Yolanda Perez
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yolandapereznmr.bsky.social
Yolanda Perez
@yolandapereznmr.bsky.social
Senior researcher Biotransformations's 🧫 Group and 🧲 NMR Core Lead at IQAC-CSIC🔸Interested in IDPs and metalloenzymes from a structural viewpoint #NMRchat🔹 Barcelona (Spain)
🔗 www.linkedin.com/in/yolanda-perez-4797ba290
📖 ORCID: 0000-0003-3767-5346
Pinned
EMBO postdoc fellowship application deadline coming up!

Our research group has started a new line of research that integrates structural biology approaches—particularly NMR—to elucidate enzyme structure–function relationships and develop innovative biocatalysts for biotechnological applications.
Reposted by Yolanda Perez
Let me tell you a story. Perhaps you can guess where this is going... though it does have a bit of a twist.

I was poking around Google Scholar for publications about the relationship between chatbots and wellness. Oh how useful: a systematic literature review! Let's dig into the findings. 🧵
December 5, 2025 at 10:35 PM
Reposted by Yolanda Perez
I just published: ERC-Plus: jackpot science or missed chance to fix academia?

My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re building.

medium.com/p/erc-plus-j...
ERC-Plus: jackpot science or missed chance to fix academia?
My reflections on ERC-Plus, Europe’s newest ultra-competitive research grant and what it tells us about the academic culture we’re…
medium.com
December 3, 2025 at 11:42 AM
Reposted by Yolanda Perez
🌊 Serendipity often drives science forward.

A “lost” Argo float drifted under Antarctica’s ice shelves and resurfaced with a warning: warm water is creeping under major glaciers like Denman and Totten.

What’s at risk? Up to 5 m of global sea-level rise.

theconversation.com/what-our-mis...
What our missing ocean float revealed about Antartica’s melting glaciers
Our ocean float spent years adrift in the Antarctic ocean and beneath massive ice shelves. What it found will help us estimate global sea-level rise.
theconversation.com
December 6, 2025 at 5:56 AM
Reposted by Yolanda Perez
The limitations of 19F GARP decoupling and why you should be careful on how you interpret your NMR line shapes and coupling patterns. u-of-o-nmr-facility.blogspot.com/2018/06/the-... #nmr #nmrchat #chemsky
December 4, 2025 at 9:17 AM
Reposted by Yolanda Perez
Reposted by Yolanda Perez
December 4, 2025 at 5:30 PM
EMBO postdoc fellowship application deadline coming up!

Our research group has started a new line of research that integrates structural biology approaches—particularly NMR—to elucidate enzyme structure–function relationships and develop innovative biocatalysts for biotechnological applications.
December 3, 2025 at 5:57 PM
Reposted by Yolanda Perez
Join us for our upcoming webinar next week, where we will trace the journey of protein data from the lab bench and scientific literature into the UniProt Knowledgebase.

Registration is free but essential:
www.ebi.ac.uk/training/eve...

🖥️🧬
December 2, 2025 at 10:51 AM
Reposted by Yolanda Perez
CNRS cancels Web of Science in order to focus on qualitative evaluation and promoting the development of open databases.

www.cnrs.fr/en/update/cn...
The CNRS is breaking free from the Web of Science
From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'
www.cnrs.fr
December 1, 2025 at 12:31 PM
Reposted by Yolanda Perez
The most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.
November 30, 2025 at 8:00 PM
Reposted by Yolanda Perez
Integrative In Silico and In Vitro Screening of Low Molecular Weight Compounds Targeting SARS‐CoV‐2 RNA Elements - Toews - ChemBioChem - Wiley Online Library chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
Integrative In Silico and In Vitro Screening of Low Molecular Weight Compounds Targeting SARS‐CoV‐2 RNA Elements
A combined virtual and nuclear magnetic resonance (NMR)-based screening approach identifies small molecules that bind conserved SARS-CoV-2 RNA structures. Diverse compound libraries are screened usin....
chemistry-europe.onlinelibrary.wiley.com
November 30, 2025 at 8:29 AM
Reposted by Yolanda Perez
I believe that we are about to see a major scientific conflict play out here on BlueSky, for better or for worse. I'll weigh in on this on the blog once I'm sure that I understand everyone's positions:
November 29, 2025 at 5:41 PM
Reposted by Yolanda Perez
Let’s run the numbers on this new @ERC_Research “ERC-Plus” scheme. About 30 grants to be awarded, and we’re told “better apply for a regular grant, your chances are 30× higher.”

