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Evelina Tutucci

@anilevetu.bsky.social

3.1K followers 1.4K following 80 posts

Assistant professor at Vrije University Amsterdam We study spatiotemporal control of gene expression. We develop tools to visualize and quantify single mRNAs in fungi and bacteria #RNA #single-molecule #imaging-analysis 🍄🦠🇮🇹➡️🇨🇭➡️🇺🇸➡️ 🇳🇱 www.tutuccilab.com

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Evelina Tutucci @anilevetu.bsky.social · Feb 26

It's out!
Beautiful work led by Loreto Oyarte Gálvez & @cbisot.bsky.social!
Do you want to learn more about how Mycorrhizal fungi extraordinary networks form and function? Read the open-access publication! Link below 👇

Society for the Protection of Underground Networks (SPUN) @spun.earth · Feb 26

Our newest research on plant-fungal trade published today in @nature.com.

The work, led by scientists from Vrije Universiteit, Princeton University, SPUN & AMOLF combines robotics, mycology & biophysics to reveal underground supply-chain dynamics.

Open access:
www.nature.com/articles/s41...

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Reposted by Evelina Tutucci

KOJAMF🤘🖤🤘 @kojamf.bsky.social · 3d

Dr. Jane Goodall filmed an interview with Netflix in March 2025 that she understood would only be released after her death.

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Reposted by Evelina Tutucci

Joachim Goedhart @joachimgoedhart.bsky.social · 8d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Evelina Tutucci @anilevetu.bsky.social · 10d

Collective homeostasis of condensation-prone proteins via their mRNAs | Nature share.google/zkKumKefL83G...

Collective homeostasis of condensation-prone proteins via their mRNAs - Nature

The authors discover a homeostatic process termed interstasis, in which an increased concentration of proteins within RNA–protein condensates induces the sequestration of their own mRNAs.

share.google

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Reposted by Evelina Tutucci

Ulrich Hohmann @hohmannulrich.bsky.social · 16d

How are RNAs sorted for export vs. degradation in the nucleus? In collaboration with @heick.bsky.social’s lab we (@clemensplaschka.bsky.social and @juliusbrennecke.bsky.social labs) discovered a direct mechanistic link between the export and decay machineries: www.biorxiv.org/content/10.1... (1/x)

Molecular basis of polyadenylated RNA fate determination in the nucleus

Eukaryotic genomes generate a plethora of polyadenylated (pA+) RNAs[1][1],[2][2], that are packaged into ribonucleoprotein particles (RNPs). To ensure faithful gene expression, functional pA+ RNPs, in...

www.biorxiv.org

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Evelina Tutucci @anilevetu.bsky.social · 15d

I say Wow back :) thank you for the kind words!
We will need some clonings and testing...it's a great internship project... I will let you know what we see!

Reposted by Evelina Tutucci

John Ngo @johntngo.bsky.social · 16d

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

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Evelina Tutucci @anilevetu.bsky.social · 15d

Beautiful RNA movies! Looking forward to trying the constructs in yeast!

Reposted by Evelina Tutucci

Dr Zeinab Rekad 🔬🧬🧪 @zeinabrekad.bsky.social · 16d

#RNAsky 🤩🤩🤩

John Ngo @johntngo.bsky.social · 16d

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Reposted by Evelina Tutucci

Nature Methods @natmethods.nature.com · 21d

A new Perspective discusses the challenges of sharing annotated image datasets and offers advice for improving bioimage annotation and reuse, particularly for AI applications.

www.nature.com/articles/s41...

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Reposted by Evelina Tutucci

Brian Umberger @brianumberger.bsky.social · Aug 28

Please repost!

We have an open rank, tenure-line faculty position in biomechanics in the School of Kinesiology at the University of Michigan Ann Arbor. At U-M we have great colleagues, exceptional resources, and biomechanics can be found all across the campus. #BiomechSky

Tenure-track Faculty Position in Biomechanics (Open Rank), University of Michigan, Ann Arbor, MI, USA - Biomch-L

The School of Kinesiology (http://kines.umich.edu) at the University of Michigan invites applications and nominations for a tenure-track faculty position at the level of Assistant Professor, Associate...

biomch-l.isbweb.org

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Reposted by Evelina Tutucci

Jutras Lab @jutraslab.bsky.social · Sep 6

Our lab manager search is live! 👇
Please like and re-post
#MicroSky

www.linkedin.com/jobs/view/re...

Northwestern University hiring Research Lab Manager 1 - Jutras Lab in Chicago, IL | LinkedIn

Posted 8:17:05 PM. Department: MED-Microbiology-ImmunologySalary/Grade: EXS/6Target hiring range for this position…See this and similar jobs on LinkedIn.

www.linkedin.com

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Evelina Tutucci @anilevetu.bsky.social · Sep 5

A very interesting initiative!

Amsterdam library exhibits books banned in Trump's US - DutchNews.nl share.google/oBs3Hv9MZfjL...

DutchNews.nl

DutchNews.nl is the leading provider of quality Dutch news in English for an international audience.

