Leonard Asan
@asankleo.bsky.social
Affective Neuroscience | Doctoral candidate at Uni Med Center Hamburg as part of RTG 2753 Emotional Learning and Memory | Investigating opioidergic mechanisms of motivation-induced pain modulation
Reposted by Leonard Asan
A 2024 study found that ants best humans at tests of collective intelligence.
Learn more: https://scim.ag/42nMvQJ #ScienceMagArchives
Learn more: https://scim.ag/42nMvQJ #ScienceMagArchives
December 26, 2025 at 10:10 PM
A 2024 study found that ants best humans at tests of collective intelligence.
Learn more: https://scim.ag/42nMvQJ #ScienceMagArchives
Learn more: https://scim.ag/42nMvQJ #ScienceMagArchives
Reposted by Leonard Asan
Excited to share that the main work of my PhD has been published!
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
Controllability changes pain perception by increasing the precision of expectations
Nature Communications - Control over pain changes how intense it is perceived. Here, the authors show that this effect results from increased expectation precision with control, which changes...
rdcu.be
November 22, 2025 at 1:50 PM
Excited to share that the main work of my PhD has been published!
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
We found that having control over pain makes expectations more precise, and changes pain perception. This is accompanied by activation changes in the PAG, SMA and ACC.
You can read the full version of the paper here: rdcu.be/eQy6X
Reposted by Leonard Asan
Criminal risk behavior can be an early sign of dementia - raising important clinical and legal questions.
Excited to share the findings from our meta-analysis: www.nature.com/articles/s41...
Excited to share the findings from our meta-analysis: www.nature.com/articles/s41...
Criminal minds in #dementia: Broad meta-analysis by Matthias Schroeter & Lena Szabo in @nature.com including 236,360 persons. They found that larger atrophy in the brain is linked to criminal behavior in frontotemporal dementia, suggesting a loss of normal behavioral restraints. tinyurl.com/4dt6jd7s
September 3, 2025 at 2:23 PM
Criminal risk behavior can be an early sign of dementia - raising important clinical and legal questions.
Excited to share the findings from our meta-analysis: www.nature.com/articles/s41...
Excited to share the findings from our meta-analysis: www.nature.com/articles/s41...
Reposted by Leonard Asan
I am thrilled about this new preprint of ours! Using 7T fMRI of the spinal cord we uncover two different spinal response components – phasic and tonic heat responses – that map differentially onto superficial and deep layers of the dorsal horn! 🔥Long thread upcoming!🧵 www.biorxiv.org/content/10.1...
Ultra-high-field fMRI reveals layer-specific responses in the human spinal cord
Developments in functional magnetic resonance imaging (fMRI) at ultra-high field (UHF) now allow for insights into human brain function at mesoscopic scale. However, similar progress has not been achi...
www.biorxiv.org
August 26, 2025 at 8:10 AM
I am thrilled about this new preprint of ours! Using 7T fMRI of the spinal cord we uncover two different spinal response components – phasic and tonic heat responses – that map differentially onto superficial and deep layers of the dorsal horn! 🔥Long thread upcoming!🧵 www.biorxiv.org/content/10.1...
Reposted by Leonard Asan
Exercise can reduce pain. But you don’t have to just work out harder to feel the benefit. New research suggests that fitness level and sex may play a bigger role than exercise intensity in how we experience exercise-induced pain relief.
buff.ly/6oo87SW
buff.ly/6oo87SW
August 20, 2025 at 10:01 AM
Exercise can reduce pain. But you don’t have to just work out harder to feel the benefit. New research suggests that fitness level and sex may play a bigger role than exercise intensity in how we experience exercise-induced pain relief.
buff.ly/6oo87SW
buff.ly/6oo87SW
Reposted by Leonard Asan
Major news!
Exhaustive metaanalysis (N=2706) finding that endogenous opioids play a MINOR role in human pain regulation:
Consistent with 0.3 on 11-point VAS
By @isabellmeier.bsky.social @martintrostheim.bsky.social @marieeikemo.bsky.social @loseth.bsky.social et al
Thread 👇
osf.io/preprints/os...
