Andrew Mendiola
@andrewmendiola.bsky.social
1.5K followers 400 following 95 posts
Assistant Professor, UCSD School of Medicine We study brain Immunology and how innate immunity drives inflammation in multiple sclerosis and Alzheimer’s. Mendiolalab.com
Posts Media Videos Starter Packs
Pinned
andrewmendiola.bsky.social
Thrilled to share that I received the NoA for my first R01 “Mechanisms of pathogenic microglial populations in CNS inflammation”. Major milestone for the Lab. Extremely grateful for SS/SRO, PO and everyone else at NINDS for their continued support. Photo of my lab, wife and son, celebrating!
Reposted by Andrew Mendiola
jeremymberg.bsky.social
A show of bipartisan support for NIH. Basically flat except for ARPA-H.

The President’s budget proposal basically ignored (as it should have been).
ianlmorgan.bsky.social
House LHHC bill is out. Lots of hits to HHS, but the top line number for NIH is 1% decrease, mostly due to cuts ARPA-H. This seems like a huge rejection of the president's budget request.
democrats-appropriations.house.gov
andrewmendiola.bsky.social
Honored to receive an @alzassociation.bsky.social Research Grant for my project “Role of APOE4-driven microglial mitochondrial dysfunction”. Excited to advance our research on APOE4, neurovascular inflammation, and microglial metabolism in Alzheimer’s disease. Grateful to be #ALZFunded !!
Reposted by Andrew Mendiola
lozanzi.bsky.social
#InterferonPower! Thrilled for our latest work @cp-cell.bsky.social! With @danielboehmer.bsky.social, we dug into tons of papers & created what we hope will be a go-to resource for immunologists & non-immunologist about type I, II, III (& IV😉) #interferons! Free👉 authors.elsevier.com/a/1leKGL7PXu...
Reposted by Andrew Mendiola
danis1337.bsky.social
This is so frustrating. In 2018 I remember thinking how this paper would transform my work since we were already looking at mitophagy. I have cited this paper in 3 of my papers between 2018-2020 and probably every grant application. This guy won a 2021 breakthrough prize in part because of this work
RETRACTED ARTICLE: Parkin and PINK1 mitigate STING-induced inflammation
Reposted by Andrew Mendiola
andersshansen.bsky.social
I have
NIGMS R35, impact score 12
NIHGRI R21, 4th percentile
NHGRI R01, 7th percentile (co-I)
and it seems like none will be funded. 0/3.

PO (who has been very helpful) said "Unfortunately, I do not expect this application will be selected for funding in FY25."

😭
andrewmendiola.bsky.social
one of the best!
joann-trejo.bsky.social
Here you go..." Why strong mentorship was essential for my career success in science" JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors. www.nature.com/articles/d41...
Why strong mentorship was essential for my career success in science
JoAnn Trejo has turned mentoring into an evidence-based science, driven by her own exposure to inspiring mentors.
www.nature.com
andrewmendiola.bsky.social
Managed to track down some texas-style bbq in san diego. Gathered the lab to celebrate their accomplishments and keep building our amazing community!
Reposted by Andrew Mendiola
johannajoyce.bsky.social
The numbers of women in science falls substantially at the transition from postdoc to independent investigator/ PI

So what can we do to prevent this?

One initiative we now organise annually at #EACR is the highly successful 'Women in Leadership' workshop ⏬

#WomenInScience 🧪
@helloeacr.bsky.social
The EACR’s Women in Leadership workshop returns for 2025 - The Cancer Researcher
Ahead of the EACR 2025 Congress in Lisbon, Portugal, the EACR once again hosted its popular Women in Leadership Workshop on 16 June 2025. The event brought together 26 early-career female cancer resea...
magazine.eacr.org
Reposted by Andrew Mendiola
blekhman.bsky.social
200 days in, checking in on HHMI funding opportunities:

Freeman Hrabowski Scholars Program - not accepting applications

Gilliam Fellows Program - not accepting applications

Hanna H. Gray Fellows Program - not accepting applications

Investigator Program - not accepting applications
blekhman.bsky.social
This is not some small foundation -- HHMI has a $24 billion endowment. It is the world's 2nd richest biomedical research foundation.

If any funder can double down on their support for science right now, it's HHMI. But they are doing the opposite.
Reposted by Andrew Mendiola
kgandersen.bsky.social
Just to give the TL;DR on this one:

*The* main purpose of the EO is to move funding priorities and decisions away from experts and career professionals over to political appointees. With the ultimate power held by Vought / OMB.
andrewmendiola.bsky.social
Interested in keeping track
R01 first submission Oct 24 to NINDS (ESI/NI status)
SS April (Initially Feb)
Council May
1st JIT June (Council Rev completed status)
2nd JIT July (pending eRA status)
NoA August
*NINDS staff are amazing
andrewmendiola.bsky.social
Thrilled to share that I received the NoA for my first R01 “Mechanisms of pathogenic microglial populations in CNS inflammation”. Major milestone for the Lab. Extremely grateful for SS/SRO, PO and everyone else at NINDS for their continued support. Photo of my lab, wife and son, celebrating!
Reposted by Andrew Mendiola
raflynn5.bsky.social
RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...
Reposted by Andrew Mendiola
barrlab.bsky.social
We need a new microscope objective. A $1.6k tariff for something that you can hold in your hand and that is only manufactured in Germany
Quote for a 63x objective. The objective is $12,784. The tariff is $1,661.92 Zeiss 63x objective
andrewmendiola.bsky.social
www.sciencedirect.com/science/arti... Great review on "Alzheimer’s disease and vascular biology – A focus on the procoagulant state"