@azwildcats.bsky.social
Reposted
8yrs ago, if someone said “black lives matter” to me, I would’ve instantly pounced with “ALL lives matter.” Today, when someone says “black lives matter,” I respond with “you’re right, black lives DO matter.” What changed? Me. I listened. And learned.👇 open.substack.com/pub/socialco...
My Personal Reckoning on Race
America can do so much better
open.substack.com
February 14, 2026 at 4:57 PM
8yrs ago, if someone said “black lives matter” to me, I would’ve instantly pounced with “ALL lives matter.” Today, when someone says “black lives matter,” I respond with “you’re right, black lives DO matter.” What changed? Me. I listened. And learned.👇 open.substack.com/pub/socialco...
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Great sitting down with Brian Tyler Cohen to talk about everything from the courage we saw in Minnesota, to how Democrats can be true to our values and get stuff done, to how we’re building a community of changemakers at the Obama Foundation. youtube.com/watch?v=uI-hgSE5QIw
February 14, 2026 at 8:42 PM
Great sitting down with Brian Tyler Cohen to talk about everything from the courage we saw in Minnesota, to how Democrats can be true to our values and get stuff done, to how we’re building a community of changemakers at the Obama Foundation. youtube.com/watch?v=uI-hgSE5QIw
Good morning. The President of the United States was in the middle of the most serious child sex trafficking ring of the last quarter century.
He is referenced not a dozen times in the case files. Not 100 times. Not 1,000 times. He’s referenced 38,000 times.
He is referenced not a dozen times in the case files. Not 100 times. Not 1,000 times. He’s referenced 38,000 times.
February 9, 2026 at 1:40 AM
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Enjoy the Super Bowl. Enjoy Bad Bunny. Here are the heroes of the week, the resisters, the defenders of democracy.👇 open.substack.com/pub/socialco...
The Real Heroes of the Super Bowl
The Social Contract Weekly Wrap
open.substack.com
February 9, 2026 at 1:25 AM
Enjoy the Super Bowl. Enjoy Bad Bunny. Here are the heroes of the week, the resisters, the defenders of democracy.👇 open.substack.com/pub/socialco...
Reposted
A massive new voter suppression bill could disenfranchise 21 million Americans before the midterms.
The GOP-led campaign to create barriers to voting follows a series of alarming White House statements telegraphing its intent to interfere with the 2026 midterm elections.
The GOP-led campaign to create barriers to voting follows a series of alarming White House statements telegraphing its intent to interfere with the 2026 midterm elections.
GOP fast tracks monster voter suppression bill that could disenfranchise millions by requiring proof of citizenship at polls
In the past few weeks, passing the legislation has been a unifying rally cry for Republicans, a welcome distraction from the party’s cratering public opinion polls.
www.democracydocket.com
February 9, 2026 at 1:30 AM
A massive new voter suppression bill could disenfranchise 21 million Americans before the midterms.
The GOP-led campaign to create barriers to voting follows a series of alarming White House statements telegraphing its intent to interfere with the 2026 midterm elections.
The GOP-led campaign to create barriers to voting follows a series of alarming White House statements telegraphing its intent to interfere with the 2026 midterm elections.
Reposted
BREAKING: Massive Crowds of Anti-ICE protesters in Minneapolis, Minnesota as we speak. The tide is turning. America is Fed Up.
Americans should be fighting back against what is happening in this country. Having masked, secret police shooting people, breaking into homes and cars, is NOT normal.
Americans should be fighting back against what is happening in this country. Having masked, secret police shooting people, breaking into homes and cars, is NOT normal.
January 10, 2026 at 8:23 PM
BREAKING: Massive Crowds of Anti-ICE protesters in Minneapolis, Minnesota as we speak. The tide is turning. America is Fed Up.
Americans should be fighting back against what is happening in this country. Having masked, secret police shooting people, breaking into homes and cars, is NOT normal.
Americans should be fighting back against what is happening in this country. Having masked, secret police shooting people, breaking into homes and cars, is NOT normal.
Reposted
After the House refused to display it, the Senate unanimously agreed to hang a plaque honoring the officers who protected the Capitol on Jan. 6. It only took five years. www.nbcnews.com/politics/con...