Exhaustive metaanalysis (N=2706) finding that endogenous opioids play a MINOR role in human pain regulation:
Consistent with 0.3 on 11-point VAS
By @isabellmeier.bsky.social @martintrostheim.bsky.social @marieeikemo.bsky.social @loseth.bsky.social et al
Thread 👇
osf.io/preprints/os...
OSF
osf.io
August 11, 2025 at 2:35 PM
Major news!
Exhaustive metaanalysis (N=2706) finding that endogenous opioids play a MINOR role in human pain regulation:
Consistent with 0.3 on 11-point VAS
By @isabellmeier.bsky.social @martintrostheim.bsky.social @marieeikemo.bsky.social @loseth.bsky.social et al
Thread 👇
osf.io/preprints/os...
Exhaustive metaanalysis (N=2706) finding that endogenous opioids play a MINOR role in human pain regulation:
Consistent with 0.3 on 11-point VAS
By @isabellmeier.bsky.social @martintrostheim.bsky.social @marieeikemo.bsky.social @loseth.bsky.social et al
Thread 👇
osf.io/preprints/os...
Reposted by Leonard Asan
May et al. find that the relationship between peak alpha frequency and pain does not generalize to brief experimental pain calling for a systematic exploration across different pain types. Learn more in #PAIN bit.ly/3Hmxszm
August 12, 2025 at 12:00 PM
May et al. find that the relationship between peak alpha frequency and pain does not generalize to brief experimental pain calling for a systematic exploration across different pain types. Learn more in #PAIN bit.ly/3Hmxszm
Reposted by Leonard Asan
Hilft künstliche Intelligenz bei der #Demenz - Diagnose? Simon Hofmann @mpicbs.bsky.social erklärt im neuen #AchMensch Podcast, wie sich Ärzte in Zukunft durch #KI unterstützen lassen können und woran der Einsatz bislang scheitert detektor.fm/wissen/ach-m... #Medizin #Gehirn @detektorfm.bsky.social
Kann KI in der Medizin Leben retten, Simon Hofmann?
Der Neurowissenschaftler Simon Hofmann untersucht, wie künstliche Intelligenz in der Medizin zum Einsatz kommen kann.
detektor.fm
July 9, 2025 at 1:26 PM
Hilft künstliche Intelligenz bei der #Demenz - Diagnose? Simon Hofmann @mpicbs.bsky.social erklärt im neuen #AchMensch Podcast, wie sich Ärzte in Zukunft durch #KI unterstützen lassen können und woran der Einsatz bislang scheitert detektor.fm/wissen/ach-m... #Medizin #Gehirn @detektorfm.bsky.social
important, please give this a read!
Serious concerns about a new cortical biomarker for pain sensitivity
jamanetwork.com/journals/jam...
We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results.
👇 1/13
jamanetwork.com/journals/jam...
We (with @tspisak.bsky.social, @christianbuchel.bsky.social) published a commentary on Chowdhury, Bi et al. (2025, JAMA Neurology) raising serious concerns about their reported results.
👇 1/13
Concern About Predictive Performance of a Pain Sensitivity Biomarker
To the Editor Chowdhury et al1 evaluated a biomarker for pain sensitivity, combining peak alpha frequency and corticomotor excitability. The authors report outstanding performance (validation set area...
jamanetwork.com
July 22, 2025 at 3:27 PM
important, please give this a read!
Reposted by Leonard Asan
Hubschmid et al. find that monetary rewards increase sensory signal strength leading to enhanced pain discrimination. Mechanistically, this process seems to be driven by learning from positive prediction errors. Learn more in #PAIN bit.ly/4lWzNjb
July 21, 2025 at 12:00 PM
Hubschmid et al. find that monetary rewards increase sensory signal strength leading to enhanced pain discrimination. Mechanistically, this process seems to be driven by learning from positive prediction errors. Learn more in #PAIN bit.ly/4lWzNjb