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Reposted by Romain Koszul

David Bikard @dbikard.bsky.social · 7h

Entretien pour Brut sur la vie Miroir, l'ingénierie génétique et l'éthique de ces recherches: www.brut.media/fr/videos/sc...

Manipulations génétiques, virus créés par l’IA, bactéries miroirs : quelles limites à la recherche scientifique ?

Elles pourraient aider à lutter contre les cancers… mais aussi détruire toute trace de vie sur Terre ! Ce sont les bactéries miroirs. En avez-vous déjà entendu parler ? Et la vie miroir, ça vous dit q...

www.brut.media

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Reposted by Romain Koszul

The Francis Crick Institute @crick.ac.uk · 2d

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

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Reposted by Romain Koszul

Stephan Gruber @gruberlab.bsky.social · 2d

How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...

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Reposted by Romain Koszul

Jean-Yves Tinevez @jytinevez.bsky.social · 4d

Job alert!

We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks?

See also on the forum:
forum.image.sc/t/research-e...

Research engineer in Bioimage Analysis for the researchers of the inIdEx FORMULA

Hi all We are looking for a bioimage analysis to work in an image analysis core facility in beautiful Paris. Can I ask you to share this opportunity with your networks? The position is in the Instit...

forum.image.sc

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Reposted by Romain Koszul

Tung Le @tunglejic.bsky.social · 8d

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

John Innes Centre @johninnescentre.bsky.social · 8d

Shortlisted candidates will be invited to give a seminar at the Fellows Conference, which will be held on 10 March 2026.

Candidates who win Fellowships will be offered a Tenure Track Group Leader position from the outset, initially for 5 years.

Find out more: www.jic.ac.uk/training-car...

Independent Research Fellowships Leading to Tenured Faculty Positions | John Innes Centre

The John Innes Centre (JIC), is a world leading centre of excellence in plant and microbial sciences based on the Norwich Research Park, UK. We are inviting applications from outstanding researchers…

www.jic.ac.uk

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Reposted by Romain Koszul

Géraldine Laloux @lalouxlab.bsky.social · 16d

📝New preprint! #MicroSky

🕰️We chart the full, synchronized lifecycle of a predatory bacterium using Hi-C, RNA-seq, ChIP-seq & microscopy.

🧬We uncover dramatic shifts in nucleoid architecture & transcription, tightly coordinated with predation.

www.biorxiv.org/content/10.1...

Dynamics and interplay of gene expression and chromosome organization across a predatory lifecycle

The obligate predatory bacterium Bdellovibrio bacteriovorus alternates between a motile attack phase and a growth phase inside another bacterium, during which it undergoes multiple rounds of DNA repli...

www.biorxiv.org

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Romain Koszul @rkoszul.bsky.social · 16d

Pour un licencié en droit on aurait pu espérer plus de discernement...

Reposted by Romain Koszul

Mehdi Hasan @mehdirhasan.bsky.social · 21d

What’s more astonishing: 1) that the president clearly believes, and repeatedly suggests, that asylum seekers are people from mental asylums, or 2) that no journalist has ever challenged him on this and no mainstream media outlets have done any deep dives on this story?

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Romain Koszul @rkoszul.bsky.social · 21d

ceci dit 40 avec les gros mollets c'est vraiment de plus en plus rare à Paris... par contre du motorisé débridé ou pas qui s'impatiente collé à ton siège enfant quand tu montes une côte avec un gamin...

Romain Koszul @rkoszul.bsky.social · 22d

New paper!
We generated and/or (re)analyzed ~100 #metagenomics Hi-C datasets to provide a comprehensive analysis of bacterial and viral metagenomes across VERY different environments.
Congratulations to all authors especially Amaury Bignaud and @mmarbout.bsky.social for the huge work!
#metaHiC

Martial Marbouty @mmarbout.bsky.social · 22d

You like phages ? In this publication, we use metaHiC and our new version of the MetaTOR pipeline to challenge the traditional view of phages with a narrow host range.
@rkoszul.bsky.social @natmicrobiol.nature.com @cnrs.fr @institutpasteur.bsky.social

www.nature.com/articles/s41...

Phages with a broad host range are common across ecosystems - Nature Microbiology

Proximity-ligation-based sequencing from 111 samples and 5 environments reveals that a substantial proportion of phages infect multiple species.

www.nature.com

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Reposted by Romain Koszul

Gilles FISCHER @gillesfischer.bsky.social · 25d

New preprint from the lab: we show that the ability to switch mating type was lost at least 13 times independently in the evolution of S. cerevisiae. At least 27% of isolates are heterothallic with a strong association with polyploidy and heterozygosity
www.biorxiv.org/content/10.1...

Repeated losses of self-fertility shaped heterozygosity and polyploidy in yeast evolution

Evolutionary transitions in mating strategy have profound consequences for genetic variation and adaptation. In Saccharomyces cerevisiae, mating-type switching is a central feature of the life cycle t...

www.biorxiv.org

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Reposted by Romain Koszul

Harmit Singh Malik @harmitmalik.bsky.social · 24d

www.cell.com/cell/abstrac...

A host organelle (in sea slugs) integrates stolen chloroplasts for animal photosynthesis

A host organelle integrates stolen chloroplasts for animal photosynthesis

Sea slugs steal foreign chloroplasts and store them in specialized organelles that facilitate photosynthesis and eventual digestion to mediate starvation resistance.

www.cell.com

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Romain Koszul @rkoszul.bsky.social · 24d

aucun pb aux USA pour ce genre de discours, c'est bien la différence majeure avec l'Europe que Vance essaie de supprimer en menaçant à tout va.