DutchNews.nl

Reposted by Evelina Tutucci

Harry Low’s Lab @lowlab.bsky.social · Nov 11

Now out in NSMB for those who missed our biorxiv back in 2023.. bacterial ESCRT-III-like #Vipp1 forms dynamic spiral filaments on membrane! Spirals are springs that drive 3D ring formation in the spiral centre! 😵‍💫 wonderful collaboration with Adai Colom’s lab and @rouxlab.bsky.social

rdcu.be/dZSPQ

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Reposted by Evelina Tutucci

Trcek Lab @trceklab.bsky.social · Aug 30

New paper from the Trcek lab, with Siran Tian as the lead author - congratulations Siran!: www.nature.com/articles/s41...

Controlling intermolecular base pairing in Drosophila germ granules by mRNA folding and its implications in fly development - Nature Communications

Tian et al. show that RNA folding limits extensive base pairing among mRNAs in Drosophila germ granules. Instead, mRNAs interact via scattered bases exposed on the surface of folded RNAs, which may pr...

www.nature.com

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Evelina Tutucci @anilevetu.bsky.social · Aug 31

#RNAbiology #RNAlocalization #LocalizedTransaltion
www.cell.com/cell/fulltex...

Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation

Development of LOV-domain-controlled ligase for translation localization (LOCL-TL), an optogenetic approach for monitoring translation with codon resolution at any defined subcellular location under p...

www.cell.com

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Reposted by Evelina Tutucci

Amelia Cervera 🍉 @ameliacervera.bsky.social · Aug 31

#TEsky #RNAsky #RNAbiology

Abby Buchwalter @abbybuch.bsky.social · Jul 22

Another paper bluetorial! Today: how does the spatial location of genes influence their function? (1/n) www.nature.com/articles/s41...

The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate - Nature Cell Biology

Marin et al. report the role of lamin proteins and the lamin B receptor (LBR) in chromatin positioning at the nuclear periphery. Knockout of all lamins and LBR in mouse embryonic stem cells leads to h...

www.nature.com

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Evelina Tutucci @anilevetu.bsky.social · Aug 26

Beatiful article @tobykiers.bsky.social !
Source: NPR
search.app/tP7Ep

How plants and fungi trade resources without a brain

Fungi and plants have something to teach humans about global trade and cooperation

search.app

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Reposted by Evelina Tutucci

Ahmad Jomaa @jomaalab.bsky.social · Aug 26

Want to know how lipidation of some nascent chains takes place by NMT2-- Check our latest work on how NAC couples Protein Synthesis with Nascent Polypeptide Myristoylation on the Ribosome out today @embojournal.org‬: www.embopress.org/doi/full/10....

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Reposted by Evelina Tutucci

Vivek Mutalik @vivekmutalik.bsky.social · Aug 26

#microsky ##synbiosky
Database of sensors

Figure from a research paper explaining a database of protein sensors

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Evelina Tutucci @anilevetu.bsky.social · Aug 22

A time-resolved framework for the recruitment of mRNP processing and assembly factors to a site of transcription.

Great work by the Montpetit lab!
#RNAbiology #RNAprocessing #mRNP
doi.org/10.1093/nar/...

Validate User

doi.org

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Reposted by Evelina Tutucci

Richard Lenski @relenski.bsky.social · Aug 12

Excited to share new #program, STEPS, which can simulate #dynamics of the E. coli Long-Term Evolution Experiment (#LTEE) or other microbes in serial transfer regime.

telliamedrevisited.wordpress.com/2025/08/12/s...

STEPS developed by @devinmlake.bsky.social, Zachary Matson, Minako Izutsu, and me.

STEPS To It

Announcing a new program, called STEPS, to simulate the dynamics of evolving microbial populations.

telliamedrevisited.wordpress.com

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Evelina Tutucci @anilevetu.bsky.social · Aug 10

Great to hear! No, luckily I didn't get sick and I managed to enjoy some holidays. Talk to you soon!

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Evelina Tutucci @anilevetu.bsky.social · Aug 10

pubmed.ncbi.nlm.nih.gov/40773237/

O-GlcNAc modulation of nuclear pore complexes orchestrates mRNA export efficiency - PubMed

Efficient gene expression depends on the tightly regulated export of messenger RNA (mRNA) through nuclear pore complexes (NPCs), which are densely modified by O-linked N-acetylglucosamine (O-GlcNAc). ...

pubmed.ncbi.nlm.nih.gov

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Evelina Tutucci @anilevetu.bsky.social · Aug 7

Take good care! There is no need to do an evolution experiment with French bugs, we can ship them to you :)

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Reposted by Evelina Tutucci

Nature Methods @natmethods.nature.com · Aug 7

A paper from the JUMP Cell Painting Consortium presents image-based phenotypic profiles for 75% of the protein coding genome of human U-2 OS cells, offering a valuable resource for exploring gene relationships. @shantanu-singh.cc @drannecarpenter.bsky.social

www.nature.com/articles/s41...

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