Wyoming Wormboy
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wyomingwormboy.bsky.social
Wyoming Wormboy
@wyomingwormboy.bsky.social
Science, students, and service. Serious academic meets incurable class clown.
Reposted by Wyoming Wormboy
🎉 Excited to share our latest preprint📰 !
www.biorxiv.org/cgi/content/...
Many thanks to everyone involved in this project ! Using a zebrafish model 🐟 and iPSC-derived motor neurons 🔬 we show that restoring the calpastatin/calpain pathway preserves motoneuron survival and function in C9orf72 ALS!
Therapeutic modulation of the calpastatin/calpain pathway restores calpain-mediated synaptic proteolysis and preserves motor neurons survival and function in C9orf72 ALS
A hexanucleotide repeat expansion (GGGGCC) in the C9orf72 gene is the most prevalent genetic cause of ALS, with early neuromuscular junction (NMJ) dysfunction being a key pathological feature. Current...
www.biorxiv.org
December 12, 2025 at 3:21 PM
Reposted by Wyoming Wormboy
Deadline for this post-doc position in my lab extended to Jan 11th!
I'm looking to recruit a post-doc to help push forward our growing interests in insect ecotoxicology.
Apply here by Nov 30th!
(thanks for reposting)

career5.successfactors.eu/sfcareer/job...
Career Opportunities: Posdoctoral researcher in toxin susceptibility and evolution of resistance in insects (22517)
career5.successfactors.eu
December 12, 2025 at 3:01 PM
Hot off the press at EMBO Journal. The culmination of several years of work and hopefully useful to people in the field!

BIG Shout-out to Review Commons, who handled the submission. It's a sensible and efficient model and all the journals I like (Society and NFP) are already participating. 🙏
Integrating endogenous TurboID and data-independent acquisition mass spectrometry for in vivo proximity labeling - The EMBO Journal
Proximity labeling has emerged as a powerful approach for identifying protein–protein interaction networks within living systems, particularly those involving weak or transient associations. Here, we ...
link.springer.com
December 11, 2025 at 11:04 PM
December 11, 2025 at 7:41 PM
December 11, 2025 at 7:40 PM
December 11, 2025 at 7:39 PM
December 11, 2025 at 7:38 PM
December 11, 2025 at 7:38 PM
If plants could grow on Mars…
December 9, 2025 at 7:23 AM
The amazing silversword plant
December 9, 2025 at 7:22 AM
Crater at sunset
December 9, 2025 at 7:19 AM
Crater from the south.
December 9, 2025 at 5:56 AM
Haleakala crater from the north side.
December 9, 2025 at 5:53 AM
December 8, 2025 at 3:50 AM
Coffee shop
December 7, 2025 at 6:37 PM
Oh man, what a race! Last year of racing for the best cross country skier in the history of North America.
December 7, 2025 at 8:13 AM
Where am I?
December 6, 2025 at 5:11 AM
Reposted by Wyoming Wormboy
Huge congratulations to Minnesota’s own Jessie Diggins on an incredible career as she retires from competitive cross-country skiing! An Olympic gold medalist, you made us all proud. We can’t wait to cheer you on in 76 days!

www.mprnews.org/story/2025/1...
Minnesotan Jessie Diggins announces upcoming retirement from ski racing
Diggins has won three Olympic medals, three World Cup titles and seven world championship medals in her career — most of which the 34-year-old won while competing with glitter on her cheeks.
www.mprnews.org
November 22, 2025 at 10:38 PM
Reposted by Wyoming Wormboy
"What we see on the street is just the tip of the iceberg. There's an entire world of homelessness that has been rendered invisible."

Here's the YouTube link to my PBS News Weekend interview:
Millions of full-time workers are struggling to afford a place to live. Here’s why
YouTube video by PBS NewsHour
www.youtube.com
November 30, 2025 at 12:04 AM
Waiting for snow to cover our trails. Late start to the ski season in the west.
November 30, 2025 at 2:30 AM
Reposted by Wyoming Wormboy
Worm people are the best
November 28, 2025 at 1:15 PM
From The Onion’s brilliant editorial cartoonist. Unquestionably the most accurate depiction of a generic research scientist ever rendered.
November 23, 2025 at 7:25 PM
Wyoming
November 22, 2025 at 11:00 PM