Tim Viney
@vineytj.bsky.social
Associate Professor of Neuroscience @ Dept. Pharmacology, University of Oxford.
Spatial memory, cell types, amyloids, dementia, brain rhythms.
https://scholar.google.com/citations?hl=en&user=tgCeCVwAAAAJ&view_op=list_works&sortby=pubdate
Spatial memory, cell types, amyloids, dementia, brain rhythms.
https://scholar.google.com/citations?hl=en&user=tgCeCVwAAAAJ&view_op=list_works&sortby=pubdate
Pinned
***Publication alert***
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
***Publication alert***
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
November 21, 2025 at 11:59 PM
***Publication alert***
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
"Pathological tau alters head direction signaling and induces spatial orientation"
www.cell.com/cell-reports...
Reposting some comments via the Science Media Centre on the UK government's ambition of phasing out animal testing in the UK.
I think it is important for scientists to explain to policymakers and the public about pharmacodynamics and pharmacokinetics - complex interactions between drugs and the body
I think it is important for scientists to explain to policymakers and the public about pharmacodynamics and pharmacokinetics - complex interactions between drugs and the body
expert reaction to Government strategy on animal testing and new alternative methods
www.sciencemediacentre.org/expert-react...
www.sciencemediacentre.org/expert-react...
expert reaction to Government strategy on animal testing and new alternative methods | Science Media Centre
Scientists comment on a new Government strategy on animal testing in the UK. Professor Mary Ryan, Vice Provost for Research and Enterprise at Imperial College London, said: “New technologies are…
www.sciencemediacentre.org
November 11, 2025 at 10:48 PM
Reposting some comments via the Science Media Centre on the UK government's ambition of phasing out animal testing in the UK.
I think it is important for scientists to explain to policymakers and the public about pharmacodynamics and pharmacokinetics - complex interactions between drugs and the body
I think it is important for scientists to explain to policymakers and the public about pharmacodynamics and pharmacokinetics - complex interactions between drugs and the body
Reposted by Tim Viney
This is really interesting. These bacteria form biofilms, which are essentially amyloids
Strep ❤️
Viridans streptococci DNA found in ~42% of coronary plaques, forming biofilms ignored by macrophages
Once fragments escape, TLR2 senses them—potentially triggering an inflammatory response that disrupts plaque stability and increases heart attack risk
www.ahajournals.org/doi/10.1161/...
Viridans streptococci DNA found in ~42% of coronary plaques, forming biofilms ignored by macrophages
Once fragments escape, TLR2 senses them—potentially triggering an inflammatory response that disrupts plaque stability and increases heart attack risk
www.ahajournals.org/doi/10.1161/...
October 24, 2025 at 5:25 PM
This is really interesting. These bacteria form biofilms, which are essentially amyloids
Reposted by Tim Viney
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
A LEAP into the future, or off a cliff: Wellcome LEAP's new $50M program
A few days ago, I saw this post on LinkedIn: How does the gut microbiome shape early brain development? That’s what FORM, a new $50 million...
deevybee.blogspot.com
October 20, 2025 at 1:53 PM
New blogpost on my concerns about Wellcome LEAP new $50m program on autism/microbiome links. deevybee.blogspot.com/2025/10/a-le...
#autism #microbiome #biomarkers #diagnostic
#autism #microbiome #biomarkers #diagnostic
This is a strange and surprising finding. Need to study the electron micrographs in the suppl material carefully (without the colourful shading) to learn more. Note that neurons can have cilia, I wonder if this is what they have detected e.g. recent review here:
doi.org/10.1016/j.tc...
doi.org/10.1016/j.tc...
Nanotubes everywhere between neurons! A bit skeptical about these "dendrite-dendrite nanotubes" from a phalloidin staining in culture, but let's read on… www.science.org/doi/10.1126/...
October 8, 2025 at 8:21 AM
This is a strange and surprising finding. Need to study the electron micrographs in the suppl material carefully (without the colourful shading) to learn more. Note that neurons can have cilia, I wonder if this is what they have detected e.g. recent review here:
doi.org/10.1016/j.tc...
doi.org/10.1016/j.tc...
After many months of work on the revision, we have a paper accepted today (pending minor revisions). Also had a paper rejected at the same time (but going to ignore this email for today!)
October 2, 2025 at 6:51 PM
After many months of work on the revision, we have a paper accepted today (pending minor revisions). Also had a paper rejected at the same time (but going to ignore this email for today!)
