Zheng Shi
@zs-biophys.bsky.social
Assistant Professor at Rutgers Chemistry and Chemical Biology, studies cell membranes and biomolecular condensates.
https://sites.rutgers.edu/shi-lab/
https://sites.rutgers.edu/shi-lab/
Pinned
Zheng Shi
@zs-biophys.bsky.social
Β· May 29
Looking for a postdoc - Shi Lab
The Shi lab at Rutgers-New Brunswick is seeking a postdoctoral researcher to study biomolecular condensates and/or mechanosensitive membrane proteins. To see more information and apply, please go toΒ t...
sites.rutgers.edu
We are looking for a postdoc to study biomolecular condensates and/or mechanosensitive membrane proteins. Please help spread the news π
sites.rutgers.edu/shi-lab/look...
sites.rutgers.edu/shi-lab/look...
Reposted by Zheng Shi
What's the relation between voltage and calcium in dendrites? Xiang Wu studied this in CA2 hippocampal pyramidal cells in behaving mice. www.biorxiv.org/content/10.6...
January 21, 2026 at 7:51 PM
What's the relation between voltage and calcium in dendrites? Xiang Wu studied this in CA2 hippocampal pyramidal cells in behaving mice. www.biorxiv.org/content/10.6...
looks more expensive than ours π
January 16, 2026 at 3:34 AM
looks more expensive than ours π
People in the lab made me this βΊοΈ
January 16, 2026 at 1:41 AM
People in the lab made me this βΊοΈ
Reposted by Zheng Shi
Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! π§ͺ
January 5, 2026 at 2:48 PM
Happy new year! I've so enjoyed the end-of-year lists of people's favorite papers from 2025, so I made a list of 16 #lipidtime studies from 2025 that I found interesting. Here they are in no particular order (please add more if you would like!), and here's to much more exciting science in 2026! π§ͺ
Reposted by Zheng Shi
What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
January 4, 2026 at 6:17 AM
What is the computational role of dendritic excitations? Byung Hun Lee and team mapped voltage dynamics throughout the dendritic trees of CA1 pyramidal neurons in mice navigating in virtual reality. www.biorxiv.org/content/10.6...
Reposted by Zheng Shi
If you're at #cellbio2025, @atmolines.bsky.social Hernan Garcia and I invite you to attend our Minisymposium βPhysical Cell Biology from Molecules to Organismsβ for incredible talks on epigenetic mechanical memory, viscoelasticity, cortical flows, morphogenesis, tissue wetting, size scaling, et al!
December 5, 2025 at 11:13 PM
If you're at #cellbio2025, @atmolines.bsky.social Hernan Garcia and I invite you to attend our Minisymposium βPhysical Cell Biology from Molecules to Organismsβ for incredible talks on epigenetic mechanical memory, viscoelasticity, cortical flows, morphogenesis, tissue wetting, size scaling, et al!
Reposted by Zheng Shi
Membrane potential s an important regulator of cell number density and growth via Hippo-FAT1 signaling in response to mechanical pressure
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @harvardmed.bsky.social
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @harvardmed.bsky.social
December 2, 2025 at 8:04 PM
Membrane potential s an important regulator of cell number density and growth via Hippo-FAT1 signaling in response to mechanical pressure
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @harvardmed.bsky.social
www.cell.com/cell/fulltex... @cellcellpress.bsky.social @harvardmed.bsky.social
Reposted by Zheng Shi
An idea we started in 2019 is now published in @natneuro.nature.com! Excited to share our new study: rdcu.be/eRvdA
Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
November 24, 2025 at 2:17 PM
An idea we started in 2019 is now published in @natneuro.nature.com! Excited to share our new study: rdcu.be/eRvdA
Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
Congrats to Mengmeng Jin and our team! Heartfelt thanks to all collaborators for their support, and to the reviewers for their insightful comments!
... and we should be careful when comparing surface objects to 3-dimentional ones. Things can get very confusing!
October 31, 2025 at 8:17 PM
... and we should be careful when comparing surface objects to 3-dimentional ones. Things can get very confusing!
... I put the dot there, because it fits nicely to a corner of the Central Park!
In other words, fresh water in lakes and rivers corresponds to the volume of more than 1,000,000 billion human!
So, yes, fresh water is a valuable resource - but, might not be as scarce as shown in the first image...
In other words, fresh water in lakes and rivers corresponds to the volume of more than 1,000,000 billion human!
So, yes, fresh water is a valuable resource - but, might not be as scarce as shown in the first image...
October 31, 2025 at 8:17 PM
... I put the dot there, because it fits nicely to a corner of the Central Park!
In other words, fresh water in lakes and rivers corresponds to the volume of more than 1,000,000 billion human!
So, yes, fresh water is a valuable resource - but, might not be as scarce as shown in the first image...
In other words, fresh water in lakes and rivers corresponds to the volume of more than 1,000,000 billion human!
So, yes, fresh water is a valuable resource - but, might not be as scarce as shown in the first image...
.. But, how does '8 billion people' fit on this image?
It was already shown.
Did you notice it?
If not, let me help you with this red arrow.
It turns out, 8 billion people can 'nicely' pack into a sphere of 1 km diameter.
In this image, it's represented by that tiny red dot in New York City...
It was already shown.
Did you notice it?
If not, let me help you with this red arrow.
It turns out, 8 billion people can 'nicely' pack into a sphere of 1 km diameter.
In this image, it's represented by that tiny red dot in New York City...
October 31, 2025 at 8:17 PM
.. But, how does '8 billion people' fit on this image?
It was already shown.
Did you notice it?
If not, let me help you with this red arrow.
It turns out, 8 billion people can 'nicely' pack into a sphere of 1 km diameter.
In this image, it's represented by that tiny red dot in New York City...
It was already shown.
Did you notice it?
If not, let me help you with this red arrow.
It turns out, 8 billion people can 'nicely' pack into a sphere of 1 km diameter.
In this image, it's represented by that tiny red dot in New York City...
... Let me show this on a different map. The map of New Jersey, one of the smallest states in the US.
The entirety of fresh water barely covers NJ, and fresh water in lakes/rivers barely fills a small county.
These are supposed to support the need of ~8 Billion people, isn't that crazy?! ...
The entirety of fresh water barely covers NJ, and fresh water in lakes/rivers barely fills a small county.
These are supposed to support the need of ~8 Billion people, isn't that crazy?! ...
October 31, 2025 at 8:17 PM
... Let me show this on a different map. The map of New Jersey, one of the smallest states in the US.
The entirety of fresh water barely covers NJ, and fresh water in lakes/rivers barely fills a small county.
These are supposed to support the need of ~8 Billion people, isn't that crazy?! ...
The entirety of fresh water barely covers NJ, and fresh water in lakes/rivers barely fills a small county.
These are supposed to support the need of ~8 Billion people, isn't that crazy?! ...
... leaving only that tiny blue pixel (representing fresh water in lakes and rivers) readily available to us.
When I first saw this picture in school, I was so impressed. I was convinced that fresh water is an extremely limited resource for humanity. Yet, something always felt counterintuitive...
When I first saw this picture in school, I was so impressed. I was convinced that fresh water is an extremely limited resource for humanity. Yet, something always felt counterintuitive...
October 31, 2025 at 8:17 PM
... leaving only that tiny blue pixel (representing fresh water in lakes and rivers) readily available to us.
When I first saw this picture in school, I was so impressed. I was convinced that fresh water is an extremely limited resource for humanity. Yet, something always felt counterintuitive...
When I first saw this picture in school, I was so impressed. I was convinced that fresh water is an extremely limited resource for humanity. Yet, something always felt counterintuitive...
In the spirit of Halloween, let me share with you a 'scary' piece of statistics.
Many of you may have seen this image, which demonstrates the extreme scarcity of fresh water on Earth.
That small droplet over Atlanta is our ENTIRE storage of fresh water. But, most of those are hard to get...
Many of you may have seen this image, which demonstrates the extreme scarcity of fresh water on Earth.
That small droplet over Atlanta is our ENTIRE storage of fresh water. But, most of those are hard to get...
October 31, 2025 at 8:17 PM
In the spirit of Halloween, let me share with you a 'scary' piece of statistics.
Many of you may have seen this image, which demonstrates the extreme scarcity of fresh water on Earth.
That small droplet over Atlanta is our ENTIRE storage of fresh water. But, most of those are hard to get...
Many of you may have seen this image, which demonstrates the extreme scarcity of fresh water on Earth.
That small droplet over Atlanta is our ENTIRE storage of fresh water. But, most of those are hard to get...
Reposted by Zheng Shi
Happy to share that this work is now published in @biophysj.bsky.social! doi.org/10.1016/j.bp...
In developing embryos, cells move a lot! Plenty of that movement is random. Is random cell mixing a feature or bug for tissue patterning? Turns out, itβs both! Excited to share the 1st preprint from my postdoc w/ Sean Megason @seanemcgeary.bsky.social and Allon Klein. 1/20 doi.org/10.1101/2025...
October 23, 2025 at 4:30 PM
Happy to share that this work is now published in @biophysj.bsky.social! doi.org/10.1016/j.bp...
Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells | Science Advances www.science.org/doi/10.1126/...
Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells
MINFLUX nanoscopy reveals subcellular distribution and conformational diversity of PIEZO1 channels in intact cells.
www.science.org
October 23, 2025 at 1:23 PM
Cluster nanoarchitecture and structural diversity of PIEZO1 at rest and during activation in intact cells | Science Advances www.science.org/doi/10.1126/...
Apparently, these are the main (research) topics we are known for within my university :)
Fun fact: if you google "Rutgers tension", we are among the top hits - only behind the 2023 Rutgers University strike...
Fun fact: if you google "Rutgers tension", we are among the top hits - only behind the 2023 Rutgers University strike...
October 22, 2025 at 7:50 PM
Apparently, these are the main (research) topics we are known for within my university :)
Fun fact: if you google "Rutgers tension", we are among the top hits - only behind the 2023 Rutgers University strike...
Fun fact: if you google "Rutgers tension", we are among the top hits - only behind the 2023 Rutgers University strike...
I never truly appreciated the name Invitrogen until I came across a company called 'Invivogen'.
October 16, 2025 at 10:33 PM
I never truly appreciated the name Invitrogen until I came across a company called 'Invivogen'.
Mechanical Regulation And Activity of Nuclear Condensates: Biophysical Journal www.cell.com/biophysj/ful...
Mechanical Regulation And Activity of Nuclear Condensates
The cell nucleus is constantly subjected to forces under many fundamental biological
processes, including confined cell migration, osmoregulation, and large-scale stresses
across tissues during develo...
www.cell.com
October 10, 2025 at 1:32 PM
Mechanical Regulation And Activity of Nuclear Condensates: Biophysical Journal www.cell.com/biophysj/ful...
Congratulations to the βReal Chemistβπ¨βπ¬
October 8, 2025 at 9:38 PM
Congratulations to the βReal Chemistβπ¨βπ¬
Reposted by Zheng Shi
πThe #BiomembraneDays2025 concluded
WE THANK ALL PARTICIPANTS & OUR SPONSORSπππ
@abberior.rocks
Critical Insights in Biophysics
Ernst Rudolf SchloeΓmann Foundation
@dfg.de
@jcellsci.bsky.social
@lipotype.bsky.social
@naniontech.bsky.social
@picoquant.bsky.social
Refeyn Ltd
@biologists.bsky.social
WE THANK ALL PARTICIPANTS & OUR SPONSORSπππ
@abberior.rocks
Critical Insights in Biophysics
Ernst Rudolf SchloeΓmann Foundation
@dfg.de
@jcellsci.bsky.social
@lipotype.bsky.social
@naniontech.bsky.social
@picoquant.bsky.social
Refeyn Ltd
@biologists.bsky.social
October 4, 2025 at 4:29 PM
πThe #BiomembraneDays2025 concluded
WE THANK ALL PARTICIPANTS & OUR SPONSORSπππ
@abberior.rocks
Critical Insights in Biophysics
Ernst Rudolf SchloeΓmann Foundation
@dfg.de
@jcellsci.bsky.social
@lipotype.bsky.social
@naniontech.bsky.social
@picoquant.bsky.social
Refeyn Ltd
@biologists.bsky.social
WE THANK ALL PARTICIPANTS & OUR SPONSORSπππ
@abberior.rocks
Critical Insights in Biophysics
Ernst Rudolf SchloeΓmann Foundation
@dfg.de
@jcellsci.bsky.social
@lipotype.bsky.social
@naniontech.bsky.social
@picoquant.bsky.social
Refeyn Ltd
@biologists.bsky.social
Thatβs great, thanks Helge!
October 4, 2025 at 5:46 AM
Thatβs great, thanks Helge!
Canβt believe Germany π©πͺ has an entire day off so that people can listen to the new Taylor Swift album π§πΆ π
Any lab here open to hosting a visiting scientist next year?
For someone who is interested in advanced microscopy and cellular mechanics (and can still do experiments π)?
Any lab here open to hosting a visiting scientist next year?
For someone who is interested in advanced microscopy and cellular mechanics (and can still do experiments π)?
October 3, 2025 at 9:15 PM
Canβt believe Germany π©πͺ has an entire day off so that people can listen to the new Taylor Swift album π§πΆ π
Any lab here open to hosting a visiting scientist next year?
For someone who is interested in advanced microscopy and cellular mechanics (and can still do experiments π)?
Any lab here open to hosting a visiting scientist next year?
For someone who is interested in advanced microscopy and cellular mechanics (and can still do experiments π)?