316 French students, we find that lower-SES students are less likely to wait for better university offers, even when waiting would lead to more prestigious or better-fit programs.
www.pnas.org/doi/10.1073/...
Using data from 274,316 French students, we find that lower-SES students are less likely to wait for better university offers, even when waiting would lead to more prestigious or better-fit programs.
www.pnas.org/doi/10.1073/...
Waiting time during admission procedures increases social inequalities in higher education | PNAS
Many domains in life require people to wait to access better outcomes, such as waiting
in line to access prized tickets for a show, waiting to obta...
www.pnas.org
November 26, 2025 at 9:27 AM
Happy to share our latest study published in PNAS.
Using data from 274,316 French students, we find that lower-SES students are less likely to wait for better university offers, even when waiting would lead to more prestigious or better-fit programs.
www.pnas.org/doi/10.1073/...
Using data from 274,316 French students, we find that lower-SES students are less likely to wait for better university offers, even when waiting would lead to more prestigious or better-fit programs.
www.pnas.org/doi/10.1073/...
Reposted by Perline Demange
This paper clearly articulates what is, in my opinion, one of the major ethical problems with polygenic embryo testing companies--that they are *companies* that sell health as a private commodity. from @gaiaghirardi.bsky.social & @arnovanhootegem.bsky.social
www.fertstert.org/news-do/embr...
www.fertstert.org/news-do/embr...
Embryo selection based on polygenic prediction risks reinforcing social inequality
The rise of companies offering embryo selection based on genetic testing has triggered heated debate about ethical acceptability, as well as the accuracy and scientific validity of these techniques. W...
www.fertstert.org
November 13, 2025 at 2:35 PM
This paper clearly articulates what is, in my opinion, one of the major ethical problems with polygenic embryo testing companies--that they are *companies* that sell health as a private commodity. from @gaiaghirardi.bsky.social & @arnovanhootegem.bsky.social
www.fertstert.org/news-do/embr...
www.fertstert.org/news-do/embr...
"Offering genetic predictions for embryos to improve health outcomes latches onto a privatization logic that does exactly the opposite and hence erodes a system based on social equality and solidarity."
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
There’s a new kid in town!
Companies are now selling IVF and embryo selection based on genetic testing for traits related to health and even intelligence.
We outline methodological and ethical concerns, and warn against risks for social inequality.
With the fantastic @gaiaghirardi.bsky.social
Companies are now selling IVF and embryo selection based on genetic testing for traits related to health and even intelligence.
We outline methodological and ethical concerns, and warn against risks for social inequality.
With the fantastic @gaiaghirardi.bsky.social
Embryo selection based on polygenic prediction risks reinforcing social inequality
The rise of companies offering embryo selection based on genetic testing has triggered heated debate about ethical acceptability, as well as the accuracy and scientific validity of these techniques. W...
www.fertstert.org
November 13, 2025 at 1:47 PM
"Offering genetic predictions for embryos to improve health outcomes latches onto a privatization logic that does exactly the opposite and hence erodes a system based on social equality and solidarity."
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
Thank you @arnovanhootegem.bsky.social @gaiaghirardi.bsky.social for such an important piece!
New paper by Rosa Cheesman and co: GWAS of fields of education and phenotypic annotations 🥳👇
1/ 🚨New paper in Nature Genetics
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic factors are associated with the educational fields people study, from arts to engineering.
Article: www.nature.com/articles/s41...
FAQ: www.thehastingscenter.org/genomic-find...
Genetic associations with educational fields - Nature Genetics
Genome-wide analyses of 10 educational fields identify 17 associated loci. Analysis of genetic clustering across specializations identifies two key dimensions that show genetic overlap with personalit...
www.nature.com
November 6, 2025 at 10:23 AM
New paper by Rosa Cheesman and co: GWAS of fields of education and phenotypic annotations 🥳👇
Reposted by Perline Demange
Excited to share this work led by @cktamnes.bsky.social (and featuring many colleagues from PROMENTA at @unioslo-svfak.bsky.social) exploring the links between psychological wellbeing and illbeing across biological, developmental, societal and intervention perspectives
The nature of the relation between mental well-being and ill-being
www.nature.com/articles/s41...
www.nature.com/articles/s41...
The nature of the relation between mental well-being and ill-being - Nature Human Behaviour
Tamnes et al. explore the complex relationship between ill-being—including mental and behavioural disorders—and mental well-being.
www.nature.com
October 16, 2025 at 3:55 PM
Excited to share this work led by @cktamnes.bsky.social (and featuring many colleagues from PROMENTA at @unioslo-svfak.bsky.social) exploring the links between psychological wellbeing and illbeing across biological, developmental, societal and intervention perspectives
Reposted by Perline Demange
Interdisciplinary paper with @paulhufe.net Astrid Sandsør and Nicolai Borgen now out in PNAS!
www.pnas.org/doi/epdf/10....