Reposted by Tim Viney
Jane Goodall, world-renowned primatologist, dies aged 91
Jane Goodall, world-renowned primatologist, dies aged 91
Jane Goodall Institute says ‘tireless advocate’ for natural world died in California during US speaking tour
The world-renowned primatologist Jane Goodall has died at the age of 91, her institute has said.
The Jane Goodall Institute announced that she had passed away of natural causes while in California as part of a US speaking tour. Continue reading...
www.theguardian.com
October 1, 2025 at 6:35 PM
Jane Goodall, world-renowned primatologist, dies aged 91
Reposted by Tim Viney
What do we know about the causes of #autism? @kingscollegelondon.bsky.social Professor Laura Andreae speaks with BBC Radio 4's Inside Science about the genetic factors behind autism, particularly around twin studies.
🔊 Listen now: www.bbc.co.uk/sounds/play/...
🔊 Listen now: www.bbc.co.uk/sounds/play/...
BBC Inside Science - The science behind autism - BBC Sounds
What do we know about the causes of autism?
www.bbc.co.uk
September 26, 2025 at 10:49 AM
What do we know about the causes of #autism? @kingscollegelondon.bsky.social Professor Laura Andreae speaks with BBC Radio 4's Inside Science about the genetic factors behind autism, particularly around twin studies.
🔊 Listen now: www.bbc.co.uk/sounds/play/...
🔊 Listen now: www.bbc.co.uk/sounds/play/...
This is incredible news!
It is also a good example of why it is so important to identify and define the most vulnerable brain regions and cell types for a given disease. In this case it is medium spiny neurons of the striatum.
It is also a good example of why it is so important to identify and define the most vulnerable brain regions and cell types for a given disease. In this case it is medium spiny neurons of the striatum.
🧵 BREAKING: Gene therapy shows promise in slowing Huntington’s disease progression. A major milestone in neurodegenerative disease research. @uclqsion.bsky.social @ucl-hd.bsky.social
www.bbc.co.uk/news/article...
www.bbc.co.uk/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
www.bbc.co.uk
September 24, 2025 at 6:08 PM
This is incredible news!
It is also a good example of why it is so important to identify and define the most vulnerable brain regions and cell types for a given disease. In this case it is medium spiny neurons of the striatum.
It is also a good example of why it is so important to identify and define the most vulnerable brain regions and cell types for a given disease. In this case it is medium spiny neurons of the striatum.
Reposted by Tim Viney
September 21 is #WorldAlzheimersDay
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
PDB101: Molecule of the Month: Amyloids
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
pdb101.rcsb.org
September 19, 2025 at 4:12 PM
September 21 is #WorldAlzheimersDay
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
Alzheimer's disease and prion diseases are linked to unnatural aggregation of proteins into amyloid fibrils.
Reposted by Tim Viney
🚨New preprint alert!
The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.
Some explanation 🧵👇 1/13
www.biorxiv.org/content/10.1...
The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.
Some explanation 🧵👇 1/13
www.biorxiv.org/content/10.1...
Coherent dynamics of thalamic head-direction neurons irrespective of input
While the thalamus is known to relay and modulate sensory signals to the cortex, whether it also participates in active computation and intrinsic signal generation remains unresolved. The anterodorsal...
www.biorxiv.org
September 16, 2025 at 3:56 PM
🚨New preprint alert!
The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.
Some explanation 🧵👇 1/13
www.biorxiv.org/content/10.1...
The thalamus has long been seen as a relay of sensory signals to cortex.
But could it also generate its own structured activity?
Our study explores this question in the head-direction (HD) system.
Some explanation 🧵👇 1/13
www.biorxiv.org/content/10.1...
*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11
doi.org/10.1101/2025...
🧠📈 🧪
1/11
Granularity of thalamic head direction cells
Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...
doi.org
September 15, 2025 at 3:13 PM
*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11
doi.org/10.1101/2025...
🧠📈 🧪
1/11
Reposted by Tim Viney
15 Sep is the deadline to submit your abstract for a poster or data blitz talk at #iSCAN 2025. Don't miss this opportunity and join us for an exciting meeting on spatial cognition in aging and neurodegeneration!
Abstract submission: tinyurl.com/2r7f8dup
Meeting website: tinyurl.com/mry28bfc
Abstract submission: tinyurl.com/2r7f8dup
Meeting website: tinyurl.com/mry28bfc
August 25, 2025 at 7:28 PM
15 Sep is the deadline to submit your abstract for a poster or data blitz talk at #iSCAN 2025. Don't miss this opportunity and join us for an exciting meeting on spatial cognition in aging and neurodegeneration!