Senate votes to display Jan. 6 plaque after House GOP refuses to hang it at Capitol
The office of House Speaker Mike Johnson, R-La., has argued that the federal law requiring the plaque's display was "not implementable."
www.nbcnews.com
January 9, 2026 at 7:58 AM
After the House refused to display it, the Senate unanimously agreed to hang a plaque honoring the officers who protected the Capitol on Jan. 6. It only took five years. www.nbcnews.com/politics/con...
Reposted
Cartoon by @bagleycartoons.bsky.social.
January 9, 2026 at 2:45 PM
Cartoon by @bagleycartoons.bsky.social.
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We can fund health care and keep the government running, or we can shut everything down to raise prices on people.
To me, that’s a pretty easy choice.
To me, that’s a pretty easy choice.
October 4, 2025 at 3:47 PM
We can fund health care and keep the government running, or we can shut everything down to raise prices on people.
To me, that’s a pretty easy choice.
To me, that’s a pretty easy choice.
Reposted
Phase 1b trial: BL-B01D1, an EGFR-HER3 bispecific ADC with a topoisomerase I inhibitor, shows promising efficacy/safety in 82 advanced ESCC patients. PMID:40640393, Nat Med 2025, @NatureMedicine https://doi.org/10.1038/s41591-025-03792-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
A bispecific antibody–drug conjugate targeting EGFR and HER3 in metastatic esophageal squamous cell carcinoma: a phase 1b trial | Nature Medicine
Research on patients with advanced esophageal squamous cell carcinoma (ESCC) who have progressed on immunotherapy remains limited. BL-B01D1 is a first-in-class antibody–drug conjugate consisting of an EGFR–HER3 bispecific antibody bound to a topoisomerase I inhibitor (Ed-04) payload via a cleavable linker. Here, we present safety and efficacy data from a phase 1 study of BL-B01D1, in 82 patients previously treated for ESCC. The primary endpoint was the recommended phase 2 dose. Administered doses were 2.0 (n = 22) and 2.5 (n = 60) mg kg−1 D1D8 infusion every 3 weeks (Q3W). The confirmed objective response rate (cORR) was 29.3% (24 of 82) in all patients and 32.9% (24 of 73) among evaluable patients. For patients dosed at 2.5 mg kg−1, cORR was 39.6% (21 of 53) and disease control rate was 79.2% (42 of 53). In the 2.0 mg kg−1 group, cORR was 15.0% (3 of 20), and the disease control rate was 50.0% (10 of 20). The phase 2 dose was established at 2.5 mg kg−1 D1D8 Q3W. The incidence of G3 tr
doi.org
August 29, 2025 at 4:10 AM
Phase 1b trial: BL-B01D1, an EGFR-HER3 bispecific ADC with a topoisomerase I inhibitor, shows promising efficacy/safety in 82 advanced ESCC patients. PMID:40640393, Nat Med 2025, @NatureMedicine https://doi.org/10.1038/s41591-025-03792-7 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
Reposted
In a rare public outburst on the Senate floor Tuesday, New Jersey Sen. Cory Booker took his Democratic colleagues to task, declaring his party “needs a wake-up call!”
Sen. Cory Booker in angry outburst says 'complicit' Democrats need a 'wake-up call'
In a rare public outburst on the Senate floor Tuesday, New Jersey Sen. Cory Booker took his Democratic colleagues to task, saying the party “needs a wake up call!”
apnews.com
July 30, 2025 at 3:09 AM
In a rare public outburst on the Senate floor Tuesday, New Jersey Sen. Cory Booker took his Democratic colleagues to task, declaring his party “needs a wake-up call!”
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Reaching To Obstruct The Epstein Case https://twp.ai/4ipx6y
crooksandliars.com
Reaching To Obstruct The Epstein Case | Crooks and Liars
twp.ai
July 30, 2025 at 3:12 AM
Reaching To Obstruct The Epstein Case https://twp.ai/4ipx6y
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The confirmation of Emil Bove to the 3rd Circuit is a direct assault on the integrity of our justice system.
A former Trump lawyer, Bove ordered a 15-year DOJ veteran to lie to a federal judge — then helped fire him for refusing.
Now he’s a judge. Corruption in action.
A former Trump lawyer, Bove ordered a 15-year DOJ veteran to lie to a federal judge — then helped fire him for refusing.
Now he’s a judge. Corruption in action.
Emil Bove confirmation is a direct assault on the integrity of our justice system
YouTube video by Senator Chris Van Hollen
youtu.be
July 30, 2025 at 3:13 AM
The confirmation of Emil Bove to the 3rd Circuit is a direct assault on the integrity of our justice system.
