Karen Schindler
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schindlerlab.bsky.social
Karen Schindler
@schindlerlab.bsky.social
1.3K followers 330 following 18 posts
Reproductive biologist studying how eggs are made
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Reposted by Karen Schindler
lacefieldlab.bsky.social
Check out our new manuscript on biorxiv on the role of MOS in mammalian oocyte meiosis: www.biorxiv.org/cgi/content/...
With @schindlerlab.bsky.social @giselacairobaza.bsky.social @muhammad-haseeb.bsky.social
A persistent intracellular bridge and cell cycle misregulation enable polar body cell divisions and tumor formation in Mos-deficient eggs
Mammalian female meiosis is uniquely regulated to produce a developmentally competent egg capable of supporting embryogenesis. During meiosis I, homologous chromosomes segregate, with half extruded in...
www.biorxiv.org
August 29, 2025 at 5:34 PM
Reposted by Karen Schindler
lacefieldlab.bsky.social
My department at Dartmouth Medical School is hiring a tenure-track Assistant Professor. We are looking broadly for a biochemist or cell biologist. Please share this add! apply.interfolio.com/171438
@dartmouthbcb.bsky.social @futurepislack.bsky.social
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio
apply.interfolio.com
August 27, 2025 at 8:50 PM
Reposted by Karen Schindler
jenelandino.bsky.social
Dartmouth is hiring! Come be my colleague. Biochemistry and Cell Biology is accepting applications for a tenure-track Assistant Professor position. Join us in New Hampshire for great science, nice people, and beautiful scenery ⛰️ apply.interfolio.com/171438
August 27, 2025 at 7:55 PM
Reposted by Karen Schindler
gzaffagnini.bsky.social
Happy Sunday everyone! Have a look at the latest #papers on #oocyte and #embryo cell biology! This week we have a collection of useful #protocols to monitor chromatin and transcription in our favourite cells!

biomed.news/bims-cebooc/...

Thanks @biomednews.bsky.social for preselecting!
#cebooc
June 1, 2025 at 7:57 AM
Reposted by Karen Schindler
ssrwinrs.bsky.social
Attention SSR Annual Meeting attendees:
Don't miss registration for the Lunch and Learn session with Dr. Kelly Diggs to sharpen up your mentoring skills!
#reprorocks #womeninstem
May 29, 2025 at 8:37 PM
schindlerlab.bsky.social
At FIR we love eggs and fertilization- worm or mouse!
May 23, 2025 at 9:02 PM
schindlerlab.bsky.social
Busy FIR days at the @mblscience.bsky.social. At the end of last week FIRbees learned how to collect and inject follicles and oocytes and experienced the beautiful diversity of marine reproductive biology strategies.
May 20, 2025 at 7:01 PM
schindlerlab.bsky.social
Last night the FIRbees at the @mblscience.bsky.social did a hands on activity to learn about how the Retinoic Acid wave controls spermatogenesis and how that impacts tubule staging. Such a cool and powerful activity from Beth Snyder- @rnaisthenewdna.bsky.social!
May 15, 2025 at 3:02 PM
schindlerlab.bsky.social
Section 2 of Frontiers in Reproduction @mblscience.bsky.social has started! FIRbees learned how to prep single cell suspensions from testes with Brian Hermann and sperm capacitation with @marianobuffone.bsky.social. Thanks to @10xGenomics and @Hamilton Thorne for tech support!
May 12, 2025 at 8:19 PM
schindlerlab.bsky.social
I'm up at the MBL to kick off Section 2 of Frontiers in Reproduction tonight. Missing Mother's Day with my kiddos, but my amazing husband did interviews with them to send me. This one had me in tears. He gets what we do and he's only 11.
May 11, 2025 at 2:50 PM
schindlerlab.bsky.social
Finally some positive news for the lab this week. Non-competitive renewal NoA arrived (phew) and a paper accepted (yay!)
April 16, 2025 at 2:31 PM
Reposted by Karen Schindler
jovinelab.org
New step taken towards non-hormonal contraception

news.ki.se/new-step-tak...
New step taken towards non-hormonal contraception
A new study from Karolinska Institutet shows how a small antibody fragment can block fertilisation by targeting a key protein on the surface of the egg. This discovery brings a non-hormonal contracept...
news.ki.se
April 14, 2025 at 7:42 AM
Reposted by Karen Schindler
thejainlab.bsky.social
For my first science post here, I’m proud to advertise our latest work exploring why germ cell connectivity is really important for meiosis 🐁

Done with some awesome colleagues @florpratto.bsky.social

www.nature.com/articles/s41...
Intercellular bridges are essential for transposon repression and meiosis in the male germline - Nature Communications
A conserved feature of metazoan meiosis is that it occurs in a syncytium. Here, the authors show that intercellular bridges that connect germ cells in a syncytium are critical for ensuring proper meio...
www.nature.com
April 8, 2025 at 10:47 PM
Reposted by Karen Schindler
barrlab.bsky.social
Thanks Senator @kim.senate.gov for the science round table at Rutgers. We discussed the importance of NIH funding for R&D, workforce training, & helping patients. Politicizing the NIH threatens our global competitiveness and quest for disease cures.

