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Reposted by Dr Radu Zabet

Guillaume Bourque @guilbourque.bsky.social · 10h

🚨 New paper alert on telomeres! 🚨
Something different from the group! Thanks to Yuxin, a talented student in the lab, we used long-reads in 75 human trios to study telomeres and their inheritance.

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Reposted by Dr Radu Zabet

Barral Lab @barrallab.bsky.social · 9h

Looking for a PhD for 2026? We have 2 projects in collaboration with Clare Bennett (UCL) looking at macrophage metabolism in breast cancer. Check them out! @cruk-cityoflondon.bsky.social

www.colcc.ac.uk/2026-phd-pro...

crukradnet.colcc.ac.uk/phd-students...

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Reposted by Dr Radu Zabet

Rob Klose @robklose.bsky.social · 1d

Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!

jobs.jic.ac.uk/Details.asp?...

John Innes Centre

jobs.jic.ac.uk

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Reposted by Dr Radu Zabet

Aleksander Szczurek @aleksszczurek.bsky.social · 1d

If you are a computational biologist come, apply and join Howard & Klose lab in a joint Norwich-Oxford collaboration on chromatin dynamics!

John Innes Centre @johninnescentre.bsky.social · 2d

VACANCY - We have an opportunity for a Postdoctoral Researcher to join the Howard Group, working to develop computational models of epigenetic dynamics in the Polycomb system.

www.jic.ac.uk/vacancies/po...

Closing date - 9 November 2025
Salary - £37,500 - £45,350
Contract - 36 months, full-time

Postdoctoral Researcher (Howard Group) | John Innes Centre

An exciting opportunity has arisen for a Postdoctoral Researcher to join the Howard Group at the John Innes Centre, working on cutting-edge science in the field of Computational and Systems Biology.

www.jic.ac.uk

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Reposted by Dr Radu Zabet

Gurdon Institute, University of Cambridge @gurdoninstitute.bsky.social · 1d

It is with great sadness that we share the news of the death of our founder, colleague, mentor and friend, Professor Sir John Gurdon. His vision and dedication will continue to inspire generations of scientists.
🔗 www.gurdon.cam.ac.uk/nobel-laurea...

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Reposted by Dr Radu Zabet

Nuria Lopez-Bigas @nlbigas.bsky.social · 23h

🚨 New paper alert!

Sex and smoking bias in the selection of somatic mutations in human bladder

www.nature.com/articles/s41...

by @raquelbmi.bsky.social, @ferriol.bsky.social et al (in collaboration with Rosana Risques lab in @uwmedicine.bsky.social)

Sex and smoking bias in the selection of somatic mutations in human bladder - Nature

Sex bias and association with smoking history identified in the landscape of driver mutations and clonal expansions in normal human bladder tissue may explain the higher bladder cancer risk in men and smokers.

www.nature.com

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Reposted by Dr Radu Zabet

Duncan Sproul @sproullab.bsky.social · 2d

@alexisbarr.bsky.social does some very cool work. Do apply if you are looking for a postdoc!

Alexis Barr @alexisbarr.bsky.social · 20d

@mariasecrier.bsky.social & I are looking for an enthusiastic & excellent data scientist for a 4-year postdoc to understand cell cycle dysregulation in cancer.

Deadline 15th October. Get in touch if you have any questions.

Please repost!

More details:
www.imperial.ac.uk/jobs/search-...

Description

Please note that job descriptions are not exhaustive, and you may be asked to take on additional duties that align with the key responsibilities ment...

www.imperial.ac.uk

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Reposted by Dr Radu Zabet

Nature @nature.com · 3d

BREAKING: The Nobel Prize in Physiology or Medicine has been awarded jointly to Mary E. Brunkow, Fred Ramsdell, and Shimon Sakaguchi "for their discoveries concerning peripheral immune tolerance"

Stay tuned for more.
#NobelPrize

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Reposted by Dr Radu Zabet

Anders H. Lund @andershlund.bsky.social · 5d

We have an open group leader position in diabetes 1 research.
Please circulate!

www.nature.com/naturecareer....