Causal evidence of gene-environment interaction for reading test scores based on:
🧬 Exogenous within-family genetic differences
🏫 Exogenous variation in school value added
www.pnas.org/doi/epdf/10....
Causal evidence of gene-environment interaction for reading test scores based on:
🧬 Exogenous within-family genetic differences
🏫 Exogenous variation in school value added
The genetic lottery goes to school: Better schools compensate for the effects of students’ genetic differences
www.pnas.org
October 28, 2025 at 11:25 AM
Interdisciplinary paper with @paulhufe.net Astrid Sandsør and Nicolai Borgen now out in PNAS!
www.pnas.org/doi/epdf/10....
Causal evidence of gene-environment interaction for reading test scores based on:
🧬 Exogenous within-family genetic differences
🏫 Exogenous variation in school value added
www.pnas.org/doi/epdf/10....
Causal evidence of gene-environment interaction for reading test scores based on:
🧬 Exogenous within-family genetic differences
🏫 Exogenous variation in school value added
Reposted by Perline Demange
Brilliant thread summarising this field - perfect for those in other fields 🙏
🧩Learning to talk & read isn’t just about effort or teaching—it’s shaped by biology, experience & context
🧠Our new review links genetics, neuroscience, psychology & education to show why some children find language or reading easier.
📖 doi.org/10.31234/osf...
🖼️genes→brain→cognition→behaviour 🧵👇
🧠Our new review links genetics, neuroscience, psychology & education to show why some children find language or reading easier.
📖 doi.org/10.31234/osf...
🖼️genes→brain→cognition→behaviour 🧵👇
October 6, 2025 at 10:46 AM
Brilliant thread summarising this field - perfect for those in other fields 🙏
Reposted by Perline Demange
Two birds of a gene - catch Matt Keller's webinar at @uio.no on October 15th. Please share
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
Using structural equation models to estimate direct and indirect genetic effects and assortative mating in trio data
- PROMENTA
Guest lecture by Matt Keller
www.sv.uio.no
October 5, 2025 at 11:11 AM
Two birds of a gene - catch Matt Keller's webinar at @uio.no on October 15th. Please share
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
www.sv.uio.no/promenta/eng...
@ispg.bsky.social @behaviorgenetic.bsky.social @unioslo-svfak.bsky.social @essgn.bsky.social @ibg.colorado.edu
Should we tax the super-rich?
My favorite news show tackles this question this week: www.arte.tv/en/videos/11... (spoiler: the answer is yes)
My favorite news show tackles this question this week: www.arte.tv/en/videos/11... (spoiler: the answer is yes)
ARTE Europe Weekly - Does Europe need a supertax for the super-rich? - Watch the full documentary | ARTE in English
Europe’s super-rich are getting astronomically wealthy, while the squeezed middle and lower classes are being asked to tighten their belts. The French economist Gabriel Zucman has proposed a wealth ta...
www.arte.tv
October 5, 2025 at 8:06 PM
Should we tax the super-rich?
My favorite news show tackles this question this week: www.arte.tv/en/videos/11... (spoiler: the answer is yes)
My favorite news show tackles this question this week: www.arte.tv/en/videos/11... (spoiler: the answer is yes)
Reposted by Perline Demange
Currently attending a conference & our field is quite a bit into fancy modeling, so it’s time to repost this blog post.
Don’t try to squeeze your research question into whatever model is fashionable right now; try to build the right model for your research question.
www.the100.ci/2024/08/27/l...
Don’t try to squeeze your research question into whatever model is fashionable right now; try to build the right model for your research question.
www.the100.ci/2024/08/27/l...
Let’s do statistics the other way around
Summer in Berlin – the perfect time and place to explore the city, take a walk in the Görli, go skinny dipping in the Spree, attend an overcrowded, overheated conference symposium on cross-lagged pane...
www.the100.ci
September 23, 2025 at 4:38 AM
Currently attending a conference & our field is quite a bit into fancy modeling, so it’s time to repost this blog post.
Don’t try to squeeze your research question into whatever model is fashionable right now; try to build the right model for your research question.
www.the100.ci/2024/08/27/l...
Don’t try to squeeze your research question into whatever model is fashionable right now; try to build the right model for your research question.
www.the100.ci/2024/08/27/l...
