Claire Wyart
@clairewyart.bsky.social
1.7K followers 300 following 13 posts
Team Leader @Paris Brain Institute & Inserm Director. Fascinated by navigation, movement and brain body interactions. Passion for interdisciplinary training. Knows biodiversity and climate demand changing my game... more on wyartlab.org
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clairewyart.bsky.social
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
clairewyart.bsky.social
Motor Folks: a nice opportunity to present your work & get feedback! BTW registration to the Conference "Searching Principles in Motor Control" on Sept 23-24, 25 is free but mandatory, please sign up and present your work to the French community ! motorconference.sciencesconf.org?lang=en
clairewyart.bsky.social
Hey #motorcontrol researchers! @jul-bouvier.bsky.social, LeMouel & I organize *Searching for principles in Motor Control* Paris Sept 23-24, 25 @sorbonne-universite.fr @institutducerveau.bsky.social @neuropsi.bsky.social: Submit Abstract for Posters by Aug 31! motorconference.sciencesconf.org?lang=en
clairewyart.bsky.social
We work on humans with @antoniocbscosta.bsky.social @marcoromanato.bsky.social @wyartlab.bsky.social predicting effects of #DBS in Parkinson's Disease patients. Yet, understanding cellular & circuit mechanisms underlying behaviour require model organisms 🎏🐭🪱🪰 & cannot be done in humans nor organoids
labonnelab.bsky.social
Dear all, PLEASE add comments on the importance of model organism research at this link:
Reposted by Claire Wyart
izfs.bsky.social
Congratulations to the 2025 George Streisinger Award Winners! And, thank you, to your contributions to the #zebrafish field! #IZFC2025
Reposted by Claire Wyart
graycamplab.bsky.social
Neuron programming! Pro-neural TFs + 480 morphogen conditions + scRNA-seq --> Diverse iN subtypes of forebrain, midbrain, hindbrain, spinal cord, and PNS. @hsiuchuanlin.bsky.social@jasperjanssens.bsky.social‬ and Treutlein Lab! @science.org www.science.org/doi/10.1126/... #NGN2 #ASCL1
Reposted by Claire Wyart
elife.bsky.social
Chronic back pain affects most of us eventually, and ageing discs are often to blame. But cellular senescence may not be irreversible.

This Insight Article explores how platelet-derived growth factors could help revive ageing disc cells.
buff.ly/VjINkon
Senescence: Returning aging cells to productivity
Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
buff.ly
Reposted by Claire Wyart
ferencmueller.bsky.social
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
Reposted by Claire Wyart
burgesslab.bsky.social
Ferenc is great, super opportunity!
ferencmueller.bsky.social
Dear #izfc2025 participants, if anyone of you are interested in how transcription control defines mRNA fate and translation in zebrafish development, there are/will be several PhD and postdoctoral positions (funded by the Wellcome Trust) for this research. Please find me if interested.
Reposted by Claire Wyart
blockintheback.bsky.social
The winners of the 2025 George Streisinger Award are the Course Directors of the Zebrafish Development and Genetics course at MBL, for their tremendous contributions to our amazing community for >25 years! #izfc2025
Reposted by Claire Wyart
labonnelab.bsky.social
Dear all, PLEASE add comments on the importance of model organism research at this link:
Reposted by Claire Wyart
animal-prattle.bsky.social
V cool work from @ebriefer.bsky.social et al on how selection for sociability alters vocal signals (in sheep!) bit.ly/40AHKTd

