Lightnews — Scholar-powered news

Reposted by Sebastiano Pasqualato

Nature @nature.com · 5d

This year’s Nobel Prize in Physiology or Medicine has been awarded to three scientists for discovering a class of immune cells that help to prevent the body from attacking its own tissues

go.nature.com/3VNrH1s

Medicine Nobel goes to scientists who revealed secrets of immune system ‘regulation’

Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi discovered cells that protect the body from autoimmune diseases.

go.nature.com

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Albert and Mary Lasker Foundation @laskerfdn.bsky.social · Sep 11

Congratulations to Dirk Görlich and Steven L. McKnight, 2025 #LaskerAward winners! - “for discoveries that exposed the structures and functions of low-complexity domains within protein sequences” 🧪
@mpi-nat.bsky.social
#Lasker2025 #LaskerLaureate #structuralbiology #phaseseparation

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Sebastiano Pasqualato @spasqualato.bsky.social · Sep 2

@gabrieleniola.bsky.social @ilpost.it vi segnalo questo errore in un vostro articolo. Nel film di Del Toro Waltz non è Pretorius, né uno scienziato che fa cose dopo la presunta morte del barone. Ciao e keep it up!

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Symposium on Structural Proteomics 2025 @ssp2025.bsky.social · Aug 27

Final days to get signed up for the Symposium on Structural Proteomics in Milan, 6-8 October! Registrations and abstract submissions for posters and talks still open until ❗this sunday August 31st!
@humantechnopole.bsky.social
Find out more at ssp2025.squarespace.com

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eLife @elife.bsky.social · Aug 26

This ‘landmark’ study describes the structural mechanism of strand exchange by the RAD51 filament using cryogenic structural, biochemical, and single-molecule analyses.
buff.ly/Ieh84gj

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Carter Lab @carter-lab.bsky.social · Aug 5

Excited to share our latest work with @simonbullock11.bsky.social! We looked at how diverse mRNAs get selected for subcellular localization and it turns out that a single protein can recognize different RNA elements using shared features that weren’t apparent before.
www.biorxiv.org/content/10.1...

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Human Technopole @humantechnopole.bsky.social · Jul 24

🧬 We're excited to host the 13th Symposium on Structural #Proteomics at HT in Milan on 6–8 Oct 25! Join this international meeting with talks on protein structure and interactions by crosslinking MS, HDX-MS, native MS, chemoproteomics & more 👉 ssp2025.squarespace.com
▶️ @ssp2025.bsky.social

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Brittany Trang @brittanytrang.com · Jul 21

NEW from me at STAT:

We've learned that DeepMind is going to fund CASP, the protein structure competition that brought Google DeepMind's #AlphaFold to prominence (and a Nobel Prize), as its NIH funding runs out.

More @statnews.com:
www.statnews.com/2025/07/21/c...

🖥️🩺🧪🧬 #bioML

AlphaFold developer Google DeepMind to fund CASP as NIH funding falls short

Protein structure prediction contest CASP gets temporary funding from Google DeepMind as NIH grant runs out.

www.statnews.com

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Molecular Cell @cp-molcell.bsky.social · Jul 3

Online Now: Condensin II activation by M18BP1 Online now:

Condensin II activation by M18BP1

Borsellini, Conti, Cutts, Harris, et al. identify an interaction between M18BP1 and condensin II that is essential for condensin II activity and chromatin localization. MCPH1 keeps the interphase genome uncondensed by competing with M18BP1. A phosphorylation-driven switch allows M18BP1 to trigger condensation at mitotic onset.

dlvr.it

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Sergio Cruz-León @sergiocruzleon.bsky.social · Apr 11

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social,
@marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social

🔗 Preprint here tinyurl.com/3a74uanv

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Human Technopole @humantechnopole.bsky.social · Apr 8

🔴 Registrations are open! Join us at OPEN HT, a day dedicated to #lifesciences research, on the occasion of the 10th anniversary of the MIND district.

Register by 15 April 👉 humantechnopole.it/en/trainings...

The event will be held in Italian.

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Sebastiano Pasqualato @spasqualato.bsky.social · Feb 20

As always, excellent talk by Alessandro Borsellini from @alessandrovannini.bsky.social Lab, at @humantechnopole.bsky.social, showcasing his work at the 6th AIC-BMM meeting in Firenze! #associazioneitalianacristallografia sezione macromolecole biologiche

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Sebastiano Pasqualato @spasqualato.bsky.social · Feb 18

Please, reach out if you have complex inquiries or even naïve questions about the application process... or any other matter!

