Lightnews — Scholar-powered news

Reposted by Lucas Dent

Joachim Goedhart @joachimgoedhart.bsky.social · 9d

Identification of optimal fluorophores for use in the Drosophila embryo by Timothy E Saunders and team: www.biorxiv.org/content/10.1...

Figure 1: Fluorophore intensity in the Drosophila blastoderm (n.c. 14). Comparison of (A) green and (B) red fluorescence intensity using the same intensity scaling in n.c. 14. The fluorescence signal did
not saturate. Shown are single imaging planes. Normalised histograms of fluorescence intensity for green (C) and red (D) fluorophores averaged across at least n=3 embryos per line. Scale bars = 20 μm

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Reposted by Lucas Dent

Florian Schur @schurlab.bsky.social · 14d

Huntingtin binds and bundles F-actin!
Thrilled to team up with the Humbert (Sorbonne Université) and Song (KAIST) labs on this discovery.
We had a blast doing cryo-ET on this unexpected complex — and now so many new questions lie ahead!
#TeamTomo #CryoET #HTT #actin

doi.org/10.1126/scia...

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Lucas Dent @cellsandculture.bsky.social · Sep 1

Please vote for Frankie’s image 👇 (if you like it!). Frankie is screening compounds to regenerate heart muscle. Your vote will help raise funds for this remarkable work.

Frankie Butera @frankiebutera.bsky.social · Sep 1

Please vote for my #ARTxSCIENCE2025 submission! Voting takes 10 secs

renew.science/artxscience/...

My image shows stem-cell derived heart cells treated with a drug that makes cardiomyocytes (pink) proliferate—without activating fibroblasts #HeartRegeneration #Microscopy #StemCells

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Reposted by Lucas Dent

Giulia Paci @giuliapaci.bsky.social · Aug 11

Thrilled to share the first story from my postdoc! 🎉 A wonderful experiment + simulations collaboration. In the Drosophila wing, we find that 3D cell shapes affect signalling range and fine-tune developmental patterning www.biorxiv.org/content/10.1... Thread below ⬇️

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Lucas Dent @cellsandculture.bsky.social · Jun 13

That is the one!

Lucas Dent @cellsandculture.bsky.social · Jun 13

This! :)

Reposted by Lucas Dent

Lucas Waltzer @lucaswaltzer.bsky.social · Jun 3

#drosophila @flybase.bsky.social request emergency funding:
"As it stands, by the end of July, 2025, there will be no future updates to FlyBase, and in the worst case scenario access to the website will also be lost" => please donate!

www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

www.philanthropy.cam.ac.uk

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Julia Eckert @juliaeckert.bsky.social · May 1

Started my first day as a Walter Benjamin Fellow! 🥳

Looking forward to study symmetry-breaking in morphogenesis using and connecting concepts from soft matter physics & cell/molecular biology @yap-lab.bsky.social. 👉 physics meets biology!

Big thanks to the @dfg.de for funding my research.

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Julia Eckert @juliaeckert.bsky.social · May 25

Our new review paper from @yap-lab.bsky.social is online - together with Virgile Viasnoff!

👉 'New directions in epithelial mechanoadaptation'

www.sciencedirect.com/science/arti...

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Reposted by Lucas Dent

Frank Schnorrer @frankschnorrer.bsky.social · May 10

Titin evolution, titin force and muscle contraction instruct sarcomere dimensions in insect muscles to allow high frequency flight, larval crawling and max force to cut leafs. @ibdm.bsky.social @mpi-nat.bsky.social @jfrupprecht.bsky.social @vincent-loreau.bsky.social
www.science.org/doi/epdf/10....

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Reposted by Lucas Dent

UCL IPLS @ucl-ipls.bsky.social · Apr 8

📢Registration is open for our IPLS Annual Symposium, 11th June 2025!
We will showcase exciting #interdisciplinary #research performed by IPLS researchers and collaborators.
Limited spaces, register early to avoid disappointment 👇
ucl.ac.uk/physics-livi...

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Reposted by Lucas Dent

Andreas Prokop @poppi62.bsky.social · May 2

Has been added to our history collection on droso4public: droso4public.wordpress.com/history/

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Benoit Ladoux @bladoux.bsky.social · Apr 19

Flocking and active solid behavior of epithelial cells in our new study in @pnas.org
Great work of Y. Shen, J. O'Byrne and
@andreasschoenit.bsky.social and collaboration with A. Maitra and R. Voituriez!
| PNAS www.pnas.org/doi/10.1073/...

