Danny Saban
@sabanlab.bsky.social
Professor Immunologist leveraging the eye as an organ model system to study #neuroimmunology #mucosalimmunology #immuneprivilege #macrophages #microglia #DC #neutrophils https://youtube.com/@danielrsaban?si=4cOtXhcsvyKDGuMe
Pinned
Danny Saban
@sabanlab.bsky.social
· Aug 5
Check out our new preprint on a novel neuro-immune niche that underpins touch in the cornea
Reposted by Danny Saban
Not to be missed! Our next #globalimmuno talk, today Wednesday, November 5th at 9am PST, noon EST, 5pm GMT by Dr. Daniel Saban.
Title: “A Neuroimmune Niche that Underpins Touch Sensation”
ZOOM LINK: us06web.zoom.us/webinar/regi...
LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...
Title: “A Neuroimmune Niche that Underpins Touch Sensation”
ZOOM LINK: us06web.zoom.us/webinar/regi...
LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...
Welcome! You are invited to join a webinar: GLOBAL IMMUNOTALKS: Virtual immunology seminar series . After registering, you will receive a confirmation email about joining the webinar.
Subscribe to our YouTube channel to stay updated and participate in the discussions: https://www.youtube.com/c/GLOBALIMMUNOTALKS
We now offer:
✅ Live streaming on YouTube (in addition to Zoom)
✅ Asyn...
us06web.zoom.us
November 5, 2025 at 7:29 AM
Not to be missed! Our next #globalimmuno talk, today Wednesday, November 5th at 9am PST, noon EST, 5pm GMT by Dr. Daniel Saban.
Title: “A Neuroimmune Niche that Underpins Touch Sensation”
ZOOM LINK: us06web.zoom.us/webinar/regi...
LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...
Title: “A Neuroimmune Niche that Underpins Touch Sensation”
ZOOM LINK: us06web.zoom.us/webinar/regi...
LIVE ON YOUTUBE: www.youtube.com/@GLOBALIMMUN...
Welcome!
Dear Friends and Colleagues, we are finally on Bluesky!
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
Our lab uses human stem cell models to understand brain, spinal cord and peripheral nerve diseases, focusing on RNA metabolism and cellular autonomy.
We are based at NUS in Singapore at the Life Sciences Institute: www.nus.edu.sg/lsi/
www.nus.edu.sg
September 29, 2025 at 1:20 PM
Welcome!
#CSNeuroimmune25 Come learn about a novel neuro immune niche that underpins touch! Littleton Tues P2.38 13:00-14:30 youtu.be/BAtzNKj4wxA?si…
Supplemental Video 2_Littleton et al_2025
YouTube video by Daniel R. Saban
https://youtu.be/BAtzNKj4wxA?si…
September 7, 2025 at 7:43 PM
#CSNeuroimmune25 Come learn about a novel neuro immune niche that underpins touch! Littleton Tues P2.38 13:00-14:30 youtu.be/BAtzNKj4wxA?si…
Reposted by Danny Saban
Getting ready for #CSNeuroimmune25 tomorrow in NYC! Excited to see everyone, and looking forward to some cool #neuroimmunology! @cp-neuron.bsky.social @cp-immunity.bsky.social www.cell-symposia.com/neuroimmunol...
September 6, 2025 at 11:40 PM
Getting ready for #CSNeuroimmune25 tomorrow in NYC! Excited to see everyone, and looking forward to some cool #neuroimmunology! @cp-neuron.bsky.social @cp-immunity.bsky.social www.cell-symposia.com/neuroimmunol...
Reposted by Danny Saban
Reposted by Danny Saban
Some say you either have "it" or you don't, and that creativity cannot be learned, but that really misses the point. Creativity is lost in the wrong environment. We need to recognize the "night science" aspect of our work and that we need to nurture it in our training. www.nature.com/articles/d41...
Can creativity in science be learnt? These researchers think so
Time pressure gets in the way of ideas. Developing ‘creative oases’ and small grants for risky ideas can encourage innovative thinking in science.
www.nature.com
August 14, 2025 at 3:51 AM
Some say you either have "it" or you don't, and that creativity cannot be learned, but that really misses the point. Creativity is lost in the wrong environment. We need to recognize the "night science" aspect of our work and that we need to nurture it in our training. www.nature.com/articles/d41...
