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Reposted by Rory Hennell James

Cascales Lab @cascaleslab.bsky.social · 2d

Open position to work on Type IX secretion (#T9SS) in our lab, in collaboration withe the group of Eric Reynolds at the Dental School of the University of Melbourne. Please spread the word, and forward to anyone potentially interested ! Apply here:
emploi.cnrs.fr/Offres/Docto...

Portail Emploi CNRS - Offre d'emploi - Thèse en Microbiologie-Biochimie (H/F)

emploi.cnrs.fr

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Reposted by Rory Hennell James

Pilhofer Lab 🦠❄️🔬 @pilhoferlab.bsky.social · 2d

🧐Checkout our preprint revealing the stepwise firing💥 mechanism of a Contractile Injection System @xujwet.bsky.social [email protected] trapped the complex by structure-guided engineering🧪 in multiple intermediate states and imaged them by multimodal #cryoEM❄️🔬
www.biorxiv.org/content/10.1...

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Reposted by Rory Hennell James

BeijingPalmer @beijingpalmer.bsky.social · 6d

Explaining to my wife that I cannot simply “read the books I’ve already bought and haven’t read” like some kind of peasant.

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Reposted by Rory Hennell James

Tobias Warnecke @tobiaswarnecke.bsky.social · 12d

Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism

my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

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Reposted by Rory Hennell James

Biozentrum, University of Basel @biozentrum.unibas.ch · 12d

Assistant/Associate Professor in Structural Biology, Biophysics or Biological Imaging

www.biozentrum.unibas.ch/open-positio...

#biozentrum #University #Basel #Professor #Structural #Biology #Biophysics #Biological #Imaging

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Reposted by Rory Hennell James

Adam Rutherford @adamrutherford.bsky.social · 17d

Phenomenal. In my 10 year update of A Brief History, I make the point that in the first edition, not one disease had been successfully treated using gene therapy. Today that number is at least 7.

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Reposted by Rory Hennell James

Wilbert Bitter @wilbertbitter.bsky.social · 18d

PPE51 is one of the best candidates to form a MOM transport channel. However, our data indicate that it is not that simple. PPE51 mutations in Mmarinum (4 close homologs) indeed reduce the growth on glycerol & glucose, but also highly increase permeability.. and no, we do not fully understand this

PPE51 modulates membrane integrity in Mycobacterium marinum | mBio

The impermeable outer membrane of pathogenic mycobacteria presents a major obstacle to nutrient acquisition and antibiotic penetration. PPE51, a substrate of the ESX-5 secretion system, has previously...

journals.asm.org

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Reposted by Rory Hennell James

bioRxiv Biochemistry @biorxiv-biochem.bsky.social · 22d

Structure and substrate recognition by the Twin-arginine translocation (Tat) pathway core complex https://www.biorxiv.org/content/10.1101/2025.09.18.677151v1

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Reposted by Rory Hennell James

Moose Allain @mooseallain.bsky.social · 22d

An Infusiast

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Rory Hennell James @rorydhj.bsky.social · 23d

I've recently switched to Sumatra PDF for this reason, but I haven't found a decent free reader for android on my phone/tablet

Reposted by Rory Hennell James

Samuel King @samuelhking.bsky.social · 24d

Many of the most complex and useful functions in biology emerge at the scale of whole genomes.

Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵

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Rory Hennell James @rorydhj.bsky.social · 29d

Is anyone in #MicroSky aware of the rapamycin dimerisation working in (myco)bacteria? Or some other inducible dimerisation?

I'd like to give this a go but I'm wary of fusing a 24-mer to my protein of interest

Benoît Zuber @benoitzuber.bsky.social · Sep 11

Paper alert🚨
Label your protein of interest and localize it in cryoET 👁️❄️

Genetically encoded FerriTag as a specific label for cryo-electron tomography: Structure www.cell.com/structure/fu...

Genetically encoded FerriTag as a specific label for cryo-electron tomography

Wang et al. present an optimized labeling strategy for cryo-electron tomography based on genetically encoded FerriTag. This system uses rapamycin to recruit iron-loaded ferritin to target proteins, en...

www.cell.com

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Rory Hennell James @rorydhj.bsky.social · Sep 7

Printing files from Nemo Andrea here:https://www.printables.com/model/310139-transmission-electron-microscope

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Rory Hennell James @rorydhj.bsky.social · Sep 7

Pretty pleased with my 3d-printed Jeol 1400. But does anyone in #TeamTomo or #cryoEM have a 3D model or technical drawings of a Krios/Aquilos/Arctis I could have a go at printing?

