Alon Goren
@agoren.bsky.social
65 followers 76 following 18 posts
Assoc Prof. @UCSanDiego, Dept of Medicine. Developmental epigenomics: merging molecular biology, genomics, bioinformatics & tech-dev. He/Him
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Reposted by Alon Goren
brsoucek.bsky.social
Strong statement today from UC's Academic Senate:
Reposted by Alon Goren
governor.ca.gov
IF ANY CALIFORNIA UNIVERSITY SIGNS THIS RADICAL AGREEMENT, THEY'LL LOSE BILLIONS IN STATE FUNDING — INCLUDING CAL GRANTS — INSTANTLY.

CALIFORNIA WILL NOT BANKROLL SCHOOLS THAT SELL OUT THEIR STUDENTS, PROFESSORS, RESEARCHERS, AND SURRENDER ACADEMIC FREEDOM.
New York Times: "Trump Administration Asks Colleges to Sign ‘Compact’ to Get Funding Preference."

The White House asked nine top universities to pledge support for President Trump’s agenda to help ensure access to research funding.
Reposted by Alon Goren
lucas.farnunglab.com
New week, new tool: Find our Protein Domain Designer tool to generate publication-ready protein domain diagrams here: domaindesigner.farnunglab.com
Protein Domain Designer tool for the generation of publication-ready protein domain diagrams
Reposted by Alon Goren
Reposted by Alon Goren
odedrechavi.bsky.social
"Did I remove track changes?"
Reposted by Alon Goren
Reposted by Alon Goren
odedrechavi.bsky.social
How every PhD project develops
agoren.bsky.social
I am thrilled to share a joint work with Melissa Gymrek that spans several years to study what is the impact of promoter proximal short tandem repeats (STRs) on expression by using MPRAs. I am sure you'd enjoy!
Awesome effort by @xzhangbsky.bsky.social and the team!
www.biorxiv.org/content/10.1...
xzhangbsky.bsky.social
xzhangbsky.bsky.social
Reposted by Alon Goren
warren.senate.gov
First Colbert, now Kimmel.

Last-minute settlements, secret side deals, multi-billion dollar mergers pending Donald Trump's approval.

Trump silencing free speech stifles our democracy. It sure looks like giant media companies are enabling his authoritarianism.
Reposted by Alon Goren
wgawest.bsky.social
WGA Statement on ABC’s Decision to Pull Jimmy Kimmel Live!
The right to speak our minds and to disagree with each other - to disturb, even - is at the very heart of what it means to be a free people. It is not to be denied. Not by violence, not by the abuse of governmental power, nor by acts of corporate cowardice.
As a Guild, we stand united in opposition to anyone who uses their power and influence to silence the voices of writers, or anyone who speaks in dissent. If free speech applied only to ideas we like, we needn't have bothered to write it into the Constitution. What we have signed on to - painful as it may be at times - is the freeing agreement to disagree.
Shame on those in government who forget this founding truth. As for our employers, our words have made you rich.
Silencing us impoverishes the whole world.
The WA stands with Jimmy Kimmel and his writers.
Reposted by Alon Goren
johndoench.bsky.social
Doomscrolling pause to chat CRISPR libraries! Preprint describes our new, data-driven approach to combine on-target and off-target predictions much more intelligently for *selecting* guides, which we use to develop our newest Cas9 knockout library, Jacquere. Thread: www.biorxiv.org/content/10.1...
Balancing off-target and on-target considerations for optimized Cas9 CRISPR knockout library design
The continued development of high-dimensional CRISPR screen readouts, such as single-cell RNA sequencing and high-content imaging, necessitates compact libraries to enable functional interrogation at ...
www.biorxiv.org
agoren.bsky.social
3/3
The other authors include: Lauren Patel, Lauren Alcoser (Agilent Technologies), Eric Mendenhall, @svenheinz.bsky.social and Christopher Benner
agoren.bsky.social
We identified optimal conditions, show that double cross-linking works just as well as single for histone marks while allows capturing of other DNA-associated proteins and note an important observation regarding the ratio of antibody to cell-number (chromatin).
Reposted by Alon Goren
dgmacarthur.bsky.social
Hey Australian genetics/genomics friends: the OurDNA Symposium will be in Sydney on 14 August, just before the HGSA meeting. Learn more about inclusive recruitment for genomics and get a preview of the OurDNA variant browser! events.humanitix.com/ourdna-sympo...
OurDNA Symposium 2025: Partnering for impact
The OurDNA Symposium brings stakeholders together for important conversations about building the foundation for equitable genomics in Australia.
events.humanitix.com
Reposted by Alon Goren
Reposted by Alon Goren
itaiyanai.bsky.social
Science is absolutely key to the US's success but this government's intention to now dramatically reduce the part of the federal grants that go to the university (in addition to the researchers; the "indirects") is like removing the unseen roots of a tree and expecting it to continue to flourish.
agoren.bsky.social

Me: if you’re going to argue about it, we’ll have a shower every day.
10yo: so if I take a shower everyday that means I can be annoying and argue about it.
Me:
Reposted by Alon Goren
usha.bsky.social
Please repost! We’re trying hard to sort out rumors from truth + would like to hear from anyone affected by the new federal orders + NIH pause. Patients, scientists, health equity researchers: please contact us below. We won’t share anything without your permission. www.statnews.com/2025/01/25/t...
Are you affected by the Trump administration’s pause on health communications, science meetings, and reviews?
Have you been affected by the Trump administration’s pause on communications, science meetings, and reviews? @statnews would like to hear from you.
www.statnews.com