Joel Topf
@kidneyboy.bsky.social
7.4K followers 780 following 27K posts
Saying the product of the kidneys is urine is like saying the product of a factory is pollution. Urine is a by-product. The product is homeostasis. COI: https://pbfluids.com/about/
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kidneyboy.bsky.social
This second paragraph is so important. There has not been the same social media diaspora in India that we have seen in the US #MedTwitter
ericstrong.bsky.social
Specifically peak #MedTwitter felt like 2017-2018, whereas IMHO peak optimism at the attending level in the US for using social media in med ed peaked earlier than this. Maybe ~2016.

Globally, there are countries where I don’t know if social media use in med ed has even peaked yet.
Reposted by Joel Topf
hswapnil.medsky.social
ICYMI, recording now live
Excellent exposition on lower doses, anti coagulation and much more. Lot of RCTs in this space

youtu.be/xfEVlh_68vc?... by @nephcrit.bsky.social #NephGR #NephSky
kidneyboy.bsky.social
What was peak #MedTwitter?

What was the moment of greatest optimism for the idea of social media as a major driver of medial education?

I have my answer, but I'm going to keep my powder dry while I listen for your answers (but since this is BlueSky, I wonder if this will generate much heat)
kidneyboy.bsky.social
"When The Goopies politely made their way on set, each member was wearing a different color neckerchief like an indie new-wave version of Sailor Moon"

My daughter is bassist for The Goopies. My daughter is a Goopy!

www.michigandaily.com/arts/music/h...
Three local bands bring their diverse sounds to annual WCBN show
Over the course of three acts, Horse Bomb, Odd Reality and The Goopies took the audience on a roller coaster ride of a show.
www.michigandaily.com
Reposted by Joel Topf
weddellite.bsky.social
Megan Prochaska introduces the Fredric L Coe Symposium in war-ravaged Chicago
kidneyboy.bsky.social
For sure. Your point is a good one. And it was a sharp blog post
kidneyboy.bsky.social
Can’t stop staring at the prevalence of hypertension among young people.

www.ahajournals.org/doi/epub/10....
kidneyboy.bsky.social
that post from feb looks outdated, here is how opinion evidence answered your query.
kidneyboy.bsky.social
That feels like a feature that open evidence will add soon enough
Reposted by Joel Topf
lollardfish.bsky.social
- My talk is too long
- But maybe if I read it fast
- Lots of people have tried this
- It didn't work for those people
- But maybe ...
kidneyboy.bsky.social
Try open evidence.
www.openevidence.com

Then tell me, who the hell is paying $580 for UpToDate
Reposted by Joel Topf
wormbuxx.bsky.social
Now I’m falling asleep and she’s calling a cob
kidneyboy.bsky.social
Which fucker at the ABIM thought that the day that IM board scores came out was a good day to do scheduled maintenance?
Reposted by Joel Topf
nephjc.bsky.social
1/10
Welcome to #TenPostNephJC
Last #NephJC we discussed tolerance induction in HLA matched 🫘 transplants with donor Hematopoietic stem cells (MDR-101).
Missed the Chimeri-chat? No worries - We’re quite “tolerant” to those who missed their IS(Informative Session)!

pubmed.ncbi.nlm.nih.gov/39922283/
kidneyboy.bsky.social
From Richard Lafayette at GlomCon
kidneyboy.bsky.social
but mandating treatment with something that is not available as SoC is also a little crazy.

And "allowing" is an escape hatch from the ethical dilemma of enrolling a patient on sub state-of-the-art therapy for the length of the trial (thankfully, only a year at this time)
kidneyboy.bsky.social
And allow use of SGLT2i and sparsentan or atrasentan as long as they are started before study drug is initiated

No conventional steroids
No coated budesonide
kidneyboy.bsky.social
makes for an interesting question, why should countries where the drugs will not be available enroll patients in trials?

The control group I am seeing in new IgAN trials:
requiured ACEi or ARB at maximum tolerated doses but no titration period like in Fidelio/Figaro trials
Reposted by Joel Topf
hswapnil.medsky.social
Want to get your own version of #NephJC merch such as this pretty and useful backpack? 🎒

Donate to a good cause and get some swag too

www.nephjc.com/news/2025/9/...
NephJC branded backpack
kidneyboy.bsky.social
I think we are having a raging agreement. I'm all in favor of active controls. In fact at our research center we are refusing to consider any trials with drug against ACEi/ARB/Flozin. That ship has sailed.
kidneyboy.bsky.social
Dan Dickerson is legendary. He is no sacrifice.
kidneyboy.bsky.social
According to my sources FS1