Bryony Leeke
@bryonyleeke.bsky.social
120 followers 540 following 3 posts
Postdoc in the Percharde lab at the MRC LMS studying epigenetics and development. Kiwi in London. Gardener, swimmer, v. amateur birdwatcher.
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Reposted by Bryony Leeke
Reposted by Bryony Leeke
Reposted by Bryony Leeke
dev-journal.bsky.social
Issue 9 is complete!

Cover: Neuronal connections in control (left) and Klp61F neuronal knockdown (right) Drosophila larval brains, labelled with photoconvertible EOS-tagged tubulin. Spectrum color-coded hyperstacks of z-stack images show relative spatial positions of neurons doi.org/10.1242/dev....
Cover of issue 9: Neuronal connections in control (left) and Klp61F (kinesin-5) neuronal knockdown (right) Drosophila larval brains, labelled with photoconvertible EOS-tagged tubulin. Spectrum color-coded hyperstacks of z-stack images were used to show the relative spatial positions of neurons within the brain sample. See Research Article by Lu et al.
Reposted by Bryony Leeke
dev-journal.bsky.social
In this Review, @bryonyleeke.bsky.social, Imke Staffhorst and @mpercharde.bsky.social @mrc-lms.bsky.social explore roles of the nucleolus in mammalian development, focusing on genome organisation and chromatin regulation:
doi.org/10.1242/dev....
Figure 1 Nucleolar structure and rRNA gene organisation.
bryonyleeke.bsky.social
😂 what are the chances! Thank you for your kind words Joaquina.
Reposted by Bryony Leeke
mpercharde.bsky.social
The nucleolus....large, rather boring organelle in the nucleus? No! Our review led by @bryonyleeke.bsky.social just out @dev-journal.bsky.social, highlighting new findings on nucleoli dynamics in development, intriguing roles in chromatin organisation & more.

journals.biologists.com/dev/article/...
nucleoli are dynamically reprogrammed in early mammalian development
bryonyleeke.bsky.social
Happy to say the work from my time in the Turner lab is now published! Check out this thread from the lab account to learn about DNA methylation in marsupial embryos. Massive thanks to all the co-authors!
Reposted by Bryony Leeke
Reposted by Bryony Leeke
lab-turner.bsky.social
We thrilled to see our latest study led by @jeremie-subrini.bsky.social now out in @science.org 🔬

What are the specific functions of each Y-chromosome gene in fertility ? We generated and studied 13 Y-gene KO mouse models to find out! 🧬

www.science.org/doi/full/10....
www.science.org
Reposted by Bryony Leeke
yen-network.bsky.social
❗ANNOUNCEMENT❗
YEN 2025 Conference will be held at @crick.ac.uk on the 19th May 2025.

We are looking forward to another exciting line-up with Nicolas Rivron, Maud Borensztein and Peter Rugg-Gunn.

This year will see a return of the YEN Image Competition so follow for updates.

Share for #YEN2025!