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Andy Webb @ajwpharm.bsky.social · 1d

Do you use vasopression for MAP augmentation in your SCI patients?

In our newly published series, we describe significant hyponatremia frequently develops when used just to push up the MAP - quite literally induced SIADH

pubmed.ncbi.nlm.nih.gov/41051384/

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Andy Webb @ajwpharm.bsky.social · 11d

Simple solution - import the safe European analgesic paracetamol!

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Andy Webb @ajwpharm.bsky.social · 20d

We're missing you here!! #NCS2025

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Andy Webb @ajwpharm.bsky.social · 22d

Excited for #NCS2025! If you're attending, be sure to participate in the @neurocritical.bsky.social Social Media Contest to potential win some great prizes - see more below

www.neurocriticalcare.org/Events/Annua...

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Andy Webb @ajwpharm.bsky.social · Aug 30

This has always perplexed me lol

Love breaking the vicious cycle of "they're agitated because of the vent" -> increased propofol -> "they need the vent because of their propofol requirement"

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Andy Webb @ajwpharm.bsky.social · Aug 28

Have you seen the new package insert tenecteplase dosing for stroke? It uses broad-stroke dose rounding that we think may put patients at risk of harm - a 40 kg patient will get a dose 50% higher than intended! See our editorial published today in Cerebrovascular Diseases

karger.com/ced/article/...

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Reposted by Andy Webb

Megan A Rech, PharmD, MSc @meganarech.bsky.social · Jul 23

Real-🌎 data in Veterans with fXaI-related ICH treated w/ andexanet alfa (AA; n=129) or 4F-PCC ( n=221)
🔷Propensity matched
🔷No difference in 90-day mortality
🔷⬆️30-day thrombotic events w/ AA (11.4 % vs. 2.4 %, p < 0.01)
Free 👉https://www.sciencedirect.com/science/article/pii/S073567572500498X

Andexanet alfa increases 30-day thrombotic events relative to four-factor prothrombin complex concentrate for factor Xa inhibitors-related intracerebral hemorrhage in veterans

Two hemostatic agents are commonly used to reverse factor Xa (fXa) inhibitor-related intracranial hemorrhage (ICH): andexanet alfa (AA) or 4-factor pr…

www.sciencedirect.com

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Reposted by Andy Webb

Antibiotic Steward 🅱️C🆔🅿️🌟 @absteward.bsky.social · Jul 20

🔥🔥Just published 🔥🔥
ATS CAP guidelines 2025
Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline
Free access pdf #IDsky#EMIMCC
www.atsjournals.org/doi/10.1164/...

Diagnosis and Management of Community-acquired Pneumonia. An Official American Thoracic Society Clinical Practice Guideline | American Journal of Respiratory and Critical Care Medicine | Articles in P...

www.atsjournals.org

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Andy Webb @ajwpharm.bsky.social · Jun 21

Ah nothing quite as useless as a clonidine patch being ordered for acute agitation

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Reposted by Andy Webb

Neurocritical Care @neurocritcarej.bsky.social · Jun 12

Webb et al: Clinical Consequences of Disproportionate Free Valproate Elevation in Critically Ill Adult Patients: A Multicenter Retrospective Cohort Study

Link: link.springer.com/ar...

@neurocritical #neurocritcare

@AJWPharm

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Andy Webb @ajwpharm.bsky.social · Jun 11

Excited to be speaking for @neurocritical.bsky.social on the treatment of SE with some phenomenal co-presenters. The Masterclass will have an interactive portion where participants can ask questions and join in discussion about treatment controversies!

www.neurocriticalcare.org/NCS-Learning...

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Andy Webb @ajwpharm.bsky.social · Jun 8

These cases are brutal. If you can get them through the worst of it, I've seen some incredible recoveries even after being in a coma for 1-2+ weeks

We will sometimes use siltuximab (IL6 antibody) instead of tocilizumab because it avoids the theoretical IL6 sequestration risk

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Andy Webb @ajwpharm.bsky.social · Jun 8

Results of an important study

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Reposted by Andy Webb

Damien BARRAUD MD @damienbarraudmd.bsky.social · May 20

#LessIsMore
Again...
link.springer.com/article/10.1...

