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standverytall.bsky.social
@standverytall.bsky.social
cancer patient, small biz owner, loves traveling and studying languages and cultures.
Elicio ELI-002 2P: G12D G12R / ELI-002 7P: G12D G12R G12V G12A G12C G12S G13D. Preventing recurrence / delaying progression, not shrinking metastases, even though early signals are encouraging. Phase 2 mostly limited to pancreatic patients. CRC expansion cohorts planned at MD Anderson, UCLA, MSK ..
GOOD NEWS! A new cancer vaccine has shown progress in triggering POWERFUL and LASTING immune responses in patients with pancreatic AND colorectal cancer. The vaccine, known as ELI-002 2P, targets mutant KRAS proteins AND had a huge impact on PREVENTING or DELAYING cancer recurrence in patients.
October 26, 2025 at 6:34 PM
NCT05425940 - Exelixis STELLAR-303, OS 10.9 vs 9.4, Hazard Ratio 0.8 for both KRAS mutant and KRAS WT. FDA approval expected in late 2026 based on late 2025 regulatory application.
ir.exelixis.com/news-release...
Exelixis Announces Detailed Results from Phase 3 STELLAR-303 Pivotal Trial Evaluating Zanzalintinib in Combination with an Immune Checkpoint Inhibitor in Metastatic Colorectal Cancer Presented at ESMO...
The Investor Relations website contains information about Exelixis, Inc.'s business for stockholders, potential investors, and financial analysts.
ir.exelixis.com
October 23, 2025 at 6:00 PM
NCT05425940 - Exelixis STELLAR-303, Hazard Ratio 0.8 for both KRAS mutant and KRAS WT. FDA approval expected in late 2026 based on late 2025 regulatory application.
✨#ESMO25✨

🚨 BREAKING: STELLAR-303 Phase 3 Update!

💊 Zanzalintinib + Atezolizumab (Tecentriq®) improved median OS to 10.9 months vs 9.4 months with regorafenib in metastatic colorectal cancer.

📈 The combination demonstrated a notable survival advantage in the intention-to-treat population.
October 23, 2025 at 5:46 PM
Reposted
✨#ESMO25✨

🚨 BREAKING: STELLAR-303 Phase 3 Update!

💊 Zanzalintinib + Atezolizumab (Tecentriq®) improved median OS to 10.9 months vs 9.4 months with regorafenib in metastatic colorectal cancer.

📈 The combination demonstrated a notable survival advantage in the intention-to-treat population.
October 20, 2025 at 2:30 PM

Fate plays with people, president or not. Upon Biden’s arrival, the Taliban waxed. Upon his departure, Syria waned. Trump must feel a bit less Trump: Biden knows how to play his trump.

命运弄人,哪管你是不是总统?拜登甫上任,塔利班摧枯拉朽,让他颜面尽失。即将卸任,叙利亚叛军却排山倒海,让他光荣还乡。 特朗普有点儿眼馋: 肥肉怎可掉拜登?
December 8, 2024 at 7:15 AM
Reposted
来到Bluesky,是对马斯克的无声抗议,我将这里的人都看成持共同理念的同胞,作为一种courtesy,所有fo我的人我都回fo;骂川普八年也骂累了,分享了一些个人生活感悟。结果引开大量骗子,不得不关闭私聊。还是得彻底清理一下关注,也请那些放张美女头像的别再fo我,我一把年纪了,早已油盐不进、片叶不沾。Bluesky也得下点功夫清理门户,别像X那样乌烟瘴气,最终会影响平台声誉。
December 8, 2024 at 4:08 AM
Reposted
👏
December 2017, exactly 7 years ago, Putin flew to Syria and stated:

"If the terrorists raise their heads again, we will strike them [from the Russian bases in Syria] in a way that they have not yet seen."

Today, the Russian army is evacuating from Tartus and Khmeimim and fleeing Syria.
December 8, 2024 at 4:39 AM
Reposted
(413)
#Nightingale
“If I could give you information of my life, it would be to show how a woman of very ordinary ability has been led by God in strange and unaccustomed paths to do In His service what He ha...

#Quotes #aphorisms #Lifelong #Learning #Life #Lessons
“If I could give you information of my life, it would be to show how a woman of very ordinary ability has been led by God in strange and unaccustomed paths to do In His service what He ha... - Nightingale
In this quote, Florence Nightingale reflects on the humility and divine guidance that shaped her life and work. She acknowledges that, by worldly standards, she may have been a woman of ordinary ability, yet she believes that it was through God’s guidance that she was led to accomplish extraordinary things in the field of nursing and public health. Nightingale’s words emphasize that her achievements were not the result of her own power or exceptional talents, but rather a manifestation of God’s will working through her. This perspective reveals her deep sense of faith and humility, where she attributed her success not to her own efforts, but to a higher purpose that directed her path.
note.en.lv73.net
December 7, 2024 at 11:34 PM
梅洛尼和马斯克今天于巴黎再次相见。

Meloni and Musk saw each other again in Paris.
December 8, 2024 at 2:51 AM
大概六百万叙利亚人因为内战逃亡他国。现政府倒台之后,有多少难民会重新回到这个国家,重建家园?

About six million Syrians have fled the civil war. How many of them will return to rebuild their homes after the current government falls?
December 8, 2024 at 2:30 AM
大马士革传来的视频,似乎显示军人开始逃离。
DAMASCO:

En el corazón de Damasco, cunde el pánico en este momento en la zona de Malki. La residencia principal de Assad se encuentra aquí, la zona está fortificada por las fuerzas del régimen que ahora están huyendo.

Esto muestra claramente que el régimen se está desmoronando en sus cimientos.
DAMASCUS:

In the heart of Damascus, panic this moment in the Malki area. Assad's main residence is located here, the area is fortified with regime forces that are now fleeing.

