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Reposted by Alex Radzisheuskaya

Molecular Cell @cp-molcell.bsky.social · Aug 26

Online Now: A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision Online now:

A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase controls its stability. Loss of C41 oxidation increases p21 stability, impairs proliferation, and promotes senescence after irradiation.

dlvr.it

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Reposted by Alex Radzisheuskaya

Zierhut Lab @zierlab.bsky.social · Aug 26

Great story from our fantastic neighbour Jörg Mansfeld!

Molecular Cell @cp-molcell.bsky.social · Aug 26

Online Now: A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision Online now:

A redox switch in p21-CDK feedback during G2 phase controls the proliferation-cell cycle exit decision

ROS oxidize cell cycle proteins and regulate cell proliferation. Vorhauser et al. show that oxidation of the cyclin-dependent kinase (CDK) inhibitor p21 at cysteine 41 (C41) during the G2 phase controls its stability. Loss of C41 oxidation increases p21 stability, impairs proliferation, and promotes senescence after irradiation.

dlvr.it

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Aug 13

Registration is still open for Transcription and Chromatin UK 2025. Join our growing research community in Manchester this September!

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Aug 7

Congratulations, José and the team! 👏🏻👏🏻👏🏻

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Reposted by Alex Radzisheuskaya

Connor Rogerson @doctorconnor.bsky.social · Jul 17

🚨Transcription and Chromatin UK abstract deadline is TODAY🚨 Join us in Manchester and showcase your best science. Register for earlybird rates and submit your abstract here bit.ly/4eUl4mz

Transcription and Chromatin UK 2025

bit.ly

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Jun 26

Join us for the 2025 version of Transcription and Chromatin UK, this time in Manchester! Submit your abstract by July 17th.

Pradeepa Madapura @pradeepmadapura.bsky.social · Jun 26

Registration for Transcription and Chromatin UK is OPEN! Taking place from September 17 to 19, 2025, this conference will showcase cutting-edge research and is a ‘must-attend’ event for the UK transcription and chromatin community & both at home and abroad.
Pl register ow.ly/7QQb50W9Alo & share

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Reposted by Alex Radzisheuskaya

Kyiv Post @kyivpost.com · Jun 21

Belarus has released the husband of opposition leader Sviatlana Tsikhanouskaya — Sergei Tsikhanouski — along with several other prisoners, during Kellogg’s visit to the country.

Tsikhanouski ran for president in Belarus’s 2020 election. He was arrested and sentenced to 18 years in prison.

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Reposted by Alex Radzisheuskaya

Philip Ball @philipcball.bsky.social · Jun 13

Now I've had a chance to read Andrea Sella's article in @chemistryworld.com on why he returned his Royal Society Faraday Medal. I recommend that you read it too. It's inspiring, though inevitably also disturbing, in these troubled times.
www.chemistryworld.com/opinion/why-...

Why I returned the Faraday prize to the Royal Society

Andrea Sella explains how inaction over Elon Musk's membership motivated him to act

www.chemistryworld.com

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Reposted by Alex Radzisheuskaya

Surfin' NuRD @surfinnurd.bsky.social · Jun 11

Postdoc post in my lab from Autumn this year @lsiexeter.bsky.social @exeter.ac.uk
#Chromatin #StemCells #Enhancer #NeuralCrest #Transcription #CellFate
#NuRDIsTheWord
Apply and/or get in touch!

LSI-Exeter @lsiexeter.bsky.social · Jun 9

Looking for a Postdoc? A PDRA position is available in the LSI Exeter with Prof Brian Hendrich from September 2025. Do you have experience in mammalian stem cell culture and a solid understanding of molecular & biochemical lab techniques? Apply! Job Ref: Q05546 jobs.exeter.ac.uk/hrpr_webrecr...

Powered by MHR

jobs.exeter.ac.uk

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Jun 6

So proud of Dan for winning the poster prize — and it was his very first poster! What a great start!