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Lucas Dent @cellsandculture.bsky.social · Apr 15

We’ve had an incredible experience being hosted at the AIC at Janelia for iPALM imaging. Tremendous support and expertise.
If your project could benefit from advanced imaging, check out their instruments (FIB-SEM, iPALM, LLSM and others) and get in touch.👇

AIC at Janelia @aicjanelia.bsky.social · Apr 15

The latest AIC Call for Proposals is now open! Deadline is June 16, 2025. Come use @hhmijanelia.bsky.social imaging technology and expertise for FREE. Visit www.aicjanelia.org/apply for details. Before applying, contact us to schedule a technical consultation!

Apply | aicjanelia

Apply to use the advanced microscopes housed at the AIC.

www.aicjanelia.org

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Reposted by Lucas Dent

Beth Cimini 🔬💻📊 @bethcimini.bsky.social · Apr 8

If you train people in ImageJ, Fiji, whatever, even if it isn't your day job, please let us know, and please share this post! Thanks a ton, we really appreciate it. (2/2) forms.gle/C8dUpg8qZkbD... #bioimaging #microscopy #bioimageanalysis

Open Source Bioimage Analysis Training Survey

We are attempting for a publication to estimate the number of biologists who have attended a tutorial or training course in open source bioimage analysis (especially user friendly tools, but anything ...

forms.gle

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Reposted by Lucas Dent

Guillaume Jacquemet @guijacquemet.bsky.social · Apr 7

Here we share our opinions on "Practical considerations for data exploration in quantitative cell biology"
journals.biologists.com/jcs/article/...

Joanna, Hanna and I worked quite a bit on this piece and I hope you find it useful
Many thanks to @jcellsci.bsky.social for publishing it

Practical considerations for data exploration in quantitative cell biology

Summary: We present practical guidelines for data exploration in quantitative cell biology that are designed to help yield reliable conclusions and promote a collaborative, transparent approach to dat...

journals.biologists.com

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Reposted by Lucas Dent

Andrew Goryachev @andrewgoryachev.bsky.social · Apr 4

For all you interested in small GTPase biology and membrane pattern formation - this is an essential read from the labs of Peter Bieling and Bill Bement
www.embopress.org/doi/full/10....

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Reposted by Lucas Dent

Erwin Frey @physicsoflifelmu.bsky.social · Mar 31

We may not have really squared the circle — but we came close! 😉 In our @NaturePhysics paper w/ @fakhrilab.bsky.social, light-triggered membrane excitability enables programmable shapes — a step toward engineering living matter.
🔗 www.nature.com/articles/s41...
#biophysics #syntheticcell #softmatter

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Australian BioImage Analysts' Society @ausbias.org · Mar 24

AusBIAS is now on bluesky! We have a website, a logo, and a dream to connect all the bioimage analysts in Australia.

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Ardem Patapoutian @ardemp.bskyverified.social · Mar 21

"How are memories formed and stored in the brain?...Long-term memory acquisition was found to be associated with a selective increase in multisynaptic boutons..". Groundbreaking new study from my friend and colleague Anton Maximov's lab: www.science.org/doi/10.1126/...
Bonus: My son Luca's first pub

Synaptic architecture of a memory engram in the mouse hippocampus

Memory engrams are formed through experience-dependent plasticity of neural circuits, but their detailed architectures remain unresolved. Using three-dimensional electron microscopy, we performed nano...

www.science.org

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Lucien Hinderling @lhinderling.bsky.social · Feb 23

PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓
www.biorxiv.org/content/10.1...

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Tianyang Liu @tianyang22.bsky.social · Jan 31

Working on actin cytoskeleton and Arp2/3 complex? Check out our latest work～https://www.biorxiv.org/content/10.1101/2025.01.31.635869v1
In this work, we found SPIN90 forms a dimer, facilitating bidirectional actin filament nucleation by activating two Arp2/3 complex #Cryo-EM #Actin #Arp2/3

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Harmit Singh Malik @harmitmalik.bsky.social · Jan 28

If you have been affected by the fires in LA, or are concerned about your ability to keep precious Drosophila strains going during the latest funding crisis, we will host your strains as a backup. Please email me.

Please amplify. If you are also able to host fly strains, add your name as well.

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Jérôme Gros @jeromegros.bsky.social · Jan 28

Announcing this upcoming conference:

GASTRULATION RELOADED:
Developing, engineering, and evolving the body plan

Join us as we explore the latest research on gastrulation and axis formation/elongation, featuring common, exotic, and synthetic embryos!

📅 14–17 October 2025
📍 Paris, France

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Eurico Morais-de-Sá @polarityi3s.bsky.social · Nov 15

First official post! A new paper out about #cytokinesis in #epithelia

www.embopress.org/doi/full/10....

Explore our journey as we uncover how regulators of cell-cell and cell-matrix interactions modulate cytokinesis efficiency, while revealing new roles for the Dystrophin-Dystroglycan complex.

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