Perline Demange
@perlinedemange.bsky.social
920 followers 810 following 130 posts
Postdoctoral fellow at PROMENTA, University of Oslo. Genetics – Intergenerational Transmission of Inequalities – Mental Health – Education https://perlinedemange.github.io/
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perlinedemange.bsky.social
And that’s already a wrap for me, thank you all for coming to my poster! @essgn.bsky.social #ESSGN2025
perlinedemange.bsky.social
So your meta-analysis does not find publication bias?
perlinedemange.bsky.social
Feeling seen here as I am scrolling Bsky during my break from writing a review of PGIxE methods and challenges, exactly because of this fear 😏 Let's hope we can salvage the field.
Reposted by Perline Demange
sirileknes.bsky.social
Brilliant thread summarising this field - perfect for those in other fields 🙏
drelsje.bsky.social
🧩Learning to talk & read isn’t just about effort or teaching—it’s shaped by biology, experience & context

🧠Our new review links genetics, neuroscience, psychology & education to show why some children find language or reading easier.

📖 doi.org/10.31234/osf...

🖼️genes→brain→cognition→behaviour 🧵👇
Figure 2 in the review: Levels of analysis from genes and brain systems to cognition and behaviour.
The child both influences and is influenced by parents through genetically shaped interactions, and by the wider school and social environment.
Figure design by Neil Usher.
Figure from this review paper: https://doi.org/10.31234/osf.io/w23yz_v1
Reposted by Perline Demange
dingdingpeng.the100.ci
Currently attending a conference & our field is quite a bit into fancy modeling, so it’s time to repost this blog post.

Don’t try to squeeze your research question into whatever model is fashionable right now; try to build the right model for your research question.

www.the100.ci/2024/08/27/l...
Let’s do statistics the other way around
Summer in Berlin – the perfect time and place to explore the city, take a walk in the Görli, go skinny dipping in the Spree, attend an overcrowded, overheated conference symposium on cross-lagged pane...
www.the100.ci
Reposted by Perline Demange
monajoly.bsky.social
📢 Appel à communications
Les conférences annuelles des GDR FRESH et RESHAPE auront lieu à Montpellier, les 4–6 nov. 2025.

Thèmes : santé publique & inégalités, climat & santé, evolutionary medicine, + session Varia.

✅ Inscription gratuite → fresh-reshape25.sciencesconf.org
📅 Deadline : 30 sept.
Reposted by Perline Demange
leacmichel.bsky.social
Choosing to go by train/ferry to #Flux2025 I emitted SEVEN times less C02 compared to a plane trip.

Air travel is one of the largest contributors to the carbon footprint of research. Researchers, universities and conferences have the responsabilities to create more sustainable alternatives.
Reposted by Perline Demange
shaicarmi.bsky.social
Brilliant paper by Visscher et al.

Populations differ in traits/disease burden. Are these differences due to genetics?

Comparing single variants or polygenic scores between populations is biased due to environmental confounders correlated with the variants.

1/3

www.medrxiv.org/content/10.1...
Direct effect of genetic ancestry on complex traits in a Mexican population
Human populations differ in disease prevalences and in average values of phenotypes, but the extent to which differences are caused by genetic or environmental factors is unknown for most complex trai...
www.medrxiv.org
Reposted by Perline Demange
ludvigdb.bsky.social
New paper! 📜 In nearly 50,000 individuals randomly sampled from the general population, we apply a symptom-specific perspective to examine which anxiety and depressive symptoms are most strongly associated with various aspects of financial adversity

doi.org/10.1016/j.ss...
perlinedemange.bsky.social
This is the most interesting opinion piece I have read on the topic of polygenic embryo screening!
The "having" and "doing" of motherhood, the concrete practicalities of IVF, the blur between traits and diseases, etc.

Highly recommended reading.
kph3k.bsky.social
I wrote about my recent experiences taking care of my 3-year-old, Sheila Heti's "Motherhood", and the discourse around polygenic embryo selection: kathrynpaigeharden.substack.com/p/openness-t...
Openness to Risk in Motherhood and "Motherhood"
Some Thoughts Related to Polygenic Embryo Screening
kathrynpaigeharden.substack.com
perlinedemange.bsky.social
I think one key benefit of having coauthors is their enthusiasm for the paper when after a while I am quite likely to think it is worthless and probably incorrect. So I’m sure this feeling is a side effect of a solo paper and it will in fact be very interesting!
Reposted by Perline Demange
perlinedemange.bsky.social
"Sure, at some level everyone has a right to whatever knowledge is out there about their own genome, but dissemination of that knowledge should be based on something more than a toxic combination of libertarianism, greed, and ignorance."
ent3c.bsky.social
New blog post: The New Eugenics Companies
(Oops, I meant to say generational health and embryo selection)
The New Eugenics Companies
Oops, I meant to say generational health and embryo selection
ericturkheimer.substack.com
perlinedemange.bsky.social
How much do people know and understand what their administrative and health data is used for?
Another story of consent for genetic data use this week.
Reposted by Perline Demange
sashagusevposts.bsky.social
A few thoughts on Herasight, the new embryo selection company. First, their whitepaper (drive.google.com/file/d/1EpFi...) implies that competitors like Nucleus have been marketing and selling grossly erroneous risk estimates. This is shocking if true! 🧵
perlinedemange.bsky.social
Must-read for anyone considering Mendelian Imputation to increase their genetic sample.
Is the potential benefit really outweighing the risks?
margotvdweijer.bsky.social
New pre-print online: Imputing parental genotypes through Mendelian Imputation: Ethical and Legal Considerations
osf.io/preprints/ps...
OSF
osf.io
Reposted by Perline Demange
pengzell.bsky.social
Poetry collection is going well thanks for asking
Mock up of a pamphlet with silly academic poems in the form of bluesky posts
perlinedemange.bsky.social
I once reviewed a document that still contained co-authors comments and questions left unanswered… at least I could just copy-paste for my report 🙃