Sebastiano Pasqualato @spasqualato.bsky.social · Feb 18

The new Call for Access to services provided by the National Facilities of Human Technopole is online!
Check out our *new services*!
Fully funded access to services, including consumables, as well as complete access to HT and training (for services for which it is applicable)

Human Technopole @humantechnopole.bsky.social · Feb 17

🚀 The first 2025 Call for Access for our National Facilities is now open! Researchers can apply for cutting-edge services in the fields of omics, imaging and data analysis. Submit your proposal by 31 May!

Apply here 👉 humantechnopole.it/en/national-...

National Facilities - Human Technopole

humantechnopole.it

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Paolo Swuec @pscryoem.bsky.social · Jan 29

Great to have @martinpacesa.bsky.social as invited speaker to our weekly Structural Biology Colloquia. Such a solid, functional and impactful workflow 🤩. Thanks a lot for coming!

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Paolo Swuec @pscryoem.bsky.social · Jan 13

A real milestone for the local community, today we celebrate the beginning of service provision by @humantechnopole.bsky.social National Facility for Structural Biology. Lucky to have a smiling @luigiscietti.bsky.social (in pic with our Gaetano D'Urso) from IEO as first user to the Cryo-EM Unit.

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Paolo Swuec @pscryoem.bsky.social · Jan 15

Excited to see the first batch of biomass safely delivered from our National Facility for Structural Biology @humantechnopole.bsky.social to Filippo Acconcia of Università Roma Tre. A big thank you to our stellar Biomass Unit, onward to more milestones!

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il Post @ilpost.it · Jan 9

Abbiamo due notizie: riguardano Luca Sofri e Francesco Costa. Insomma, al Post cambieranno un po' di cose. Le raccontano qui i diretti interessati (anzi, ora possiamo dire: i direttori interessati)

ilpost.link/e1oRRcnU1t

Le nuove direzioni del Post - Il Post

Innovare nella tradizione!

ilpost.link

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Alessandro Vannini @alessandrovannini.bsky.social · Jan 3

Excited to share the (hard) work of @zawarshah.bsky.social in its final form: www.nature.com/articles/s41...

A lot of insights into RNA Polymerase selectivity at snRNAs promoters !! As these promoters are often used for heterologous expression of RNAs (ie guide RNAs), you better know how they work

Structural insights into distinct mechanisms of RNA polymerase II and III recruitment to snRNA promoters - Nature Communications

The snRNA Activating Protein Complex (SNAPc) mediates snRNA transcription by RNA Pol II and III. Here, the authors have used cryo-EM to resolve the structure of the SNAPc-bound RNA Pol III pre-initiat...

www.nature.com

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PastelBio @pastelbio.bsky.social · Jan 7

Human Technopole - Technician/Senior Technician in Structural Proteomics careers.humantechnop...

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#proteomics #prot-jobs

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Sebastiano Pasqualato @spasqualato.bsky.social · Dec 21

Wishing everybody a great holiday season form the staff of the National Facility for Structural Biology of @humantechnopole.bsky.social! It’s been a wild year getting things started and opening to the Italian community, but it’s also been wild fun, with these amazing people! Have a great time!

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Kasia Tych @biophysk.bsky.social · Dec 6

Calling all #SciComm people who specialise in scientific animations. I would like to talk to someone about making some animations to communicate our research in single-molecule biophysics. Please message me if you are interested and share with your networks! 🧪

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Sebastiano Pasqualato @spasqualato.bsky.social · Dec 5

All detail about the job position, and how to apply, here: careers.humantechnopole.it/o/technician...

Human Technopole - Technician/Senior Technician in Structural Proteomics

APPLICATION CLOSING DATE: 18 January 2025 About the Institute Human Technopole (HT) is an interdisciplinary life science research institute, created and supported by the Italian government, with the a

careers.humantechnopole.it

Sebastiano Pasqualato @spasqualato.bsky.social · Dec 5

Join an exciting scientific environment, an amazing integrated structural biology research centre, a thriving and booming young life science institute, in a wonderful facility led by @pscryoem.bsky.social 2/3

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Sebastiano Pasqualato @spasqualato.bsky.social · Dec 5

JOB ALERT!!! The National Facility for Structural Biology at @humantechnopole.bsky.social is HIRING!! BlueSky-less Andrea Graziadei is looking for a technician to join his Unit and push #structuralproteomics to new, uncharted territories!! 1/3

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