Mike Johansen
@mikejohansenmd.medsky.social
Primary Care doc, likes research, teaches residents, #HSR, #MEPS, #FamilyMedicine
Pinned
Don't be a point-estimatologist.
Don't think you will beat the algorithms.
Don't do #quantifauxication.
Don't think you will beat the algorithms.
Don't do #quantifauxication.
Fascinating
the Ipsos Pride survey is genuinely an awesome product, but jesus the difference in the UK/US on trans issues is nuts
November 26, 2025 at 3:11 AM
Fascinating
Reposted by Mike Johansen
Reposted by Mike Johansen
I did not know it was this bad
Look at the mortality in younger females (versus males) in CKD 5
jamanetwork.com/journals/jam... in @jamainternalmed.com from Alberta
#NephSky #GenderDisparities
Look at the mortality in younger females (versus males) in CKD 5
jamanetwork.com/journals/jam... in @jamainternalmed.com from Alberta
#NephSky #GenderDisparities
November 25, 2025 at 7:14 PM
I did not know it was this bad
Look at the mortality in younger females (versus males) in CKD 5
jamanetwork.com/journals/jam... in @jamainternalmed.com from Alberta
#NephSky #GenderDisparities
Look at the mortality in younger females (versus males) in CKD 5
jamanetwork.com/journals/jam... in @jamainternalmed.com from Alberta
#NephSky #GenderDisparities
Reposted by Mike Johansen
New @pnas.org
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
Tattoo ink induces inflammation in the draining lymph node and alters the immune response to vaccination | PNAS
Despite safety concerns regarding the toxicity of tattoo ink, no studies have reported
the consequences of tattooing on the immune response. In thi...
www.pnas.org
November 25, 2025 at 7:35 PM
New @pnas.org
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
"This work represents the most extensive study to
date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing" including reduced response to Covid vaccination
www.pnas.org/doi/10.1073/...
Reposted by Mike Johansen
Third unvaccinated Kentucky baby dies of whooping cough.
Pertussis, best prevented with a vaccine, has killed three Kentucky babies in the last 12 months.
kentuckylantern.com/2025/11/25/t...
Pertussis, best prevented with a vaccine, has killed three Kentucky babies in the last 12 months.
kentuckylantern.com/2025/11/25/t...
Third unvaccinated Kentucky baby dies of whooping cough • Kentucky Lantern
A third unvaccinated infant in Kentucky has died of pertussis as public health officials urge Kentuckians to get vaccinated against the disease.
kentuckylantern.com
November 25, 2025 at 3:28 PM
Third unvaccinated Kentucky baby dies of whooping cough.
Pertussis, best prevented with a vaccine, has killed three Kentucky babies in the last 12 months.
kentuckylantern.com/2025/11/25/t...
Pertussis, best prevented with a vaccine, has killed three Kentucky babies in the last 12 months.
kentuckylantern.com/2025/11/25/t...
Reposted by Mike Johansen
#NephJCshort on BICAR-ICU2 #Medsky #Nephsky
✍️ By @nephroseeker.medsky.social
🎭 Bicarbonate makes the picture look cleaner: better pH, more time. But beneath the smoother numbers, the patient hasn't changed. It's the same story, just told in softer colors
www.nephjc.com/news/2025/10...
✍️ By @nephroseeker.medsky.social
🎭 Bicarbonate makes the picture look cleaner: better pH, more time. But beneath the smoother numbers, the patient hasn't changed. It's the same story, just told in softer colors
www.nephjc.com/news/2025/10...
Dialysis deferred, logic recycled: BICAR ICU2 — NephJC
NephJC short on BICAR-ICU2
www.nephjc.com
November 25, 2025 at 12:19 AM
#NephJCshort on BICAR-ICU2 #Medsky #Nephsky
✍️ By @nephroseeker.medsky.social
🎭 Bicarbonate makes the picture look cleaner: better pH, more time. But beneath the smoother numbers, the patient hasn't changed. It's the same story, just told in softer colors
www.nephjc.com/news/2025/10...
✍️ By @nephroseeker.medsky.social
🎭 Bicarbonate makes the picture look cleaner: better pH, more time. But beneath the smoother numbers, the patient hasn't changed. It's the same story, just told in softer colors
www.nephjc.com/news/2025/10...
