Lightnews — Scholar-powered news

Reposted by adam grieve

Microsoft Research @msftresearch.bsky.social · Jul 10

Today in the journal Science: BioEmu from Microsoft Research AI for Science. This generative deep learning method emulates protein equilibrium ensembles – key for understanding protein function at scale. www.science.org/doi/10.1126/...

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Mathew Kiang @mathewkiang.com · Jun 25

Karolinska is looking for 20 (!!) assistant professors and offering 6 year appointments with ~1M USD startup packages.

ki.se/en/about-ki/...

Call for 20 Assistant Professor positions

Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

ki.se

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adam grieve @adamgrieve.bsky.social · Jun 24

This sounds like a fun job!

Derivery Lab - MRC LMB @deriverylab.bsky.social · Jun 23

🚨 JOB ALERT 🚨
We're hiring a Research Assistant – no PhD needed!
Join us to explore the molecular mechanisms of receptor sorting in endosomes.
Experience in protein expression/purification, cloning & cell culture desired 🧫🔬
Apply now 👉 www.nature.com/naturecareer...

#STEMCareers #ResearchJobs

A picture of 3 rows of people on steps at the MRC LMB. From left to right - top row: Akaash, Vic, Lara - Middle row: Kerrie, Manu, Paddy - bottom row: Meg and Julie

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Britt Lundgren @brittlundgren.bsky.social · May 29

Are you a PI of a federal grant cancelled by the Trump administration?

Please share your info with the Democratic Staff of the House Committee on Science, Space, and Technology, who launched this portal yesterday to track funding cancellations 🔭🧪

forms.office.com/pages/respon...

Grant Cancellation Web Form

WAS YOUR GRANT CANCELED BY PRESIDENT TRUMP?

The Committee on Science, Space, and Technology, Democratic Staff, is surveying the impact of the Trump Administration’s cancelation of federal research awards. If your award was terminated since January 20, 2025, please fill out this brief survey. If you had multiple awards terminated, please fill out a separate form for each award. While anonymous submissions will be helpful to the Committee’s efforts, we encourage you to leave your contact information if you are open to having a confidential conversation with Committee staff. Please find our confidentiality policies at the following link – any information you share will be treated with these protections, regardless of your current affiliation with any current or former funding agency: https://democrats-science.house.gov/contact/whistleblower

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Ben Langmead @benlangmead.bsky.social · May 29

Industry friends, now is the time for MUCH more speaking out on behalf of academic colleagues under duress. Here are core open source methods that many of your products doubtlessly depend on either directly or indirectly (see en.wikipedia.org/wiki/HMMER) being abruptly defunded. Make noise.

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Verena Kohler @verenakohler.bsky.social · Apr 18

🔬 Hiring: Postdoctoral Fellow

Seeking a bioinformatician/screening expert to be part of our team running genome‑wide screens, building data‑integration pipelines & validating hits in higher organisms.

🌱 2‑yr fellowship with tailored mentorship, leadership & science‑communication training

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Anna Bodzeta @annabodzeta.bsky.social · Apr 10

Come and join us in solving mystery of plasma membrane proteostasis in beautiful neurons.

adam grieve @adamgrieve.bsky.social · Apr 9

Pls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!

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adam grieve @adamgrieve.bsky.social · Apr 9

Pls re-skeet! There's a postdoc job available to join us in Bristol! We're looking for a molecular cell biologist to help us investigate plasma membrane proteostasis in neurons. Apply here by 23 April: www.jobs.ac.uk/job/DMO097/r.... If interested, do contact me and check out grieve-lab.com! Thanks!

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Michael Way @drmichaelway.bsky.social · Apr 7

A fitting announcement to an outstanding scientist and friend who is dearly missed by many. journals.biologists.com/jcs/article/...

Announcing the JCS–David Stephens Prize and the 2024 winner Anja Konietzny

Over the past 25 years, Journal of Cell Science (JCS) has been awarding a prize of £1000 – ‘The JCS Prize’ – to the first author(s) of the paper that is judged by the Editors to be the best paper publ...

journals.biologists.com

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Thom Sharp @thomsharp.bsky.social · Apr 9

Our new lab website is online!

sharplab.uk

Check it out and learn more about our research in Bristol!

Protein structure of C1 bound to IgM antibodies

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Camilla Godlee @camillagodlee.bsky.social · Mar 31

I am recruiting a research assistant. Please send to anyone you know who is interested in gaining more lab experience in host:pathogen interactions of bacterial infections.

www.jobs.cam.ac.uk/job/50738/

Research Assistant - Godlee Group (Fixed Term) - Job Opportunities - University of Cambridge

Research Assistant - Godlee Group (Fixed Term) in the Department of Biochemistry at the University of Cambridge.

www.jobs.cam.ac.uk

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Aakriti Jain @aakritijain.bsky.social · Mar 27

SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...

Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...

www.science.org

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Robin Corey @robincorey.bsky.social · Mar 27

Check out our new paper with Michael Landreh, @pstansfeld.bsky.social and others in @elife.bsky.social : Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization doi.org/10.7554/eLif...

Engineering cardiolipin binding to an artificial membrane protein reveals determinants for lipid-mediated stabilization

doi.org

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Andrew Porter @retropz.bsky.social · Mar 24

Applications close today for this @uniofmanchester.bsky.social #DigitalNotebook #Metascience project, seasoned with #OpenResearch & served with helpings of #ResearchIntegrity and a side of #ResearchCulture

Full details of everything on the menu below 👇

www.jobs.manchester.ac.uk/Job/JobDetai...