A 3D printed model of a Jeol 1400 transmission electron microscope. The microscope is a column of white plastic on a black base with black and gold accents.

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Rory Hennell James @rorydhj.bsky.social · Sep 4

But have you tried a Franzbrötchen?

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Rory Hennell James @rorydhj.bsky.social · Aug 31

This looks super cool, and could be the solution to a problem I've been having for a while.

Congrats all!

Tanmay Bharat @tbharat-lab.bsky.social · Aug 31

Sub-cellular chemical mapping in bacteria using correlated cryogenic electron and mass spectrometry imaging

Congrats Hannah Ochner and authors on this important paper! Strong collaboration with @kiranrpatil.bsky.social

www.biorxiv.org/cgi/content/...
@mrclmb.bsky.social @wellcometrust.bsky.social

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Rory Hennell James @rorydhj.bsky.social · Aug 31

Mostly 30/31 😂

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Rory Hennell James @rorydhj.bsky.social · Aug 30

I just got back from a wedding where this was a major topic of conversation. One friend put his back out turning to listen to the speeches.

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Rory Hennell James @rorydhj.bsky.social · Aug 28

I knew a kiwi student who saw "made with real fruit juice" on the label and thought it would be perfect for screwdrivers.

Apparently it still went down better than Stella at the graduate LGBTQ+ mixer

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Reposted by Rory Hennell James

Hannah Shelley, MLIS (Metadata, Lattes & Impostor Syndrome) @hannahshelley.bsky.social · Aug 13

Since search is dead, how soon do you think Google Scholar is headed for the Google Graveyard? I'm betting it's soon, and academia is NOT prepared

Google Scholar Is Doomed

Academia built entire careers on a free Google service with zero guarantees. What could go wrong?

hannahshelley.neocities.org

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Rory Hennell James @rorydhj.bsky.social · Aug 18

This was a brilliant course last year; I highly recommend it to anyone looking to improve their CryoFIB and CryoET skills!

Max Planck Institute of Biophysics @mpibp.bsky.social · Aug 18

We’re hosting the @embo.org Practical Course on In-situ structural biology by CryoFIB and CryoET in April 2026! 🧬❄️ You can expect hands-on training, cutting-edge methods, and a chance to work alongside leading experts in structural biology. 🔗 Apply by Dec 8, 2025: meetings.embo.org/event/26-in-...

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Reposted by Rory Hennell James

Chris Greening @greening.bsky.social · Aug 8

1/3 Electricity from air! In the top journal Nano Energy today, we report the first fuel cell that makes power from air alone. We achieved this by using the enzyme Huc to oxidize ambient hydrogen. This results in a continuous low-level power from air and higher outputs with industrial waste gases.

Nanoengineered bioanode with oxygen-insensitive hydrogenase for sustainable energy harvesting from atmospheric hydrogen and waste gases

Enzymatic biofuel cells (EBFCs) utilizing hydrogenases to oxidize hydrogen offer a sustainable approach to energy conservation. However, the oxygen se…

www.sciencedirect.com

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Rory Hennell James @rorydhj.bsky.social · Aug 7

Congratulations @emfurlong.bsky.social !

Science & Medicine at ANU @scienceanu.bsky.social · Aug 7

Three remarkable early-career researchers from ANU, Dr Emily Furlong, Dr Ashley Jones and Associate Professor Xiaolin Wang, have been recognised with prestigious ACT Young Tall Poppy Science Awards for their significant contributions to science. Congratulations!
science.anu.edu.au/news-events/...

Young science scholars flourish as tall poppies

Three early-career ANU academics have been honoured with ACT Young Tall Poppy Science Awards.

science.anu.edu.au

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Rory Hennell James @rorydhj.bsky.social · Aug 4

That means it's 10 years since I did my summer project at @diamondlightsource.bsky.social. How time flies!

Martin Walsh @walshdls.bsky.social · Aug 4

krios 1 @diamondlightsource.bsky.social celebrated 10 years of user operations last week - many people thought we were mad to plonk it down in this spot in the synchrotron …but its still there as we ended up with a lot more in a very small space of time !

Titan krios I (a 300 KeV Cryo transmission electron microscope) with its 10 yr birthday hat in the experimental hall of Diamond Light Source.

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Reposted by Rory Hennell James

Debnath Ghosal @debnathghosal.bsky.social · Aug 2

📣 New paper alert! Just out in Cell Reports! pubmed.ncbi.nlm.nih.gov/40644298/
Thrilled to share that we have discovered a brand-new anti-phage defense system! Bacteria have evolved various defense strategies (CRISPR etc) to counter phage attacks. We found a new one - fascinating and dramatic
⚔️🦠❄️🔬

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