Lightnews — Scholar-powered news

Reposted by Vijay G. Sankaran

Dana-Farber Cancer Institute @danafarber.bsky.social · 23h

We are proud to announce that U.S. News & World Report has recognized Dana-Farber/Boston Children's (@bostonchildrens.bsky.social) Cancer and Blood Disorders Center as the #3 pediatric cancer program in the nation in its 2025-26 Best Children's Hospitals report.

Learn more: bit.ly/4o7ApUc

U.S. News & World Report – Best Children's Hospitals – Cancer

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Reposted by Vijay G. Sankaran

The New York Times @nytimes.com · 2d

Breaking News: The Nobel Prize in Physiology or Medicine was awarded to Mary Brunkow, Fred Ramsdell and Shimon Sakaguchi for their work on immune systems.

Nobel Prize in Physiology or Medicine Is Awarded for Work in Peripheral Immune Tolerance

Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi were awarded the prize on Monday.

nyti.ms

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Vijay G. Sankaran @bloodgenes.bsky.social · 8d

www.nih.gov/news-events/...

Secretary Kennedy Swears in Dr. Anthony Letai as Director of the National Cancer Institute

Dr. Letai will serve as NCI’s 18th director.

www.nih.gov

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Keystone Symposia @keystonesymposia.bsky.social · 13d

Abstracts & scholarship apps for #KSHemato26 are due Oct 29—but @beaudinlab.bsky.social explains why you should submit early! 🎥 youtu.be/FcO6D87EC_Q

Join us Feb 23–26, 2026 in Keystone, CO 👉 keysym.us/KSHemato26

@bloodgenes.bsky.social #hematopoiesis #bonemarrow #hematopoieticstemcells

KSQA: Dr. Anna Beaudin (Hematopoiesis)

YouTube video by KeystoneSymposia

youtu.be

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Reposted by Vijay G. Sankaran

Til Steinicke @til-steinicke.bsky.social · 15d

Epigenetic diagnosis of acute leukemia within two hours from sample receipt 🚀

Very happy to share the results of a great collaboration between @hovestadt.bsky.social and Griffin Labs, I co-led with @sbenfatto.bsky.social, published today in @natgenet.nature.com
📄 www.nature.com/articles/s41...
🧵1/n

Rapid epigenomic classification of acute leukemia - Nature Genetics

The authors present a molecular classification of acute leukemia using 5-methylcytosine signatures, together with a neural network-based classifier for clinical use.

www.nature.com

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Reposted by Vijay G. Sankaran

Yun S. Song @yun-s-song.bsky.social · 16d

We are excited to share GPN-Star, a cost-effective, biologically grounded genomic language modeling framework that achieves state-of-the-art performance across a wide range of variant effect prediction tasks relevant to human genetics.
www.biorxiv.org/content/10.1...
(1/n)

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Vijay G. Sankaran @bloodgenes.bsky.social · 16d

Such an important article on the challenges facing our ability to develop 🧬 gene therapies for genetic 🩸 disorders:

www.nytimes.com/2025/09/22/h...

These Patients Got the Cure. Then It Went Away.

www.nytimes.com

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American Society of Pediatric Hematology/Oncology @aspho-hq.bsky.social · 17d

Today is World Marrow Donor Day! We hope you will join us today in thanking the selfless individuals who register and donate stem cells to save the lives of patients in need. #WMDD25 #PedsHemeOnc #PHODocs #hematology

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Vijay G. Sankaran @bloodgenes.bsky.social · 26d

Congratulations, @obenaufa.bsky.social!!!

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Vijay G. Sankaran @bloodgenes.bsky.social · 26d

Congratulations, @trevorgraham.bsky.social and team!!!

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Trevor Graham @trevorgraham.bsky.social · 28d

Studying cancer evolution needs multi-region or single cell seq for phylogenetics, right? Amazingly (I think!) we found single-sample bulk methylation suffices, via analysis of "fluctuating methylation". In @nature.com today led by brilliant @calumgabbutt.bsky.social www.nature.com/articles/s41...

Fluctuating DNA methylation tracks cancer evolution at clinical scale - Nature

Cancer evolutionary dynamics are quantitatively inferred using a method, EVOFLUx, applied to fluctuating DNA methylation.

www.nature.com

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Vijay G. Sankaran @bloodgenes.bsky.social · 26d

Congratulations to this amazing group who received the @laskerfdn.bsky.social awards!!!

www.nytimes.com/2025/09/11/h...

Major Medical Prizes Given to Cell Biology and Cystic Fibrosis Pioneers

www.nytimes.com

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Vijay G. Sankaran @bloodgenes.bsky.social · 29d

www.nytimes.com/2025/09/08/o...

Opinion | We Are Watching a Scientific Superpower Destroy Itself

www.nytimes.com

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Reposted by Vijay G. Sankaran

Seth Shipman @seth-shipman.bsky.social · 29d

Check out MitoScribe in our new preprint led by Linhan Wang: www.biorxiv.org/content/10.1...

It's an analog molecular recorder that uses neutral base edits to the mitochondrial genome to store information about historical signaling in a cell. Single cell resolution at scale (see next post)!

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Vijay G. Sankaran @bloodgenes.bsky.social · Sep 7

RIP David. So fortunate to have had the opportunity to interact with David and to have worked with many of his trainees, including his last graduate student.
www.nytimes.com/2025/09/07/s...

David Baltimore, Nobel-Winning Molecular Biologist, Dies at 87

www.nytimes.com

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Reposted by Vijay G. Sankaran

Peter van Galen @vangalenlab.bsky.social · Sep 6

Excited to share our latest work on blood aging! To find out why the blood system changes as people age, we started at the source: hematopoietic stem cells (HSCs) #hemesky 🩸🧬 doi.org/10.1101/2025... 🧵 1/5

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Vijay G. Sankaran @bloodgenes.bsky.social · Sep 5

Congratulations, @olzmannlab.bsky.social!!! So incredibly well deserved!

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Molly Przeworski @mollyprz.bsky.social · Sep 2

In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social ‬ & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n
www.biorxiv.org/cgi/content/...

Collateral mutagenesis funnels multiple sources of DNA damage into a ubiquitous mutational signature

Mutations reflect the net effects of myriad types of damage, replication errors, and repair mechanisms, and thus are expected to differ across cell types with distinct exposures to mutagens, division ...

www.biorxiv.org

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Vijay G. Sankaran @bloodgenes.bsky.social · Aug 30

Congratulations, @mads100tist.bsky.social!!!

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Eric Topol @erictopol.bsky.social · Aug 28

Your DNA sequence reveals a rare mutation. Will you get the disease, i.e. penetrance? A new study using machine learning predicts this across 10 common diseases, 1,600 genomic variants
New @science.org
science.org/doi/10.1126/...

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Vijay G. Sankaran @bloodgenes.bsky.social · Aug 27

Cool! Congratulations!!!

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Vijay G. Sankaran @bloodgenes.bsky.social · Aug 27

Congratulations, @richardsever.bsky.social!!!

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Vijay G. Sankaran @bloodgenes.bsky.social · Aug 22

Congratulations, @cherylkeller.bsky.social!!! Such wonderful news!

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Vijay G. Sankaran @bloodgenes.bsky.social · Aug 21

😢 So sorry, Anders!

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