This is clearly the regime falling apart at it's very core.
December 8, 2024 at 2:20 AM
韩国前防长因为参与戒严被羁留。

Former South Korean defense minister detained for executing the martial law order.
December 8, 2024 at 2:12 AM
Reposted
México lindo y querido tiene la Peña de Bernal en Querétaro, el tercer más grande monolito en el mundo.
Peña de Bernal Querétaro.
December 8, 2024 at 1:36 AM
看泽连斯基的个人魅力了。

Shine, Zelensky, shine.
December 8, 2024 at 2:03 AM
左边柱子:唐纳德到此一游。

Pillar on the left.
#NotreDame ‘s Grand Reopening © Chappatte in Le Temps, Geneva 👉 www.chappatte.com
December 7, 2024 at 8:21 PM
最近看到一些关于医保的讨论,我能够理解大家的不满,但是如果影射这是医院玩黑,我无法接受。

我两三周看一次医生,接受化疗,两个月照一次光片,大小手术都做过,接触到无数的医护人员。我对他们只有尊敬和感激,他们是白衣天使,蓝衣天使。

与其说医院坏,不如说它们乱。一个重要原因是乱定价格。理论上市场决定价格。但是现实里保险只保个别机构,又和它们有单独的协议。顾客一年只能做一次选择,而生病之后往往没有时间或者不合实际去比较价格。这些都限制了市场规范价格的自由和能力。
December 7, 2024 at 7:22 PM
不是所有的华人都那么不堪。我是餐馆老板。我用的是奥巴马健保。我受益于特朗普在任时期的个人减税政策。餐馆如果没有特朗普任内开始的心冠救助计划和针对小型公司20%盈利免税的政策也不可能生存。但是我从来没有投票给特朗普。

另外评论里有人指责我们不给员工买保险也不准确。我们之前给自己和经理买的是私人医保。餐馆大部分工人不是全职(我们只开晚餐),无法上医保。全职员工我们问过,但是他们都是年轻的西裔,不愿自己出保费(虽然餐馆会支付大部分)。最近经理离开,保险公司将我们的费用涨了3倍,餐馆实在无法承担。所以我们选择放弃,加入奥巴马健保。实际上,市面上根本没有小餐馆可以选择的好计划。我们也是有心无力。
我真的會找幾個出來,因為我認識的做餐館的有好些有奧巴馬醫保,他們一般都投給黃毛,不過由於共和黨微弱優勢,或許不會刮掉他們的醫保,但如果真正跟他們談起這個性命攸關的事情,他們會以廁所問題搪塞,因為他們是單一議題投票者,別人努力保護他們的利益他們不在乎,搭便車是我們漢字從清高的書生到販夫走卒都樂意幹的。
December 7, 2024 at 6:48 PM
1867成立,后被降级,1979恢复,最小的联邦部门之一,教育部会成为即将上任的精简沙皇的“祭品”吗?

Created in 1867 and demoted in 1868, the Education Department was not restored until 1979. As a tiny department, employing fewer than 5,000 workers, it is an easy target for the incoming Czar of government efficiency, eager to add to his kills.
The Rise and Rapid Fall of the First US Department of Education

The department, established in 1867, faced opposition from Southern congressmen, who associated it with education for the formerly enslaved. 🗃️

www.history.com/news/departm...
The Rise and Rapid Fall of the First US Department of Education | HISTORY
The department, established in 1867, faced opposition from Southern congressmen, who associated it with education for the formerly enslaved.
www.history.com
December 7, 2024 at 6:35 AM
Reposted
December 7, 2024 at 3:36 AM
石正丽借日本学术会议展示武汉研究所冠状病毒序列,希望证明实验室样本与 COVID 病毒没有近亲关系。她的分析还未经过同行评审。

Shi Zhengli presents the Wuhan Institute's coronavirus sequence, at a conference in Japan, hoping to debunk the theory that the COVID virus was leaked from the Wuhan laboratory. Her analysis has not yet been peer-reviewed.
"En una conferencia en Japón esta semana, Shi Zhengli, una especialista en coronavirus de murciélagos, reportó que ninguno de los virus almacenados en sus congeladores son los ancestros más recientes del virus SARS-Cov-2."

www.nature.com/articles/d41...
Wuhan lab samples hold no close relatives to virus behind COVID
Shi Zhengli, the virologist at centre of COVID lab-leak theory, reveals coronavirus sequences from Wuhan institute.
www.nature.com
December 7, 2024 at 5:19 AM
Reposted
什麼是文化大革命?
我畢業中央美院,文革被押到豐台燒磚廠勞改。一天,在工地,看到一流浪狗,很 瘦,那期待的眼神頓時融化了我近乎冷卻的心,我收養了 它。
我們每天發三個窩頭、三碗菜湯,我還 是省下三分之一窩頭給狗吃。突然一天, 造反派把我押到台上,打倒在地,用帶著鐵頭的皮帶雨點似地抽打我,我痛得幾乎昏死過去。這時,狗突然躥了過來,死死地趴在我身上,用它那瘦弱的身軀抵擋皮帶的抽打,一動不動.......
天黑了,批鬥結束,人們都走了,我翻身坐起, 狗狗還在我身上,可是它的腰己經被打斷, 死去......
我抱著它放聲大哭
我挖了坑,把它埋了,插了一塊小牌 子,寫了幾個字:「快點託生回到我的懷 抱」
December 7, 2024 at 2:35 AM
The University of Santiago, a top school in Spain, abandons its X account because it considers that the social network promotes racism and misogyny.

X 还在流血:西班牙最古老的大学之一选择放弃平台,认为平台助长种族歧视和性别歧视。
December 6, 2024 at 10:46 PM