164887 Professor or Associate Professor and Research Group Leader with special focus on molecular me - Copenhagen, Hovedstaden (DK) job with The Biotech Research and Innovation Centre (BRIC), Universi...

BRIC wishes to recruit a strongly motivated scientist at Associate Professor or Professor level for an independent research group leader position. ...

www.nature.com

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Reposted by Dr Radu Zabet

Elizabeth McKenna @elizsmckenna.bsky.social · 5d

Now online in Cancer Discovery @aacrjournals.bsky.social: Epigenetic and Transcriptional Programs Define #Osteosarcoma Subtypes and Establish Targetable Vulnerabilities - by Eunice López-Fuentes, Alejandro Sweet-Cordero, and colleagues doi.org/10.1158/2159... @ucsfchildrens.bsky.social

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Reposted by Dr Radu Zabet

Rita Strack @ritastrack.bsky.social · 8d

Please start following @natbiomedeng.nature.com! It's an alive account now and we will start posting good content!

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Reposted by Dr Radu Zabet

Mcclelland lab @mcclellandlab.bsky.social · 8d

Come and join us at the Barts Cancer Institute @qmbci.bsky.social ! Our medical school, part of Queen Mary University of London @qmulfmd.bsky.social is hiring 10 professors!! www.veredus.co.uk/job/job-747a/. Contact me for a chat if interested.

Professors x 10, Faculty of Medicine & Dentistry | Veredus

QUEEN MARY UNIVERSITY OF LONDON Professors x 10, Faculty of Medicine and Dentistry London Competitive Remuneration Package Queen Mary University of London seeks up to 10 world-leading translational re...

www.veredus.co.uk

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Reposted by Dr Radu Zabet

Wolfgang Huber @wkhuber.bsky.social · 10d

Do you like theoretical biology, mathematical&conceptual modelling and want to apply yourself to cutting-edge research at all levels of biology, from molecules to ecosystems?

Come to EMBL! Scope includes physics-based models, emergence, statistics, ML/AI
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

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Reposted by Dr Radu Zabet

Tobias Warnecke @tobiaswarnecke.bsky.social · 10d

Become my colleague @oxfordbiochemistry.bsky.social !
2 Associate Professorships in the areas of
- prokaryotic/eukaryotic microbiology
- metabolism

my.corehr.com/pls/uoxrecru...

Job Details

my.corehr.com

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Reposted by Dr Radu Zabet

Jamie Hackett @jamiehackett.bsky.social · 12d

❓Can a father’s environmental exposures before conception influence their offspring?

We systematically tackled this - identifying effects of paternal age, environment and genetics on early embryos - as well as confounding influences

www.embopress.org/doi/full/10....

Embryonic signatures of intergenerational epigenetic inheritance across paternal environments and genetic backgrounds | The EMBO Journal

imageimagePaternal environmental exposures have been linked with modulation of phenotype and disease risk in offspring via largely unclear mechanisms. This study employs in vitro fertilization and sin...

www.embopress.org

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Reposted by Dr Radu Zabet

Jason Moore @moorejh.bsky.social · 12d

Application period for the Cedars-Sinai PhD Program in Health AI is now OPEN! Come study cutting-edge AI in a top hospital with clinical rotations, clinical collaborators, & easy access to clinical data - please RP! www.cedars-sinai.edu/education/gr... #artificialintelligence #bioinformatics #phd

PhD in Health Artificial Intelligence

www.cedars-sinai.edu

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Reposted by Dr Radu Zabet

Seema Sheth @seemasheth.bsky.social · 12d

Tenure-track Assistant Professor position in Bioinformatics in the Department of Biology at the University of San Francisco
usfca.wd5.myworkdayjobs.com/en-US/USF_Fu...

Assistant Professor, Tenure-Track, Department of Biology, University of San Francisco

Job Title: Assistant Professor, Tenure-Track, Department of Biology, University of San Francisco Job Summary: The Department of Biology at the University of San Francisco invites applications for a fu...

usfca.wd5.myworkdayjobs.com

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Reposted by Dr Radu Zabet

Craig Kaplan @triggerloop.bsky.social · 13d

This is a fascinating paper that particular types of RNA binding proteins with IDRs that target nuclear speckles also can recruit their own RNAs to nuclear speckles as a negative feedback mechanism for condensation the authors call "interstasis" www.nature.com/articles/s41...

