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Reposted by David Tovey

Kate Dunn @katemdunn.bsky.social · Dec 18

In J Clin Epi I've published a couple of papers on questionnaire design pubmed.ncbi.nlm.nih.gov/12589865/ & pubmed.ncbi.nlm.nih.gov/18945586/ plus one on clinically important differences pubmed.ncbi.nlm.nih.gov/16360560/

Does questionnaire structure influence response in postal surveys? - PubMed

This study tested the effect of questionnaire structure on response, speed of return, and content of answers in a postal survey. All 259 patients aged 30-59 years who consulted with back pain at four ...

pubmed.ncbi.nlm.nih.gov

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · 10d

Reusing clinical trial data to consolidate and advance medical knowledge - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Reusing clinical trial data to consolidate and advance medical knowledge

While data sharing holds great potential to maximize the value of research and reduce waste, these benefits can only be fully realized if shared data are also effectively reused. Yet data reuse remain...

www.jclinepi.com

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Reposted by David Tovey

Jack Wilkinson @jdwilko.bsky.social · Sep 8

For Monday crowd. INSPECT-SR, a tool to help you identify problematic (inc. fraudulent) RCTs, now available.

Jack Wilkinson @jdwilko.bsky.social · Sep 5

www.medrxiv.org/content/10.1...

INSPECT-SR: A tool for assessing trustworthiness of randomised controlled trials.

INSPECT-SR: a tool for assessing trustworthiness of randomised controlled trials

The integrity of evidence synthesis is threatened by problematic randomised controlled trials (RCTs). These are RCTs where there are serious concerns about the trustworthiness of the data or findings....

www.medrxiv.org

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David Tovey @davidit.bsky.social · May 14

Thanks for such a brilliant commentary. Transparency is necessary but not sufficient in many circumstances

Lex Bouter @lexbouter.bsky.social · May 8

@jclinepi.bsky.social kindly invited me to express my thoughts on handling #ConflictsOfInterest of authors of scholarly publications. bit.ly/431UYIQ
@nrin-integrity.bsky.social @opensciencenl.bsky.social @peerreviewcongress.bsky.social @davidit.bsky.social @lseimpactblog.bsky.social

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 22

Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review

To support systematic reviewers new to network meta-analysis (NMA), we (i) identified and described published methods resources for conducting systematic reviews (SRs) with NMA of randomized controlle...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 22

A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A scoping review identifies comments suggesting modifications to PRISMA-P 2015

To identify, summarise, and analyse published comments relevant to the PRISMA-P (Preferred Items for Reporting Systematic reviews and Meta-Analyses Protocols) 2015 reporting guideline for systematic r...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 22

Priority-setting criteria for clinical practice guideline development on rare genetic neurodevelopmental disorders: a Delphi study within the European Reference Network (ERN) ITHACA - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Priority-setting criteria for clinical practice guideline development on rare genetic neurodevelopmental disorders: a Delphi study within the European Reference Network (ERN) ITHACA

The prioritization of clinical practice guideline (CPG) efforts is particularly challenging for rare genetic neurodevelopmental disorders given the large number of (ultra)rare conditions and limited r...

www.jclinepi.com

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David Tovey @davidit.bsky.social · Mar 24

Disappointing but perhaps not surprising

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 22

Epidemiology and reporting characteristics of systematic reviews of clinical prediction models:a scoping review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Epidemiology and reporting characteristics of systematic reviews of clinical prediction models:a scoping review

This study aimed to explore research trends and areas of interest in systematic reviews (SRs) and meta-analyses of clinical prediction models (CPMs), while summarizing their conduct and reporting char...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 20

Our message is one of hope, and we see this as a time of opportunity for leaders in the field to stand up for sound methods and high-quality science.

Editorial, April 2025
www.jclinepi.com/article/S089...

Editorial, April 2025

Drafting the monthly round-up of noteworthy manuscripts to be published in the corresponding issue of the Journal of Clinical Epidemiology (JCE) is both a privilege and pleasure. The task includes rer...

www.jclinepi.com

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Reposted by David Tovey

Suzie Cro @suziecro.bsky.social · Mar 18

New publication led by @proflouisemarston.bsky.social using multiple imputation to target a hypothetical estimand in a pandemic restriction-free world for a trial in
schizophrenia - demonstrating the potential impact of the pandemic on the trial results

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 13

Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand

Many trials are affected by unforeseen events after recruitment has commenced. The aim of this study is to explore a hypothetical strategy for dealing with an intercurrent event that occurred during t...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 17

#keyconcepts Statistical strategies to analyze local control after radiotherapy - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Statistical strategies to analyze local control after radiotherapy

Historically, local progression, an outcome of effectiveness in curative radiotherapy, has not always been statistically analyzed with the same method. This article aims to elucidate the validity and ...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 17

Calculating Follow-Up Completeness: a comparison of multiple methods under different simulated scenarios and a use-case - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Calculating Follow-Up Completeness: a comparison of multiple methods under different simulated scenarios and a use-case

