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Coraline Mlynarczyk @coraline-mly.bsky.social · Sep 6

very inspiring ride! next year: 65 mi 💪

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Coraline Mlynarczyk @coraline-mly.bsky.social · Sep 4

brought back great memories of my own first submissions with Ari Melnick ☺️

Coraline Mlynarczyk @coraline-mly.bsky.social · Sep 4

first postdoctoral fellowship application of the lab is in! Congrats @yulaizhou.bsky.social 🎉 excited about the proposal you put together!!!

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Coraline Mlynarczyk @coraline-mly.bsky.social · Sep 3

congrats Sarah! challenge of moving lab abroad passed with flying colors, can’t wait to see what you do in the coming year 😁

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Coraline Mlynarczyk @coraline-mly.bsky.social · Aug 16

Please consider supporting cancer research and cancer patient care. We are riding our bikes on Sep 6. Even a few $$ can go a long way. Let’s end cancer!!

www.rideclosertofree.org/participants...

A fundraising page for Coraline Mlynarczyk

Join the Closer to Free Ride on Saturday, September 6th. Register or donate at RideCloserToFree.org.

www.rideclosertofree.org

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Reposted by Coraline Mlynarczyk

Immunology & Microbial Pathogenesis (IMP) Program @wcm-imp.bsky.social · Aug 10

Fantastic to see two former IMP postdocs @thepenkpanther.bsky.social and @coraline-mly.bsky.social highlighted by JEM in this Viewpoint! #WomeninSTEM

Journal of Experimental Medicine @jem.org · Aug 8

In this Viewpoint, we asked women researchers across multiple research fields about their story of becoming an independent researcher and unique challenges they face as #WomenInSTEM in their respective scientific environments: rupress.org/jem/article/...

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Reposted by Coraline Mlynarczyk

Journal of Experimental Medicine @jem.org · Jul 29

📢 We're now accepting applications for the JEM Early Career Travel Award, for grad students & early-career postdocs to participate in a scientific conference! This year, the award will support the attendance of #Cytokines2025 @cytokinesociety.bsky.social! Apply here 👉 rupress.org/jem/pages/ea...

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Reposted by Coraline Mlynarczyk

Eric Wang @wanglab.bsky.social · Jul 10

Thrilled to share our lab’s first paper, just out in Blood Cancer Discovery @theaacr.bsky.social!
We uncovered an isoform-specific RUNX1C–BTG2 axis that drives chemoresistance in AML.
aacrjournals.org/bloodcancerd...

An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.

Abstract. Aberrant levels or structures of RNA isoforms are a hallmark of many cancers, including acute myeloid leukemia (AML), yet its role in AML chemoresistance remains unclear. We conducted a pair...

aacrjournals.org

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Coraline Mlynarczyk @coraline-mly.bsky.social · Jul 3

Lunch outing with the lab*
to welcome Nina for the summer and celebrate the 1 year 🎂 of the lab - could not be more happy and proud of everything accomplished by the team already! And special thanks @s-j-aitken.bsky.social for the incredibly kind note ☺️
(*no research $$ were used)

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Coraline Mlynarczyk @coraline-mly.bsky.social · Jul 2

congrats David on the amazing news!!!

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Reposted by Coraline Mlynarczyk

immunoboys @immunoboys.bsky.social · Jul 1

S1P is produced in the outer lymph follicle area and degraded by B cells resulting in a negative gradient towards to follicle center. S1PR2 signalling on GC B cells leads to migration arrest, keeping B cells within the follicle. (🐭 data)

Green et al 2011 🧪⑂
www.nature.com/articles/ni....

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Coraline Mlynarczyk @coraline-mly.bsky.social · Jun 29

On Sep 6 we are riding to raise funds for cancer research and patient care.
Join the #Cyclopaths team to ride with us! Can chose 10/25/40/65/100 miles 🚴

or support the effort with a donation :)

www.rideclosertofree.org/index.cfm?fu...

www.rideclosertofree.org/index.cfm?fu...

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Coraline Mlynarczyk @coraline-mly.bsky.social · Jun 7

and also, does it link to development of cancer from the immune system? B cell lymphoma incidence +++ with aging

Michelle Linterman @linterman.bsky.social · Jun 6

Great to have the @jimmunol.bsky.social special collection, “Aging's impact on the immune system” out. academic.oup.com/jimmunol/pag...

Aging's impact on the immune system

Description This 2025 collection of The Journal of Immunology features a special collection of articles curated by guest editor Patricia Gearhart. The collecti

academic.oup.com

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Coraline Mlynarczyk @coraline-mly.bsky.social · Jun 2

very cool findings from Andrew Wang, David Hafler and Noah Palm teams @yaleschoolofmed.bsky.social

www.nature.com/articles/s41...