Collective homeostasis of condensation-prone proteins via their mRNAs - Nature

The authors discover a homeostatic process termed interstasis, in which an increased concentration of proteins within RNA–protein condensates induces the sequestration of their own mRNAs.

www.nature.com

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Reposted by Dr Radu Zabet

Carmelo Ferrai @carmeloferrai.bsky.social · 14d

@jzylicz.bsky.social N. Stamidis @ucph.bsky.social @jamiehackett.bsky.social @gregersenlab.bsky.social

HDAC3 prevents enhancer hyperactivation to enable developmental transitions

www.biorxiv.org/content/10.1...

HDAC3 prevents enhancer hyperactivation to enable developmental transitions

Dynamic gene regulation requires precise cooperation between transcription factors and chromatin modifiers at regulatory elements to achieve not only activation or repression, but also appropriate tra...

www.biorxiv.org

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Reposted by Dr Radu Zabet

Carlos Caldas 🇵🇹🇮🇱🇪🇺🇬🇧🎗 @carloscaldas1960.bsky.social · 14d

A fantastic Institute led by a true Physician-Scientist!
@cruk-mi.bsky.social

Cancer Research UK Manchester Institute @cruk-mi.bsky.social · 15d

Exciting news - we are recruiting new Group Leaders! 🥼

We are seeking to appoint exceptional early-career scientists & clinician scientists as #GroupLeaders to develop bold, innovative, high-impact #CancerResearch programmes

Full details on our website: www.cruk.manchester.ac.uk/career/new-g...

Group Leader Recruitment at the Cancer Research UK Manchester Institute

YouTube video by CRUK Manchester Institute

youtu.be

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Reposted by Dr Radu Zabet

Steffen Scholpp @scholpplab.bsky.social · 14d

Want to help prevent aggressive NF1 cancers using cutting-edge models? The GW4 BioMed2 MRC DTP is offering a fully funded 4-year PhD @lsiexeter.bsky.social @exeter.ac.uk to develop a humanised zebrafish model for NF1 resilience.
Apply by 20 Oct 2025
www.exeter.ac.uk/study/fundin...
#PhD #biomed

PhD:GW4 BioMed2 MRC DTP Studentship | University of Exeter

  The GW4 BioMed2 MRC DTP is offering up to 17 funded studentships across a range of biomedical disciplines, with a start date of October 2026.

www.exeter.ac.uk

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Reposted by Dr Radu Zabet

Luca Giorgetti lab @FMI @lucagiorgetti.bsky.social · 14d

Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇

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Alexis Verger 🧬🧫🧪 @alexis-verger.cpesr.fr · 15d

Emergence of activation or repression in transcriptional control under a fixed molecular context www.pnas.org/doi/10.1073/...

Emergence of activation or repression in transcriptional control under a fixed molecular context | PNAS

Transcription factors (TFs) can be both activators and repressors of gene transcription. This can manifest as “duality,” where the transcriptional ...

www.pnas.org

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Reposted by Dr Radu Zabet

New Phytologist @newphyt.bsky.social · 15d

DNA methylation contributes to plant acclimation to naturally fluctuating light

📖 buff.ly/3QP9OJ5
by Emmerson et al.

@robynemm.bsky.social @raduzabet.bsky.social @ubechtold.bsky.social @proftlawson.bsky.social #PlantScience

Schematic representation of the experimental design used in this study.

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Reposted by Dr Radu Zabet

Noonan Lab @noonanlab.bsky.social · 15d

Out in Cell Genomics: A comprehensive analysis of the cell-type-specific effects of CHD8 loss of function on gene expression in the embryonic and juvenile mouse cortex. Thread 🧵:
www.cell.com/cell-genomic...

Cell-type-specific dysregulation of gene expression due to Chd8 haploinsufficiency during mouse cortical development

Yim et al. use single-cell transcriptomics to elucidate the molecular outcomes of Chd8 haploinsufficiency in the mouse cortex. Their results provide insight into dynamic, cell-type-biased transcriptio...

www.cell.com

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