Reposted by Perline Demange
📢 Appel à communications
Les conférences annuelles des GDR FRESH et RESHAPE auront lieu à Montpellier, les 4–6 nov. 2025.
Thèmes : santé publique & inégalités, climat & santé, evolutionary medicine, + session Varia.
✅ Inscription gratuite → fresh-reshape25.sciencesconf.org
📅 Deadline : 30 sept.
Les conférences annuelles des GDR FRESH et RESHAPE auront lieu à Montpellier, les 4–6 nov. 2025.
Thèmes : santé publique & inégalités, climat & santé, evolutionary medicine, + session Varia.
✅ Inscription gratuite → fresh-reshape25.sciencesconf.org
📅 Deadline : 30 sept.
September 20, 2025 at 11:39 AM
📢 Appel à communications
Les conférences annuelles des GDR FRESH et RESHAPE auront lieu à Montpellier, les 4–6 nov. 2025.
Thèmes : santé publique & inégalités, climat & santé, evolutionary medicine, + session Varia.
✅ Inscription gratuite → fresh-reshape25.sciencesconf.org
📅 Deadline : 30 sept.
Les conférences annuelles des GDR FRESH et RESHAPE auront lieu à Montpellier, les 4–6 nov. 2025.
Thèmes : santé publique & inégalités, climat & santé, evolutionary medicine, + session Varia.
✅ Inscription gratuite → fresh-reshape25.sciencesconf.org
📅 Deadline : 30 sept.
Reposted by Perline Demange
Proud to share our new @nber working paper on how genetics shape the intergenerational transmission of socioeconomic status in the Netherlands. 🧵(1/8)
www.nber.org/papers/w34208
www.nber.org/papers/w34208
A Chip Off the Old Block? Genetics and the Intergenerational Transmission of Socioeconomic Status
Founded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, an...
www.nber.org
September 15, 2025 at 9:41 AM
Proud to share our new @nber working paper on how genetics shape the intergenerational transmission of socioeconomic status in the Netherlands. 🧵(1/8)
www.nber.org/papers/w34208
www.nber.org/papers/w34208
Reposted by Perline Demange
Choosing to go by train/ferry to #Flux2025 I emitted SEVEN times less C02 compared to a plane trip.
Air travel is one of the largest contributors to the carbon footprint of research. Researchers, universities and conferences have the responsabilities to create more sustainable alternatives.
Air travel is one of the largest contributors to the carbon footprint of research. Researchers, universities and conferences have the responsabilities to create more sustainable alternatives.
September 15, 2025 at 10:00 AM
Choosing to go by train/ferry to #Flux2025 I emitted SEVEN times less C02 compared to a plane trip.
Air travel is one of the largest contributors to the carbon footprint of research. Researchers, universities and conferences have the responsabilities to create more sustainable alternatives.
Air travel is one of the largest contributors to the carbon footprint of research. Researchers, universities and conferences have the responsabilities to create more sustainable alternatives.
Reposted by Perline Demange
Brilliant paper by Visscher et al.
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Direct effect of genetic ancestry on complex traits in a Mexican population
Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...
www.medrxiv.org
September 11, 2025 at 5:57 AM
Brilliant paper by Visscher et al.
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Populations differ in traits/disease burden. Are these differences due to genetics?
Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.
1/3
www.medrxiv.org/content/10.1...
Reposted by Perline Demange
This is a helpful article of where Norwegian green politics is at and where it is coming from with insights by @elinlb.bsky.social
www.greeneuropeanjournal.eu/norways-elec...
www.greeneuropeanjournal.eu/norways-elec...
Norway’s Elections: A Fossil Consensus
Could the rise of smaller parties drive Europe’s biggest gas supplier to change course?
www.greeneuropeanjournal.eu
September 8, 2025 at 8:13 AM
This is a helpful article of where Norwegian green politics is at and where it is coming from with insights by @elinlb.bsky.social
www.greeneuropeanjournal.eu/norways-elec...
www.greeneuropeanjournal.eu/norways-elec...
Reposted by Perline Demange
To engage people on the problem of wealth inequality, we should focus on the “unfair influence” wielded by those at the top, write @michaelvaughan.bsky.social, @wealtherty.bsky.social & Annalena Oppel, even if that causes outrage.
