Larry Hunter
banner
proflhunter.bsky.social
Larry Hunter
@proflhunter.bsky.social

Knowledge based biomedical data science, artificial intelligence for discovery in molecular biomedicine, computational bioethics, theory of mattering. University of Chicago / Big Island HI

Business 36%
Biology 15%

“Science is doing OK,” [AAAS spokesperson says] “Things are not bad at all, given our expectations.”

www.nytimes.com/2026/01/10/s...
Congress Is Reversing Trump’s Steep Budget Cuts to Science
www.nytimes.com

Reposted by Larry W. Hunter

Hot Mantle Melt

Tomorrow is final day of volcano adventure. Still hoping for the Kīlauea Episode 40 fountaining event.

I’ve seen a lot of lava. But I really just want to see an arc of magma fly & fall across the sky.

Reposted by Larry W. Hunter

Hawai’i pop up in Waikaloa on the Big Island.

Reposted by Larry W. Hunter

Some folks have wanted to list Claude as a co-author on @arxiv.bsky.social submissions, which is not permitted. But if it had been allowed, so many Claude-written papers have been rejected at this point, that Claude would be banned from the platform
Best TikTok thing going is the two dudes trying food from every country without leaving NYC. If you haven’t seen them yet, it’s incredible. My favorite so far is last week’s. Legit got me emotional.

This is such an important point. #PSB2026 -- a scientific meeting with lots of AI & biomedicine researchers -- was full of this sort of anthropomorphizing language. We as researchers need to be much more careful!

And I have been citing that Drew McDermott article forever. It's great throughout.
Anthropomorphizing language can be cute when applied to your favorite car, but it helps to muddy the discourse when applied to tech sold as "AI". New from me & @nannainie.bsky.social on @techpolicypress.bsky.social -- how to spot & revise away from anthropomorphizing language applied to "AI"
We Need to Talk About How We Talk About 'AI' | TechPolicy.Press
We share a responsibility to create and use empowering metaphors rather than misleading language, write Emily M. Bender and Nanna Inie.
www.techpolicy.press
After 5 years of data collection, our WARN-D machine learning competition to forecast depression onset is now LIVE! We hope many of you will participate—we have incredibly rich data.

If you share a single thing of my lab this year, please make it this competition.

eiko-fried.com/warn-d-machi...
WARN-D machine learning competition is live » Eiko Fried
If you share one single thing of our team in 2026—on social media or per email with your colleagues—please let it be this machine learning competition. It was half a decade of work to get here, especi...
eiko-fried.com
Anthropomorphizing language can be cute when applied to your favorite car, but it helps to muddy the discourse when applied to tech sold as "AI". New from me & @nannainie.bsky.social on @techpolicypress.bsky.social -- how to spot & revise away from anthropomorphizing language applied to "AI"
We Need to Talk About How We Talk About 'AI' | TechPolicy.Press
We share a responsibility to create and use empowering metaphors rather than misleading language, write Emily M. Bender and Nanna Inie.
www.techpolicy.press

My attempt at retirement was a total failure. After I left, I continued to advise trainees and publish papers. After a few months, I realized the only thing that changed in my life was the pay and I "unretired."
Letter of resignation from @jennifer-troyer.bsky.social former Dir of Extramural Ops at NHGRI

"The NIH is not only no longer the organization that I love but is now an organization that I can no longer be a part of and retain my integrity and self-respect."

www.linkedin.com/posts/jennif...

1/6
Letter of resignation | Jennifer Troyer
Reposting: As many of you know, I recently chose to leave the position I worked hard to achieve, the work that I love, and the team of people that could not have been better to do this work with. It ...
www.linkedin.com

I'm no expert, and am mostly vegetarian with some dairy myself. I do know a number of cognitively normal vegans, though.

I loved this 🧵.

I was peripherally involved with both "mainstream" (ha!) and contact juggling communities, but had no idea the complicated history!
This is contact juggling. There's maybe a few hundred people in the world for whom contact juggling has at one point been their primary source of income, and most of us know each other. It coalesced as an art from in the 1980s and got its name in 1990, though it pulls from practices far older.