Check out our new preprint on a novel neuro-immune niche that underpins touch in the cornea
August 5, 2025 at 1:53 AM
Check out our new preprint on a novel neuro-immune niche that underpins touch in the cornea
Reposted by Danny Saban
Beautiful spatial transcriptomics of developing meninges and meningiomas. Hints into the origins of meningiomas arising from the dural border 🤩🧐
Cell atlas of the developing human meninges reveals a dura origin of meningioma
The vertebrate central nervous system is enveloped by the meninges, consisting of the pia, arachnoid, and dura layers. The arachnoid is hypothesised to give rise to the most common primary intracrania...
www.biorxiv.org
July 31, 2025 at 4:20 AM
Beautiful spatial transcriptomics of developing meninges and meningiomas. Hints into the origins of meningiomas arising from the dural border 🤩🧐
Reposted by Danny Saban
You don’t see #VisionResearch. But it sees you. Most of us don’t think about vision research. But millions live every day with the impact of it—when it’s there, and when
it’s not. Vision research changes lives. bit.ly/3GXVIaZ
#SeeWhatMatters #FundFederalVisionResearch
it’s not. Vision research changes lives. bit.ly/3GXVIaZ
#SeeWhatMatters #FundFederalVisionResearch
July 23, 2025 at 2:59 PM
You don’t see #VisionResearch. But it sees you. Most of us don’t think about vision research. But millions live every day with the impact of it—when it’s there, and when
it’s not. Vision research changes lives. bit.ly/3GXVIaZ
#SeeWhatMatters #FundFederalVisionResearch
it’s not. Vision research changes lives. bit.ly/3GXVIaZ
#SeeWhatMatters #FundFederalVisionResearch
Reposted by Danny Saban
Previously unknown prenatally derived macrophage is uniquely involved in lipid metabolism and vascular maintenance and is decreased and dysfunctional in age-related macular degeneration @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
April 22, 2025 at 3:17 PM
Previously unknown prenatally derived macrophage is uniquely involved in lipid metabolism and vascular maintenance and is decreased and dysfunctional in age-related macular degeneration @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
Reposted by Danny Saban
Fortmann, Grant et al. show that prenatally derived #macrophages support choroidal health and decline in age-related #maculardegeneration rupress.org/jem/article/...
📘 In our Clinical #Immunology Collection: rupress.org/jem/collecti...
#FOCIS2025
📘 In our Clinical #Immunology Collection: rupress.org/jem/collecti...
#FOCIS2025
June 20, 2025 at 3:15 PM
Fortmann, Grant et al. show that prenatally derived #macrophages support choroidal health and decline in age-related #maculardegeneration rupress.org/jem/article/...
📘 In our Clinical #Immunology Collection: rupress.org/jem/collecti...
#FOCIS2025
📘 In our Clinical #Immunology Collection: rupress.org/jem/collecti...
#FOCIS2025
Reposted by Danny Saban
Wow.. this cover!! 😍 @jem.org looking jazzy this month! Take a look at the July issue here 👉 rupress.org/jem/issue/22...
Our July issue is here! rupress.org/jem/issue/22...
The cover image depicts the spatial organization and cellular composition of the human choroid (posterior face) by multiplex immunofluorescence. From Fortmann et al. (doi.org/10.1084/jem....)
The cover image depicts the spatial organization and cellular composition of the human choroid (posterior face) by multiplex immunofluorescence. From Fortmann et al. (doi.org/10.1084/jem....)
July 8, 2025 at 12:28 PM
Wow.. this cover!! 😍 @jem.org looking jazzy this month! Take a look at the July issue here 👉 rupress.org/jem/issue/22...
Reposted by Danny Saban
Excited to share our new work, led by an exceptional graduate student, Tornike Mamuladze, on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || www.cell.com/cell/fulltex...
Mast cells regulate the brain-dura interface and CSF dynamics
Dural mast cells control cerebrospinal fluid dynamics at critical brain-dura interfaces,
specifically arachnoid cuff exit points. Their activation limits pathogen brain entry
via histamine-induced vas...
www.cell.com
July 24, 2025 at 8:10 PM
Excited to share our new work, led by an exceptional graduate student, Tornike Mamuladze, on the role of meningeal mast cells in regulation of brain/dura access points, with implications to CSF flow dynamics and meningitis || www.cell.com/cell/fulltex...
Reposted by Danny Saban
If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.
