Joanne C Masterson
@themastersonlab.bsky.social
Mucosal cell biologist. Interested in mucosal immunobiology #Epithelial #barrier #regeneration #remodeling #hypoxia #metabolism #EoE #WomenInSTEM #FirstGen Mom of 3 ❤️ ☘️ Professor @ Maynooth University, University of Colorado, Children’s Hospital
Huge congratulations to rock 💫 Shauna Kellett from my lab publishing her @ResearchIreland funded MSc(Res) 🎉
showing that #HIF-1α-CD73-adenosine signaling axis is important in the resolution of #EoE associated #epithelial dysfunction
www.sciencedirect.com/science/arti...
showing that #HIF-1α-CD73-adenosine signaling axis is important in the resolution of #EoE associated #epithelial dysfunction
www.sciencedirect.com/science/arti...
Resolution of epithelial dysfunction in eosinophilic esophagitis is mediated by an HIF-1α-CD73-adenosine signaling axis
Inflammatory hypoxia is induced by eosinophilic inflammation, while a decreased expression in the key hypoxic regulator, hypoxia-inducible transcripti…
www.sciencedirect.com
October 20, 2025 at 7:09 PM
Huge congratulations to rock 💫 Shauna Kellett from my lab publishing her @ResearchIreland funded MSc(Res) 🎉
showing that #HIF-1α-CD73-adenosine signaling axis is important in the resolution of #EoE associated #epithelial dysfunction
www.sciencedirect.com/science/arti...
showing that #HIF-1α-CD73-adenosine signaling axis is important in the resolution of #EoE associated #epithelial dysfunction
www.sciencedirect.com/science/arti...
It’s a privilege & thrill to watch rockstar 💫 @maynoothuniversity.ie PhD student @shaunakellett.bsky.social present her @researchireland.ie funded
MScRes to International Eosinophil Society on CD73/ADO in epithelial dysfunction in Eosinophilic Esophagitis #EoE
Fantastic #ECRs conference 🎉
#ProudPI
MScRes to International Eosinophil Society on CD73/ADO in epithelial dysfunction in Eosinophilic Esophagitis #EoE
Fantastic #ECRs conference 🎉
#ProudPI
July 10, 2025 at 2:02 PM
It’s a privilege & thrill to watch rockstar 💫 @maynoothuniversity.ie PhD student @shaunakellett.bsky.social present her @researchireland.ie funded
MScRes to International Eosinophil Society on CD73/ADO in epithelial dysfunction in Eosinophilic Esophagitis #EoE
Fantastic #ECRs conference 🎉
#ProudPI
MScRes to International Eosinophil Society on CD73/ADO in epithelial dysfunction in Eosinophilic Esophagitis #EoE
Fantastic #ECRs conference 🎉
#ProudPI
Reposted by Joanne C Masterson
For World Eosinophilic Esophagitis Day, we’ve curated a list of recent #EoE articles from across the journal portfolio:
🟣 ow.ly/Qjlo50VXmVx
🟣 ow.ly/UrEV50VXmVy
🟣 ow.ly/rkVL50VXmVw
🟣 ow.ly/JibY50VXmVz
🟣 ow.ly/Fr9950VXmVA
#EoEDay
@amergastroassn.bsky.social
🟣 ow.ly/Qjlo50VXmVx
🟣 ow.ly/UrEV50VXmVy
🟣 ow.ly/rkVL50VXmVw
🟣 ow.ly/JibY50VXmVz
🟣 ow.ly/Fr9950VXmVA
#EoEDay
@amergastroassn.bsky.social
May 22, 2025 at 7:37 PM
For World Eosinophilic Esophagitis Day, we’ve curated a list of recent #EoE articles from across the journal portfolio:
🟣 ow.ly/Qjlo50VXmVx
🟣 ow.ly/UrEV50VXmVy
🟣 ow.ly/rkVL50VXmVw
🟣 ow.ly/JibY50VXmVz
🟣 ow.ly/Fr9950VXmVA
#EoEDay
@amergastroassn.bsky.social
🟣 ow.ly/Qjlo50VXmVx
🟣 ow.ly/UrEV50VXmVy
🟣 ow.ly/rkVL50VXmVw
🟣 ow.ly/JibY50VXmVz
🟣 ow.ly/Fr9950VXmVA
#EoEDay
@amergastroassn.bsky.social
#ProudPI #VivaDone
…and from out of the box emerged the most brilliant scientist you’d ever seen, Dr Louise Crowe