Completeness of follow-up is a crucial aspect of data quality in cohort studies and clinical trials. This study aims to provide an overview of different methods to calculate follow-up completeness. Ad...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 17

Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Methods resources for authors new to conducting systematic reviews with network meta-analysis: A Scoping Review

To support systematic reviewers new to network meta-analysis (NMA), we (i) identified and described published methods resources for conducting systematic reviews (SRs) with NMA of randomized controlle...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Mar 17

A scoping review identifies comments suggesting modifications to PRISMA-P 2015 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

A scoping review identifies comments suggesting modifications to PRISMA-P 2015

To identify, summarise, and analyse published comments relevant to the PRISMA-P (Preferred Items for Reporting Systematic reviews and Meta-Analyses Protocols) 2015 reporting guideline for systematic r...

www.jclinepi.com

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David Tovey @davidit.bsky.social · Feb 22

Great to see journals based in the US and elsewhere standing up for scientific integrity.

PLOS Biology @plosbiology.org · Feb 21

PLOS has issued a statement on recent US Executive Orders and scientific integrity.

We are determined to stand firmly behind our mission, our values and our principles, and against any attempt at censorship or undermining of the core principles of scientific inquiry.

plos.io/3D4O8cH

PLOS statement on recent US Executive Orders and scientific integrity - The Official PLOS Blog

Since its founding over twenty five years ago PLOS has been dedicated to advancing open science, ensuring that knowledge is accessible to…

plos.io

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 21

Corrigendum to ʻMethodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies’. Journal of Clinical Epidemiology 145 (2022) 55–69 - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Corrigendum to ʻMethodological systematic review recommends improvements to conduct and reporting when meta-analyzing interrupted time series studies’. Journal of Clinical Epidemiology 145 (2022) 55–6...

In the original article, the supplementary file included our revisions as tracked changes arising from the peer-review process. Attached is an updated supplementary file where the tracked-changes have...

www.jclinepi.com

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David Tovey @davidit.bsky.social · Feb 14

So sorry to read this Richard. All best wishes to you and your family

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David Tovey @davidit.bsky.social · Feb 13

Thanks for this notifcation Florian but I feel obliged to point out that @jdwilko.bsky.social was very much the first and lead author!

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David Tovey @davidit.bsky.social · Feb 13

Delighted to see our @jclinepi.bsky.social commentary on redundant publication and potential research waste in the field of reporting guidelines is now fully online and accessible for 50 days via this link: authors.elsevier.com/c/1kbcJ3BcJQ...

authors.elsevier.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 2

You wait ages and then two arrive at once: reporting guidelines shouldn’t be like buses - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

You wait ages and then two arrive at once: reporting guidelines shouldn’t be like buses

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 2

Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Risk of bias assessment tools often addressed items not related to risk of bias and used numerical scores

We aimed to determine whether the existing risk of bias assessment tools addressed constructs other than risk of bias or internal validity, and whether they used numerical scores to express quality, w...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 5

Scoping review of registration of observational studies finds inadequate registration policies, increased registration, and a debate converging towards pro-registration - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Scoping review of registration of observational studies finds inadequate registration policies, increased registration, and a debate converging towards pro-registration

We aimed to examine a) the policies of national and international clinical trial registries regarding observational studies; b) the time-trends of observational study registration; c) the published ar...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 5

Heterogeneity across outcomes in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors in chronic heart failure: cross-sectional study - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Heterogeneity across outcomes in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors in chronic heart failure: cross-sectional study

This study aimed to analyze the outcomes, outcome domains, and prevalence of the use of clinical outcome endpoints (COE) in clinical trials on sodium-glucose cotransporter 2 (SGLT2) inhibitors for chr...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 5

Visualizing the Value of Diagnostic Tests and Prediction Models, Part I. Introduction and Expected Gain in Utility as a Function of Pre-Test Probability - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Visualizing the Value of Diagnostic Tests and Prediction Models, Part I. Introduction and Expected Gain in Utility as a Function of Pre-Test Probability

Expected gain in utility (EGU) and EGU graphs are used to evaluate diagnostic tests and risk prediction models. EGU is the expected gain or loss in utility of treating or testing relative to not treat...

www.jclinepi.com

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Reposted by David Tovey

Journal of Clinical Epidemiology @jclinepi.bsky.social · Feb 5

Visualizing the Value of Diagnostic Tests and Prediction Models, Part II. Net Benefit Graphs: Net Benefit as a Function of the Exchange Rate - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

Visualizing the Value of Diagnostic Tests and Prediction Models, Part II. Net Benefit Graphs: Net Benefit as a Function of the Exchange Rate

Net benefit (NB) calculations and NB graphs are used to evaluate diagnostic tests and risk prediction models. NB is the expected gain or loss in utility of treating or testing relative to not treating...

www.jclinepi.com

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