Reposted by Mike Johansen
That’s basically what we do at VAI. They are so much smarter than us dinosaurs, why should they waste 40-70% of their time writing science fiction (grants)?
November 25, 2025 at 1:43 PM
That’s basically what we do at VAI. They are so much smarter than us dinosaurs, why should they waste 40-70% of their time writing science fiction (grants)?
As someone who works in an academic adjacent world, I spend little time in the halls of academic medicine. Every year, I go to our conference andvcatch-up with people I enjoy. Here are a few thoughts that I shouldn't say out loud, but I'm a small account on BS. What could go wrong?
1/
1/
November 25, 2025 at 1:28 PM
As someone who works in an academic adjacent world, I spend little time in the halls of academic medicine. Every year, I go to our conference andvcatch-up with people I enjoy. Here are a few thoughts that I shouldn't say out loud, but I'm a small account on BS. What could go wrong?
1/
1/
This ecosystem is really the way forward for much of CME and residency education. It has the right structure of not being too reliant on anyone individual, while offering reasonable diverse perspectives.
An announcement
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
www.nephjc.com/news/2025/11...
#NephJC
@kidneyboy.bsky.social and moi hand over the @nephjc.bsky.social reigns to @nephroseeker.medsky.social & @brianrifkin.bsky.social
Taking the reigns — NephJC
In April 2014, Swapnil and I launched NephJC—and within weeks we were overwhelmed by the sheer work of running a twice-monthly, Twitter-based journal club. Fortunately, we also had a deep bench of fri...
www.nephjc.com
November 25, 2025 at 12:59 PM
This ecosystem is really the way forward for much of CME and residency education. It has the right structure of not being too reliant on anyone individual, while offering reasonable diverse perspectives.
I don't really have any other way of saying it: umbrella systematic reviews are dumb.
November 25, 2025 at 12:56 PM
I don't really have any other way of saying it: umbrella systematic reviews are dumb.
Reposted by Mike Johansen
the European ICE (petrol + diesel) auto market is in a death spiral while EV sales boom...except TSLA. September saw some quarter-end window dressing but October was a return to the regularly scheduled declines of more than 40% YoY. Elon + diesel are dead letters in the EU auto market at this point.
November 25, 2025 at 12:17 PM
the European ICE (petrol + diesel) auto market is in a death spiral while EV sales boom...except TSLA. September saw some quarter-end window dressing but October was a return to the regularly scheduled declines of more than 40% YoY. Elon + diesel are dead letters in the EU auto market at this point.
Reposted by Mike Johansen
There's a really fantastic piece to be written on the way that social media makes some people believe they are in a customer service relationship with the people they are talking to online.
I want to make something very clear to everyone: I do not work for you. You don't sign my paychecks and the expectation that I do is frankly insane. Go away.
November 24, 2025 at 2:53 PM
There's a really fantastic piece to be written on the way that social media makes some people believe they are in a customer service relationship with the people they are talking to online.
Reposted by Mike Johansen
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
November 25, 2025 at 10:56 AM
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
Reposted by Mike Johansen
November 25, 2025 at 12:20 AM
You love the mandolorian until you absolutely hate it.
The Mandalorian movie hits next and oh god it’s going to be so bad, save that energy up
November 24, 2025 at 10:06 PM
You love the mandolorian until you absolutely hate it.
Love that fact that I renewed some of my accounting knowledge with googling enron fraud last week.
In the memo, “Nvidia also responds to claims that the ‘current situation is analogous to historical accounting frauds (Enron, WorldCom, Lucent) that featured vendor financing and SPVs [special purpose vehicles.)’”
@barrons.com $NVDA
@firstadopter.bsky.social
www.barrons.com/articles/nvi...
@barrons.com $NVDA
@firstadopter.bsky.social
www.barrons.com/articles/nvi...
November 24, 2025 at 7:35 PM
Love that fact that I renewed some of my accounting knowledge with googling enron fraud last week.
Reposted by Mike Johansen
Man, whatever's in those files, it must be pretty horrible
Really looks like the United States is about to launch a regime change war against Venezuela with:
-No casus belli
-No authorization from Congress
-No allies or international support
-No plan for a post-Maduro Venezuela
-No preparation for any sort of stabilization or containment of the fallout
-No casus belli
-No authorization from Congress
-No allies or international support
-No plan for a post-Maduro Venezuela
-No preparation for any sort of stabilization or containment of the fallout
November 24, 2025 at 6:25 PM
Man, whatever's in those files, it must be pretty horrible
Strong statement!