Efficacy of targeting high mean arterial pressure for older patients with septic shock (OPTPRESS): a multicentre, pragmatic, open-label, randomised controlled trial - Intensive Care Medicine

Purpose We examined the effect of a high-target mean arterial pressure (MAP) on septic shock in a previously underrepresented region. Methods A multicentre, pragmatic, open-label, randomised controlle...

link.springer.com

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Reposted by Andy Webb

Ashley Schenk, PharmD, BCPS, BCCP @aschenkpharmd.bsky.social · May 14

Finally made my way over to @bsky.app and the #pharmsky #cardiosky community! 🫀💊

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Andy Webb @ajwpharm.bsky.social · May 14

Our team is expanding! One of our cardiology pharmacists is moving to a clinic position full time so are recruiting an additional full FTE inpatient cardiology pharmacist.

massgeneralbrigham.wd1.myworkdayjobs.com/en-US/MGBExt...

Clinical Pharmacist, Cardiology

Site: The General Hospital Corporation Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to adva...

massgeneralbrigham.wd1.myworkdayjobs.com

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Reposted by Andy Webb

😱🩸Spooky SpectreKILLoquy 🎃🔪 @caulimovirus.bsky.social · Sep 19

I bet white coat hypertension is like a thousand times worse at the vet

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Andy Webb @ajwpharm.bsky.social · May 2

Thank you!

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Reposted by Andy Webb

josh farkas 💊 @pulmcrit.bsky.social · May 2

Pharmacists- any book recommendations for textbooks on ICU/hospital pharmacology?

I’m finishing up Critical Care Pharmacotherapy 2e by Erstad and it’s a banger, but I’d like to read a couple more books if more good ones are out there?

a cartoon of a girl holding a book with the words i love this book

ALT: a cartoon of a girl holding a book with the words i love this book

media.tenor.com

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Andy Webb @ajwpharm.bsky.social · May 2

I'm a little biased as a contributing author, but this book was recently published on critical care pharmacotherapy. It's a bit more detailed than CCP so should have some more pharmacology content, although it's not specifically a pharmacology book.

link.springer.com/book/10.1007...

The Pharmacist's Expanded Role in Critical Care Medicine

This book helps critical care pharmacists develop a clinical sense to assist with evaluation, diagnosis, and provide better pharmacotherapy interventions.

link.springer.com

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Reposted by Andy Webb

Richard Choi, DO, FNCS @rkchoi.bsky.social · Apr 30

1/ Hi 👋 #medtwitter #neurotwitter #neurocritcare #FOAMed #meded today, as your #SoMeAmbassador for @neurocritcarej we will be breaking down an oldie but goodie @neurocriticalcarej paper!
link.springer.com/ar...
Jump to 11/ for info on the paper

Association of External Ventricular Drain Wean Strategy with Shunt Placement and Length of Stay in Subarachnoid Hemorrhage: A Prospective Multicenter Study

Neurocritical Care - Survivors of aneurysmal subarachnoid hemorrhage (SAH) face a protracted intensive care unit (ICU) course and are at risk for developing refractory hydrocephalus with the need...

link.springer.com

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Andy Webb @ajwpharm.bsky.social · Apr 30

A great summary table of the available literature for neurostimulant use after stroke - lots of small, underpowered trials leave a lot to be desired when deciding whether starting a stimulant is worthwhile after stroke

www.ahajournals.org/doi/abs/10.1...

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Andy Webb @ajwpharm.bsky.social · Apr 28

@bgundiluted.bsky.social @cbthepharmd.bsky.social @meganarech.bsky.social

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Andy Webb @ajwpharm.bsky.social · Apr 28

Nifty RCT in @jama.com IM today evaluating the impact of targeted EM pharmacist intervention for patients presenting to the ED with medication related problems in France showing a dramatic ⬇️ in readmissions compared to SOC. Small and single center, but compelling!

jamanetwork.com/journals/jam...

Emergency Department Visits for Medication-Related Events With vs Without Pharmacist Intervention

This randomized clinical trial assesses the efficacy of a pharmacist-led transition of care program in reducing emergency department visits related to the same medication-related event at 6 months com...

jamanetwork.com

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Reposted by Andy Webb

Erin McCreary, PharmD @erinmccreary.bsky.social · Apr 12

@steventong.bsky.social presents the results of the PSSA domain of the SNAP 🫰 trial - the worlds largest trial of staph aureus bacteremia - at #ESCMID2025

fluclox resulted in higher mortality and more AKI compared to penicillin for PSSA

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