www.researchprofessionalnews.com/rr-news-euro...
ERC’s new €7m Plus Grants open to researchers at any career stage - Research Professional News
European Research Council president describes scheme as part attempt to lure US talent
www.researchprofessionalnews.com
November 30, 2025 at 10:20 AM
Reposted by Yolanda Perez
First crystal structure of a metalloprotein at 120 °C shows changes in H-bonding compared to cryogenic crystal structures. Exciting work from Cramer et al., out now with @angewandtechemie.bsky.social
doi.org/10.1002/anie...
November 29, 2025 at 11:39 AM
Reposted by Yolanda Perez
Your periodic reminder that science is not done by a few selected "stars scientists". Science is done by hundred of thousands. Siloed money mean a few flashy discoveries and a lot of waste. Want to change things? Make funding accessible and stop funding calls with less than 2% success rate.
· #AcademicSky ·
The European Research Council is launching €7m Plus Grants for ambitious, long‑term research — open to researchers at any career stage but limited to about 30 awards; current ERC grantees and applicants are ineligible, reports @clanicholson.bsky.social.
ERC’s new €7m Plus Grants open to researchers at any career stage - Research Professional News
European Research Council president describes scheme as part attempt to lure US talent
www.researchprofessionalnews.com
November 29, 2025 at 10:53 AM
Reposted by Yolanda Perez
@angewandtechemie.bsky.social (open) Ultrabroadband 1D and 2D NMR Spectroscopy, corresponding Burkhard Luy @kit.edu Dedicated to Richard R. Ernst (1933–2021) onlinelibrary.wiley.com/doi/10.1002/... #NMRchat #NMR 🧲
Ultrabroadband 1D and 2D NMR Spectroscopy
Optimal control-derived saturation pulses allow 1D and 2D NMR spectroscopy covering spectral ranges in the MHz range. Next to a multitude of nuclei even multinuclear spectra are possible.
onlinelibrary.wiley.com
November 28, 2025 at 1:33 PM
Reposted by Yolanda Perez
Please check out our just published article
www.nature.com/articles/s41...
, in which we demonstrate a proof-of-principle example of an NH-pi #hydrogen_bond on the surface of an IDP through detection of an ultra-weak J coupling by #NMR, supported by #MD and #DFT.
Direct detection of an NH-π hydrogen bond in an intrinsically disordered peptide - Nature Communications
The authors demonstrate a proof-of-principle example of an NH-π hydrogen bond on the surface of an intrinsically disordered protein through detection of weak scalar couplings by NMR, supported by Mole...
www.nature.com
November 27, 2025 at 9:24 PM
Reposted by Yolanda Perez
Tomorrow, Friday, November 28, noon CET / 6 am EST, Konstantin Ivanov Intercontinental Magnetic Resonance Seminar, François-Xavier Theillet, CITCoM, Université Paris Cité, France, In-cell structural biology using NMR: overview and latest developments sites.google.com/view/nmr-sem... #NMRchat #NMR 🧲
ICONS Series
Konstantin Ivanov intercontinental magnetic resonance seminar series started on April 8, 2020. It organises seminars on a range of topics in magnetic resonance covering NMR, EPR, hyperpolarisation, co...
sites.google.com
November 27, 2025 at 6:59 PM
Reposted by Yolanda Perez
We show structural details of TDP-43's C-terminal helix assembly into functional multimers, explaining dysfunction caused by several disease mutations (in Nature Comm). Appropriate for Thanksgiving day, there is a critical tryptophan! with @mittalgrouptamu.bsky.social
www.nature.com/articles/s41...
Structural details of helix-mediated multimerization of the conserved region of TDP-43 C-terminal domain - Nature Communications
RNA-binding protein TDP-43 contains a region forming a dynamic α-helical multimer that accounts for its functional role, evolutionary conservation, and disruption in amyotrophic lateral sclerosis, mak...
www.nature.com
November 27, 2025 at 7:13 PM
Reposted by Yolanda Perez
Proteins are dynamic structures, but structural biology often shows them as static snapshots. Inspired by long-exposure photography and generative art, I built ProteinCHAOS, an artistic tool inspired by molecular dynamics to capture protein flexibility over time, much like long-exposure images.
November 23, 2025 at 11:18 PM
Reposted by Yolanda Perez
Take a look through the Instruct-ERIC Facility starter pack!

Find the technology and expertise in structural biology that you need, and receive funded access to any of these facilities through Instruct - bsky.app/starter-pack...
November 24, 2025 at 9:27 AM
Reposted by Yolanda Perez
Reposted by Yolanda Perez
Oops. Ooooooooooooops.

I do hope that nobody has been given or denied a job/promotion based on their SpringerNature citation counts in the past 15 years.

arxiv.org/pdf/2511.01675

h/t @nathlarigaldie.bsky.social
November 7, 2025 at 2:02 PM