QMUL Centre for Epigenetics @qmulepigenetics.bsky.social · Jun 6

Congratulations to poster prize winners Daniel Price and Maximilian H. Fitz-James and @manthan5277.bsky.social . Sponsored by @gensocuk.bsky.social and cosponsored by the @biochemsoc.bsky.social

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Reposted by Alex Radzisheuskaya

The Downs Lab @thedownslab.bsky.social · May 27

New preprint from the lab on ARID1A, G quadruplexes, and repair:
www.biorxiv.org/content/10.1...

ARID1A stabilises non-homologous end joining factors at DNA breaks induced by the G4 ligand pyridostatin

ARID1A is a subunit of the BAF chromatin remodelling complex that is frequently mutated in cancer. It is challenging to predict how ARID1A loss impacts cancer therapy response because it participates ...

www.biorxiv.org

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Reposted by Alex Radzisheuskaya

Dr Radu Zabet @raduzabet.bsky.social · Apr 4

I am recruiting for a postdoc in my lab at @blizardinstitute.bsky.social @qmulepigenetics.bsky.social to work on explainable AI/ML and epigenetics with a focus on enhancers. 3-year BBSRC funded position. A collaboration with @a-radzisheuskaya.bsky.social
qmul-jobs.tal.net/vx/mobile-0/.... Pls share.

Quick Check Needed

qmul-jobs.tal.net

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Apr 1

The Transcription and Chromatin UK Meeting is back for 2025! Don't miss out — register your interest: www.biochemistry.org/events-and-t... @biochemsoc.bsky.social

Transcription and Chromatin UK 2025

Transcription and Chromatin UK brings together the rich transcription and epigenetics community in the UK and leading experts from abroad, and will feature all aspects of transcription and chromatin r...

www.biochemistry.org

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Mar 7

Congratulations, Anestis!

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Reposted by Alex Radzisheuskaya

Timothy Snyder @timothysnyder.bsky.social · Feb 28

Here I react to the shameful encounter between American leaders and media and the Ukrainian president. No doubt there were more, but I saw five failures on our side: of hospitality, decency, democracy, strategy, and independence. Please watch and share.
snyder.substack.com/p/five-failu...

Five Failures in the Oval Office (video)

America hurt itself badly today.

snyder.substack.com

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Reposted by Alex Radzisheuskaya

Timothy Snyder @timothysnyder.bsky.social · Feb 28

Decent people thank Ukraine.

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Reposted by Alex Radzisheuskaya

Stephen Curry @scurry.bsky.social · Feb 14

Tally just ticked past 1900 signatures. Please keep spreading the word about the letter & asking people to sign. It's important to make the Royal Society aware (at their meeting on 03 March) just how much the scientific community wants them to speak up for their values. forms.gle/SfsDemyS8QhP...

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Reposted by Alex Radzisheuskaya

Ronan Broderick @brodericklab.bsky.social · Jan 31

My lab is #hiring!

I am recruiting for two #Postdoc positions investigating the Alternative Lengthening of Telomeres mechanism.

www.jobs.ac.uk/job/DLO693/r...

www.jobs.ac.uk/job/DLP016/r...

#Telomere #DNAreplication #DNArepair #cancer #glioma #UKRI #MRC #universityofbirmingham #NGS

Research Fellow at University of Birmingham

Discover an exciting academic career path as a Research Fellow at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

www.jobs.ac.uk

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Reposted by Alex Radzisheuskaya

The Downs Lab @thedownslab.bsky.social · Dec 13

We are looking for someone to join our lab as a researcher (scientific officer). Advert and information on applying is here: jobs.icr.ac.uk/vacancies/10...
It's a great team and a wonderful place to work!

Scientific Officer - Epigenetics and Genome Stability in Chelsea | The Institute of Cancer Research

View details and apply for this Scientific Officer - Epigenetics and Genome Stability vacancy in Chelsea . Salary : Commencement on the salary range is subject to comparable skills and exp...

jobs.icr.ac.uk

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Dec 3

Congratulations! Very well-deserved!

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Reposted by Alex Radzisheuskaya

Kristian Helin @helink.bsky.social · Nov 14

Follow the Institute of Cancer Research on our new Bluesky account. Moving from X -
@icrlondon.bsky.social

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Alex Radzisheuskaya @a-radzisheuskaya.bsky.social · Nov 12

Thank you for putting this together, Duncan and Radu. Could you please add me?

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