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Reposted by Carine Meignin 🪰🦠🧬🌈

EDRC2025 @edrc2025.bsky.social · 15d

Three fantastic keynote lectures to kick off #EDRC2025 Lucia Prieto-Godiño @crick.ac.uk the @embo.org sponsored lecture, Romain Levayer @pasteur.fr and Marta Llimargas @ibmb-csic.bsky.social

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · Jun 7

Contrats to Dominique Ferrandon’s team @adrienfranchet.bsky.social

eLife @elife.bsky.social · Jun 7

Hidden virus harboured by fruit flies may influence experimental accuracy.
buff.ly/TtHCYLQ

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Reposted by Carine Meignin 🪰🦠🧬🌈

The EMBO Journal @embojournal.org · Jun 6

REFEREE 1: “I conclude with a simple, direct statement - this is the best paper I have read all year!”
#TransparentPeerReview

Co-evolving infectivity and expression patterns drive the diversification of endogenous retroviruses
@juliusbrennecke.bsky.social et al

www.embopress.org/doi/full/10....

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · Jun 3

The world has gone mad. Thinking of Michael Ashburner today - his vision and dedication to the scientific community remain an inspiration, reminding us of how science should be: open, collaborative, and driven by curiosity.

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Mark A. Hanson @hansonmark.bsky.social · Jun 3

URGENT: FlyBase has lost practically all its funding overnight; even user fees are tied up in denied grant funding. 🤬🤯

Any lab using @flybase.bsky.social please donate using the link in post below.

This incredible community, on whose backs our #Drosophila labs depend, can't be left out to dry.

Marc Dionne @marcsdionne.bsky.social · Jun 3

My lab studies bacterial infections. We spend a lot of time looking at (or for) species-specific genetic and genomic databases for hosts and microbes. FlyBase is the best of all—there is literally no comparison. Its existence is under threat. Please donate.
www.philanthropy.cam.ac.uk/give-to-camb...

Drosophila Genetic Database

The Drosophila Genetic Database, FlyBase, is on the brink of collapse due to the sudden termination of the FlyBase NIH grant, which includes salaries for 5 literature curators based at the University ...

www.philanthropy.cam.ac.uk

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Reposted by Carine Meignin 🪰🦠🧬🌈

Fillip Port @crisprflydesign.bsky.social · May 26

Why use #CRISPR in #Drosophila when RNAi works so well? Because for some genes well is not good enough.

Check out new preprint from the lab demonstrating a role for Vps15 in Wingless trafficking. Something that was missed in several RNAi screens.

www.biorxiv.org/content/10.1...

Images from the linked preprint showing Wingless stainings in the Drosophila wing imaginal disc. Targeting vps15 with two indepependent RNAi lines (paper also shows the same with a third line) does not result in a phenotype. In contrast, targeting vps15 with two independent sgRNA constructs and Cas9 results in strong accumulation of Wingless protein in perturbed cells.

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Reposted by Carine Meignin 🪰🦠🧬🌈

Anne Straube @annestraube.bsky.social · May 17

Looking forward to the Physics within the Cell workshop on 16th June. Join if you want to discuss molecular motors and intracellular transport with me. More info here: iop.eventsair.com/pwtc2025/

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Reposted by Carine Meignin 🪰🦠🧬🌈

Sternberg Lab @sternberglab.bsky.social · May 15

1/10 Today in @science.org in collaboration with
the Liu group we report the development of a laboratory-evolved CRISPR-associated transposase (evoCAST) that supports therapeutically relevant levels of RNA-programmable gene insertion in human cells. drive.google.com/file/d/1I-Ub...

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Reposted by Carine Meignin 🪰🦠🧬🌈

Mark A. Hanson @hansonmark.bsky.social · May 16

📣 #Drosophila news! 🪰

The AMP mutant lines from Hanson et al. (bit.ly/eLifeHanson) & the many isogenic immunity strains generated by @lmvteixeira.bsky.social & @brunolemaitre.bsky.social groups are now in @vdrc-flies.bsky.social!

Find the 40 DrosDel Immunity Panel strains in VDRC library DD-Im ⬇️

Search results for: 'DrosDel Immunity panel'

shop.vbc.ac.at

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · May 15

📣 Junior PI Opportunity
Join CNRS Strasbourg to lead cutting-edge research on host-pathogen interactions in insects 🪰
450k€ package | Drosophila, RNA, immunity
IBMC + Labex NetRNA network
📅 Apply by June 30, 2025
🔗 ibmc.cnrs.fr/en/laboratoi...
#RNA #Insects #Drosophila #NetRNA #Immunity #JobAlert

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · May 8

Checkout our last paper about Dicer-2 interactome in vivo dx.plos.org/10.1371/jour... #RNAi #Dicer #Drosophila

In vivo Dicer-2 interactome during viral infection reveals novel pro and antiviral factors in Drosophila melanogaster

Invertebrates rely mainly on RNA interference (RNAi) as a key defense mechanism against viral infections. The central protein of this process is an enzyme called Dicer-2, which senses and processes vi...

dx.plos.org

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bioRxiv Developmental Biology @biorxiv-devbio.bsky.social · Apr 3

An intercellular metabolic relay for brain sparingin Drosophila https://www.biorxiv.org/content/10.1101/2025.04.02.645514v1

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Daryl Gohl @darylgohl.bsky.social · Mar 22

Hey fellow Drosophila researchers - if you haven't heard, the UMGC is offering ultra low-cost genome sequencing! See here to learn more: z.umn.edu/UMGC-MOSS #Dros25

University of Minnesota Genomics Center Model Organism Sequencing Service Flyer. $25 for a 30x Drosophila genome.