May 19, 2025 at 7:36 PM
If a foreign adversary snuck into our Federal budget and cut science research and education the way we’re cutting it ourselves — strategically undermining America’s long-term health, wealth, and security — we would likely consider it an act of war.
Organoids don’t have immune systems
ICYMI: #NIH announces a new initiative to reduce animal use in research by launching ORIVA, a new office dedicated to advancing non-animal methods. Read more in the Washington Update:
NIH Announces Initiative to Reduce Animal Research in Biomedical Portfolio
NIH announces an initiative to reduce the use of animals in NIH-funded research.
hubs.ly
May 18, 2025 at 3:10 PM
Organoids don’t have immune systems
Reposted by Danny Saban
Excited to see this collection out! Thank you to all the authors and reviewers who contributed!
May issue is online! Explore reviews on the #neuroimmune axis! The beautiful cover was designed by Ella Marushchenko, working with @jonykipnis.bsky.social. A brain encased in a walnut shell that is cracking open symbolizes our growing understanding of #neuroimmunology www.cell.com/immunity/iss...
May 13, 2025 at 5:29 PM
Excited to see this collection out! Thank you to all the authors and reviewers who contributed!
Assistant prof opening for Immunology umc.edu/som/Departme...
Employment Opportunities
The Department of Cell and Molecular Biology at the University of Mississippi Medical Center invites applications for a tenure-track faculty position at the rank of Assistant Professor. We seek an i...
umc.edu
May 7, 2025 at 3:44 PM
Assistant prof opening for Immunology umc.edu/som/Departme...
Reposted by Danny Saban
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now [email protected] #macrophages
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling
The local immunoregulatory mechanisms that safeguard the host from excessive lung
infection inflammation remain unclear. Yeung, Yokota et al. uncover the essential
role of nerve- and airway-associated...
www.cell.com
April 25, 2025 at 7:18 PM
Nerve- and airway-associated interstitial macrophages mitigate SARS-CoV-2 pathogenesis via type I interferon signaling: Immunity www.cell.com/immunity/ful... our study out now [email protected] #macrophages
Reposted by Danny Saban
Sejiro Littleton takes home the coveted #GliaCamp best talk award 🥇. “Neuroimmune niche underpins touch.” He’s on the market for a postdoc position, for those who are asking! @MosemanLab @FilianoLab and students organized another wonderful camp ⛺️. @LongJun_Wu killer keynote@ - who can ask for more
April 10, 2025 at 12:07 AM
Sejiro Littleton takes home the coveted #GliaCamp best talk award 🥇. “Neuroimmune niche underpins touch.” He’s on the market for a postdoc position, for those who are asking! @MosemanLab @FilianoLab and students organized another wonderful camp ⛺️. @LongJun_Wu killer keynote@ - who can ask for more
Reposted by Danny Saban
More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.
April 3, 2025 at 9:29 AM
More great content from @preprintclub.bsky.social @epelmanlab.bsky.social. This @biorxiv-immuno.bsky.social preprint from Liu et al. reports that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure.
Thank you @natrevimmunol.bsky.social and
Preprint Club, University of Toronto,
Alex Lac & Slava Epelman for reviewing our preprint!
www.nature.com/articles/s41...
Preprint Club, University of Toronto,
Alex Lac & Slava Epelman for reviewing our preprint!
www.nature.com/articles/s41...
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis - Nature Reviews Immunology
A preprint by Liu et al. shows that resident tissue macrophages in the conventional outflow tract regulate intraocular pressure in the steady state.
www.nature.com
April 1, 2025 at 2:28 AM
Thank you @natrevimmunol.bsky.social and
Preprint Club, University of Toronto,
Alex Lac & Slava Epelman for reviewing our preprint!
www.nature.com/articles/s41...
Preprint Club, University of Toronto,
Alex Lac & Slava Epelman for reviewing our preprint!
www.nature.com/articles/s41...
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Res…
March 14, 2025 at 12:51 AM
National Institutes of Health grants generated almost $95 billion in economic activity nationwide in FY 2024 according to a new report by United for Medical Res…
Reposted by Danny Saban
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...
Comparison of Research Spending on New Drug Approvals by the NIH vs the Pharmaceutical Industry
This cross-sectional study examines National Institutes of Health and pharmaceutical industry investments in recent drug approvals.
jamanetwork.com
March 10, 2025 at 2:15 PM
99% of new medicines developed by the pharmaceutical industry depend on NIH research jamanetwork.com/journals/jam...