Beyond thrilled. Very many congratulations Louise. 🎉
Many thanks to Dania Movia and Desmond Tobin for a robust viva
Another 💫 from the #AIRRLab Maynooth University & MULonsdale
…and from out of the box emerged the most brilliant scientist you’d ever seen, Dr Louise Crowe
Beyond thrilled. Very many congratulations Louise. 🎉
Many thanks to Dania Movia and Desmond Tobin for a robust viva
Another 💫 from the #AIRRLab Maynooth University & MULonsdale
May 3, 2025 at 11:06 AM
Congrats Olga Fagan Superstar MD student 💫
Important update on the #RareDisease that is very much a growing problem in Irish adults, Eosinophilic Esophagitis #EoE #allergy
Gratitude to collaboration between @MaynoothUni & @stjamesdublin & to @hrbireland for supporting this.
Important update on the #RareDisease that is very much a growing problem in Irish adults, Eosinophilic Esophagitis #EoE #allergy
Gratitude to collaboration between @MaynoothUni & @stjamesdublin & to @hrbireland for supporting this.
Eye-opening study on Eosinophilic Oesophagitis in Irish adults! 🇮🇪
Real-world oesophageal biopsy approaches in EoE are often suboptimal and may contribute to delayed diagnosis.
onlinelibrary.wiley.com/doi/10.1111/...
Real-world oesophageal biopsy approaches in EoE are often suboptimal and may contribute to delayed diagnosis.
onlinelibrary.wiley.com/doi/10.1111/...
Eosinophilic Oesophagitis in Adults: National Centre Retrospective Study in an Irish Cohort
Click on the article title to read more.
onlinelibrary.wiley.com
April 24, 2025 at 7:51 AM
Congrats Olga Fagan Superstar MD student 💫
Important update on the #RareDisease that is very much a growing problem in Irish adults, Eosinophilic Esophagitis #EoE #allergy
Gratitude to collaboration between @MaynoothUni & @stjamesdublin & to @hrbireland for supporting this.
Important update on the #RareDisease that is very much a growing problem in Irish adults, Eosinophilic Esophagitis #EoE #allergy
Gratitude to collaboration between @MaynoothUni & @stjamesdublin & to @hrbireland for supporting this.
Reposted by Joanne C Masterson
A study in Nature Medicine exposed LLMs to simulated clinical cases with switched sociodemographic features exploring ethnic, social, sexual orientation and gender dimensions and showed differences in recommendations for patient treatment, referral and follow-up based only on these features. 🔒
Sociodemographic biases in medical decision making by large language models - Nature Medicine
A panel of nine LLMs was exposed to simulated clinical cases with switched sociodemographic features exploring ethnic, social, sexual orientation and gender dimensions and showed differences in recommendations for patient treatment, referral and follow-up based only on these features.
go.nature.com
April 13, 2025 at 10:11 PM
A study in Nature Medicine exposed LLMs to simulated clinical cases with switched sociodemographic features exploring ethnic, social, sexual orientation and gender dimensions and showed differences in recommendations for patient treatment, referral and follow-up based only on these features. 🔒
It was great to be invited by Research Ireland as a panelist for these thought provoking events & to hear such encouragement from minister James Lawless regarding the appetite for collaboration and engagement regarding the future of research & its continued importance in Ireland.