@jrf-uk.bsky.social
🔗 buff.ly/GAf0Es5
@jrf-uk.bsky.social
🔗 buff.ly/GAf0Es5
It’s time to face up to power in the debate about wealth inequality
When discussing wealth inequality, the “unfair influence” framing fares best at driving support for redistributive measures. But does it come with hidden costs?
buff.ly
August 19, 2025 at 9:14 AM
To engage people on the problem of wealth inequality, we should focus on the “unfair influence” wielded by those at the top, write @michaelvaughan.bsky.social, @wealtherty.bsky.social & Annalena Oppel, even if that causes outrage.
@jrf-uk.bsky.social
🔗 buff.ly/GAf0Es5
@jrf-uk.bsky.social
🔗 buff.ly/GAf0Es5
Reposted by Perline Demange
New paper! 📜 In nearly 50,000 individuals randomly sampled from the general population, we apply a symptom-specific perspective to examine which anxiety and depressive symptoms are most strongly associated with various aspects of financial adversity
doi.org/10.1016/j.ss...
doi.org/10.1016/j.ss...
August 17, 2025 at 2:34 PM
New paper! 📜 In nearly 50,000 individuals randomly sampled from the general population, we apply a symptom-specific perspective to examine which anxiety and depressive symptoms are most strongly associated with various aspects of financial adversity
doi.org/10.1016/j.ss...
doi.org/10.1016/j.ss...
This is the most interesting opinion piece I have read on the topic of polygenic embryo screening!
The "having" and "doing" of motherhood, the concrete practicalities of IVF, the blur between traits and diseases, etc.
Highly recommended reading.
The "having" and "doing" of motherhood, the concrete practicalities of IVF, the blur between traits and diseases, etc.
Highly recommended reading.
August 12, 2025 at 3:35 PM
This is the most interesting opinion piece I have read on the topic of polygenic embryo screening!
The "having" and "doing" of motherhood, the concrete practicalities of IVF, the blur between traits and diseases, etc.
Highly recommended reading.
The "having" and "doing" of motherhood, the concrete practicalities of IVF, the blur between traits and diseases, etc.
Highly recommended reading.
Reposted by Perline Demange
I could not resist...
August 9, 2025 at 8:33 PM
I could not resist...
"Sure, at some level everyone has a right to whatever knowledge is out there about their own genome, but dissemination of that knowledge should be based on something more than a toxic combination of libertarianism, greed, and ignorance."
New blog post: The New Eugenics Companies
(Oops, I meant to say generational health and embryo selection)
(Oops, I meant to say generational health and embryo selection)
The New Eugenics Companies
Oops, I meant to say generational health and embryo selection
ericturkheimer.substack.com
August 10, 2025 at 5:52 PM
"Sure, at some level everyone has a right to whatever knowledge is out there about their own genome, but dissemination of that knowledge should be based on something more than a toxic combination of libertarianism, greed, and ignorance."
How much do people know and understand what their administrative and health data is used for?
Another story of consent for genetic data use this week.
Another story of consent for genetic data use this week.
The iPSYCH study represents a unique example to understand the ethical and legal challenges of using existing samples/data for health research. A thread 🧵
www.science.org/content/arti...
www.science.org/content/arti...
Blood taken from Danish babies ended up in huge genetic study—without consent
The iPsych project, which investigates the genetics of psychiatric disorders, has sent 140,000 opt-out notices amid backlash
www.science.org
August 6, 2025 at 10:21 AM
How much do people know and understand what their administrative and health data is used for?
Another story of consent for genetic data use this week.
Another story of consent for genetic data use this week.
Reposted by Perline Demange
A few thoughts on Herasight, the new embryo selection company. First, their whitepaper (drive.google.com/file/d/1EpFi...) implies that competitors like Nucleus have been marketing and selling grossly erroneous risk estimates. This is shocking if true! 🧵
August 2, 2025 at 2:38 PM
A few thoughts on Herasight, the new embryo selection company. First, their whitepaper (drive.google.com/file/d/1EpFi...) implies that competitors like Nucleus have been marketing and selling grossly erroneous risk estimates. This is shocking if true! 🧵
Must-read for anyone considering Mendelian Imputation to increase their genetic sample.
Is the potential benefit really outweighing the risks?
Is the potential benefit really outweighing the risks?
New pre-print online: Imputing parental genotypes through Mendelian Imputation: Ethical and Legal Considerations
osf.io/preprints/ps...
osf.io/preprints/ps...
OSF
osf.io
August 4, 2025 at 11:03 AM
Must-read for anyone considering Mendelian Imputation to increase their genetic sample.
Is the potential benefit really outweighing the risks?
Is the potential benefit really outweighing the risks?
Reposted by Perline Demange
Poetry collection is going well thanks for asking
July 24, 2025 at 8:35 AM
Poetry collection is going well thanks for asking