@schindlerlab.bsky.social
@matiset.bsky.social
Photo of Rutgers faculty Karen Schindler, Tara Matise, Matt Buckley and Maureen Barr with NJ Senator Andy Kim in a conference room
March 20, 2025 at 11:43 PM
Reposted by Karen Schindler
barrlab.bsky.social
I did something exciting today with my two amazing genetics dept colleagues @schindlerlab.bsky.social and @matiset.bsky.social. We joined a round table discussion on science, innovation and industry with NJ Senator Andy Kim @kim.senate.gov. We have some new strategies to #standupforscience2025! 💪🧪
March 19, 2025 at 8:22 PM
Reposted by Karen Schindler
matiset.bsky.social
Great pro-science rally today in Trenton at #standupforscience2025.
March 7, 2025 at 10:33 PM
Reposted by Karen Schindler
samwang.bsky.social
Close to 600 people for the Trenton Stand Up For Science rally. Great chants, NJ schools out in force, and scientists discovering their inner extrovert. Rush Holt led off, me at end.
March 7, 2025 at 9:10 PM
Reposted by Karen Schindler
barrlab.bsky.social
Scene from Rutgers "Hands Off Our Research" Protest. Professor Monica Driscoll - National Academy of Sciences member - rallies our undergrads, grad students, postdocs, staff, faculty, and community. The resistance is growing!!! @ruaaup-aft.bsky.social @aaup.bsky.social #celegans
February 19, 2025 at 10:16 PM
Reposted by Karen Schindler
luskinglab.bsky.social
Thank you for amplifying. Let’s GO New Haven!
February 18, 2025 at 9:24 PM
Reposted by Karen Schindler
ssrwinrs.bsky.social
Calling all postdoctoral WinRS! There's 1 more week left to apply for the L'Oreal Women in Science Fellowship! Click on the link in our linktree to apply by Feb. 14th #reprorocks #womeninstem #loreal💪
February 7, 2025 at 7:00 PM
Reposted by Karen Schindler
socdevbio.bsky.social
The Society for Developmental Biology has released a statement on the Unprecedented Disruptions to Biomedical Research in the United States.
Scientific research is a driving force behind human progress. It fuels medical breakthroughs, spurs technological innovations and drives economic growth. Federal funding of research by the National Institutes of Health (NIH) and the National Science Foundation (NSF) is absolutely critical for ensuring that the U.S. maintains its global leadership in science and technology. The unprecedented freeze on the review and issuance of federal research grants is already negatively impacting research and could have significant ripple effects. Ongoing studies may lose momentum if grant renewals or supplement requests are delayed, slowing scientific progress on research the NIH has already invested in. Researchers affiliated with the Society for Developmental Biology carry out critical research on birth defects, which kill twice as many children as cancer does. Slowed progress will delay the development of new therapies and diagnostics, and thus have real public health implications. In 2019, the total estimated cost of birth defect–associated hospitalizations was $22.2 billion. Scientific research is also critical to the U.S. economy more broadly. In 2023 alone NIH funded research not only directly supported 412 thousand jobs, but its overall economic impact rippled out to all sectors of the economy driving more than $92.89 billion in economic activity across all 50 U.S. states and the District of Columbia. It is estimated that every dollar of NIH funding generates $2.46 dollars of economic activity. Finally, federal research funding not only drives impactful research discoveries but also supports the training of the scientists, engineers, and innovators of the future. University laboratories, funded by federal grants, serve as essential training grounds for the next generation of researchers even as they push the boundaries of knowledge. This training prepares young scientists for leadership roles in both academia and industry, helping to ensure that the scientific workforce r…
January 29, 2025 at 10:08 PM
schindlerlab.bsky.social
Sharing some oocyte spindle love-an image taken by PhD student Phia Maddocks. This beautiful work is supported by our NIH funding. Without this funding, we cannot understand the complexities of fertility genetics. With declining fertility rates, this work is essential to human health.
January 29, 2025 at 9:42 PM
Reposted by Karen Schindler
ewelinabolcunf.bsky.social
⏰ Mark your calendars for TOMORROW, January 15, 2025, at 12:00 PM Eastern time, as we host a thought-provoking webinar led by Andrew Modzelewski with research talks from Devanshi Jain and Miguel Brieño-Enríquez 🧬 Sign Up Now: us02web.zoom.us/webinar/regist…
January 14, 2025 at 8:39 PM
schindlerlab.bsky.social
If you are interested in learning more about the MBL Frontiers in Reproduction course, consider zooming into our info sessions. The first one is tomorrow morning.
December 19, 2024 at 12:03 AM