Abstract submission: tinyurl.com/2r7f8dup
Meeting website: tinyurl.com/mry28bfc
Abstract submission: tinyurl.com/2r7f8dup
Meeting website: tinyurl.com/mry28bfc
Reposted by Tim Viney
(buried in a reply, but) This is mind-blowing & deserves a post. Scroll to "video" in this article to watch what happens when the human hypothalamus is stimulated: it's a combo of embarrassment/shame and intense body sensations emanating from the heart. WOW.
www.brainstimjrnl.com/article/S193...
www.brainstimjrnl.com/article/S193...
Complex negative emotions induced by electrical stimulation of the human hypothalamus
Stimulation of the ventromedial hypothalamic region in animals has been reported to
cause attack behavior labeled as sham-rage without offering information about the
internal affective state of the an...
www.brainstimjrnl.com
July 13, 2025 at 8:50 AM
(buried in a reply, but) This is mind-blowing & deserves a post. Scroll to "video" in this article to watch what happens when the human hypothalamus is stimulated: it's a combo of embarrassment/shame and intense body sensations emanating from the heart. WOW.
www.brainstimjrnl.com/article/S193...
www.brainstimjrnl.com/article/S193...
Reposted by Tim Viney
NEW: An Oxford study has found that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk over the following 18 months.
The findings suggest a novel explanation for how vaccines produce this effect.
Read more ⬇️
The findings suggest a novel explanation for how vaccines produce this effect.
Read more ⬇️
How do vaccines reduce the risk of dementia? | University of Oxford
A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in
www.ox.ac.uk
June 26, 2025 at 2:19 PM
NEW: An Oxford study has found that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk over the following 18 months.
The findings suggest a novel explanation for how vaccines produce this effect.
Read more ⬇️
The findings suggest a novel explanation for how vaccines produce this effect.
Read more ⬇️
Reposted by Tim Viney
NEW: Eight exceptional individuals whose achievements have made lasting contributions to the world were recognised today with honorary degrees at Oxford University’s Encaenia.
More information ⬇️
www.ox.ac.uk/news/2025-06...
More information ⬇️
www.ox.ac.uk/news/2025-06...
Honorary degrees awarded at Encaenia 2025 | University of Oxford
Recipients of honorary degrees at Oxford University today included a Nobel laureate and a multiple Olympic, World and European champion, and represented the fields of sport, entertainment,
www.ox.ac.uk
June 25, 2025 at 3:21 PM
NEW: Eight exceptional individuals whose achievements have made lasting contributions to the world were recognised today with honorary degrees at Oxford University’s Encaenia.
More information ⬇️
www.ox.ac.uk/news/2025-06...
More information ⬇️
www.ox.ac.uk/news/2025-06...
Reposted by Tim Viney
Exeter College was honoured to host Lord Crewe’s Benefaction this morning in the Fellows’ Garden, part of @ox.ac.uk Encaenia ceremony.
The Chancellor, Vice-Chancellor, and honorands gathered with other University dignitaries, before processing to the Sheldonian Theatre.
The Chancellor, Vice-Chancellor, and honorands gathered with other University dignitaries, before processing to the Sheldonian Theatre.
June 25, 2025 at 2:29 PM
Exeter College was honoured to host Lord Crewe’s Benefaction this morning in the Fellows’ Garden, part of @ox.ac.uk Encaenia ceremony.
The Chancellor, Vice-Chancellor, and honorands gathered with other University dignitaries, before processing to the Sheldonian Theatre.
The Chancellor, Vice-Chancellor, and honorands gathered with other University dignitaries, before processing to the Sheldonian Theatre.
Reposted by Tim Viney
Whew, what a day!
Today we revealed the preview of NSF–DOE Rubin Observatory's epic cosmic movie🎬 #RubinFirstLook
From wide-field and deep views of the Universe, to the dynamic and changing sky, Rubin is already bringing the night sky to life! 🔭🧪
rubinobservatory.org/news/first-i...
Today we revealed the preview of NSF–DOE Rubin Observatory's epic cosmic movie🎬 #RubinFirstLook
From wide-field and deep views of the Universe, to the dynamic and changing sky, Rubin is already bringing the night sky to life! 🔭🧪
rubinobservatory.org/news/first-i...