I've seen a lot of terrible nutrition studies, but this one could be the worst ever.
Hey, do another one! "Model" what happens when you eat kale instead of Doritos! Does your diet improve?
HT @marionnestle.bsky.social
Hey, do another one! "Model" what happens when you eat kale instead of Doritos! Does your diet improve?
HT @marionnestle.bsky.social
November 24, 2025 at 2:15 PM
Strong statement!
Summary of billions of $$'s worth of memory loss research:
mabs: maybe a little w/lots of side effects
donepezil: a little is generous
Non-memory loss research that impacts memory loss:
BP reduction: effects found!
Zoster vax: effects found!
mabs: maybe a little w/lots of side effects
donepezil: a little is generous
Non-memory loss research that impacts memory loss:
BP reduction: effects found!
Zoster vax: effects found!
November 24, 2025 at 1:11 PM
Summary of billions of $$'s worth of memory loss research:
mabs: maybe a little w/lots of side effects
donepezil: a little is generous
Non-memory loss research that impacts memory loss:
BP reduction: effects found!
Zoster vax: effects found!
mabs: maybe a little w/lots of side effects
donepezil: a little is generous
Non-memory loss research that impacts memory loss:
BP reduction: effects found!
Zoster vax: effects found!
IT CAN'T BE TRUE!!! GLP-1's were supposed to work on everything from tennis elbow to severe obesity to Alzheimers.
finance.yahoo.com/news/novo-no...
finance.yahoo.com/news/novo-no...
Novo Nordisk says Alzheimer's drug trial fails, hammering shares
COPENHAGEN () -Novo Nordisk said on Monday an older oral version of its semaglutide drug failed to meet its main goal in late-stage trials testing whether the medicine can slow cognitive decline in A...
finance.yahoo.com
November 24, 2025 at 12:58 PM
IT CAN'T BE TRUE!!! GLP-1's were supposed to work on everything from tennis elbow to severe obesity to Alzheimers.
finance.yahoo.com/news/novo-no...
finance.yahoo.com/news/novo-no...
This is really good. You'll see this in systems all over the place.
Are a small number of legacy disciplines dragging the whole of government down? A provocation:
medium.com/@jamestplunk...
Government seems increasingly unable to cope with the pace and complexity of today's world. Why? 1/n
medium.com/@jamestplunk...
Government seems increasingly unable to cope with the pace and complexity of today's world. Why? 1/n
The disciplines theory of government
Are legacy disciplines dragging the whole operation down?
medium.com
November 24, 2025 at 11:56 AM
This is really good. You'll see this in systems all over the place.
Reposted by Mike Johansen
Antifungal 'Nystatin' is named for the NY State Department of Health.
'Statins', on the other hand, are from Latin 'stare' meaning to "stay or hold still" for their ability to slow or stop cholesterol production via inhibition of liver enzyme HMG-CoA reductase.
'Statins', on the other hand, are from Latin 'stare' meaning to "stay or hold still" for their ability to slow or stop cholesterol production via inhibition of liver enzyme HMG-CoA reductase.
Chemist Rachel Fuller Brown was born #OTD in 1898. She co-discovered the antifungal nystatin while doing research for the New York State Department of Health, hence the name. (1/2) 🧪 👩🔬
Image: Smithsonian Institution
Image: Smithsonian Institution
November 23, 2025 at 6:32 PM
Antifungal 'Nystatin' is named for the NY State Department of Health.
'Statins', on the other hand, are from Latin 'stare' meaning to "stay or hold still" for their ability to slow or stop cholesterol production via inhibition of liver enzyme HMG-CoA reductase.
'Statins', on the other hand, are from Latin 'stare' meaning to "stay or hold still" for their ability to slow or stop cholesterol production via inhibition of liver enzyme HMG-CoA reductase.
What could possibly go wrong?
November 23, 2025 at 2:41 PM
What could possibly go wrong?
Reposted by Mike Johansen
the last 24 hours on X, summed up:
November 23, 2025 at 2:26 PM
the last 24 hours on X, summed up: