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Jesse Shapiro

@bjesseshapiro.bsky.social

1.7K followers 710 following 400 posts

Macrobe qui aime les microbes http://www.shapirolab.ca/

Jesse M. Shapiro is an American economist who has served as the George Gund Professor of Economics and Business Administration at Harvard University since 2022. He was previously the George S. and Nancy B. Parker Professor of Economics at Brown University from 2015 to 2019, and the Eastman Professor of Political Economy at Brown from 2019 to 2021. He received a MacArthur Fellowship in 2021. .. more

Economics 40%

Political science 16%

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Jesse Shapiro @bjesseshapiro.bsky.social · Jul 1

One of my favourite serendipitous results from the lab came about because we were long-read sequencing bacterial:

Vibrio cholerae, which is "supposed to" have TWO circular chromosomes (3 + 1 million base pairs) often has just ONE fused chromosome (4 Mbp).

www.nature.com/articles/s41...

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Prevalent chromosome fusion in Vibrio cholerae O1 - Nature Communications

The pathogenic bacterium Vibrio cholerae typically has two circular chromosomes. Here, Cuénod et al. analyse 467 clinical isolates and identify several independent chromosome fusion events that are li...

www.nature.com

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Reposted by Ben C. Sheldon, Jesse M. Shapiro, Elena Litchman

Michael Brockhurst @brockhurstlab.bsky.social · 8h

Three Bicentenary research fellowships on offer at @officialuom.bsky.social @fbmh-uom.bsky.social for exceptional ECRs with <3y postdoc experience

3yrs salary + £30k pa research expenses

Do you have a great idea & want to join @mermanchester.bsky.social?

www.bmh.manchester.ac.uk/research/sup...

Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester

Find out about and apply for a Bicentenary Early Career Research Fellowship.

www.bmh.manchester.ac.uk

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Jesse Shapiro @bjesseshapiro.bsky.social · 10h

Reading the acknowledgments section of my student's PhD thesis...

a man in a blue jacket is crying and says " are you crying "

ALT: a man in a blue jacket is crying and says " are you crying "

media.tenor.com

Reposted by Jesse M. Shapiro

Joshua Weitz @joshuasweitz.bsky.social · 17h

Meanwhile in Canada, there have been more reported measles cases in Alberta (cases: 1,923; population: ~5M) than reported in all of the US this year (cases: 1,563, population: ~340M).

Consequence: "The Americas region is at risk of losing its measles-free status..."

globalnews.ca/news/1146683...

Measles, Canada... 1,923 cases total

https://www.alberta.ca/measles

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Reposted by Jesse M. Shapiro

Craig MacLean @craigmaclean.bsky.social · 19h

New pre-print www.biorxiv.org/content/10.1...
Plasmid-dependent phage (PDPs) are ubiquitous, but the selective pressures that they impose on plasmids are not well understood. Project led by Daniel Cazares in collaboration with @brockhurstlab.bsky.social!
#phagesky#microsky

Trade-offs between phage resistance and conjugative ability shape the ecological and evolutionary response of a multidrug resistance plasmid to plasmid-dependent phage

Phage therapy is a promising alternative to antibiotics to treat multidrug resistant infections. Plasmid dependent phages (PDPs) are particularly attractive as therapeutics because they can both kill ...

www.biorxiv.org

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Jesse Shapiro @bjesseshapiro.bsky.social · 1d

Bon conseil ;)

Jesse Shapiro @bjesseshapiro.bsky.social · 1d

Would love to. Let’s keep in touch.

Jesse Shapiro @bjesseshapiro.bsky.social · 2d

Around Montpellier! Exact location TBA, depends on the quality of local bike routes ;)

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Jesse Shapiro @bjesseshapiro.bsky.social · 2d

Fall 2026 to summer 2027! Want to come visit? Will you be nearby?

Jesse Shapiro @bjesseshapiro.bsky.social · 2d

Sabbatical planning: step 1.

A photo of a cycling map of France on a table beside a glass of beer on a table in a bar.

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Reposted by Jesse M. Shapiro

John Dennehy @drjdennehy.bsky.social · 2d

www.cell.com/trends/ecolo...

New entry into the Disability in Ecology and Evolution series in TREE featuring me :)

Disability in ecology and evolution

In this TrendsTalk series 'Disability in ecology and evolution' in Trends in Ecology and Evolution, we will be hearing from people about their experiences being disabled in ecology and evolution. We a...

www.cell.com

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Reposted by Jesse M. Shapiro, Danny Dorling, Juan Rocha

Julie Talbot @julietalbot.bsky.social · 3d

My department @geographieudem.bsky.social is looking for a professor in human geography specializing in the study of social-ecological transformations, political ecology, climate change, environmental justice and/or the geography of risks and infrastructures. Deadline November 10, share widely!

Glass buildings with a paved path in between (gray, with blue lines)

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Reposted by Jesse M. Shapiro

Dave Baltrus 🦦 @surtlab.bsky.social · 3d

Here’s published version of our manuscript using GWAS to investigate tailocin sensitivity in Pseudomonas syringae. TL:DR pretty clear LPS is tailocin receptor but also that P.syringae often completely swaps out its entire O antigen biosynth pathway w/ recombination

academic.oup.com/g3journal/ad...

Genomic correlates of tailocin sensitivity in Pseudomonas syringae

Abstract. Phage-derived bacteriocins, also referred to as tailocins, are structures encoded by bacterial genomes and deployed into the extracellular enviro

academic.oup.com

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Reposted by Jesse M. Shapiro, Simon Roux, José R. Penadés , and 1 more Jesse M. Shapiro, Simon Roux, José R. Penadés, Alan McNally

Michael Brockhurst @brockhurstlab.bsky.social · 3d

New preprint!

Ever wondered why only a fraction of genomes encode CRISPR immunity? 🧬 🦠

Turns out CRISPR is rarely beneficial against virulent phages, being most beneficial against those for which resistance mutations are rare!

An epic effort by Rosanna Wright

www.biorxiv.org/content/10.1...

Resistance mutation supply modulates the benefit of CRISPR immunity against virulent phages

Only a fraction of bacterial genomes encode CRISPR-Cas systems but the selective causes of this variation are unexplained. How naturally virulent bacteriophages (phages) select for CRISPR immunity has...

www.biorxiv.org

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Reposted by Jesse M. Shapiro

Ákos T Kovács @evolvedbiofilm.bsky.social · 6d

Filamentous cheater phages drive bacterial and phage populations to lower fitness

Pseudomonas aeruginosa VS Pf phage

@currentbiology.bsky.social by @nanamikubota.bsky.social, @shellyscrib.bsky.social and @vscooper.micropopbio.org

www.cell.com/current-biol...

#PhageSky

Filamentous cheater phages drive bacterial and phage populations to lower fitness

Kubota et al. show that bacteria can use their filamentous phage to outcompete other bacteria, but increased phage production enables the evolution of cheater miniphages with truncated genomes. Miniph...

www.cell.com

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Reposted by Jesse M. Shapiro

Current Biology @currentbiology.bsky.social · 8d

Sad news: Jane Goodall has died. She did more than any other human for our understanding and appreciation of our closest relatives, the chimpanzees.

That chimpanzees are Endangered tells you everything about our species and about what made her so exceptional.

www.nytimes.com/2025/10/01/o...

Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91

www.nytimes.com

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Jesse Shapiro @bjesseshapiro.bsky.social · 9d

Hello October!

A corner grocery store with a plethora of pumpkins spilling out on the sidewalk, draped with fake cobwebs and other Halloween decorations.

Reposted by Jesse M. Shapiro

McGill Centre for Microbiome Research @mcgill-microbiome.bsky.social · 9d

The McGill Centre for Microbiome Research is hosting a mini-symposium Oct 21! Microbiome and Pain: Unraveling the Gut-Brain connection. Sign up for a great morning of student talks, networking and a keynote from Dr. David Bulmer! www.eventbrite.ca/e/microbiome...

Microbiome and Pain: Unraveling the Gut-Brain connection

Join us for this co-hosted half-day seminar with the Alan Edwards Centre for Research on Pain. Keynote speaker: Dr David Bulmer.

www.eventbrite.ca

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Reposted by Jesse M. Shapiro, José R. Penadés

Craig MacLean @craigmaclean.bsky.social · 9d

New pre-print
Competition between phage constrains adaptation to thermal fluctuating temperatures.
More work led by Sam Greenrod in collaboration with @kayla-king.bsky.social lab.
#Phagesky#Microsky

www.biorxiv.org/content/10.1...

www.biorxiv.org

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Reposted by Jesse M. Shapiro

Fabrice Jean-Pierre @fabricejpierre.bsky.social · 9d

Plus que 10 jours avant la fin des soumissions des résumés pour le BiSP qui aura lieu le 5-6 novembre 2025 à l'Université de Sherbrooke. Nous aurons aussi la chance de recevoir @lalouxlab.bsky.social et @bjesseshapiro.bsky.social

Partagez! @micrhub.bsky.social

event.fourwaves.com/bispmicrhubs...

BiSP - MicrHub

Fourwaves - BiSP - MicrHub

event.fourwaves.com

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Jesse Shapiro @bjesseshapiro.bsky.social · 13d

I can send photos next week. And DNA extracts if you want.

Jesse Shapiro @bjesseshapiro.bsky.social · 13d

Yep. Evidence for kin selection in action.

Jesse Shapiro @bjesseshapiro.bsky.social · 13d

How did you get into our shared office kitchen without card access Willem?!

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Jesse Shapiro @bjesseshapiro.bsky.social · 14d

Leaky pipes, happy trees!

www.montrealgazette.com/news/article...

Jesse Shapiro @bjesseshapiro.bsky.social · 14d

Wow, superb thread Zam! I think we have our journal club paper for next week =)

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Reposted by Jesse M. Shapiro, Simon Roux, José R. Penadés

Zamin Iqbal @zaminiqbal.bsky.social · 14d

Delighted to see our paper studying the evolution of plasmids over the last 100 years, now out! Years of work by Adrian Cazares, also Nick Thomson @sangerinstitute.bsky.social - this version much improved over the preprint. Final version should be open access, apols.
Thread 1/n

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Reposted by Jesse M. Shapiro

The Carlson Lab @ Yale @carlsonlab.bsky.social · 14d

🚨 We're about to start reviewing applications, but there's still time to reach out for our postdoc position on climate change impact attribution! If you have experience with attribution science or climate epidemiology, and want to help us launch the Global Burden of Climate Change Study, reach out!

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Susan Kaye Quinn is Writing Solarpunk 🌞🌱 @susankayequinn.bsky.social · 15d

They've lost the 9yos

JA Westenberg
@Daojoan@mastodon.social

My 9 year old and his classmates have started using “that’s AI” to mean “I don’t believe you.”

Me: we’re having dinosaur meat for dinner

Kiddo: that’s AI
Sep 24, 2025, 07:36 AM

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Reposted by Jesse M. Shapiro, Alan McNally

Jeremy Barr @jeremyjbarr.bsky.social · 15d

Excited to annouce the latest research published by our lab, which is led by Dinesh Subedi and is out today in Nature Microbiology.

www.nature.com/articles/s41...

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections - Nature Microbiology

The Entelli-02 phage product containing five phages has frontline potential to address infections caused by the multidrug-resistant Enterobacter cloacae complex.

www.nature.com

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Reposted by Jesse M. Shapiro, Larry W. Hunter

Pascal Mamassian @mamassian.bsky.social · 15d

A nice shift in perceived colour between central and peripheral vision. The fixated disc looks purple while the others look blue.

The effect presumably comes from the absence of S-cones in the fovea.

From Hinnerk Schulz-Hildebrandt:
arxiv.org/pdf/2509.115...

An array of 9 purple discs on a blue background. Figure from Hinnerk Schulz-Hildebrandt.

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Jesse Shapiro @bjesseshapiro.bsky.social · 16d

I was just typing “French Tacos” but you beat me to it