@alanhschulman.bsky.social
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alanhschulman.bsky.social
A mechanism that I and certainly many others have wondered about has now been revealed.
alanhschulman.bsky.social
Happy International Coffee Day. Here is a new EFSA study, but don't lose sleep over it.
efsa.europa.eu
☕ Happy #InternationalCoffeeDay

Coffee is loved worldwide — and caffeine, its key ingredient, boosts alertness in moderate amounts. But how much is safe? What are the risks?

Find out in our risk assessment: link.europa.eu/HMCRtV

#Caffeine #RiskAssessment #EFSA
A cup of coffee on a saucer with coffee beans scattered around it. The text “International Coffee Day” appears below the cup.
Reposted
plantepigenetics.ch
How about we call genome edited crops "barely mutant"?

Seems to be a nice workshop below btw!
intbarleyhub.bsky.social
Registration to the 4th International Barley Mutant 🧬Workshop #IBMW26 has opened. More info ibmw26.wordpress.com
iBMW2026
iBMW2026
ibmw26.wordpress.com
Reposted
jxbotany.bsky.social
🫛 SPECIAL ISSUE REVIEW 🫛

Johansson et al. ✍️

Redox-active molecules such as ROS, RNS, and RSS orchestrate legume responses to diverse (a)biotic stresses and symbioses, offering novel strategies to enhance crop resilience in changing environments.

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪
Fig. 1 (shortened, full legend in paper): Integration of environmental changes through dynamic RONSS interactions and redox state in legumes. Abiotic (e.g. heat, salinity, metal toxicity, and nutrient deficiency) and biotic (e.g. pathogens and symbionts) cues induce diverse reactive oxygen (superoxide anion, O2·−); hydrogen peroxide, H2O2) nitrogen (nitric oxide, NO), and sulfur (hydrogen sulfide, H2S) species (RONSS) which combine with those produced during cell function (respiration and photosynthesis). In response to these multiple stimuli, the level of RONSS signalling is strictly controlled by numerous enzymatic and non-enzymatic systems affecting synthesis (such as RBOH/SOD, NRs, and DES) and scavenging (APX, GPX, PhytoGb, and SQR).
Reposted
Reposted
theorapplgenet.bsky.social
Pangenome reveals structural variant-driven variation in expression of in winter oilseed rape. Framework enables population-scale SV-eQTL discovery beyond traditional SNP-based approaches - major advance for functional genomics.

Read more here:
Graphical pangenomics-enabled characterization of structural variant impact on gene expression in Brassica napus
rdcu.be
Reposted
somssich.bsky.social
New Zealand had some of the most restrictive laws when it came to genetically engineered food crops. This move once again demonstrates how the NZ Government makes Science-based decisions.

Take note, European Union!

#PlantGMOs #PlantNGTs #PlantScience #Agroculture #Sustainability #PlantBreeding
kwsgroup.bsky.social
NZ joins other Third Countries in updating GM labeling rules: foods made with #GenomeEditing but without new DNA will no longer require a GM label. Only products with added DNA/proteins will.
▶️ A shift toward science-based, risk-proportionate regulation!

www.nzherald.co.nz/the-country/...
Are NZ shoppers hungry for genetically-modified foods?
Gene-edited food won’t need a GM label if no new DNA was introduced during its production.
www.nzherald.co.nz
alanhschulman.bsky.social
The campaign against science by the Trump administration through grant slashing has reached FlyBase. There is an effort to crowd-fund this vital database:
hansonmark.bsky.social
A reminder you/your lab can support FlyBase at Cambridge through the following link. Every bit helps. Please share if you yourself can't donate.

www.philanthropy.cam.ac.uk/give-to-camb...
alanhschulman.bsky.social
It will depend on whether declarations are handled at the national level, what the thresholds are for EU-wide review, what the requirements are for sustainability evidence, and what the labeling and traceability rules are. There is still a lot of negotiation going on.
alanhschulman.bsky.social
Happy to announce our current scan of the risk environment for NGT (gene editing) in animals, just published today.
doi.org/10.2903/j.ef...
doi.org
alanhschulman.bsky.social
Interesting aspect to ABA: the role of poly-ubiquitination and mono-ubiquitination to post-transcriptionally regulate ABA receptors
jxbotany.bsky.social
🔍 VIEWPOINT 🔍

🌱 Precision tuning of ABA signaling by ubiquitination of ABA receptors: modulating protein activity and localization - Du & Zhang

🔗 doi.org/10.1093/jxb/...

#PlantScience 🧪
Fig. 1.Distinct ubiquitination patterns determine the protein fates of ABA receptors ER, endoplasmic reticulum; RSL1, Ring Finger of Seed Longevity 1; CUL4, CULLIN4; CDDD, COP10-DDB1-DET1-DDA1; FREE1, Fyve Domain Protein Required For Endosomal Sorting1;VPS23, Vacuolar Protein Sorting23A; ALIX, ALG-2 INTERACTING PROTEIN-X; MVB, multivesicular bodies.
Reposted
erictopol.bsky.social
Summary Table of the massive defunding of biomedical research in the United States
www.nytimes.com/interactive/...
Reposted
thomaszimmer.bsky.social
This bizarre rejection of health science is not incidental: MAGA represents a raging revolt against the very foundations of modern society which are roundly rejected as illegitimate impositions and a personal affront to the prerogative of the MAGA patriarch to decide what is true and what is real.
donmoyn.bsky.social
Cabinet officials in charge of two of America's biggest departments - including one dealing with health - don't believe germs are real.
Fox News host Pete Hegseth has said on air that he has not washed his hands for 10 years because "germs are not a real thing".

Speaking on Fox and Friends, Hegseth said the infectious micro-organisms did not exist because they could not be seen with the naked eye.

"I inoculate myself," added the Harvard and Princeton graduate.

RFK Jr. rejects cornerstone of health science: Germ theory
In his 2021 book vilifying Anthony Fauci, RFK Jr. lays out support for an alternate theory.
Reposted
alexwitze.bsky.social
Nature reporters' ongoing coverage of Trump 2.0 impacts on science and scientists is collected here: www.nature.com/collections/...

Reach me at alexwitze.01 on Signal, or witzescience[at]gmail.com, with tips, feedback, follow-ups, anything we should be covering, etc.
How Trump 2.0 is reshaping science
Since US President Donald Trump took office in January 2025, his team has made major changes to the federal government that have disrupted research and ...
www.nature.com
alanhschulman.bsky.social
Despite dire predictions, we're not there yet. But it's a cute beast and makes great copy.
carlzimmer.com
It's not a dire wolf. It's a gray wolf clone with 20 dire-wolf gene edits, and with some dire wolf traits. And here's my story! Gift link: www.nytimes.com/2025/04/07/s...
A gray wolf clone with dire wolf DNA edits.