Sobering study on the devastating impact of aid cuts on tuberculosis incidence and mortality in low and middle income countries

Governments of highest TB burden nations will need to wake up and invest more!

www.thelancet.com/journals/lan...

Reduced international donor funding through not only the termination of #USAID, but also announced reductions in donor pledges to #TheGlobalFund from other countries, could lead to substantial potential impacts on #TB morbidity and mortality.

Read how in our new study in @lancetgh.bsky.social 👇

Our work estimating the potential impacts of reductions in international donor funding for #TB is now out in @lancetgh.bsky.social:

bit.ly/3TDl28T

@raclark18.bsky.social @cfmcquaid.bsky.social @alexandra-richards.bsky.social @top-j.bsky.social @reinhouben.bsky.social @richardwhite321.bsky.social

In meta analysis of data from nearly half a million people, we found that men have higher M. #tuberculosis immunoreactivity risk than women.

Likely to be key driver of
sex differences in global tuberculosis morbidity & mortality

@hannahrickman.bsky.social 🛟🧪

authors.elsevier.com/sd/article/S...

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

World report on social determinants of health equity by the @who.int

"Conclusion: Equity is a political choice"

⬇️

This is a timely impressive report in both its breadth & depth 👏

iris.who.int/bitstream/ha...

#Tuberculosis prevention and care relies heavily on international donor funding in many settings. In our latest preprint, we examine the potential impact of reductions in international donor funding for #TB - by the US and by other major donor countries. 1/8

www.medrxiv.org/content/10.1...

Climate-driven migration and displacement and their potential impact on TB in Latin America gh.bmj.com/content/10/4... @cfmcquaid.bsky.social @reinhouben.bsky.social @lshtm-tbmod.bsky.social

New pre-print modelling impact of US funding cuts on HIV, #TB, MCH and family planning. We estimate impact of termination of US funding to NTPs via #USAID & The Global Fund may lead to 2.2 (1.5-2.9) million excess TB deaths between 2025 and 2040, reversing over a decade of progress.

bit.ly/4lowp18

Our latest pre-print led by @alexandra-richards.bsky.social shows that improving #TB treatment coverage among men to the level achieved among women could reduce morbidity and mortality in men, women, and children. Further evidence of the need for gender-responsive TB prevention and care!

Great to be able to finally get this work out, closing out my time with @lshtm-tbmod.bsky.social

As I've adjusted the code to using ggplot and added some extra features, here is the link to my GitHub with the code and some (hopefully) simple instructions.
github.com/alexandrasri...

If anyone gives this a go, I'd love to see other examples!

A year ago, I was tasked with creating a timeline for @lshtm-tbmod.bsky.social and we came across this amazing example of a way to keep track of a group with a long history.
We now have a record of our history going back to 2011, and I hope that this can stay alive and continuously updated as well!

Trump Is Ceding Ground to a Deadly Enemy, an essay by me adapted from my book Everything Is Tuberculosis.

www.theatlantic.com/health/archi...

PhD position (London, UK)
Quantify the effects of climate change on TB
with @cfmcquaid.bsky.social @reinhouben.bsky.social @laragosce.bsky.social
at @cmmid-lshtm.bsky.social @tb-lshtm.bsky.social @lshtm.bsky.social
More details: http://iddjobs.org/jobs/2253

Hot off the press! 🔥 Our new systematic review digs deep into #TB cluster randomised trials, exploring how contamination can influence results, and offers insights for improving trial design #TBSky #IDSky #MedSky doi-org.ez.lshtm.ac.uk/10.5588/ijtl...

The advert is now live here:
jobs.lshtm.ac.uk/EPH-EPED-202...

Until August 2027 we would be working on data analysis and modelling to try and untangle the dynamics of #AMR by age and sex exploring electronic health records 🧫📑👩‍💻. Get in touch if any questions!

I’m hiring! watch this space for a 2yr position on modelling and data analysis to determine how #AMR varies by age and sex @lshtm.bsky.social

Reducing #TB burden requires understanding local contexts. Our new preprint emphasizes the importance of considering social contact patterns for interventions like active case finding, infection prevention & control, & cluster trial design #TBsky #IDsky #GlobalHealth

www.medrxiv.org/content/10.1...

New preprint (with all pre-print caveats!) tinyurl.com/589ffhu4 on Mtb infection risk by sex & age.
Men are at higher risk of #tuberculosis v women- but unclear how much driven by higher infection vs progression to disease. We meta-analysed Mtb immunoreactivity surveys to find out more🧵 #tbsky

Our ASCENT modelling paper on Digital Adherence Technologies (DAT) for TB treatment is now out in BMJ Global Health gh.bmj.com/content/9/12... DATs may have limited epidemiological impact but can reduce costs and have important budgetary implications. @cfmcquaid.bsky.social @lshtm-tbmod.bsky.social