From January 1st 2026, the CNRS will cut access to one of the largest commercial bibliometric databases, Clarivate Analytics'

A combined virtual and nuclear magnetic resonance (NMR)-based screening approach identifies small molecules that bind conserved SARS-CoV-2 RNA structures. Diverse compound libraries are screened usin....

European Research Council president describes scheme as part attempt to lure US talent

Optimal control-derived saturation pulses allow 1D and 2D NMR spectroscopy covering spectral ranges in the MHz range. Next to a multitude of nuclei even multinuclear spectra are possible.

The authors demonstrate a proof-of-principle example of an NH-π hydrogen bond on the surface of an intrinsically disordered protein through detection of weak scalar couplings by NMR, supported by Mole...

Konstantin Ivanov intercontinental magnetic resonance seminar series started on April 8, 2020. It organises seminars on a range of topics in magnetic resonance covering NMR, EPR, hyperpolarisation, co...

RNA-binding protein TDP-43 contains a region forming a dynamic α-helical multimer that accounts for its functional role, evolutionary conservation, and disruption in amyotrophic lateral sclerosis, mak...

Communications Chemistry, Published online: 26 November 2025; doi:10.1038/s42004-025-01763-0Although many proteins function by toggling between distinct conformations, most structure predictors remain limited to a single static fold. Here, the authors test the performance of AlphaFold2, AlphaFold3, and recent variants on a dataset of autoinhibited proteins exhibiting at least two functionally distinct conformations, and show that AlphaFold2 fails to reproduce the experimental structures of many autoinhibited proteins, but that it can capture conformational diversity when using uniform multiple sequence alignment subsampling.

La investigación, como tópico de entretenimiento, siempre es una buena inversión para periódicos, películas e informativos de radio y televisión: toca temas curiosos o sensibles, luce tecnología, fome...

Collective experiment found switching profile to ‘male’ and ‘bro-coding’ text led to big increase in reach, though site denies favouring posts by men

Though they live only a few hours before dividing, bacteria can anticipate the approach of cold weather and prepare for it. The discovery suggests that seasonal tracking is fundamental to life.