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · Mar 3

Application for Master in Integrative Biological Sciences (iBioS) - Apply on MonMaster before March 24th. Details on the flyer. imcbio.unistra.fr/imcbio-train...

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Reposted by Carine Meignin 🪰🦠🧬🌈

Lucie Etienne @lucievirevolte.bsky.social · Feb 7

We are looking for a #postdoc to discover cell-autonomous innate immune antiviral factors in mammals, based on newly-identified defense of prokaryotes!
#EvoCure #comparativeImmunology #virology
Please share
@inserm.fr @ciri-lyon.bsky.social @cnrsbiologie.bsky.social
ciri.ens-lyon.fr/teams/lp2l/j...

Postdoc position in comparative immunology and virology — Centre International de Recherche en Infectiologie

A 1-year renewable postdoctoral researcher position is available in our lab (PI: Lucie ETIENNE, CIRI, ENS-Lyon) to discover new antiviral cell-autonomous innate immune factors in mammals, based on new...

ciri.ens-lyon.fr

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Reposted by Carine Meignin 🪰🦠🧬🌈

RNA Society @rnasociety.bsky.social · Feb 4

We are pleased to announce registration for RNA 2025 - the 30th Annual Meeting of the RNA Society - is now open!
www2.rnasociety.org

This year’s meeting will be held at the beautiful Town and Country Resort & Convention Center in sunny San Diego, California, USA from May 27th - June 1st, 2025.

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Reposted by Carine Meignin 🪰🦠🧬🌈

Kurianlab @kurianlab.bsky.social · Feb 5

www.cell.com/cell/fulltex...

@marvintanenbaum.bsky.social

Fantastic study by the Tanenbaum lab

Long-term imaging of individual ribosomes reveals ribosome cooperativity in mRNA translation

Ribosomes cooperate through transient collisions to ensure efficient translation.

www.cell.com

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Reposted by Carine Meignin 🪰🦠🧬🌈

Mark A. Hanson @hansonmark.bsky.social · Jan 30

ECR fellowship for 2 years abroad. Excellent funding & offers the chance to build your own research direction.

📣 I have a non-model #Drosophila system ripe for collaboration - it's got a balancer chromosome, so GAL4/UAS becomes feasible. #EvolBio questions with functional genetics! Happy to chat.

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Reposted by Carine Meignin 🪰🦠🧬🌈

Sorek Lab @soreklab.bsky.social · Jan 23

Our paper out @CellCellPress: Structure guided discovery of viral proteins that inhibit host immunity

Congrats Erez Yirmiya, Azita Leavitt, Gil Amitai, our collaborators at the Kranzusch lab, and coauthors

A 🧵 1/10

www.cell.com/cell/abstrac...

Structure-guided discovery of viral proteins that inhibit host immunity

Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify those that bind and antagonize host immune proteins. Detected proteins are shown to inhibit no...

www.cell.com

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · Jan 17

📢Job alert

We have two postdoctoral positions available, starting in Spring 2025. These positions are part of research funded by an ERC Advanced Grant, focused on exploring evolutionary immunology (Evo-Immuno). #Postdoc #InnateImmunity

Do not hesitate to contact us. ibmc.cnrs.fr/en/laboratoi...

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Reposted by Carine Meignin 🪰🦠🧬🌈

Marco Hein @marco.heinlab.org · Jan 14

Time to share our organelle proteome paper
out in @cellcellpress.bsky.social: doi.org/nzwz
We created a spatial map of human cells using organelle immunoprecipitation at scale.
Locate your fav protein among the 7,600 we mapped across 19 subcellular compartments: organelles.sf.czbiohub.org/

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Graphical abstract of the Organelle Profiling paper, showing the workflow:
Endogenously tagged organelle library;
Native IP proteomics;
Data-driven graph clustering;
resulting in a subcellular proteome map with
more than 7,600 proteins localized across 19 subcellular compartments.

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Carine Meignin 🪰🦠🧬🌈 @cmeignin.bsky.social · Jan 13

📢Job alert

Are you interested in Drosophila genetics, insects, innate immunity, evolution? We are offering an exciting Group Leader position within the NetRNA consortium (labex-netrna.cnrs.fr/presentation...)

See below for more information and do not hesitate to contact us.

Junior group leader position | European Drosophila SocietyHome

europeandrosophilasociety.org

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Kasia Siudeja @ksiudeja.bsky.social · Jan 13

Calling all Junior(-ish) Drosophila Investigators 📣📣📣

Join us in June for the JEDIs Resurection :
flies-jedi.github.io/projects/202...

✅presentations from participants,
✅panel on publishing (with fantastic guests)
✅plenty of time for socializing

Register asap to help us with the first headcount

Junior European Drosophila Investigators | JEDI meeting 2025

first post COVID19 meeting --REGISTER before Feb.28

flies-jedi.github.io

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Reposted by Carine Meignin 🪰🦠🧬🌈

François Leulier @francoisleulier.bsky.social · Dec 6

Drosophila and Lactiplantibacillus plantarum in the spotlight (again), what a wonderful model (disclaimer I am biased ;-) ).

Congrats Will and team!

www.science.org/doi/10.1126/...

A conserved bacterial genetic basis for commensal-host specificity

Animals selectively acquire specific symbiotic gut bacteria from their environments that aid host fitness. To colonize, a symbiont must locate its niche and sustain growth within the gut. Adhesins are...

www.science.org

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Reposted by Carine Meignin 🪰🦠🧬🌈

Mark A. Hanson @hansonmark.bsky.social · Nov 8

ICYMI: we wrote a book. It's a free PDF, but you can also get a physical copy just in time for the holidays. Probably. I dunno. We don't actually get money from it.

This was a labour of love by Hannah & Bruno. Also I helped. Stocking stuffer idea: USB loaded with The #Drosophila Immunity Handbook 🪰

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