Ever-changing Universe Revealed in First Imagery From NSF–DOE Vera C. Rubin Observatory | Rubin Observatory
From distant stars and galaxies to asteroids whizzing through the Solar System, this next-generation facility unveils its first imagery and brings the night sky to life like never before
rubinobservatory.org
June 24, 2025 at 12:43 PM
Whew, what a day!
Today we revealed the preview of NSF–DOE Rubin Observatory's epic cosmic movie🎬 #RubinFirstLook
From wide-field and deep views of the Universe, to the dynamic and changing sky, Rubin is already bringing the night sky to life! 🔭🧪
rubinobservatory.org/news/first-i...
Today we revealed the preview of NSF–DOE Rubin Observatory's epic cosmic movie🎬 #RubinFirstLook
From wide-field and deep views of the Universe, to the dynamic and changing sky, Rubin is already bringing the night sky to life! 🔭🧪
rubinobservatory.org/news/first-i...
Reposted by Tim Viney
If you are in London a week today and are free early evening, please come along to my talk at @royalsociety.org (free!). If you can’t make it, it will be live-streamed and subsequently available online…
The life and times of Francis Crick, or does it matter who does science? | Royal Society
Wilkins-Bernal-Medawar 2024 Prize Lecture delivered by Professor Matthew Cobb
royalsociety.org
June 12, 2025 at 9:37 AM
If you are in London a week today and are free early evening, please come along to my talk at @royalsociety.org (free!). If you can’t make it, it will be live-streamed and subsequently available online…
Reposted by Tim Viney
I've been writing a textbook on computational cognitive neuroscience, which has prompted me to assess the evidence supporting various theoretical ideas. It's striking to me how some ideas have an extraordinary shelf life despite weak evidence.
May 25, 2025 at 11:16 AM
I've been writing a textbook on computational cognitive neuroscience, which has prompted me to assess the evidence supporting various theoretical ideas. It's striking to me how some ideas have an extraordinary shelf life despite weak evidence.
Reposted by Tim Viney
Interesting discussion tonight on How to Hack your Brain to improve learning at Oxford Biohacking Society with my neuroscience colleagues bstaresina.bsky.social and vineytj.bsky.social
May 21, 2025 at 9:43 PM
Interesting discussion tonight on How to Hack your Brain to improve learning at Oxford Biohacking Society with my neuroscience colleagues bstaresina.bsky.social and vineytj.bsky.social
Reposted by Tim Viney
Love seeing the beautiful butterfly at #Tau2025 where 1000+ scientists and clinicians are gathering to share ideas to accelerate biomedical discoveries.
Here is a starter pack to quickly follow TAUrrific researchers. Let me know if I need to add anybody
go.bsky.app/KHno2VG
@millermb.bsky.social
Here is a starter pack to quickly follow TAUrrific researchers. Let me know if I need to add anybody
go.bsky.app/KHno2VG
@millermb.bsky.social
April 24, 2025 at 11:34 AM
Love seeing the beautiful butterfly at #Tau2025 where 1000+ scientists and clinicians are gathering to share ideas to accelerate biomedical discoveries.
Here is a starter pack to quickly follow TAUrrific researchers. Let me know if I need to add anybody
go.bsky.app/KHno2VG
@millermb.bsky.social
Here is a starter pack to quickly follow TAUrrific researchers. Let me know if I need to add anybody
go.bsky.app/KHno2VG
@millermb.bsky.social
Reposted by Tim Viney
Excited to share the sequel to our 2022 paper! In this follow-up, we show that the stable head direction (HD) signals we reported in blind mice rely on stereo olfaction—that is, the comparison of odor info. between the two nostrils.
Link: www.nature.com/articles/s41...
🧵highlights below
Link: www.nature.com/articles/s41...
🧵highlights below
Stereo olfaction underlies stable coding of head direction in blind mice - Nature Communications
Stereo olfaction involves comparing odor differences between the two nostrils. Here, using neuronal recordings and a behavioral test, the authors demonstrate that blind mice use stereo olfaction to fo...
www.nature.com
April 15, 2025 at 6:26 AM
Excited to share the sequel to our 2022 paper! In this follow-up, we show that the stable head direction (HD) signals we reported in blind mice rely on stereo olfaction—that is, the comparison of odor info. between the two nostrils.
Link: www.nature.com/articles/s41...
🧵highlights below
Link: www.nature.com/articles/s41...
🧵highlights below
Reposted by Tim Viney