Reposted by Romain Koszul

Tobias Warnecke @tobiaswarnecke.bsky.social · Sep 8

Please re-post:

Interested in chromatin and its evolution? Good news! There's still time to join us in beautiful Catalonia (9-12 Dec) to discuss eukaryotic, bacterial, archaeal, and viral chromatin and how it all hangs together meetings.embo.org/event/24-evo...

Abstract deadline: 30 September

EvoChromo: Evolutionary approaches to research in chromatin

Chromatin is the complex of DNA, RNA and protein that is found making up the chromosomes in eukaryotic cells. Chromatin is essential for proper genome function and is involved in chromosome segregati…

meetings.embo.org

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Reposted by Romain Koszul

Institut Pasteur | 130 years of biomedical research @pasteur.fr · Sep 1

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry.

Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, [email protected], PPU-EID @upcite.bsky.social & more 🧬

Register now ✍️ www.pasteur.fr/en/education...

Pasteur-Paris University International Doctoral Programme, The call for enrollment of students in October 2026 will be open from September 1st to October 20th, 2025

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Reposted by Romain Koszul

Eduardo Rocha @epcrocha.bsky.social · Sep 8

Willing to join us @pasteur.fr for a PhD for a project on how interactions between mobile genetic elements shape bacterial adaptation? Subject to be tailored to candidates with keen interest in evolution, genomics, computational biology, microbiology. Check www.pasteur.fr/en/education...

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Reposted by Romain Koszul

The Cecere Laboratory @cecerelab.bsky.social · Sep 7

🍽️🧬 How do diet and gut microbes shape fertility across generations? 🪱🔬 Our Laboratory at #InstitutPasteur is recruiting a PhD student to study epigenetic inheritance of fertility using C. elegans. Fully funded via the International PPU program. Apply now! 🌍 #PhDposition #Epigenetics #Inheritance

Institut Pasteur | 130 years of biomedical research @pasteur.fr · Sep 1

🎓 Applications for Institut Pasteur's PhD programs open Sept 1-Oct 20, 2025 for October 2026 entry.

Apply to up to 4 projects across 6 programs: PPU, PPU-IMAGINE @institutimagine.bsky.social, [email protected], PPU-EID @upcite.bsky.social & more 🧬

Register now ✍️ www.pasteur.fr/en/education...

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Reposted by Romain Koszul

Zeynep Baharoglu @zeynepbaharoglu.bsky.social · Sep 6

So excited our antibiotic potentiation story is out 🤩 Led by the extraordinary @manonlang.bsky.social with @fox-science.bsky.social & @amazeld.bsky.social +amazing collaborators @immunobladder.bsky.social @imaneelmeouche.bsky.social 🦠 We believe it can make a difference in #AMR infections!

Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters

Uridine boosts aminoglycoside treatment efficiency against antibiotic-susceptible as well as antibiotic-resistant E. coli strains.

www.science.org

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Romain Koszul @rkoszul.bsky.social · Sep 5

C'était la zone dès la moyenne section de maternelle si je me souviens bien...

Romain Koszul @rkoszul.bsky.social · Sep 1

Le gars semble a 2 doigts de découvrir le doctorat.

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Reposted by Romain Koszul

Jolan C. Bertrand @thejolan.bsky.social · Aug 28

(Suite) en tapant votre nom dans la barre de recherche de cette database : www.theatlantic.com/technology/a... (hésitez pas à checker plusieurs versions de votre nom, à intervertir nom et prénom etc.) pour voir si une ou plusieurs de vos oeuvres y sont.
Et si vous êtes effectivement concerné-es (2/)

Search LibGen, the Pirated-Books Database That Meta Used to Train AI

Millions of books and scientific papers are captured in the collection’s current iteration.

www.theatlantic.com

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Romain Koszul @rkoszul.bsky.social · Aug 25

C'est exactement ça.
Idem pour sa base qui a même pas l'excuse d'avoir gardé un schéma mental d'etudiant UNEF bloqué en 1971...

Romain Koszul @rkoszul.bsky.social · Aug 21

But still better I think than being cited but only to state you did not find what you find, and use that false claim to support your results as new (and eventually push them into Nature)

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Reposted by Romain Koszul

Elphege Nora Lab at UCSF @elphegenoralab.bsky.social · Aug 16

New preprint with @gfudenberg.bsky.social

We find the rate of cohesin loop extrusion in cells is set by NIPBL dosage and tunes many aspects of chromosome folding.

This provides a molecular basis for NIPBL haploinsufficiency in humans. 🧵👇

www.biorxiv.org/content/10.1...

NIPBL dosage shapes genome folding by tuning the rate of cohesin loop extrusion

Cohesin loop extrusion is a major driver of chromosome folding, but how its dynamics are controlled to shape the genome remains elusive. Here we disentangle the contributions of the cohesin cofactors ...

www.biorxiv.org

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Romain Koszul @rkoszul.bsky.social · Aug 11

Last PhD work of @nathaliebastie.bsky.social and last postdoc work of @christophechapard.bsky.social, who are heading toward new projects. Kudos Axel Cournac for analysis and Laura Chaptal for cool inputs during revisions!

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