1. Isolation but not feeding calls distinguish 🐑 selected for high vs low sociability

2. More selection for sociability ➡️ Less vocal individuality

#prattle 💬 #bioacoustics
Figure 1: Acoustic differences in isolation bleats (left side of panel) and in pre-feeding bleats (right side of panel) according to the ‘line’ (S+, S- and intermediate not selected when considering the isolation calls). A: Spectrogram of calls of one representative S+ female and one representative S- female according to the context of recording (FFT wl = 2048 pts, ov=90%, frequency sampling=44.1 kHz, amplitude range from blue to red color scale: -70 to 0dB). B: Averaged mean-spectrum (and standard deviation in shade) over the total amount of calls analyzed per line and contexts (Number of isolation calls: N=322 from S+, N=67 from S-, N=899 from not selected females; Number of pre-feeding calls: N=262 from S+, N=257 from S- females). C: Acoustic parameters explaining the Acoustic Score computed using a LDA on ‘line’ within
each context of recording (isoLD for isolation and pre-feedLD for pre-feeding). For isolation calls, the predictions of isoLD for calls recorded in non-selected females and comparisons (groups with different letters illustrate statistical differences, see supplementary statistical tables S3 for model estimates and pairwise comparisons).
Reposted by Claire Wyart
benjulab.bsky.social
Introducing warpfield, an open source Python library for GPU-accelerated non-rigid 3D registration. Warps and aligns gigavoxel volumes within seconds (not hours). For 3D microscopy, region-to-region and cell-to-cell matching.
A collaboration with @mh123.bsky.social 🚀
github.com/danionella/w...
Reposted by Claire Wyart
polavieja.bsky.social
It took us many years to improve idtracker.ai in both accuracy and tracking time. Here it is.
Reposted by Claire Wyart
wyartlab.bsky.social
Downstream @etlunsford.bsky.social mapped how the corresponding interneurons in the brainstem project onto reticulospinal neurons to select the steering command eliciting either forward or turns ... recalling the pioneering work of @daniobrain.bsky.social on optical motor response to flow! (5)
Reposted by Claire Wyart
wyartlab.bsky.social
The tackle this question, @etlunsford.bsky.social 🌬️ stimulated each & all neuromasts along the body & discovered a simple principle within the brainstem !! Namely, information on location & direction is encoded in an egocentric referential around the center of mass! www.biorxiv.org/content/10.1...
Reposted by Claire Wyart
wyartlab.bsky.social
Fish display mechanosensors called neuromasts covering their body from head to tail. In each neuromast, hair cells can sense changes in water flow along different directions in the anteroposterior axis, either tailward or headward. How does the brain compute the flow information across the body? (2)
Reposted by Claire Wyart
wyartlab.bsky.social
By combining controlled mechanical stimulation & whole brain #imaging, @etlunsford.bsky.social revealed an essential principle 💡... Mechanosensory inputs from any directions along the body are encoded relative to the center of mass (COM)! Recalling #olfaction with odors encoded by pleasantness (4)
Reposted by Claire Wyart
wyartlab.bsky.social
Let's share @etlunsford.bsky.social's work : to survive, animals avoid drifting involuntarily in their environment. While humans rely on visual & vestibular cues, birds & fish need to sense complex flow changes of the external fluid (air/water) around them to select motor actions. How do they do?(1)
clairewyart.bsky.social
hi BlueSky, introducing @wyartlab.bsky.social @zebrafishrock.bsky.social "cuvée" 🍷 biodynamic organic & bubbly 2025!! Located in @institutducerveau.bsky.social 🎏 migrating in summer @sorbonne-universite.fr to observatory or in @standrewspsyneuro.bsky.social to learn #MotorControl, #morphogenesis!
clairewyart.bsky.social
⚡Awesome days of scientific discussions around the topic of resilient motor circuits in Parkinson's disease & underlying genetic conditions featuring Prof. Alexis Brice, Leonard Constien, Ananelle Redon, Ninon Peysson @kevinfidelin.bsky.social among others⚡
Reposted by Claire Wyart
kevinfidelin.bsky.social
🚨Job opportunity 🚨

The @clairewyart.bsky.social 's lab, at the @institutducerveau.bsky.social is looking for a lab manager to help us cracking the molecular underpinnings of motor circuits in vivo and across species !
clairewyart.bsky.social
🧿 Excited about molecular biology & genetics 🧬🧬🧬? Wanna live in Paris? Join our team as a lab manager under the supervision of @kevinfidelin.bsky.social & myself! Personal development in professional environment is our mission. Inclusive space where proactive and playing collective people flourish 🧿
clairewyart.bsky.social
Great seminar this morning scheduled this morning from Andre Brown @imperialcollegeldn.bsky.social @institutducerveau.bsky.social dont miss it !
drosostalis.bsky.social
📣SEMINAR📣 Come along @institutducerveau.bsky.social to hear Andre Brown from @imperialcollegeldn.bsky.social speak about his work on computational ethology for disease modelling and drug screening! 🪱
clairewyart.bsky.social
Congrats Laura, your science (and neuronal morphologies) is (are) beautiful ✨🌳
landreae.bsky.social
Very grateful to @leverhulmetrust.bsky.social for funding this project @devneuro.bsky.social in collaboration with mathematician Karen Page @uclofficial.bsky.social on how neurons get their amazing shapes!
kingsioppn.bsky.social
Prof @landreae.bsky.social has been awarded a @leverhulme.bsky.social project grant to uncover the rules behind neuronal development #neuroskyence

www.kcl.ac.uk/news/laura-a...