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adam grieve @adamgrieve.bsky.social · Mar 23

Thank you Ines! I had such a lovely time visiting sunny York this week, sharing our science and chatting cell bio, neuroscience and proteases. Thanks for the invite, special thanks to the one and only @yorkyeast.bsky.social for top-notch hosting!

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Iris @irismarchal.bsky.social · Mar 18

Nanopore technology might be able to sequence proteins soon! Read about the road ahead in this exciting Perspective rdcu.be/edWPi in @naturebiotech.bsky.social

Toward single-molecule protein sequencing using nanopores

Nature Biotechnology - Maglia and colleagues discuss advances in nanopore technology en route to single-molecule protein sequencing

rdcu.be

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Ali Twelvetrees @dozenoaks.bsky.social · Mar 6

Do you need some science joy in your life? Do you like neurons? Maybe glia? Molecules? Cell biology? Save the date for #NeuroBioUK25 - the venue is booked and we are excited to see you and your incredible science there on the 12th of September!

neurobiouk.sites.sheffield.ac.uk

An image montage advertising NeuroBioUK - 12th of September 2025 in York. The image is York cathedral superimposed over a fluorescent cortex mouse section coloured to look a bit like a dawn sky.

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Ines Hahn @exdrososcientia.bsky.social · Mar 6

Save the date: We're excited that the third NeuroBioUK will take place on September. Block it in your calendar to join us in York for a fun day of neurons, glia, cool science and chats!

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Joan Chang @tranejoan.bsky.social · Mar 5

Our lab's #1st manuscript from our #1st #PhD Katie is on #bioRxiv! Check it out 👇🏻

#macrophage regulation of fibroblast #collagen #circadian rhythm. #ImmunoECMatrix w/ @profandrewmac.bsky.social @tracyh9494.bsky.social @mcrcellmatrix.bsky.social @mcf-uom.bsky.social

www.biorxiv.org/content/10.1...

Macrophages promote collagen deposition through circadian regulation of fibroblasts

Collagen deposition in fibroblasts, the primary collagen-producing cells, is regulated by both macrophages and the circadian rhythm, although how these regulatory processes interact with one another i...

www.biorxiv.org

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adam grieve @adamgrieve.bsky.social · Dec 18

Exciting opportunity in the newly minted McMillan lab in Liverpool. Kirsty is a great scientist and a top mentor for students - if you’re looking for a PhD and are interested in trafficking and neurodegeneration, do contact her!

Kirsty McMillan @mcmillanlab.bsky.social · Dec 18

I have a funded PhD studentship available to start in my new lab in 2025! If you are interested in Endosomal Biology, Astrocytes and Alzheimer’s Disease have a look:
www.findaphd.com/phds/project...

Please feel free to share.

The Role of the Endosomal System in Alzheimer’s Disease. at University of Liverpool on FindAPhD.com

PhD Project - The Role of the Endosomal System in Alzheimer’s Disease. at University of Liverpool, listed on FindAPhD.com

www.findaphd.com

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adam grieve @adamgrieve.bsky.social · Dec 10

Thanks Loges, very kind of you!

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Jez Carlton @jezcarlton.bsky.social · Nov 25

UK Membrane Trafficking 2024

Who doesn’t like a deadline that gets brought forward?

Please register by 3rd December - King’s need longer to make the sandwiches than I previously thought!

estore.kcl.ac.uk/conferences-...

Programme coming soon!

UK Membrane Trafficking Meeting 2024 | King's College London eStore

Registration for the 2024 UK Membrane Trafficking Meeting, held at KCL.  Registration per person, to include sandwich lunch and coffee breaks and even

estore.kcl.ac.uk

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adam grieve @adamgrieve.bsky.social · Nov 27

Amazing PhD opportunity to join an exciting new lab at Bristol Biochemistry - send your best students in Ferdos’ direction!

Ferdos Abid Ali @abidalilab.bsky.social · Nov 27

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

This scheme shows the cargo adaptor FHF in the middle with arrows pointing to distinct microtubule and actin-based motors (dynein-dynactin, KIFC1, KIF1C and myosins V, IX and X as well as Tropomyosin 1). It also shows a link to Rab5 marked early endosomes. The hypothesis is that FHF coordinates multi motor binding at the early stages of endocytosis. The PhD project would address the hierarchy of motor binding and how these motors coordinate to allow the newly formed vesicle to transition from the actin to MT cytoskeletal network.

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Ferdos Abid Ali @abidalilab.bsky.social · Nov 27

If you’re interested in how molecular motors coordinate to power intracellular trafficking events (e.g. endocytosis), I’ve got a PhD position available to study this at vibrant Bristol uni. In this project, we will capture highly dynamic events by #cryoEM, single molecule imaging & cell biology. 🔬❄️🧪

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adam grieve @adamgrieve.bsky.social · Nov 15

Can I ask you to share a PhD advert at Bristol Uni please? Rhomboid proteases play a role in neurons that is essential for life- but it is not characterised. Got a student interested in cell biology, electrophysiology and neurobiology? Send them our way! tinyurl.com/56f24f7c

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