This week, Minister James Lawless addressed the audience at a Research Ireland stakeholder consultation event. He acknowledged and thanked stakeholders for their invaluable contributions throughout the nationwide consultation programme. #ResearchIreland
April 5, 2025 at 10:01 AM
It was great to be invited by Research Ireland as a panelist for these thought provoking events & to hear such encouragement from minister James Lawless regarding the appetite for collaboration and engagement regarding the future of research & its continued importance in Ireland.
This days purpose is to achieve full & equal access & participation of girls & #WISTEM.
I will continue to do my utmost to promote this. In ever challenging times, I especially celebrate those women who lifted me up, pushed me onwards and who continue to my support.
Let’s continue to #PayItForward
I will continue to do my utmost to promote this. In ever challenging times, I especially celebrate those women who lifted me up, pushed me onwards and who continue to my support.
Let’s continue to #PayItForward
February 12, 2025 at 5:28 AM
This days purpose is to achieve full & equal access & participation of girls & #WISTEM.
I will continue to do my utmost to promote this. In ever challenging times, I especially celebrate those women who lifted me up, pushed me onwards and who continue to my support.
Let’s continue to #PayItForward
I will continue to do my utmost to promote this. In ever challenging times, I especially celebrate those women who lifted me up, pushed me onwards and who continue to my support.
Let’s continue to #PayItForward
This is a fantastic opportunity to advance your career with a powerhouse of women in GI Sciences! Sign up today!!
If you are female PhD faculty in #GIresearch ( #basicscience or #translational), we invite you to join WINGS, Women Innovating in Gastrointestinal Science, a community for career development, mentorship & networking. Please fill out the form on our website and RT! bit.ly/4fHBWfj #GISky #Gastrosky
WINGS | edelblumlab
Women Innovating in Gastrointestinal Science is a group of basic & translational GI researchers that provides a community to connect, empower and inspire female faculty.
www.edelblumlab.com
January 6, 2025 at 10:07 PM
This is a fantastic opportunity to advance your career with a powerhouse of women in GI Sciences! Sign up today!!
Reposted by Joanne C Masterson
Count down: The 5 top accessed research manuscripts of 2024!
#4: AARS1 senses lactate and acts as a lactyl-transferase to promote YAP signaling in gastric cancer
https://www.jci.org/articles/view/174587
#4: AARS1 senses lactate and acts as a lactyl-transferase to promote YAP signaling in gastric cancer
https://www.jci.org/articles/view/174587
December 28, 2024 at 2:30 PM
Count down: The 5 top accessed research manuscripts of 2024!
#4: AARS1 senses lactate and acts as a lactyl-transferase to promote YAP signaling in gastric cancer
https://www.jci.org/articles/view/174587
#4: AARS1 senses lactate and acts as a lactyl-transferase to promote YAP signaling in gastric cancer
https://www.jci.org/articles/view/174587
Reposted by Joanne C Masterson
After we reach advanced age, around 80, the propensity to develop cancer is markedly reduced. A discovery reported at Nature today about aged stem cells and iron insufficiency may help explain this advantage
www.nature.com/articles/d41...
www.nature.com/articles/d41...
December 4, 2024 at 6:06 PM
After we reach advanced age, around 80, the propensity to develop cancer is markedly reduced. A discovery reported at Nature today about aged stem cells and iron insufficiency may help explain this advantage
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Joanne C Masterson
November 29, 2024 at 10:36 PM
Reposted by Joanne C Masterson
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
November 25, 2024 at 12:38 PM
Women are under-represented at senior levels in #academia globally, & across all #science 🧪 disciplines, as shown by these "scissor-shaped curves" ✂️
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
So how can we ever achieve #gender #equality?
We discuss various strategies in this #Cell Commentary
#WomeninSTEM
www.cell.com/cell/fulltex...
🧵 1/
Reposted by Joanne C Masterson
!!!
❗ Exciting news: AGA's journals are now on #bsky! 🤯 Give them a follow to make sure you know the latest in GI!
