Rahul Ganatra
@rbganatra.bsky.social
380 followers 220 following 69 posts
Medical Attending and Director of CME at VA Boston | Critical Appraisal enthusiast @thecurbsiders.bsky.social & Journal Watch. Easily fascinated. Views mine, but I'll share.
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rbganatra.bsky.social
Ooh I've never considered that aspect of it before. That sounds deserving of its own story. I bet there's all kinds of therapies that just got grandfathered in
rbganatra.bsky.social
Serum ammonia level determination in known cirrhosis

Universal secondary SBP prophylaxis (caveat, guidelines still recommend this)

Universal Abx prophylaxis after UGIB in cirrhosis (same caveat)

Is docusate high-stakes enough? I know it's true but its so blah
rbganatra.bsky.social
It feels like critical appraisal is about to have a bit of a moment... let's do it right, people!
Reposted by Rahul Ganatra
propublica.org
One insurance denial for Teressa's husband stated, “your newborn does not meet the criteria for coverage.”

“This is when I really start to think they’re just denying,” she recalled. “They’re not even looking. They’re just ‘deny, deny, deny.’”

➡️ Full story: www.propublica.org/article/ment...
Screenshot of article excerpt: Highmark refused to pay for the emergency medical treatment for the colon infection. In a bizarre twist, that denial letter listed her husband as the patient but made reference to the care of a newborn, not that of a 52-year-old man having a mental health crisis.

“It was determined,” the letter said, “that your newborn does not meet the criteria for coverage of an inpatient hospital admission.”

“This is when I really start to think they’re just denying,” she recalled. “They’re not even looking. They’re just ‘deny, deny, deny.’”
rbganatra.bsky.social
Thanks so much, Moises! We loved having you and I personally learned a lot!
rbganatra.bsky.social
Question for folks in medicine and science:

What are some of the best invited editorials you have ever read?

What made them so good?
rbganatra.bsky.social
Lots of gold in this list!
hswapnil.medsky.social
💯 this

Forget the introduction
Never read the discussion

Make up your own mind

www.nephjc.com/news/10steps
Reposted by Rahul Ganatra
thecurbsiders.bsky.social
🥞 #496 Hotcakes are here! 🩺
www.thecurbsiders.com

We’re diving into:
🌿 CBD-induced liver injury
💉 IV iron for HFrEF
🛏️ Bedtime BP meds
✋ Carpal Tunnel & RA
❤️ FDA approval of finerenone for HFpEF

✨ featuring @paulnwilliams.bsky.social @rbganatra.bsky.social, Dr. Nora Taranto, Dr. Matthew Watto
Reposted by Rahul Ganatra
rebeccasear.bsky.social
“The study authors asked GPT 4o-mini to evaluate the quality of 217 papers. The tool didn’t mention in any of the reports that the papers being analyzed had been retracted or had validity issues.

In 190 cases, GPT described the papers as world leading, internationally excellent, or close to that”
ChatGPT tends to ignore retractions on scientific papers
Study finds the chatbot doesn’t acknowledge concerns with problematic studies
cen.acs.org
rbganatra.bsky.social
Congratulations, Joel!! Well-deserved!
rbganatra.bsky.social
I have definitely made arguments that, in retrospect, were not persuasive enough. Someone telling me why they weren't persuaded would be very useful!

(I thought that was a more constructive response than "I'm not convinced! 😂)
Reposted by Rahul Ganatra
maddow.msnbc.com
"Health Secretary Robert F. Kennedy Jr, who oversees the CDC, did not make a statement the day of the shooting.

Late the following morning, more than 30 minutes after posting photos of fishing with his family, Kennedy posted condolences on his official X account..."

www.nytimes.com/2025/08/09/u...
After Years of Anger Directed at C.D.C., Shooting Manifests Worst Fears
www.nytimes.com
Reposted by Rahul Ganatra
johnrossmd.bsky.social
Wild case of ChatGPT almost killing a guy by telling him to substitute sodium bromine for table salt (sodium chloride) #medsky www.acpjournals.org/doi/10.7326/...
With improvement, he was able to report that he had recently noticed new-onset facial acne and cherry angiomas, fatigue, insomnia, subtle ataxia, and polydipsia, further suggesting bromism. He also shared that, after reading about the negative effects that sodium chloride, or table salt, has on one's health, he was surprised that he could only find literature related to reducing sodium from one's diet. Inspired by his history of studying nutrition in college, he decided to conduct a personal experiment to eliminate chloride from his diet. For 3 months, he had replaced sodium chloride with sodium bromide obtained from the internet after consultation with ChatGPT, in which he had read that chloride can be swapped with bromide, though likely for other purposes, such as cleaning.
Gradually, over the course of a 3-week admission, his chloride and anion gap normalized and psychotic symptoms improved. He was tapered off risperidone before discharge and remained stable off medication at a check-in 2 weeks after discharge. His bromide level ultimately was 1700 mg/L (21 mmol/L; reference range, 0.9 to 7.3 mg/L).
rbganatra.bsky.social
I agree, it feels like we are living through a big shift in how people search for medical information.

I remember learning about using MeSH terms to search PubMed in medical school- how far we've come !
rbganatra.bsky.social
Fewer than 10% of published observational studies in this sample used DAGs to justify confounder selection.

This is a huge missed opportunity for both readers and researchers.

DAGs are invaluable in research design and critical appraisal.
rbganatra.bsky.social
“I can tell you personally, hot dogs are very slippery,” the fire chief said. “I did not know that.”
Reposted by Rahul Ganatra
samjakeengland.bsky.social
Why do treehoppers look so weird?! Our latest paper, out this week in @pnas.org, suggests a perhaps unexpected reason - static electricity ⚡ We show that treehoppers can detect the electrostatic cues of predators and that their crazy shapes may boost their electrosensitivity! doi.org/10.1073/pnas...
Electroreception in treehoppers: How extreme morphologies can increase electrical sensitivity | PNAS
The link between form and function of an organism’s morphology is usually apparent or intuitive. However, some clades of organisms show remarkable ...
doi.org
rbganatra.bsky.social
Im not sure why bluesky has me permanently tuned in to the Paul Williams show, but I'm here for it!
rbganatra.bsky.social
I mean, you have identified two of (im guessing) many important causes for the observation that many fewer people prescribe buprenorphine than could - very valuable!
rbganatra.bsky.social
Though I also wonder what else, besides prejudice and stigma, contributes to this "not my area" problem. Intimidation? Inertia? Suspicion of new drugs?
rbganatra.bsky.social
Great point Paul. I am reminded of physicians I worked with over the years who never really made it a priority to learn about HIV medications.