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Reposted by Coraline Mlynarczyk

Yale Cancer Center @yalecancer.bsky.social · May 31

"I research #cancer because… any cell in our body can become cancerous through a multitude of trajectories."
@coraline-mly.bsky.social
➡️https://yalecancercenter.org/news-article/national-cancer-research-month-with-dr-coraline-mlynarczyk/
@yale-hematology.bsky.social @theaacr.bsky.social
#NCRM25

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Coraline Mlynarczyk @coraline-mly.bsky.social · Apr 26

The MSK lymphoma symposium was a great opportunity to learn, discuss the future of lymphoma research and connect with a great group of people, looking forward to attending again! #MSKlymphomaCME

Memorial Sloan Kettering Continuing Medical Education @mskcme.bsky.social · Apr 24

Excited to kick off the 9th MSK Symposium on #Lymphoma tomorrow with a plenary lecture from Dr. Christopher Flowers. Honored to welcome a distinguished faculty and look forward to a compelling program. Details: bit.ly/Lymphoma2025 #MSKlymphomaCME @mskcancercenter.bsky.social @gillessa.bsky.social

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Reposted by Coraline Mlynarczyk

immunoboys @immunoboys.bsky.social · Apr 24

Tissue-resident memory T cells have high levels of mRNA of proinflammatory cytokines but produce the proteins only upon stimulation. 🧪⑂
The integrated stress response inhibits mRNA translation in these cells, having these cells poised for rapid responses in 🐭 and 🧓. 1/2

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Reposted by Coraline Mlynarczyk

The Rockefeller University @rockefeller.edu · Mar 19

New imaging from @victora.bsky.social's lab reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. #RockefellerScience

New mechanism behind adaptive immunity revealed. It could impact how we design vaccines. - News

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted...

www.rockefeller.edu

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Coraline Mlynarczyk @coraline-mly.bsky.social · Apr 23

Sad to see you leave the US Ari but great new start!!! The @carrerasijc.bsky.social institute is lucky to have you join their mission!

Josep Carreras Leukaemia Research Institute @carrerasijc.bsky.social · Apr 22

We're pleased to announce that Dr Ari Melnick has been appointed new Director of the Josep Carreras Institute.

Dr Melnick will lead IJC in our mission to advance #research in #leukaemia and other malignant blood diseases.

Read the full release here: www.carrerasresearch.org/en/news/dr-a...

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Coraline Mlynarczyk @coraline-mly.bsky.social · Apr 12

sharing the joy of this week 😁 with our first lab presentations by Mahid and Divyeksha, at the Yale HTI (human & translational immunology program) retreat. so proud of them, they did wonderful!

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Reposted by Coraline Mlynarczyk

Prof. Shane Crotty @profshanecrotty.bsky.social · Apr 7

One of our obsessions in the Crotty lab is to better understand B-cell immunology in the context of vaccines. Rare B cells can have antibody specificities particularly important for protection against some diseases. In our most recent paper…
@cp-immunity.bsky.social
www.cell.com/immunity/ful...

Diverse priming outcomes under conditions of very rare precursor B cells

B cells that give rise to neutralizing antibody responses can be extremely rare in the naive B cell repertoire. Madden et al. show that delivery strategy and adjuvant selection affect the recruitment ...

www.cell.com

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Coraline Mlynarczyk @coraline-mly.bsky.social · Mar 31

Thank you The Mark Foundation @themarkfdn.bsky.social & The Follicular Lymphoma Foundation for supporting this important research. Honored to work on this project with Rong Fan @rongfan8.bsky.social & Mina Xu

The Mark Foundation for Cancer Research @themarkfdn.bsky.social · Mar 27

Another ASPIRE Award supports Rong Fan, Mina Xu, & Coraline Mlynarczyk at @yaleschoolofmed.bsky.social. Their research will use advanced spatial omics to map genetic changes & the microenvironment of FL tumors, predicting progression & treatment responses.
themarkfoundation.org/portfolio/en...

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Reposted by Coraline Mlynarczyk

The Mark Foundation for Cancer Research @themarkfdn.bsky.social · Mar 27

Announcing two new ASPIRE Awards! The Follicular Lymphoma Foundation & The Mark Foundation are partnering to fund two teams working to identify biomarkers to predict #FollicularLymphoma disease progression & transformation. #CureFL
themarkfoundation.org/2025/03/driv...

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Reposted by Coraline Mlynarczyk

Gabriel Victora @victora.bsky.social · Mar 19

Cool germinal center acrobatics from Juhee Pae et al, check it out!

www.nature.com/articles/s41...

www.nature.com

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Coraline Mlynarczyk @coraline-mly.bsky.social · Mar 10

recommend watching Dark Waters if you haven’t yet

www.theguardian.com/commentisfre...

We’re facing a ‘forever chemicals’ crisis. We must stop Pfas at the source

Pfas are poisoning our soil and polluting our lungs. The EPA is finally sounding the alarm – but that’s not enough

www.theguardian.com

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