Gastroenterology 👉🏼 @aga-gastro.bsky.social
CGH 👉🏼 @aga-cgh.bsky.social
CMGH 👉🏼 @aga-cmgh.bsky.social
TIGE 👉🏼 @aga-tige.bsky.social
Gastro Hep Advances 👉🏼 @aga-ghadvances.bsky.social
Gastroenterology 👉🏼 @aga-gastro.bsky.social
CGH 👉🏼 @aga-cgh.bsky.social
CMGH 👉🏼 @aga-cmgh.bsky.social
TIGE 👉🏼 @aga-tige.bsky.social
Gastro Hep Advances 👉🏼 @aga-ghadvances.bsky.social
November 25, 2024 at 9:22 PM
!!!
Delighted to have been recognised in this '25 scientists you need to know about' piece. Honored to be amongst such amazing Irish Scientists 💫
@maynoothuni.bsky.social
#IrishResearch
@maynoothuni.bsky.social
#IrishResearch
From planetary defence and counterfeit fossils to sustainable sensors and novel drug discovery methods, we’re celebrating #ScienceWeek with a list of some of the most original thinkers working in Ireland’s research institutions right now. www.siliconrepublic.com/innovation/s...
25 scientists you need to know about
To celebrate Science Week, we’ve put together a bumper list of 25 scientists based in Ireland who are innovating across STEM.
www.siliconrepublic.com
November 25, 2024 at 6:04 PM
Delighted to have been recognised in this '25 scientists you need to know about' piece. Honored to be amongst such amazing Irish Scientists 💫
@maynoothuni.bsky.social
#IrishResearch
@maynoothuni.bsky.social
#IrishResearch
Reposted by Joanne C Masterson
The science version of “what doesn’t kill me makes me stronger”: Scientists with ‘near misses’ early in their careers outperform those with ‘narrow wins’ in the longer run.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 25, 2024 at 3:05 AM
The science version of “what doesn’t kill me makes me stronger”: Scientists with ‘near misses’ early in their careers outperform those with ‘narrow wins’ in the longer run.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Joanne C Masterson
New in #ScienceImmunology:
Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses.
Read more: www.science.org/doi/10.1126/...
Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses.
Read more: www.science.org/doi/10.1126/...
LTβR deficiency causes lymph node aplasia and impaired B cell differentiation
Loss-of-function mutations in LTBR result in a stromal defect, leading to dysfunctional secondary lymphoid organs and combined immunodeficiency in humans.
www.science.org
November 23, 2024 at 8:53 AM
New in #ScienceImmunology:
Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses.
Read more: www.science.org/doi/10.1126/...
Research from @boztugk.bsky.social and team identifies an inborn error of #immunity caused by human LTβR deficiency, resulting in defective stromal cell signaling and impaired humoral immune responses.
Read more: www.science.org/doi/10.1126/...
One of our latest @ JACI
Important role for #HIF driven #metabolic dysfunction in #epithelial differentiation defects in #EoE
Thanks to collaborators @maynoothuni.bsky.social @ StJamesDublin @ChildrensColo @cuanschutz.bsky.social 💶 @researchireland.bsky.social
www.jacionline.org/article/S009...
Important role for #HIF driven #metabolic dysfunction in #epithelial differentiation defects in #EoE
Thanks to collaborators @maynoothuni.bsky.social @ StJamesDublin @ChildrensColo @cuanschutz.bsky.social 💶 @researchireland.bsky.social
www.jacionline.org/article/S009...
November 23, 2024 at 11:44 AM
One of our latest @ JACI
Important role for #HIF driven #metabolic dysfunction in #epithelial differentiation defects in #EoE
Thanks to collaborators @maynoothuni.bsky.social @ StJamesDublin @ChildrensColo @cuanschutz.bsky.social 💶 @researchireland.bsky.social
www.jacionline.org/article/S009...
Important role for #HIF driven #metabolic dysfunction in #epithelial differentiation defects in #EoE
Thanks to collaborators @maynoothuni.bsky.social @ StJamesDublin @ChildrensColo @cuanschutz.bsky.social 💶 @researchireland.bsky.social
www.jacionline.org/article/S009...