The Lancet Diabetes & Endocrinology
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The Lancet Diabetes & Endocrinology
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Your leading source of international, cutting-edge research, review, and opinion in clinical #diabetes and #endocrinology. IF=41·8.

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The Lancet is a weekly peer-reviewed general medical journal, founded in England in 1823. It is one of the world's highest-impact academic journals and also one of the oldest medical journals still in publication. .. more

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Read our December Issue, featuring familial hypercholesterolaemia, chronic kidney disease, type 2 diabetes, cyclic Cushing’s syndrome, primary aldosteronism, type 1 diabetes, menopause, obesity, iodine deficiency, & much more tinyurl.com/mwfu4c6m

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New—Glycaemic control and pregnancy outcomes with real-time continuous glucose monitoring in #gestational #diabetes (GRACE): an open-label, multicentre, multinational, randomised controlled trial thelancet.com/journals/lan...
#CGM

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Glycaemic control and pregnancy outcomes with real-time continuous glucose monitoring in gestational diabetes (GRACE): an open-label, multicentre, multinational, randomised controlled trial
rt-CGM use in women with gestational diabetes reduced LGA births, without differences in serious adverse events. The higher-than-expected overall prevalence of SGA infants, possibly related to the tig...
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Non-coeliac gluten sensitivity (NCGS) remains a highly debated condition, despite ~10% of the global population self-reporting a gluten or wheat sensitivity.

A Review examines current evidence & provides practical guidance for assessment and management: spkl.io/63328AdQha

Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice thelancet.com/journals/lan... #MEN1
#FREE to read with registration (also FREE)

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Multiple endocrine neoplasia type 1 (MEN1): recommendations and guidelines for best practice
Multiple endocrine neoplasia type 1 (MEN1) is characterised by combined occurrence of parathyroid tumours, duodenopancreatic neuroendocrine tumours, and anterior pituitary adenomas. Some patients migh...
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Peripartum cardiomyopathy is now the leading cause of maternal death in many parts of the world.

A Seminar summarises current knowledge of peripartum cardiomyopathy genetics, pathophysiology, diagnostic approaches, medical management, and outcome: spkl.io/63320AdQNn

Adrenal tumour imaging: clinical, molecular, and radiomics perspectives thelancet.com/journals/lan...
#adrenal #tumour

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New—In Focus with Talha Burki:
Getting smart about the food we eat thelancet.com/journals/lan...
ultra-processed foods #UPFs #obesity
#FREE to read with registration (also FREE)

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Getting smart about the food we eat
In April 2025, Kevin Hall took early retirement from the US National Institutes of Health (NIH). “My life's work has been to scientifically study how our food environment affects what we eat, and how ...
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788 million people worldwide were living with chronic kidney disease in 2023. Yet neither awareness nor action match the threat posed to health.

Our latest Editorial ➡️ "Chronic kidney disease: breaking the silence" spkl.io/63324AdQLO

"We present 25 questions on the most important aspects of the clinical management of adult patients with #adrenocortical #carcinoma that we have frequently asked ourselves over the past 25 years" www.thelancet.com/journals/lan...
#OpenAccess

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Adrenocortical carcinoma: a practical guide for clinicians
Adrenocortical carcinoma is a rare endocrine malignancy. The management of patients with adrenocortical carcinoma is challenging for several reasons, including its heterogeneous but frequently aggress...
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The effect of #overdiagnosis has been so pronounced that it has changed the global epidemiological landscape of #thyroid #cancer among adolescents and young adults (AYAs), mirroring patterns in older adults www.thelancet.com/journals/lan...
#thyroidcancer

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Portion sizes and caloric inequity: a hidden driver of obesity disparities www.thelancet.com/journals/lan...
#obesity
#FREE to read

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The application of implementation science to expanding knowledge of #familial #hypercholesterolaemia has enabled the development and design of potentially more effective models of care www.thelancet.com/journals/lan...
#ASCVD #cholesterol

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Jonathan Pearson-Stuttard & Julia A Critchley comment on:
Heterogeneity in type 2 #diabetes trajectories: informing public health approaches www.thelancet.com/journals/lan... #T2D #cancer
#FREE to read with registration (also FREE)

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Heterogeneity in type 2 diabetes trajectories: informing public health approaches
In The Lancet Diabetes & Endocrinology, Francesco Zaccardi and colleagues1 provide a thoughtful analysis of transitions to type 2 diabetes and cancer development and mortality among 330 000 people liv...
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Tommaso Porcellia & Martin Schlumberger comment on:
The rise of thyroid cancer incidence in adolescents and young adults thelancet.com/journals/lan...
#thyroid #cancer

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The rise of thyroid cancer incidence in adolescents and young adults
In The Lancet Diabetes & Endocrinology, Mengmeng Li and colleagues analysed global trends in thyroid cancer incidence from 2003 to 2017 and contemporary burden for the year 2022 among adolescents and ...
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New—Thyroid cancer in adolescents and young adults: a population-based study in 185 countries worldwide thelancet.com/journals/lan...
#thyroid #cancer

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#SGLT2 inhibition reduces risk of acute and chronic #kidney outcomes irrespective of the size of the acute dip in eGFR. Kidney benefits are evident irrespective of diabetes status, heart failure status, primary cause of kidney disease, and markers of severity of these diseases tinyurl.com/m9jmk592.
Effects of empagliflozin on conventional and exploratory acute and chronic kidney outcomes: an individual participant-level meta-analysis
SGLT2 inhibition reduces risk of acute and chronic kidney outcomes irrespective of the size of the acute dip in eGFR. Kidney benefits are evident irrespective of diabetes status, heart failure status,...
tinyurl.com
Ultra-processed foods – what’s the impact?

In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat.

Read the evidence & policy recommendations ⬇️
spkl.io/63327AduhR

#Adrenal tumours have become a common incidental finding in the radiological evaluation of patients. Estimates suggest that 1–10% of the general population currently harbours an adrenal tumour, peaking in prevalence in the seventh and eighth decades of life thelancet.com/journals/lan...

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Life stage transitions for people with type 1 #diabetes www.thelancet.com/journals/lan... #T1D

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#Adrenal #tumours are commonly encountered in every endocrinology practice & related subspecialties nowadays, & require the most accurate evidence-based management, treatment, and follow-up thelancet.com/journals/lan...
#phaeochromocytoma #paraganglioma #adrenocortical #carcinoma

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New—Adrenal tumour imaging: clinical, molecular, and radiomics perspectives thelancet.com/journals/lan...
#adrenal #tumour #phaeochromocytoma #paraganglioma #adrenocortical #carcinoma

#MedSky #EndoSky #OncSky

People with #diabetes face many challenges in the #workplace and have specific needs; however, these are often overlooked, and available support structures are either inadequate or absent
thelancet.com/journals/lan...
#FREE to read

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The high prevalence of #comorbidities at the time of diagnosis of #diabetes in the severe insulin-resistant diabetes #subgroup signals a need for earlier identification & an unmet need for early intensified diabetes treatment of this population thelancet.com/journals/lan...
#PrecisionMedicine
Comorbidities and mortality in subgroups of adults with diabetes with up to 14 years follow-up: a prospective cohort study in Sweden
Diabetes subgroups could inform on outcomes, as well as guide treatment and follow-up needed for newly diagnosed individuals with diabetes. SIRD stands out as a high-risk subgroup that is not identifi...
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Sporadic #prolactinomas are the most common functioning #pituitary adenomas, with a female predominance during reproductive years. In men, these adenomas are usually larger and more aggressive www.thelancet.com/journals/lan...
#hyperprolactinaemia

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