"There is no evidence of adverse effects on health or cognitive function with lower DHA intake in vegetarians." pubmed.ncbi.nlm.nih.gov/19500961/
DHA status of vegetarians - PubMed
Preformed DHA in the diet of omnivores explains the relatively higher proportion of this fatty acid in blood and tissue lipids compared with vegetarians. The pathophysiological significance of this difference remains to be determined.
pubmed.ncbi.nlm.nih.gov
The district court injunction that prevented NIH from capping indirects at 15% was upheld today on appeal!

www.reuters.com/world/trump-...
Trump administration cannot slash NIH research funding, court rules
District Judge Angel Kelley last year blocked the cuts, and on Monday the appeals court agreed.
www.reuters.com
This is contact juggling. There's maybe a few hundred people in the world for whom contact juggling has at one point been their primary source of income, and most of us know each other. It coalesced as an art from in the 1980s and got its name in 1990, though it pulls from practices far older.

Reposted by Larry W. Hunter

#MachineLearning researchers: Join us at @msftresearch.bsky.social #ArtificialIntelligence for Science to push the frontier of AI for molecular Biology or AI for Chemistry. Work with @marwinsegler.bsky.social or my team in Berlin, Cambridge or Amsterdam.

apply.careers.microsoft.com/careers/job/...
Senior Machine Learning Researcher - MSR AI for Science | Microsoft Careers
Invent novel deep learning techniques for models of (bio)molecular structure, dynamics, reactivity and function. Design, implement, and iterate on model architectures and training algorithms (e.g., di...
apply.careers.microsoft.com

Mildred Cho's #PSB26 Teri Talk:

Will Generative AI Ruin Science?

Eric Green’s title

Phil Bourne (virtually) introducing Eric Green's PSB keynote

#psb26 @pacsym.bio

First day of PSB plenary getting under way. @pacsym.bio #psb26 to follow...

Reposted by Larry W. Hunter

Naively, I never considered it - if we are to successfully ‘colonise’ space we need to get much better at understanding & building functional ecosystems that include recycling & environmental regulation.
We know how to build rockets; time to better understand biology
🧪
economist.com/leaders/2025...
The future of space exploration depends on better biology
Rockets are great, but sewage treatment is what you need for the long haul
economist.com

Today is the first day of #PSB2026. Looking forward to another great conference. So nice to see so many old friends.

psb.stanford.edu
PSB Home Page
psb.stanford.edu
One of the chief virtues of the book is that it’s nearly the only remaining form of media that isn’t constantly being interrupted by ads. Between the covers is the last place on earth where no one is trying to sell you shit, a place where you can still be a human being rather than a mark.
Ex-Meta chief AI scientist Yann LeCun has Lunch with the FT and in one of those instances so rare that you know he didn't sign an NDA, says exactly why as.ft.com/r/e503690d-8...

New (to me) publishing scam, clearly AI driven.

Reposted by Larry W. Hunter

Vandals. And don't believe for a second that they don't know what they're wrecking. (Gift link.) www.nytimes.com/2025/12/31/c...
NASA’s Largest Library Is Closing Amid Staff and Lab Cuts
www.nytimes.com
If you are a resident of California, the state now has a portal where you can demand deletion of your personal data from 500+ registered data brokers with a single request form, for free.

consumer.drop.privacy.ca.gov
consumer.drop.privacy.ca.gov

"Them as counts counts more than them as don't counts" is a line from Riddley Walker that has stuck with me for decades. If you do ever get sworn in for anything, I personally would not judge you for using it.

Not that anyone besides me cares, but that figure has the wrong source in the article. It's from this 2020 report www.founderspledge.com/research/cli...
Climate & lifestyle report
www.founderspledge.com

I find this article absolutely charming. I'm in @drrachelbarr.bsky.social !

"Romanticism is an act of reintegration. It’s scientists who write poetry, doctors who paint, philosophers who walk in the woods. It’s an attempt to make the world whole again."
The gall, the audacity, the gumption! 🤌✨

I learned about the 17th and 18th c. era of Romanticism yesterday. But I can impulsively initiate 21st century Romantic Resurgence within that time, I have that right. I wrote about it: substack.com/@drrachelbar...
How to Build a Romantic Resurgence
A manual for the rationally exhausted
substack.com