A former Trump lawyer, Bove ordered a 15-year DOJ veteran to lie to a federal judge — then helped fire him for refusing.
Now he’s a judge. Corruption in action.
A former Trump lawyer, Bove ordered a 15-year DOJ veteran to lie to a federal judge — then helped fire him for refusing.
Now he’s a judge. Corruption in action.
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8 things you need to know about the new “Nimbus” and “Stratus” COVID-19 variants.
"The NB.1.8.1 and XFG sub-variants are rapidly spreading and competing for global dominance."
www.gavi.org/vaccineswork...
"The NB.1.8.1 and XFG sub-variants are rapidly spreading and competing for global dominance."
www.gavi.org/vaccineswork...
Eight things you need to know about the new “Nimbus” and “Stratus” COVID-19 variants
The NB.1.8.1 and XFG sub-variants are rapidly spreading and competing for global dominance.
www.gavi.org
June 21, 2025 at 11:13 PM
8 things you need to know about the new “Nimbus” and “Stratus” COVID-19 variants.
"The NB.1.8.1 and XFG sub-variants are rapidly spreading and competing for global dominance."
www.gavi.org/vaccineswork...
"The NB.1.8.1 and XFG sub-variants are rapidly spreading and competing for global dominance."
www.gavi.org/vaccineswork...
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We’re dealing with criminals, from the top to the bottom.
Not “ICE” changing license plates in a back lot.
They wouldn’t do that, would they? Maybe the authorities should look into this.
They wouldn’t do that, would they? Maybe the authorities should look into this.
June 22, 2025 at 3:30 PM
We’re dealing with criminals, from the top to the bottom.
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Millions of people who use the food assistance program SNAP are facing changes: on what food they can buy, how much money they'll receive or even if they'll still qualify for the program. https://n.pr/3ZAftvr
This mother relies on SNAP to help feed her kids. Now, she's bracing for cuts
Millions of people who use the food assistance program SNAP are facing changes: on what food they can buy, how much money they'll receive or even if they'll still qualify for the program.
n.pr
June 16, 2025 at 1:38 PM
Millions of people who use the food assistance program SNAP are facing changes: on what food they can buy, how much money they'll receive or even if they'll still qualify for the program. https://n.pr/3ZAftvr
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Let me be clear: Political violence has no place in our nation. Elected officials must be safe to do their job on behalf of the people. The hate and division that dominate our political discourse must end.
June 14, 2025 at 6:14 PM
Let me be clear: Political violence has no place in our nation. Elected officials must be safe to do their job on behalf of the people. The hate and division that dominate our political discourse must end.
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ASSASSINATED not just killed. Say it. Talk about the reality of this.
June 15, 2025 at 1:01 AM
ASSASSINATED not just killed. Say it. Talk about the reality of this.
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Minnesota Rep. Melissa Hortman was a friend who worked with Gabby to stop gun violence. We’re thinking of her children, who've now lost both their parents, and we’re praying for Sen. Hoffman and his wife, who are still fighting for their lives.
Stay strong.
Stay strong.
June 15, 2025 at 1:00 AM
Minnesota Rep. Melissa Hortman was a friend who worked with Gabby to stop gun violence. We’re thinking of her children, who've now lost both their parents, and we’re praying for Sen. Hoffman and his wife, who are still fighting for their lives.
Stay strong.
Stay strong.
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"Mobilizing military forces into cities is going to be seen as an overreach, and it's going to be now met with peaceful, boisterous moms, dads, grandmas. kids and their dogs and families showing up, saying, 'we're not going to put up with this authoritarianism..."
www.usatoday.com/story/news/p...
www.usatoday.com/story/news/p...
Planned ‘No Kings’ protests grow in number after LA militarization: What organizers expect
'The numbers have skyrocketed': protest organizers expect massive crowds nationwide on June 14, including up to 250,000 in Los Angeles.
www.usatoday.com
June 13, 2025 at 4:01 AM
"Mobilizing military forces into cities is going to be seen as an overreach, and it's going to be now met with peaceful, boisterous moms, dads, grandmas. kids and their dogs and families showing up, saying, 'we're not going to put up with this authoritarianism..."
www.usatoday.com/story/news/p...
www.usatoday.com/story/news/p...